[Hub]/) : Traits : Arm predicted mass (left) :

chr14:72,695,406-74,627,634

Best TWAS P=1.07e-10 · Best GWAS P=1.59e-09 conditioned to 0.002

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DCAF4 0.23 0.07 enet 30 0.13 4.3e-07 4.7 6.0 2.5e-09 0.48 0.16 0.82 FALSE
2 GTEx Breast Mammary Tissue DCAF4 0.24 0.10 lasso 6 0.18 1.2e-09 4.8 5.3 9.1e-08 0.54 0.31 0.67 FALSE
3 GTEx Colon Sigmoid DCAF4 0.30 0.10 lasso 9 0.11 1.3e-04 5.4 6.4 1.8e-10 0.74 0.01 0.93 FALSE
4 GTEx Colon Transverse DCAF4 0.26 0.27 lasso 10 0.27 2.7e-13 4.8 5.2 1.6e-07 0.54 0.40 0.60 FALSE
5 GTEx Esophagus Gastroesophageal Junction DCAF4 0.18 0.01 enet 10 0.06 3.0e-03 5.4 6.5 1.1e-10 0.53 0.07 0.50 TRUE
6 GTEx Esophagus Mucosa ZFYVE1 0.10 0.00 lasso 7 0.00 2.0e-01 5.4 6.2 7.3e-10 0.61 0.10 0.67 FALSE
7 GTEx Pancreas DCAF4 0.20 0.15 lasso 4 0.14 2.4e-06 5.4 5.4 8.7e-08 0.60 0.06 0.88 FALSE
8 GTEx Spleen DCAF4 0.47 0.12 enet 10 0.19 1.5e-05 4.8 6.2 7.5e-10 0.63 0.11 0.84 FALSE
9 GTEx Spleen NUMB 0.46 -0.01 enet 28 0.09 3.2e-03 1.4 5.6 2.7e-08 0.48 0.08 0.27 FALSE
10 NTR Blood DCAF4 0.04 0.03 lasso 6 0.03 6.5e-09 5.4 5.5 3.9e-08 0.60 0.06 0.94 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DCAF4 0.04 0.02 blup 83 0.03 1.2e-04 4.4 5.2 1.7e-07 0.55 0.02 0.95 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPF3 0.18 0.18 lasso 7 0.22 1.6e-24 5.0 5.7 1.0e-08 0.91 0.00 1.00 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma DPF3 0.10 0.02 blup 210 0.07 1.9e-07 -3.0 -5.6 2.0e-08 -0.53 0.76 0.18 FALSE