TWAS hub - MYBPHL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Liver Hepatocellular Carcinoma	0.091	0.045	1.3e-03	0.066	0.064	0.061	NA	0.062	5.0e-04	5.7e-04	7.7e-04	NA	7.0e-04
2	TCGA	Ovarian Serous Cystadenocarcinoma	0.157	0.054	2.9e-10	0.179	0.162	0.166	NA	0.166	3.2e-12	4.3e-11	2.3e-11	NA	2.3e-11

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
LDL Cholesterol	107.8	170.6	285.6	-16.9	-7.5
High cholesterol (Self-reported)	22.6	40.2	76.9	-8.8	-1.9
Medication: Atorvastatin	22.1	27.3	49.3	-7.0	-2.3
Medication: Cholesterol lowering	16.3	25.4	48.6	-7.0	-1.5
Cholesterol lowering medication	15.8	23.3	42.6	-6.5	-2.0
Impedance of leg (left)	12.8	62.4	74.6	-7.1	-8.6
Impedance of leg (right)	12.4	60.0	69.7	-7.1	-8.3
Impedance of whole body	11.3	57.7	62.9	-7.2	-7.9
Father’s age at death	10.9	14.6	20.6	4.5	2.9
Impedance of arm (right)	10.2	47.7	49.1	-6.8	-7.0
Neck or shoulder pain in last month	9.8	14.0	15.8	-4.0	-3.5
Medication: Simvastatin	9.6	14.0	27.4	-5.2	-0.8
Intelligence (Savage-Jansen 2018)	8.1	24.8	37.2	3.5	6.1
Coronary Artery Disease (CAD)	8.0	9.5	16.2	-4.0	-1.7
Impedance of arm (left)	8.0	37.1	37.5	-6.1	-6.1
Verbal and Numeric Reasoning (VNR)	6.9	16.5	25.5	2.8	5.0
Qualifications: None of the above	6.9	14.8	20.4	-3.0	-4.5
Birth weight of first child	6.8	12.4	13.7	3.7	3.3
Qualifications: College or University degree	6.8	21.3	25.8	4.1	5.1
Fluid intelligence score	6.7	13.9	20.8	2.6	4.6
Medication: Aspirin	6.1	8.0	13.6	-3.7	-1.5
Angina (self-reported)	5.9	7.7	14.9	-3.9	-0.7
Medication: Aspirin	5.9	7.8	13.6	-3.7	-1.4
Trunk predicted mass	5.5	31.7	37.8	6.2	5.0
Trunk fat-free mass	5.4	31.0	37.6	6.1	5.0
Arm predicted mass (right)	5.4	27.4	31.2	5.6	4.9
Whole body fat-free mass	5.4	30.9	34.9	5.9	5.2
Whole body water mass	5.4	31.1	34.7	5.9	5.2
Angina	5.3	7.0	13.7	-3.7	-0.5
Arm fat-free mass (right)	5.2	26.6	29.6	5.4	4.9
HDL Cholesterol	5.1	8.5	15.6	3.9	1.2
Noisy workplace	5.1	6.3	9.8	-1.7	-3.1
Medication: Ventolin 100micrograms inhaler	5.1	6.6	6.7	2.6	2.5
Leg fat-free mass (right)	5.0	26.5	27.5	5.2	5.0
Leg predicted mass (right)	4.7	25.2	26.1	5.1	4.9
Pack years adult smoking proportion	4.5	6.9	7.1	-2.7	-2.6
Stomach or abdominal pain in last month	4.5	5.6	5.8	-2.3	-2.4
Leg predicted mass (left)	4.5	23.7	24.2	4.8	4.9
Number of full brothers	4.5	5.7	6.2	-2.3	-2.5
Arm predicted mass (left)	4.5	23.1	26.2	5.1	4.5
Leg fat-free mass (left)	4.4	23.3	23.9	4.8	4.9
Medication for pain relief, constipation, heartburn	4.4	7.6	13.2	3.6	1.4
Basal metabolic rate	4.3	23.9	25.9	5.1	4.7
Arm fat-free mass (left)	4.2	21.3	23.2	4.8	4.4
Bipolar Disorder (2018)	4.1	6.5	7.2	2.7	2.4
Heart disease (siblings)	4.1	5.0	8.4	-2.9	-1.3
Medication for cholesterol	4.0	6.0	11.0	3.3	1.0
Heart attack/myocardial infarction (self-reported)	3.9	5.0	9.7	-3.1	-0.5
Pack years of smoking	3.8	5.6	5.8	-2.4	-2.3
Respiratory disease	3.7	8.2	9.5	2.6	3.1
Heart attack	3.7	4.7	9.2	-3.0	-0.4
Comparative body size at age 10	3.7	10.2	15.9	2.1	4.0
BMI	3.6	20.6	33.1	2.9	5.8
Ever smoked	3.6	6.3	6.3	2.5	2.5
Reason for reducing amount of alcohol drunk: Health precaution	3.5	4.1	4.1	2.0	2.0
Major Depression (MDD)	3.4	4.1	4.6	2.1	1.9
Medication for cholesterol, blood pressure or diabetes	3.3	5.4	10.9	3.3	-0.0
Sensitivity / hurt feelings	3.2	5.5	7.7	1.8	2.8
Myopia	3.1	4.5	4.6	2.1	2.1
Serious illness, injury or assault to yourself	3.0	3.6	3.8	-1.9	-2.0
Multivitamins +/- minerals	3.0	3.8	5.0	1.6	2.2
Supplements: Glucosamine	2.9	3.8	3.8	2.0	2.0
Smoking status: Previous	2.8	4.2	5.6	1.7	2.4
Average weekly beer plus cider intake	2.8	4.0	5.7	-1.5	-2.4
Pain experienced in last month	2.8	4.7	4.8	2.1	2.2
Birth weight	2.7	5.9	8.7	1.8	3.0
Cardiovascular Disease	2.6	8.5	16.8	-4.1	0.5
Chest pain or discomfort	2.6	3.8	5.5	-2.3	-1.5
Back pain experienced in last month	2.6	3.8	5.6	-1.4	-2.4
Heel T-Score	2.4	19.5	22.9	4.8	4.0
Average weekly fortified wine intake	2.4	2.8	3.1	1.8	1.6
Length of working week for main job	2.3	2.5	4.7	0.5	2.2
Average weekly champagne plus white wine intake	2.3	3.1	4.2	1.5	2.0
Other serious medical condition/disability diagnosed by doctor	2.2	2.8	5.6	-2.4	-0.1
Number of live births	2.2	3.1	4.6	-1.3	-2.1
Leg pain on walking	2.2	2.7	2.9	-1.7	-1.6
Chronotype (morning person)	2.1	4.8	5.0	2.1	2.2
Body mass index (BMI)	2.1	9.1	14.6	1.9	3.8
Commuting to job workplace: Walk	2.1	2.3	4.2	0.6	2.0
Alcohol intake versus 10 years previously	2.0	3.1	3.6	1.6	1.9
Qualifications: NVQ or HND or HNC or equivalent	2.0	2.5	3.1	-1.4	-1.8
Illnesses of father: High blood pressure	2.0	2.4	2.6	1.6	1.5
Schizophrenia vs Biploar Disorder	1.9	2.5	2.7	-1.5	-1.6
Falls in the last year	1.9	2.5	3.7	-1.2	-1.9
Qualifications: A levels/AS levels or equivalent	1.9	4.1	4.8	1.9	2.2
Exposure to tobacco smoke at home	1.9	2.2	3.7	-1.9	-0.8
Commuting to job workplace: Car/motor vehicle	1.9	2.1	2.8	-1.2	-1.7
Smoking status: Current	1.9	3.1	5.8	-0.5	-2.4
Fasting Glucose	1.8	2.2	2.2	1.5	1.5
Waist circumference	1.8	6.6	8.7	2.1	3.0
Weight	1.8	8.8	10.2	2.7	3.2
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	4.8	1.0	2.2
Medication: Allopurinol	1.8	2.4	2.9	1.7	1.4
Eye problems/disorders: Cataract	1.8	2.1	2.2	-1.5	-1.4
Commuting to job workplace: Public transport	1.8	2.2	2.8	1.2	1.7
Lupus	1.7	2.5	3.3	1.3	1.8
Number of treatments/medications taken	1.7	3.1	6.2	-2.5	0.0
Asthma	1.7	3.4	5.0	1.4	2.2
Asthma (self-reported)	1.7	3.3	4.8	1.3	2.2
Relative age voice broke	1.6	2.5	3.5	1.2	1.9
Illnesses of mother	1.6	1.9	3.2	-0.8	-1.8
Pulse rate, automated reading	1.6	5.3	8.1	-2.8	-1.6
Hair/balding pattern: Pattern 3	1.5	2.3	2.6	1.6	1.4
Exposure to tobacco smoke outside home	1.5	2.1	3.1	-1.0	-1.8
Qualifications: nursing, teaching	1.5	2.4	3.7	1.0	1.9
Medication: Lisinopril	1.5	2.0	3.6	0.5	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	4.9	2.2	1.2
Past tobacco smoking	1.4	2.6	2.7	-1.6	-1.6
Prospective memory result	1.4	1.7	3.0	1.7	0.7
Medication: Seretide 50 evohaler	1.4	1.6	3.2	1.8	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	2.3	-0.9	-1.5
Illnesses of father: Heart disease	1.4	2.0	2.5	-1.6	1.2
Age at First Birth	1.3	2.0	3.1	1.8	0.9
Blood Red Count	1.3	12.5	16.5	2.9	4.1
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	1.8	1.1	1.4
High blood pressure (mother)	1.3	1.8	3.6	-0.1	1.9
Breastfed as a baby	1.3	1.6	2.5	1.6	0.9
Handedness (chirality/laterality): Left-handed	1.3	1.6	2.3	0.9	1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	2.6	-0.4	-1.6
Number of self-reported non-cancer illnesses	1.3	2.2	4.3	-2.1	0.4
Ever taken oral contraceptive pill	1.3	1.4	1.7	1.3	1.1
Hand grip strength (left)	1.2	3.2	5.7	2.4	0.8
Supplements: Zinc	1.2	1.3	1.4	1.2	1.1
Townsend deprivation index at recruitment	1.2	1.7	3.4	-0.2	1.9
Current tobacco smoking	1.2	2.0	4.0	-0.3	-2.0
Nervous feelings	1.2	2.2	2.3	1.5	1.5
Wheeze or whistling in the chest in last year	1.2	2.2	2.9	1.7	1.2
Alzheimer’s Disease (in father)	1.1	1.1	2.1	-0.4	-1.5
Breast Cancer	1.1	2.6	2.8	-1.6	-1.7
Age when periods started (menarche)	1.1	2.6	3.5	-1.9	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.6	4.2	2.0	1.0
Neuroticism score	1.1	2.4	2.6	1.5	1.6
Medication: Omeprazole	1.1	1.3	2.4	-1.6	-0.4
Miserableness	1.1	2.0	3.0	-1.0	-1.7
Irritability	1.1	1.9	2.7	1.0	1.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	2.5	-1.6	-0.4
Bipolar Disorder or Schizophrenia	1.0	2.5	2.6	1.6	1.6
Lung FEV1/FVC ratio	1.0	5.2	10.3	-3.2	-0.1
Neuroticism	1.0	2.4	3.2	1.3	1.8
Systolic blood pressure, automated reading	1.0	2.9	3.4	1.6	1.9
Maternal smoking around birth	1.0	1.5	2.1	-1.4	-0.9
High blood pressure	1.0	2.9	3.1	1.6	1.8
Illnesses of siblings	1.0	1.5	2.8	1.7	0.3
Time employed in main current job	1.0	1.2	1.7	-0.8	-1.3
Medication: Lansoprazole	1.0	1.1	2.1	-0.4	-1.4
Lung cancer (father)	1.0	1.2	2.1	-0.4	-1.5
Headache pain in last month	1.0	1.7	2.2	-1.5	-1.1
Pulse wave peak to peak time	1.0	1.1	1.5	1.2	0.9
Medication: Blood pressure	1.0	1.8	3.4	0.5	1.8
Number of full sisters	1.0	1.3	1.5	-1.0	-1.2
Illnesses of siblings: Diabetes	1.0	1.2	2.2	-0.4	-1.5
Osteoporosis (self-reported)	1.0	1.2	1.2	-1.1	-1.1
Fractured/broken bones in last 5 years	1.0	1.3	1.3	-1.1	-1.1
Alcohol drinker status: Previous	1.0	1.1	1.6	-0.8	1.3
Neuroticism (Nagel 2018)	0.9	2.0	2.1	1.4	1.4
Smoking Status	0.9	2.1	3.7	1.9	0.7
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.0	-1.4	-0.4
Arm fat mass (right)	0.9	3.6	6.2	0.9	2.5
Peak expiratory flow (PEF)	0.9	2.2	2.9	-1.2	-1.7
Eye problems/disorders: None of the above	0.9	1.1	1.3	0.9	1.1
Age at last live birth	0.9	1.3	1.5	1.2	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	3.2	1.8	0.7
Long-standing illness, disability or infirmity	0.9	1.3	2.7	-1.6	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	1.4	-1.2	-1.2
Guilty feelings	0.9	1.3	1.8	0.9	1.3
Wears glasses or contact lenses	0.9	1.1	1.6	1.3	0.7
Supplements: Fish oil (including cod liver oil)	0.9	1.2	1.6	1.3	0.9
Worry (Nagel 2018)	0.8	1.7	2.2	1.1	1.5
Primary Biliary Cirrhosis	0.8	1.1	1.1	-1.0	-1.1
Waist Hip Ratio (WHR)	0.8	3.5	6.4	2.5	0.7
Vitamin and mineral supplements	0.8	1.1	1.5	-0.9	-1.2
Hand grip strength (right)	0.8	2.1	4.2	2.1	0.1
Qualifications: CSEs or equivalent	0.8	1.1	1.1	-1.0	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	1.3	0.7	1.1
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	1.6	-1.3	-0.6
Gout (self-reported)	0.8	1.2	2.2	1.5	0.4
Leg fat percentage (right)	0.8	3.0	5.2	-2.3	-0.9
Number of children fathered	0.8	1.0	1.6	-0.5	-1.3
Age at first live birth	0.8	1.4	2.7	1.7	0.4
Migraine (self-reported)	0.8	1.0	2.1	-1.4	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.0	-1.0	-0.9
Illnesses of father: None of the above (group 1)	0.8	1.0	1.3	-0.9	-1.2
Arm fat mass (left)	0.8	3.4	6.0	0.9	2.4
Mother’s age at death	0.8	1.0	1.1	0.9	1.1
Mean Putamen Volume	0.7	0.8	1.1	-0.8	-1.0
HbA1C	0.7	0.8	1.1	1.1	0.7
Blood Platelet Count	0.7	7.8	8.8	-2.6	-3.0
Allergy or Eczema	0.7	2.0	2.6	1.6	1.1
Medication: Co-codamol	0.7	0.8	0.9	-1.0	-0.8
Trunk fat percentage	0.7	2.6	4.8	-2.2	-0.7
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	1.3	-1.2	-0.6
Hair/balding pattern: Pattern 2	0.7	0.8	0.9	0.9	1.0
Pain all over the body in last month	0.7	0.8	1.1	-0.7	1.1
Pulse wave Arterial Stiffness index	0.7	0.8	0.9	-1.0	-0.8
Tense / ‘highly strung’	0.7	1.2	2.2	0.4	1.5
Body fat percentage	0.7	2.8	5.2	-2.3	-0.6
Hypertension (Self-reported)	0.7	2.0	2.7	1.2	1.6
Osteoarthritis (self-reported)	0.7	0.9	1.6	1.2	0.6
Tinnitus: Yes, now most or all of the time	0.7	0.9	1.3	-1.2	0.6
Pain type(s) experienced in last month: Hip pain	0.7	0.9	1.1	-1.1	-0.8
Risk taking	0.7	1.0	2.0	1.4	0.3
Ever had hysterectomy (womb removed)	0.6	0.7	0.9	-0.7	-0.9
Diabetes (father)	0.6	0.7	0.9	0.8	-0.9
Taking other prescription medications	0.6	0.9	1.6	-0.4	1.3
Financial difficulties in last 2 years	0.6	0.8	1.7	-0.1	1.3
Mouth/teeth dental problems: Dentures	0.6	1.0	1.7	1.3	0.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.3	0.4	1.1
Chronic bronchitis/emphysema (mother)	0.6	0.8	1.0	-0.7	-1.0
Health satisfaction	0.6	0.8	1.6	-1.3	0.1
Alcohol intake frequency.	0.6	1.3	2.6	0.3	1.6
Average weekly red wine intake	0.6	0.9	0.9	-0.9	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.0	1.0	0.7
Leg fat percentage (left)	0.6	2.1	3.6	-1.9	-0.7
Commuting to job workplace: Cycle	0.6	0.7	0.8	0.9	0.8
Reaction Time	0.5	0.9	1.6	-0.3	-1.3
Triglycerides	0.5	0.8	1.5	-1.2	0.1
Ulcerative Colitis	0.5	0.7	0.8	-0.9	-0.7
Blood Eosinophil Count	0.5	3.9	5.6	1.5	2.4
Tanning	0.5	6.5	11.0	3.3	1.4
Relative age of first facial hair	0.5	1.1	1.3	-0.9	-1.2
Ever used hormone-replacement therapy (HRT)	0.5	0.6	1.2	-0.1	-1.1
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.5	-1.2	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.5	0.1	1.2
Medication: Paracetamol	0.5	0.8	1.3	-1.1	-0.6
Glaucoma (self-reported)	0.5	0.6	1.0	1.0	0.4
High blood pressure (siblings)	0.5	0.7	1.1	-1.1	0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.2	0.2	1.1
Mean time to correctly identify matches	0.5	0.9	1.7	-0.2	-1.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	0.8	-0.7	-0.9
Mood swings	0.5	0.9	1.5	1.2	0.5
Hearing aid user	0.5	0.6	1.2	0.1	-1.1
Number of operations (self-reported)	0.5	0.7	1.1	-1.1	-0.5
Diastolic blood pressure, automated reading	0.5	1.4	2.5	1.6	0.6
Unable to work because of sickness or disability	0.5	0.7	1.2	-1.1	0.4
Height	0.4	7.2	14.2	3.8	-0.5
Hypothyroidism (self reported)	0.4	0.8	1.2	0.7	1.1
Type 2 Diabetes (T2D) (2018)	0.4	0.8	0.9	0.9	0.8
Allergy	0.4	0.9	1.2	-1.1	-0.7
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.9	-0.9	-0.4
Medication: Amlodipine	0.4	0.6	1.0	-1.0	-0.4
Supplements: Vitamin C	0.4	0.4	0.8	0.9	0.2
Financial situation satisfaction	0.4	0.5	1.0	-1.0	-0.3
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.9	-0.6	-1.4
Supplements: Calcium	0.4	0.4	0.4	-0.6	-0.7
Depression (Nagel 2018)	0.3	0.4	0.7	0.3	0.8
Crohns Disease (2017)	0.3	0.7	0.8	0.9	0.7
Prostate Cancer	0.3	0.4	0.7	-0.8	0.3
Medication: Metformin	0.3	0.4	0.7	0.3	-0.9
Diabetes (mother)	0.3	0.4	0.7	0.8	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	0.6	0.7	0.8
Medication: Atenolol	0.3	0.3	0.6	-0.7	-0.3
Chronic bronchitis/emphysema (father)	0.3	0.3	0.5	0.7	0.4
Hearing difficulty/problems with background noise	0.3	0.5	0.5	-0.7	-0.7
Arm fat percentage (right)	0.3	1.2	1.5	-1.2	0.9
Worrier / anxious feelings	0.3	0.6	0.6	0.8	0.7
Happiness	0.3	0.4	0.7	0.8	0.3
Standing height	0.3	2.9	5.2	2.3	-0.8
Forced vital capacity (FVC), Best measure	0.3	1.2	2.4	1.6	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.6	0.3	0.8
Shortness of breath walking on level ground	0.3	0.4	0.8	-0.9	-0.2
Comparative height size at age 10	0.3	1.5	2.4	1.6	-0.8
Overall health rating	0.3	0.7	1.3	-1.1	0.4
Had major operations	0.3	0.3	0.4	-0.7	-0.5
Knee pain experienced in last month	0.3	0.5	0.8	-0.5	-0.9
Arm fat percentage (left)	0.3	1.2	1.8	-0.8	1.3
Ever had bowel cancer screening	0.3	0.3	0.4	-0.6	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.1	0.4	1.0
Medication: Bendroflumethiazide	0.3	0.5	0.9	0.9	0.3
Ever depressed for a whole week	0.3	0.4	0.8	0.0	0.9
Ovarian Cancer	0.2	0.3	0.5	-0.1	-0.7
Systolic Blood Pressure	0.2	0.9	0.9	0.9	1.0
Lung FVC	0.2	0.9	1.1	0.9	-1.0
Hair Pigment	0.2	4.6	5.4	-1.9	-2.3
Hearing difficulty/problems: Yes	0.2	0.3	0.3	0.5	-0.6
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.3	0.6	0.3
Medication for hormone replacement therapy	0.2	0.2	0.4	-0.6	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.4	-0.1	0.7
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.3	-0.3	-0.6
Forced vital capacity (FVC)	0.2	0.8	1.2	0.6	-1.1
Hip circumference	0.2	1.0	1.9	-0.1	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.5	0.1	0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.2	-0.3	-1.1
Pulse rate	0.2	0.3	0.5	-0.7	-0.1
Hair/balding pattern: Pattern 4	0.2	0.4	0.6	-0.8	-0.5
Heart disease (mother)	0.2	0.3	0.6	-0.8	-0.2
Leg fat mass (right)	0.2	0.7	1.3	-0.1	1.1
Family relationship satisfaction	0.2	0.3	0.4	-0.4	0.7
Breast cancer (self-reported)	0.2	0.3	0.5	-0.2	0.7
Medication: Paracetamol	0.2	0.3	0.6	-0.8	0.1
Leg fat mass (left)	0.2	0.8	1.7	0.1	1.3
Depressed Affect (Nagel 2018)	0.1	0.1	0.3	0.1	-0.5
Alzheimer’s Disease (in mother)	0.1	0.1	0.2	0.0	0.4
Alzheimer’s Disease (including proxy)	0.1	0.1	0.2	-0.0	-0.5
Irritable Bowel Disease (IBD)	0.1	0.3	0.4	0.6	0.4
Ulcerative Colitis (UC)	0.1	0.2	0.3	0.5	0.5
Body Mass Index (BMI) (2010)	0.1	0.1	0.2	0.5	-0.2
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	0.5	-0.2
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.3	0.2	0.6
Severe depression (siblings)	0.1	0.1	0.1	-0.3	-0.2
Medication: Levothyroxine sodium	0.1	0.2	0.2	-0.4	0.5
Sitting height	0.1	1.0	1.8	1.3	0.5
Trunk fat mass	0.1	0.5	0.8	-0.3	0.9
Alcohol usually taken with meals	0.1	0.1	0.2	-0.3	0.4
Had menopause	0.1	0.1	0.2	0.4	-0.1
Had other major operations	0.1	0.1	0.2	-0.3	0.4
Medication: Ramipril	0.1	0.1	0.2	-0.4	-0.3
Depression (self-reported)	0.1	0.1	0.2	-0.3	-0.4
Pulse wave reflection index	0.1	0.1	0.2	0.1	-0.5
Loud music exposure frequency	0.1	0.2	0.3	0.5	0.2
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.3	-0.0	0.6
Worry too long after embarrassment	0.1	0.1	0.2	0.4	0.2
Emphysema/chronic bronchitis	0.1	0.2	0.3	0.6	-0.1
Medication: Ibuprofen	0.1	0.1	0.2	-0.4	-0.1
Whole body fat mass	0.1	0.5	0.9	-0.2	0.9
Suffer from ‘nerves’	0.1	0.2	0.4	-0.3	-0.6
Loneliness, isolation	0.1	0.1	0.2	-0.5	-0.1
Diabetes diagnosed by doctor	0.1	0.2	0.4	0.1	0.6
Mineral and other dietary supplements	0.1	0.1	0.1	-0.2	-0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	0.4	0.4
Alcohol drinker status: Never	0.1	0.1	0.1	0.3	0.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	0.3	-0.2
Age started oral contraceptive pill	0.1	0.1	0.2	-0.2	-0.4
Basal cell carcinoma (self-reported)	0.1	0.1	0.1	-0.1	0.3
Schizophrenia (2018)	0.0	0.0	0.0	-0.1	0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.1	0.1	0.1	0.4
Neuroticism (2016)	0.0	0.0	0.0	0.0	0.1
Rheumatoid Arthritis	0.0	0.0	0.0	-0.2	-0.2
Schizophrenia (2014)	0.0	0.0	0.0	-0.2	0.1
Blood White Count	0.0	0.2	0.4	0.6	0.2
Average weekly spirits intake	0.0	0.0	0.0	-0.0	0.2
Fed-up feelings	0.0	0.1	0.1	0.4	-0.1
Number of incorrect matches in round	0.0	0.0	0.1	0.0	-0.3
Mouth/teeth dental problems	0.0	0.1	0.1	0.3	0.1
Diabetes (self-reported)	0.0	0.0	0.1	0.2	0.1
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.0	0.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.3	0.5	-0.0
Blood clot in the leg (DVT)	0.0	0.0	0.0	0.2	-0.0
Friendships satisfaction	0.0	0.1	0.1	-0.1	0.3
Medication: Gliclazide	0.0	0.0	0.0	-0.2	-0.1
Medication: Blood pressure	0.0	0.1	0.1	-0.0	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.0	0.1	0.1	0.0	-0.3

Hub : Genes

MYBPHL

Models

Trait associations