Best TWAS P=1.52e-22 · Best GWAS P=1.1e-39 conditioned to NaN
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | C14orf39 | 0.08 | 0.05 | lasso | 8 | 0.06 | 2.1e-05 | 6.577 | -6.7 | 2.1e-11 | -0.41 | 0.92 | 0.01 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | RP11-193F5.4 | 0.06 | 0.00 | enet | 16 | 0.01 | 6.5e-02 | 6.791 | 5.6 | 1.9e-08 | 0.33 | 0.11 | 0.11 | FALSE |
3 | GTEx | Esophagus Muscularis | C14orf39 | 0.10 | 0.02 | enet | 9 | 0.02 | 2.9e-02 | 0.096 | -5.1 | 2.6e-07 | -0.41 | 0.12 | 0.16 | TRUE |
4 | GTEx | Liver | MNAT1 | 0.21 | 0.00 | lasso | 4 | -0.01 | 5.4e-01 | 0.774 | -7.3 | 2.1e-13 | -0.44 | 0.08 | 0.19 | TRUE |
5 | GTEx | Muscle Skeletal | C14orf39 | 0.06 | 0.05 | lasso | 3 | 0.05 | 2.7e-05 | 6.577 | -9.8 | 1.5e-22 | -0.67 | 0.16 | 0.82 | TRUE |
6 | GTEx | Pituitary | C14orf39 | 0.39 | 0.38 | enet | 20 | 0.35 | 1.0e-09 | 6.577 | -5.5 | 3.8e-08 | -0.34 | 0.98 | 0.00 | TRUE |
7 | GTEx | Skin Not Sun Exposed Suprapubic | PCNXL4 | 0.15 | 0.05 | enet | 15 | 0.12 | 6.2e-07 | 2.650 | -9.0 | 1.5e-19 | -0.61 | 0.75 | 0.12 | TRUE |
8 | The Cancer Genome Atlas | Lung Adenocarcinoma | C14orf39 | 0.02 | 0.02 | blup | 37 | 0.02 | 4.2e-03 | 6.387 | -9.0 | 2.4e-19 | -0.55 | 0.07 | 0.37 | FALSE |
9 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C14orf39 | 0.08 | 0.05 | blup | 37 | 0.05 | 4.2e-03 | 6.406 | -8.5 | 1.3e-17 | -0.51 | 0.08 | 0.44 | FALSE |
10 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf39 | 0.08 | 0.09 | blup | 37 | 0.11 | 1.8e-11 | 6.769 | -8.4 | 5.1e-17 | -0.51 | 1.00 | 0.00 | FALSE |