Hub : Genes

MPZL2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0530 0.0240 6.6e-03 0.025 0.012 0.006 0.015 0.026 4.6e-04 1.2e-02 6.0e-02 5.5e-03 3.1e-04
2 GTEx Skin Sun Exposed Lower leg 0.0770 0.0290 2.2e-03 0.047 NA 0.049 NA 0.058 8.7e-05 NA 5.9e-05 NA 1.4e-05
3 NTR Blood 0.0554 0.0126 6.0e-12 0.056 0.038 0.047 0.050 0.056 1.3e-17 3.3e-12 6.4e-15 7.1e-16 1.7e-17
4 YFS Blood 0.2179 0.0275 0.0e+00 0.248 0.248 0.267 0.244 0.260 2.5e-80 3.4e-80 2.1e-87 1.0e-78 1.2e-84
5 TCGA Glioblastoma Multiforme 0.1160 0.0680 2.7e-03 0.036 0.027 0.062 NA 0.024 3.0e-02 5.1e-02 5.9e-03 NA 6.3e-02
6 TCGA Kidney Renal Clear Cell Carcinoma 0.0376 0.0286 6.2e-03 0.019 0.018 0.025 NA 0.006 2.8e-03 3.8e-03 6.4e-04 NA 6.6e-02
7 TCGA Prostate Adenocarcinoma 0.0437 0.0262 1.4e-03 0.038 0.037 0.029 NA 0.034 7.3e-05 9.2e-05 4.2e-04 NA 1.6e-04
8 TCGA Thyroid Carcinoma 0.1820 0.0620 7.6e-11 0.117 0.121 0.131 NA 0.104 2.0e-11 8.4e-12 1.1e-12 NA 2.8e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.9 3.0 11.2 -1.0 -0.7 0.9 1.2 0.6 -3.4 2.2 2.1
Bipolar Disorder or Schizophrenia 1.8 4.3 8.1 -0.5 -1.4 1.9 2.2 0.8 -2.8 2.8 2.7
Depressed Affect (Nagel 2018) 0.8 1.6 3.1 -0.6 -1.2 1.7 1.8 1.2 -1.7 0.3 0.9
Depression (Nagel 2018) 1.2 1.8 4.7 -0.2 -1.2 2.2 2.0 0.2 -1.1 1.6 1.0
Intelligence (Savage-Jansen 2018) 0.5 1.5 2.9 1.5 0.8 -1.7 -1.6 -1.4 0.8 -0.2 0.8
Neuroticism (Nagel 2018) 1.2 2.8 5.8 -1.2 -1.8 2.3 2.4 0.9 -2.0 1.0 0.7
Schizophrenia (2018) 1.0 2.0 3.4 0.1 -1.3 1.8 1.8 0.6 -1.1 1.8 1.8
Schizophrenia vs Biploar Disorder 0.5 0.6 1.7 0.2 -0.2 1.3 1.2 0.3 0.7 -1.1 -0.1
Worry (Nagel 2018) 1.3 2.8 5.2 -1.3 -1.7 2.3 2.2 -0.2 -1.5 2.3 0.5
Alzheimer’s Disease (in mother) 0.1 0.1 0.3 -0.6 -0.1 0.1 0.2 0.4 -0.3 0.2 -0.2
Alzheimer’s Disease (in father) 1.7 1.8 5.9 -2.4 -1.6 0.9 1.0 -0.8 -1.9 -0.3 -0.0
Alzheimer’s Disease (including proxy) 1.2 1.7 5.9 -2.4 -1.6 0.9 0.9 -1.1 -1.2 -0.5 -0.9
Crohns Disease (2017) 1.6 3.4 7.8 1.7 2.2 -2.8 -2.8 1.0 1.7 0.3 -0.8
Irritable Bowel Disease (IBD) 2.6 6.2 12.2 3.0 3.2 -3.4 -3.5 1.6 2.1 -0.2 -0.5
Ulcerative Colitis (UC) 2.6 4.9 9.0 2.8 3.0 -2.8 -2.9 1.7 1.3 -0.8 -0.3
Major Depression (MDD) 1.2 1.5 4.0 2.0 1.4 -0.3 -0.2 1.8 0.5 0.8 1.2
Reaction Time 1.0 1.8 3.5 -1.0 -0.1 -1.8 -1.8 -1.4 1.4 -0.0 -1.9
Verbal and Numeric Reasoning (VNR) 0.6 1.5 3.9 2.0 1.8 -1.2 -1.0 1.4 0.3 0.4 0.4
Breast Cancer 0.2 0.5 1.1 1.1 0.8 -0.8 -0.8 0.0 0.9 0.0 -0.1
Ovarian Cancer 0.4 0.6 1.7 0.8 0.5 0.2 0.3 1.0 -0.4 1.3 1.0
Prostate Cancer 1.0 1.3 6.5 1.6 1.1 -0.2 0.1 2.5 0.6 0.2 -0.3
Age at First Birth 0.7 1.0 1.9 -1.1 -1.4 1.2 1.0 -1.3 0.2 0.8 -0.4
Bipolar Disorder (2011) 1.5 1.5 4.2 1.1 0.9 -1.1 -0.6 0.8 -1.0 1.6 2.0
Body Mass Index (BMI) (2010) 1.0 1.3 3.8 -0.1 0.6 -1.1 -1.3 0.3 1.0 -1.9 -1.6
Coronary Artery Disease (CAD) 0.6 0.8 1.8 0.9 1.0 -1.3 -1.0 1.2 0.1 -0.1 0.2
Crohns Disease (2012) 0.9 1.5 4.2 0.7 0.9 -1.9 -2.1 0.1 1.0 -0.6 -1.0
Mean Putamen Volume 0.9 1.0 2.4 -1.5 -1.2 1.1 1.2 -0.5 -0.1 -0.6 -0.8
Fasting Glucose 1.6 1.9 4.9 1.1 1.4 -2.2 -2.0 0.6 -1.2 -0.6 0.9
HbA1C 0.8 0.9 3.2 0.9 1.2 -0.4 -0.8 0.5 0.6 -1.8 -0.1
HDL Cholesterol 0.4 0.7 1.8 0.2 -0.3 1.1 1.3 0.7 -0.3 1.3 0.4
LDL Cholesterol 1.4 2.3 6.9 1.8 1.0 0.7 0.8 2.6 -1.1 1.5 1.6
Lupus 0.6 0.9 2.3 1.2 -0.3 1.4 1.5 0.2 0.6 0.7 1.0
Neuroticism (2016) 0.3 0.4 1.5 -1.2 -0.2 0.1 0.2 0.5 -0.3 -0.2 -1.2
Primary Biliary Cirrhosis 0.2 0.2 0.8 -0.2 -0.1 -0.2 -0.3 -0.6 -0.5 0.4 0.9
Rheumatoid Arthritis 0.2 0.3 0.8 -0.1 -0.5 0.1 0.3 -0.5 -0.8 0.2 0.9
Schizophrenia (2014) 1.8 4.0 6.6 -0.3 -1.2 2.4 2.6 1.4 -2.1 2.5 2.3
Triglycerides 0.5 0.8 3.6 0.9 0.7 -0.2 0.1 1.9 0.1 1.2 0.5
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.9 -0.6 -0.3 0.3 0.4 0.8 -1.4 1.4 0.6
Ulcerative Colitis 0.9 1.4 3.0 1.5 1.3 -1.6 -1.7 0.6 -0.4 0.2 1.1
Blood Eosinophil Count 0.4 3.4 10.0 -0.8 -1.0 1.8 1.8 0.2 -2.0 3.2 2.1
Blood Platelet Count 0.4 4.9 9.9 -3.1 -3.0 2.9 2.9 -1.2 -1.4 0.3 -0.8
Blood Red Count 0.4 4.0 14.1 0.3 1.9 -0.8 -0.4 2.8 -3.8 1.8 1.5
Blood White Count 2.5 18.9 42.5 -6.0 -6.5 2.9 2.8 -6.4 -2.7 2.5 0.7
Heel T-Score 0.5 3.8 9.4 -1.2 1.0 -2.0 -2.6 -1.6 0.6 -3.1 -2.3
BMI 1.1 6.3 13.2 -0.5 1.6 -3.4 -3.6 -0.4 1.9 -3.5 -2.6
Height 0.1 2.1 6.0 1.6 2.4 -1.2 -1.6 1.4 0.3 -1.5 -0.1
Waist Hip Ratio (WHR) 0.4 1.8 4.4 1.0 2.0 -2.1 -1.9 1.0 0.6 0.6 -0.4
Systolic Blood Pressure 0.5 2.7 6.0 1.5 2.4 -2.2 -2.5 -0.2 1.5 -0.3 0.6
Smoking Status 0.7 1.7 5.4 0.4 1.5 -2.3 -2.2 -0.2 0.6 0.0 -0.6
Allergy or Eczema 1.6 4.3 8.9 -2.2 -3.0 2.2 2.2 -1.9 -2.1 1.6 0.7
Cardiovascular Disease 0.5 1.6 7.6 -2.8 -0.6 -0.3 -0.4 -1.6 -0.5 0.6 -1.2
Hypothyroidism (self reported) 1.2 2.8 8.4 -0.8 -1.5 2.9 2.8 0.2 -1.3 1.1 0.5
Respiratory disease 0.2 0.4 1.4 -1.2 -0.2 0.2 0.6 0.1 -0.5 1.0 0.3
Type 2 Diabetes (T2D) (2018) 0.6 1.1 3.1 -1.1 0.1 -1.0 -1.0 -1.0 -1.8 0.1 1.2
Lung FEV1/FVC ratio 0.3 1.6 6.2 -1.0 -0.8 -0.3 -0.4 -0.3 0.7 -2.1 -2.5
Lung FVC 0.1 0.5 0.9 -0.9 -0.8 0.5 0.4 -1.0 -0.6 -0.6 0.6
Neuroticism 0.8 1.8 3.2 -0.8 -0.9 1.5 1.7 1.6 -1.8 1.3 0.4
Chronotype (morning person) 0.1 0.3 0.9 0.1 0.2 0.4 0.4 0.5 0.1 -0.9 -0.7
Hair Pigment 0.1 1.8 2.9 -0.3 -1.7 1.6 1.6 -1.0 -0.1 1.6 1.5
Tanning 0.1 1.8 4.6 2.1 0.9 0.5 0.4 2.0 0.2 1.5 1.4
Hand grip strength (left) 0.3 0.8 2.7 1.0 1.7 -0.1 -0.5 0.5 0.6 -0.8 1.2
Number of treatments/medications taken 1.1 1.9 5.4 -1.9 -1.3 0.9 1.1 -0.4 -1.5 2.3 0.5
Average weekly spirits intake 2.9 3.6 8.1 2.3 2.8 -1.7 -2.0 1.8 1.9 -0.7 -0.8
Sensitivity / hurt feelings 0.3 0.5 1.8 -1.4 -1.1 -0.1 0.0 0.4 -0.8 0.3 -0.5
Frequency of depressed mood in last 2 weeks 0.4 0.6 1.8 -0.2 -0.3 1.3 1.2 0.6 -0.6 0.7 0.5
Hearing difficulty/problems: Yes 0.8 1.2 3.2 -0.5 -0.6 1.2 1.2 1.0 1.2 -0.9 -1.8
Relative age of first facial hair 0.8 1.7 3.2 -1.0 -1.8 1.5 1.6 -1.1 -0.4 1.8 0.3
Other serious medical condition/disability diagnosed by doctor 1.7 2.2 5.4 1.1 1.5 -2.3 -2.2 0.8 1.3 -0.7 -1.0
Ever used hormone-replacement therapy (HRT) 0.1 0.1 0.6 -0.5 -0.1 0.1 0.2 0.1 0.4 0.3 -0.8
Ever had hysterectomy (womb removed) 1.1 1.3 5.4 0.9 1.9 -0.2 -0.2 2.3 -0.1 -0.1 0.5
Systolic blood pressure, automated reading 0.7 1.9 5.1 2.0 2.3 -1.0 -1.2 1.1 0.4 -0.8 1.4
Eye problems/disorders: Diabetes related eye disease 1.3 1.5 5.4 0.0 -0.3 -0.1 0.2 0.1 -2.1 1.4 2.3
Angina 1.1 1.4 5.3 -1.7 -1.2 -0.4 -0.5 -2.3 0.2 -1.0 -0.6
Medication for hormone replacement therapy 0.7 0.7 2.1 0.3 0.1 -1.4 -1.4 -1.0 -0.4 0.1 0.8
Vitamin and mineral supplements 1.1 1.5 2.8 0.2 0.8 -1.4 -1.4 -0.0 1.7 -1.6 -1.5
Supplements: Zinc 0.2 0.2 0.4 0.6 0.2 0.3 0.5 0.5 0.4 0.3 0.6
Medication: Co-codamol 1.3 1.5 3.6 -0.1 1.3 -1.0 -1.2 0.5 1.3 -1.4 -1.9
Medication: Metformin 1.2 1.7 4.0 -0.5 -0.3 0.8 1.1 0.9 -2.0 1.8 1.8
Diabetes (father) 0.2 0.2 0.8 0.3 0.3 -0.0 -0.2 0.7 -0.3 -0.9 0.2
Diabetes (mother) 0.4 0.6 2.1 0.1 0.2 1.1 0.8 -0.0 -0.4 0.4 1.4
Severe depression (siblings) 1.0 1.1 2.5 -1.2 -1.0 0.2 0.2 -1.1 -1.2 1.6 1.1
Pack years adult smoking proportion 0.3 0.5 2.0 0.3 0.9 -0.5 -0.2 1.4 0.8 0.1 -0.3
Impedance of leg (right) 0.3 1.6 5.1 0.5 0.3 1.1 1.4 1.7 -1.1 2.3 0.6
Leg fat-free mass (left) 1.5 7.8 16.1 1.5 2.4 -3.6 -4.0 -0.1 2.5 -3.9 -1.9
Trunk fat percentage 0.8 3.2 6.0 1.7 2.2 -2.4 -2.4 1.8 0.9 -1.1 -1.1
Hand grip strength (right) 0.5 1.4 4.5 1.4 2.1 -0.4 -0.8 0.9 1.4 -1.0 0.2
Townsend deprivation index at recruitment 3.5 4.9 11.3 0.7 1.8 -3.2 -3.4 -0.9 2.1 -2.7 -1.1
Current tobacco smoking 0.4 0.7 2.1 0.6 0.2 -0.7 -0.5 0.1 -1.0 1.1 1.5
Average weekly fortified wine intake 1.5 1.7 6.1 0.3 1.3 -1.4 -1.5 0.1 0.9 -2.5 -0.9
Maternal smoking around birth 0.7 0.9 4.3 0.0 0.8 -0.2 -0.3 0.5 -1.0 2.1 1.0
Fed-up feelings 0.2 0.3 0.9 0.2 -0.7 -0.4 -0.2 0.9 -0.6 -0.6 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.2 0.8 -0.5 -0.2 0.1 -0.2 0.2 0.6 0.1 -0.9
Relative age voice broke 1.7 2.5 4.5 -2.1 -2.1 2.0 1.8 -1.7 -0.4 0.7 -0.7
Taking other prescription medications 0.8 1.2 5.2 -0.6 -0.3 1.1 1.1 0.3 -0.7 2.3 1.0
Age when periods started (menarche) 0.2 0.5 1.1 0.1 0.3 -1.0 -1.0 -0.4 1.0 -0.5 -0.3
Bilateral oophorectomy (both ovaries removed) 0.2 0.3 0.6 0.4 0.6 -0.6 -0.4 0.8 0.3 0.5 -0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.4 1.0 3.0 -0.3 -0.2 -0.3 -0.8 -1.7 0.6 -1.5 -1.2
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 2.7 1.0 1.4 -1.6 -1.6 -0.1 1.0 -0.9 -1.1
Qualifications: CSEs or equivalent 0.4 0.6 1.8 0.4 0.4 -1.4 -1.2 -0.1 0.5 -0.9 0.1
Serious illness, injury or assault to yourself 0.7 0.8 2.5 -1.6 -1.4 -0.1 0.0 -1.1 0.1 0.5 -0.7
High blood pressure 0.2 0.5 1.6 -1.3 -0.1 -0.3 -0.5 -1.3 -0.1 0.4 -0.1
Hayfever, allergic rhinitis or eczema 0.3 0.7 1.6 -1.1 -1.3 0.4 0.5 -1.1 -1.0 0.6 0.0
Multivitamins +/- minerals 0.8 1.1 4.6 1.0 -0.1 0.3 0.4 0.6 -0.8 1.3 2.1
Stomach or abdominal pain in last month 0.2 0.3 1.3 0.4 0.3 0.1 0.2 1.2 -0.6 0.1 0.6
Supplements: Glucosamine 0.6 0.8 2.4 0.7 0.9 0.4 0.5 0.9 1.5 -0.1 -1.1
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 1.4 0.1 -0.7 0.3 0.2 -0.7 0.3 0.1 1.2
Medication: Atenolol 0.1 0.1 0.4 -0.1 0.1 0.6 0.6 0.2 0.1 0.6 -0.2
Medication: Levothyroxine sodium 2.6 4.4 10.3 -0.1 -1.4 3.0 3.2 0.8 -1.4 3.2 1.3
Sitting height 0.5 3.6 7.5 1.0 2.4 -2.3 -2.7 0.6 0.7 -2.6 -1.3
Chronic bronchitis/emphysema (father) 0.1 0.1 0.2 -0.4 0.4 -0.3 -0.4 -0.0 -0.0 -0.1 -0.1
High blood pressure (mother) 1.3 1.8 3.7 1.9 1.6 -1.6 -1.5 1.5 0.8 0.2 0.9
Body mass index (BMI) 1.1 4.6 9.2 1.0 2.1 -2.8 -3.0 0.6 1.8 -2.9 -1.6
Impedance of leg (left) 0.4 1.7 4.9 0.1 -0.0 1.5 1.7 1.5 -1.1 2.2 0.5
Leg predicted mass (left) 1.5 7.8 16.1 1.4 2.4 -3.6 -4.0 -0.2 2.5 -3.9 -1.9
Trunk fat mass 1.3 5.6 11.1 1.8 2.8 -3.2 -3.3 1.5 1.7 -2.1 -1.7
Waist circumference 1.2 4.4 8.4 1.3 2.2 -2.7 -2.9 0.6 1.9 -2.5 -1.7
Number of incorrect matches in round 0.4 0.6 2.0 -0.3 0.1 0.1 0.2 1.1 0.4 -1.4 -1.2
Past tobacco smoking 0.9 1.7 4.3 -0.6 -1.7 1.9 2.1 0.7 -0.8 0.6 0.9
Alcohol usually taken with meals 0.5 0.8 2.7 -1.6 -1.0 0.0 0.2 -0.7 -0.6 -1.1 -0.8
Nervous feelings 0.4 0.8 3.8 -1.9 -0.7 -0.1 -0.1 -0.4 -0.8 0.3 -1.0
Frequency of tenseness / restlessness in last 2 weeks 1.2 1.9 4.8 -2.2 -1.8 1.5 1.3 -0.5 -1.6 0.6 0.3
Hearing difficulty/problems with background noise 0.1 0.2 0.7 -0.3 -0.4 -0.1 -0.1 -0.5 0.8 -0.0 -0.5
Hair/balding pattern: Pattern 2 0.0 0.1 0.2 -0.5 -0.1 -0.1 -0.1 -0.1 0.4 -0.2 -0.1
Had menopause 0.5 0.6 1.7 -0.2 -0.2 1.2 1.3 0.9 -0.8 0.4 0.2
Had other major operations 0.4 0.4 2.4 -0.0 0.4 0.3 0.5 0.7 -0.2 1.6 0.1
Forced vital capacity (FVC) 0.7 2.8 7.4 1.5 1.8 -2.6 -2.7 0.1 0.8 -1.4 0.8
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.7 4.2 -0.3 0.2 -0.8 -1.2 -2.0 0.8 -1.9 -1.6
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.5 -1.2 -1.0 0.6 0.7 -0.0 -0.9 0.1 0.1
Qualifications: None of the above 0.9 2.0 4.0 -1.4 -2.0 1.2 1.1 -1.9 -1.5 1.2 0.5
Financial difficulties in last 2 years 0.5 0.7 3.3 0.7 -0.2 0.1 0.1 -0.1 0.1 1.8 1.4
Mouth/teeth dental problems 0.3 0.5 1.6 0.9 0.1 0.3 0.5 1.0 1.3 -0.0 -0.7
Heart attack 0.2 0.2 0.5 -0.6 -0.4 -0.5 -0.4 -0.3 -0.3 -0.3 0.7
Allergy 0.3 0.8 2.3 1.5 0.7 0.0 -0.1 1.0 1.4 -0.3 -0.4
Pain all over the body in last month 0.6 0.7 2.8 0.8 0.3 -0.3 -0.3 0.9 -0.6 1.7 0.8
Diabetes (self-reported) 0.9 1.4 5.3 -0.4 -0.2 -0.1 0.3 0.3 -2.3 1.0 2.1
Hayfever/allergic rhinitis (self-reported) 1.3 1.7 4.1 -1.9 -2.0 1.2 1.3 -0.7 -1.4 0.3 -0.7
Medication: Ramipril 0.4 0.6 2.0 -1.4 -0.1 -0.6 -0.7 -0.0 0.1 0.2 -1.2
Medication: Simvastatin 0.3 0.4 1.5 -0.7 0.3 0.4 0.6 1.2 -0.6 0.7 -0.2
Fluid intelligence score 0.2 0.5 1.6 1.1 0.6 -0.2 0.0 0.1 0.4 1.3 0.7
Illnesses of siblings 0.2 0.3 0.7 -0.4 -0.8 0.4 0.7 -0.5 0.0 -0.3 -0.4
Neuroticism score 0.5 1.1 2.2 -1.4 -1.2 1.0 1.0 0.9 -1.5 0.5 -0.2
Weight 1.8 8.7 17.5 1.7 3.2 -3.8 -4.2 0.8 2.4 -3.7 -2.1
Impedance of arm (right) 0.7 3.2 12.0 0.5 -1.1 1.0 1.6 1.1 -2.3 3.5 1.5
Arm fat percentage (right) 0.7 2.6 6.1 1.5 1.8 -2.5 -2.4 1.4 0.6 -0.8 -0.7
Trunk fat-free mass 2.0 11.6 24.1 1.5 3.6 -4.2 -4.8 -0.2 3.0 -4.9 -2.0
Hip circumference 1.2 5.0 10.6 1.2 1.9 -2.9 -3.3 0.3 1.8 -3.2 -1.4
Time employed in main current job 0.9 1.1 2.2 -0.6 -1.5 0.1 0.2 -1.4 -1.5 0.1 1.4
Alcohol intake versus 10 years previously 0.5 0.8 2.6 0.0 -0.9 0.4 0.3 -0.5 -1.3 0.8 1.6
Father’s age at death 0.7 0.9 2.6 -0.8 -0.5 0.7 0.7 -0.4 1.4 -0.6 -1.6
Worrier / anxious feelings 0.1 0.3 0.7 -0.5 -0.7 0.4 0.5 -0.2 -0.3 0.9 0.4
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.1 -1.0 -1.0 0.8 0.8 0.1 -0.9 0.5 -0.4
Falls in the last year 0.3 0.5 1.7 0.6 -0.1 0.2 0.3 1.3 0.7 0.8 -0.5
Hair/balding pattern: Pattern 3 0.1 0.2 0.7 0.0 -0.9 0.3 0.3 -0.5 -0.2 -0.3 0.2
Number of live births 1.5 2.2 5.1 1.3 2.0 -0.5 -0.5 2.3 2.0 -0.9 -1.1
Forced expiratory volume in 1-second (FEV1) 0.9 2.9 7.7 1.0 1.4 -2.7 -2.8 0.1 1.2 -2.1 -0.4
Pulse rate 0.1 0.2 0.5 0.6 0.5 -0.2 -0.1 0.7 -0.2 -0.0 0.2
Happiness 0.4 0.5 0.9 -0.7 0.9 0.5 0.3 0.6 0.7 -0.8 -1.0
Noisy workplace 0.1 0.2 0.5 0.1 0.4 0.2 0.3 0.7 0.1 -0.5 -0.5
Qualifications: A levels/AS levels or equivalent 0.4 0.9 2.8 1.3 0.9 -0.4 -0.6 -0.0 -0.3 0.9 1.7
Serious illness, injury or assault of a close relative in last 2 years 0.4 0.4 1.3 0.2 1.1 -0.7 -1.0 0.1 0.4 -0.6 0.0
Mouth/teeth dental problems: Dentures 0.9 1.5 2.4 -1.1 -1.5 1.0 1.1 -1.3 -1.6 0.8 1.1
Asthma 0.1 0.3 1.1 -1.1 0.1 0.4 0.4 -0.1 -0.8 0.3 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 0.6 -0.3 -0.7 0.8 0.7 0.1 0.0 -0.2 -0.2
Medication: Cholesterol lowering 0.4 0.6 1.4 -0.4 1.2 -0.4 -0.4 0.8 -1.0 1.2 0.6
Depression (self-reported) 1.4 1.7 3.7 -0.9 -1.1 1.4 1.4 0.2 -1.7 1.0 1.9
Medication: Lansoprazole 0.5 0.6 2.1 -1.4 -0.7 0.5 0.5 -0.0 -1.0 0.1 -0.6
Prospective memory result 0.9 1.1 2.9 -0.3 0.3 -1.7 -1.6 -0.1 0.4 -1.7 -0.5
Lung cancer (father) 1.7 2.0 5.1 -1.5 -0.6 -0.3 -0.8 -2.0 1.1 -2.3 -1.5
Illnesses of mother 0.7 0.8 2.0 0.6 0.6 -1.0 -0.9 0.0 1.1 -0.9 -1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.8 2.7 6.5 1.0 1.3 -2.4 -2.5 0.0 1.3 -2.1 -0.2
Pulse wave Arterial Stiffness index 2.1 2.4 5.0 1.8 2.2 -1.3 -1.4 1.0 1.4 -1.9 -0.8
Impedance of arm (left) 0.8 3.6 13.3 -0.3 -1.8 1.4 2.0 0.0 -2.2 3.6 1.2
Arm fat mass (right) 1.4 5.9 12.7 1.8 2.7 -3.4 -3.6 1.1 1.8 -2.3 -1.5
Trunk predicted mass 2.0 11.4 23.7 1.4 3.5 -4.1 -4.7 -0.3 3.1 -4.9 -2.1
Standing height 0.6 6.2 11.5 2.1 3.3 -3.1 -3.4 1.0 2.1 -2.4 -1.4
Length of working week for main job 0.6 0.6 1.3 0.0 0.6 -0.7 -0.8 -0.7 0.7 -1.2 -1.1
Exposure to tobacco smoke at home 2.4 2.7 6.2 2.1 1.9 -2.5 -2.2 0.8 1.1 -0.6 -0.1
Breastfed as a baby 0.7 0.9 1.7 1.0 1.1 -0.8 -0.9 0.5 1.3 -1.3 -0.4
Tense / ‘highly strung’ 1.7 2.8 4.8 -1.5 -2.2 1.9 2.0 -0.4 -2.0 1.6 1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 2.5 3.8 5.8 -1.9 -2.4 1.8 1.9 -1.9 -2.1 2.0 1.6
Hair/balding pattern: Pattern 4 0.5 1.2 4.3 -1.6 -0.8 0.8 0.7 -0.8 -2.1 -0.0 0.3
Birth weight of first child 0.6 1.1 3.3 1.1 0.8 -1.7 -1.8 0.3 0.3 -0.9 -0.3
Peak expiratory flow (PEF) 0.8 1.9 3.8 1.1 1.7 -1.6 -1.7 0.8 1.1 -1.9 -0.8
Pulse wave reflection index 0.5 0.6 1.2 -0.5 -1.1 1.0 1.0 -1.0 -0.1 -0.5 -0.4
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.7 0.5 0.5 -0.8 -0.7 0.1 -1.1 0.2 1.3
Loud music exposure frequency 0.6 0.6 1.6 0.4 0.9 -1.3 -1.1 0.3 0.3 -1.0 0.1
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 0.9 -0.3 0.2 -1.0 -0.9 -0.1 -0.7 -0.4 -0.3
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 2.0 -0.8 -0.0 -0.8 -1.0 -1.2 -1.4 0.2 0.7
Blood clot in the leg (DVT) 3.9 5.1 9.4 1.9 3.0 -3.1 -2.8 2.3 1.7 -1.2 -1.2
Medication: Paracetamol 0.7 1.2 3.7 -1.9 -0.5 -0.1 -0.2 -0.8 -0.3 -1.5 -1.5
Headache pain in last month 0.4 0.7 1.5 -1.1 -1.2 0.2 0.4 -0.4 -1.0 -1.0 -0.3
Medication for cholesterol, blood pressure or diabetes 0.2 0.4 1.7 0.3 -1.3 0.6 0.7 -0.5 0.4 -0.3 -0.4
Glaucoma (self-reported) 0.4 0.4 1.3 0.4 1.1 -0.3 -0.1 1.2 -0.6 0.6 0.1
Gout (self-reported) 0.3 0.4 2.0 -0.5 0.5 0.1 -0.4 0.0 -1.4 -0.4 0.3
Hypothyroidism/myxoedema (self-reported) 2.0 3.8 9.7 0.2 -1.3 3.1 3.1 0.5 -1.5 2.0 1.8
Medication: Amlodipine 2.1 2.9 4.8 -2.0 -2.2 1.5 1.5 -2.0 -1.1 2.0 0.5
Medication: Ventolin 100micrograms inhaler 1.2 1.5 3.0 -1.7 -1.3 1.3 1.1 -0.6 -0.9 -1.4 -1.1
Birth weight 0.7 1.5 4.2 0.4 0.9 -0.9 -0.7 1.0 1.8 -1.1 -2.0
Chronic bronchitis/emphysema (mother) 1.4 1.6 4.2 -1.9 -1.0 1.3 1.2 -0.8 -2.1 0.3 -0.3
High blood pressure (siblings) 0.6 0.9 1.7 1.3 1.1 -1.1 -1.2 0.4 0.7 0.4 1.0
Forced vital capacity (FVC), Best measure 0.8 3.1 8.0 1.7 1.8 -2.7 -2.8 0.0 0.6 -1.1 1.3
Body fat percentage 0.7 2.7 4.7 1.5 2.0 -2.2 -2.1 1.8 0.8 -0.9 -1.0
Leg fat percentage (right) 0.4 1.4 3.1 1.1 1.6 -1.3 -1.3 1.8 0.5 -0.8 -0.9
Arm fat-free mass (right) 1.9 9.9 23.4 0.9 3.0 -3.5 -4.2 -0.5 3.2 -4.8 -2.4
Exposure to tobacco smoke outside home 4.0 5.4 12.8 1.4 2.3 -3.6 -3.5 0.7 2.6 -1.6 -1.0
Comparative body size at age 10 0.8 2.1 5.3 2.0 2.3 -1.0 -0.9 2.1 0.6 -0.9 0.2
Number of full brothers 1.1 1.3 4.5 -2.1 -0.7 0.4 0.1 -0.4 -0.5 -1.1 -2.0
Worry too long after embarrassment 0.3 0.5 1.2 -0.2 -1.0 0.9 1.1 0.5 -0.9 -0.0 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 1.5 -1.2 -0.8 0.9 0.8 -0.6 -0.2 1.0 -0.2
Wheeze or whistling in the chest in last year 0.4 0.8 2.5 -1.6 -0.9 -0.2 -0.4 -1.3 -0.7 -0.8 0.2
Number of children fathered 0.2 0.2 0.8 -0.2 -0.5 0.7 0.9 0.2 0.2 -0.1 -0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.5 1.5 -0.5 -0.6 0.9 0.9 0.3 0.2 1.2 -0.7
Age at first live birth 0.3 0.5 1.3 0.7 -0.4 1.1 0.8 -0.5 -0.3 -0.0 1.0
Pulse wave peak to peak time 1.8 2.1 4.5 -1.9 -2.1 1.2 1.2 -1.1 -1.3 1.7 0.5
Health satisfaction 0.4 0.5 1.8 -1.4 -0.8 0.4 0.4 -0.2 -0.6 0.2 -0.7
Shortness of breath walking on level ground 0.8 0.9 2.1 -1.5 -0.9 -0.3 -0.5 -1.5 -1.0 -1.0 0.2
Qualifications: College or University degree 0.2 0.5 1.9 0.8 0.3 0.7 0.6 0.5 -0.6 -0.1 1.4
Eye problems/disorders: None of the above 1.1 1.3 2.5 -1.3 -1.2 0.4 0.2 -1.6 1.2 -1.4 -1.2
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.6 0.7 1.3 -0.8 -1.0 0.1 -0.1 0.2 0.8
Emphysema/chronic bronchitis 1.8 2.1 4.9 -1.8 -0.6 1.5 1.6 0.0 -1.8 2.2 0.1
Medication for pain relief, constipation, heartburn 0.4 0.7 3.2 1.8 1.0 -0.4 -0.2 0.9 0.3 0.1 0.4
Neck or shoulder pain in last month 0.8 1.2 4.6 -1.4 -0.8 0.6 0.3 0.0 0.9 -1.1 -2.2
Medication: Blood pressure 0.2 0.4 0.9 -0.8 1.0 -0.4 -0.6 -0.4 0.6 -0.3 -0.5
Angina (self-reported) 1.3 1.7 6.2 -2.0 -1.5 -0.1 -0.2 -2.5 0.0 -0.8 -0.7
Migraine (self-reported) 0.1 0.1 0.2 0.4 0.3 -0.1 0.1 0.5 0.0 0.3 -0.2
Medication: Ibuprofen 0.4 0.5 1.9 0.2 -0.2 1.0 1.0 1.4 -0.2 0.1 -0.0
Medication: Allopurinol 1.2 1.5 6.0 1.0 2.5 -1.0 -1.4 1.2 0.2 -0.9 0.2
Medication: Omeprazole 0.4 0.5 1.1 -0.9 -0.8 0.8 1.1 0.8 -0.3 0.3 0.0
Medication: Seretide 50 evohaler 0.5 0.6 1.3 1.2 0.6 0.5 0.5 0.9 0.4 0.8 0.9
Mean time to correctly identify matches 0.5 1.0 3.3 -0.8 0.2 -1.1 -1.2 -0.7 1.1 -0.3 -1.8
Heart disease (mother) 0.2 0.3 1.0 -0.0 0.1 1.0 0.9 0.4 0.4 -0.5 0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 1.8 -1.3 -1.1 0.7 0.5 -1.3 -0.4 0.0 -0.5
Whole body fat mass 1.3 5.6 11.0 1.7 2.7 -3.2 -3.3 1.4 1.8 -2.3 -1.7
Leg fat mass (right) 1.0 3.9 7.4 1.0 2.2 -2.5 -2.7 1.1 1.2 -2.4 -1.6
Arm predicted mass (right) 1.9 9.8 23.0 1.0 3.0 -3.5 -4.1 -0.4 3.2 -4.8 -2.4
Pulse rate, automated reading 0.5 1.6 4.7 1.4 2.0 -0.8 -0.7 2.2 0.7 -0.5 -0.1
Alcohol intake frequency. 0.2 0.4 0.7 -0.3 0.4 -0.8 -0.8 0.4 -0.4 -0.7 -0.7
Comparative height size at age 10 1.2 6.7 18.4 2.1 4.3 -3.1 -3.1 2.5 0.9 -1.8 -0.5
Number of full sisters 0.5 0.7 2.8 -0.2 -0.7 -0.8 -0.9 -1.7 0.4 -0.5 -0.1
Suffer from ‘nerves’ 0.1 0.2 0.5 -0.1 0.7 -0.3 -0.2 0.7 -0.7 0.3 -0.2
Overall health rating 0.4 0.9 2.2 0.4 1.5 -1.0 -1.0 1.4 0.2 0.6 -0.6
Chest pain or discomfort 0.6 0.9 2.5 -1.5 -1.6 -0.1 0.1 -1.1 -1.0 0.7 0.1
Had major operations 1.0 1.1 3.5 -0.1 -0.7 1.1 0.9 0.1 -1.5 1.0 1.9
Age at last live birth 0.6 0.9 2.4 0.6 0.0 1.3 1.1 0.2 -0.9 1.0 1.5
Family relationship satisfaction 0.8 1.0 2.1 -1.2 -0.4 1.5 1.5 0.5 -1.3 0.6 0.5
Leg pain on walking 0.1 0.2 0.7 -0.2 -0.9 0.2 0.2 -0.7 -0.0 0.0 -0.4
Qualifications: NVQ or HND or HNC or equivalent 3.0 3.6 7.5 1.2 1.4 -2.1 -2.2 -0.1 2.7 -2.4 -1.8
Commuting to job workplace: Car/motor vehicle 1.5 1.8 4.1 -0.0 -0.4 1.9 2.0 1.3 -1.8 0.5 1.0
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 1.6 -0.6 -0.5 0.5 0.6 -0.1 -1.3 -0.6 0.1
Medication: Aspirin 0.2 0.3 0.8 -0.4 0.1 -0.9 -0.8 -0.6 0.5 0.4 0.1
Supplements: Vitamin C 1.0 1.1 2.6 -1.6 -0.8 1.2 1.0 -1.1 -1.1 1.0 -0.1
Knee pain experienced in last month 0.9 1.4 7.6 -0.7 0.6 0.2 0.2 0.7 1.5 0.0 -2.8
Hypertension (Self-reported) 0.2 0.5 2.2 -1.5 -0.3 -0.1 -0.3 -1.3 -0.3 0.3 -0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.0 1.9 -1.4 -1.3 0.7 0.7 -0.6 -1.2 1.3 0.2
Illnesses of father: Heart disease 2.5 3.5 6.2 2.2 2.5 -2.2 -2.3 1.6 1.6 -1.3 0.0
Illnesses of siblings: Diabetes 0.7 0.9 1.9 -1.2 -0.6 1.4 1.0 -0.7 -1.1 0.3 0.6
Smoking status: Previous 1.3 2.0 4.0 0.6 1.9 -1.7 -2.0 -0.3 1.3 -0.9 -1.5
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 4.6 1.5 2.0 -2.0 -2.1 0.4 0.7 0.1 -0.1
Whole body fat-free mass 1.9 10.6 22.2 1.4 3.2 -4.0 -4.5 -0.3 3.1 -4.7 -2.3
Leg fat-free mass (right) 1.4 7.4 16.4 1.2 2.2 -3.4 -3.9 -0.4 2.5 -4.0 -1.9
Arm fat percentage (left) 0.5 1.9 5.2 1.0 1.3 -2.3 -2.2 0.8 0.5 -0.7 -0.9
Average weekly red wine intake 1.1 1.6 4.3 0.6 1.0 -0.7 -0.7 0.7 1.8 -1.5 -2.1
Handedness (chirality/laterality): Left-handed 0.4 0.5 1.3 -0.8 -0.7 -0.3 -0.4 -0.7 0.6 -0.5 -1.1
Mood swings 0.1 0.3 0.9 -0.3 -0.2 0.2 0.4 0.9 -0.8 0.1 0.4
Loneliness, isolation 0.3 0.5 0.9 -0.5 -0.9 1.0 0.9 0.5 -0.6 0.2 0.4
Long-standing illness, disability or infirmity 0.3 0.4 1.6 -0.0 -0.2 -0.6 -0.1 1.0 -0.6 1.3 0.3
Ever had bowel cancer screening 1.5 1.7 4.1 0.7 0.2 0.5 0.9 1.7 -1.4 1.9 2.0
Diabetes diagnosed by doctor 0.9 1.6 6.5 -0.9 -0.3 -0.3 -0.1 0.1 -2.6 1.1 1.9
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.2 0.4 -0.1 0.5 0.3 0.1 0.6 0.4 0.7 -0.1
Friendships satisfaction 1.1 1.3 3.9 -2.0 -1.3 1.3 1.4 -0.8 -0.7 -0.1 0.3
Qualifications: nursing, teaching 1.1 1.7 3.7 0.1 -1.2 1.3 1.6 0.6 -1.2 1.9 1.7
Commuting to job workplace: Walk 2.9 3.1 9.3 0.2 1.3 -2.9 -3.1 -1.2 1.3 -1.5 -0.4
Eye problems/disorders: Cataract 0.2 0.2 0.4 -0.1 0.6 0.5 0.4 0.6 -0.4 -0.1 -0.3
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.9 -0.3 0.0 -0.1 -0.0 0.3 -1.0 -0.4 -0.2
Medication for cholesterol 0.3 0.4 1.3 0.7 1.0 0.2 0.1 1.1 0.3 -0.7 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.5 1.7 3.6 -0.9 -1.6 1.6 1.7 -0.6 -1.0 1.9 0.3
Back pain experienced in last month 0.5 0.7 1.3 -1.2 0.2 1.2 0.9 0.5 -0.6 1.1 -0.6
Mineral and other dietary supplements 0.8 1.1 2.9 -1.6 -1.2 -0.3 -0.4 -1.7 -0.9 -0.7 0.3
Breast cancer (self-reported) 0.3 0.3 1.1 1.0 -0.1 -0.3 -0.4 -0.6 0.7 0.3 0.7
Asthma (self-reported) 0.3 0.6 1.6 -1.2 -0.4 0.8 0.7 -0.5 -1.1 0.4 0.6
Osteoporosis (self-reported) 0.5 0.7 1.2 -0.3 -0.2 1.0 1.0 0.3 -1.1 0.9 1.0
Osteoarthritis (self-reported) 0.8 1.1 4.0 0.2 0.4 0.1 0.4 1.8 0.3 2.0 -1.1
Medication: Aspirin 0.2 0.2 0.5 -0.4 -0.0 -0.7 -0.6 -0.4 0.3 0.5 0.2
Medication: Gliclazide 2.0 2.2 6.6 -0.4 -0.6 0.9 0.9 -0.4 -2.6 1.9 2.3
Illnesses of father: None of the above (group 1) 2.4 3.0 6.7 -2.6 -2.5 1.6 1.9 -1.3 -1.2 0.8 -1.2
Smoking status: Current 0.6 0.9 2.9 0.7 0.3 -1.0 -0.8 0.0 -1.0 1.1 1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 0.9 0.9 0.4 -0.9 -0.7 0.8 0.3 -0.6 0.7
Whole body water mass 1.9 10.9 22.6 1.5 3.2 -4.0 -4.7 -0.4 3.1 -4.8 -2.2
Leg predicted mass (right) 1.4 7.3 15.7 1.1 2.2 -3.4 -3.8 -0.5 2.5 -4.0 -2.0
Arm fat mass (left) 1.4 5.8 13.5 1.7 2.5 -3.5 -3.7 0.6 1.9 -2.4 -1.4
Number of self-reported non-cancer illnesses 1.4 2.4 5.2 -2.1 -1.6 0.9 1.0 -0.9 -2.3 2.0 0.2
Average weekly champagne plus white wine intake 2.4 3.2 5.7 1.6 2.1 -2.2 -2.4 0.5 1.6 -2.0 -1.2
Miserableness 0.3 0.5 0.9 -0.5 -0.8 0.7 0.8 0.7 -1.0 -0.3 0.3
Guilty feelings 0.3 0.5 1.8 -0.6 -0.4 0.5 0.8 1.3 -0.8 -0.5 -0.3
Wears glasses or contact lenses 0.8 0.9 1.7 -1.3 -0.3 1.0 1.0 0.9 -1.1 1.2 -0.0
Ever taken oral contraceptive pill 0.8 0.9 2.6 0.8 0.2 -1.4 -1.6 -1.0 -0.2 0.2 0.8
Hearing aid user 0.6 0.7 1.7 -0.9 -0.3 1.3 1.3 -0.1 -0.8 0.2 -0.6
Mother’s age at death 0.5 0.7 2.0 0.3 -0.0 1.2 1.1 1.4 -0.1 0.7 0.4
Financial situation satisfaction 1.1 1.3 3.2 -0.1 1.2 -1.4 -1.8 -1.1 1.4 -0.8 -0.2
Tinnitus: Yes, now most or all of the time 2.8 3.2 6.9 0.1 1.7 -1.2 -1.5 1.1 2.5 -2.3 -2.6
Commuting to job workplace: Public transport 2.2 2.6 4.9 0.4 1.1 -1.6 -2.0 -1.4 2.2 -1.6 -1.9
Eye problems/disorders: Glaucoma 1.0 1.1 3.1 1.4 1.8 -1.0 -0.8 1.3 0.7 0.4 -0.1
Medication: Blood pressure 0.2 0.3 0.9 -0.7 -0.6 0.0 0.1 -1.0 0.4 0.6 -0.5
Pain type(s) experienced in last month: Hip pain 1.0 1.2 3.9 0.2 1.0 -0.8 -0.7 0.9 1.1 -1.2 -2.0
Supplements: Fish oil (including cod liver oil) 0.6 0.8 3.2 0.9 0.5 0.8 0.9 1.8 0.2 0.6 -0.6
High cholesterol (Self-reported) 0.8 1.4 3.3 -1.6 -0.9 0.8 1.1 0.8 -1.8 1.4 -0.1
Medication: Bendroflumethiazide 0.4 0.6 1.3 -0.5 0.8 -0.5 -0.8 -1.0 1.1 -0.5 -0.5
Medication: Paracetamol 0.5 0.8 3.3 -1.8 -0.8 0.4 0.4 -0.5 -1.3 -0.4 -0.6
Medication: Lisinopril 0.1 0.1 0.2 0.3 0.4 -0.4 -0.3 0.2 0.1 0.3 0.2
Medication: Atorvastatin 0.6 0.7 2.3 -0.1 1.0 -1.5 -1.5 -0.2 0.6 -0.1 -0.1
Illnesses of father: High blood pressure 1.2 1.5 4.2 2.0 1.2 -0.6 -0.5 1.4 0.1 0.7 1.7
Alcohol drinker status: Never 1.4 1.7 4.1 0.5 1.8 -1.0 -1.2 0.8 0.9 -2.0 -1.5
Ever smoked 0.7 1.2 3.0 0.8 1.5 -1.6 -1.7 -0.4 0.5 -0.7 -0.3
Basal metabolic rate 2.0 10.9 21.7 1.7 3.3 -4.1 -4.7 -0.1 3.0 -4.6 -2.1
Leg fat percentage (left) 0.3 1.1 2.3 0.9 1.3 -1.0 -1.1 1.5 0.5 -0.7 -0.9
Arm fat-free mass (left) 2.3 11.5 23.3 1.8 3.7 -3.9 -4.5 0.3 3.3 -4.8 -2.1
Number of operations (self-reported) 0.4 0.6 2.1 0.6 0.2 0.7 0.6 0.0 -0.5 1.5 1.2
Average weekly beer plus cider intake 0.6 0.8 3.0 -0.0 0.1 -0.3 -0.4 -0.4 -1.7 0.4 1.7
Irritability 0.3 0.5 2.5 -0.8 -0.3 -0.2 -0.0 0.6 -1.6 0.4 -0.1
Risk taking 0.2 0.2 0.9 0.1 0.4 -0.7 -0.4 0.9 -0.4 -0.0 0.3
Ever had prostate specific antigen (PSA) test 0.5 0.6 2.5 0.4 0.2 1.6 1.2 0.2 0.1 0.3 0.6
Fractured/broken bones in last 5 years 1.1 1.4 3.7 -1.4 -1.1 1.3 1.2 -0.4 0.9 -0.5 -1.9
Age started oral contraceptive pill 0.6 0.8 2.0 0.7 -0.1 1.4 1.4 1.1 0.6 -0.6 0.1
Diastolic blood pressure, automated reading 1.2 3.7 9.1 3.0 2.7 -1.4 -1.6 1.3 0.9 -2.0 1.3
Ever depressed for a whole week 0.7 0.9 1.9 -1.4 -1.3 1.1 1.2 -0.2 -1.0 -0.2 0.1
Unable to work because of sickness or disability 0.9 1.1 3.1 -0.2 0.3 -1.8 -1.7 -0.2 -1.5 -0.5 0.7
Commuting to job workplace: Cycle 0.3 0.3 0.5 0.5 -0.5 0.7 0.7 -0.5 0.7 -0.2 0.5
Myopia 0.6 0.8 3.5 0.7 0.5 0.3 0.6 1.9 0.6 1.2 0.1
Vascular/heart problems diagnosed by doctor 0.2 0.6 2.2 1.5 0.3 0.4 0.6 1.5 0.1 -0.4 0.0
Cholesterol lowering medication 0.5 0.8 1.8 -1.4 -0.7 0.6 0.9 1.0 -0.4 1.0 -0.9
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 1.6 -0.9 -0.8 1.0 1.3 0.6 -0.7 0.8 0.5
Pain experienced in last month 0.3 0.5 1.2 -0.1 -0.2 -0.8 -0.7 -1.1 -0.7 -0.6 0.9
Supplements: Calcium 0.2 0.2 0.4 0.2 0.2 -0.6 -0.5 0.1 0.4 0.6 -0.0
Basal cell carcinoma (self-reported) 1.2 1.4 3.8 0.9 0.4 -1.9 -1.9 -0.3 1.4 -1.0 0.1
Heart attack/myocardial infarction (self-reported) 0.2 0.2 0.5 -0.5 -0.2 -0.7 -0.7 -0.2 -0.1 -0.4 0.5
Deep venous thrombosis (DVT) (self-reported) 3.8 4.8 9.2 2.0 2.9 -3.0 -2.8 2.1 1.7 -1.0 -1.1
Heart disease (siblings) 0.5 0.6 1.2 -0.9 -1.1 1.0 0.9 -0.4 0.1 0.7 -0.6
Alcohol drinker status: Previous 1.4 1.6 3.2 -1.8 -1.6 0.9 1.1 -0.6 -1.2 1.6 -0.6
Pack years of smoking 0.3 0.4 1.8 0.4 0.8 -0.2 0.1 1.4 0.8 0.2 -0.1
Impedance of whole body 0.7 3.4 12.8 0.1 -1.0 1.7 2.1 0.9 -2.0 3.6 1.3
Leg fat mass (left) 0.9 3.5 6.5 0.9 2.1 -2.4 -2.5 1.1 1.2 -2.3 -1.7
Arm predicted mass (left) 2.4 12.4 26.2 1.7 3.7 -4.2 -4.8 -0.1 3.4 -5.1 -2.1