[Hub]/) : Traits : Arm predicted mass (left) :

chr16:52,772,129-54,846,383

Best TWAS P=3.14e-33 · Best GWAS P=3.29e-116 conditioned to 2.14e-51

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FTO 0.11 0.00 bslmm 739 0.02 1.6e-03 0.47 11.9 7.7e-33 0.38 0.09 0.55 TRUE
2 CommonMind Brain Pre-frontal Cortex RBL2 0.22 0.24 enet 15 0.26 1.8e-31 4.76 -6.0 2.1e-09 0.02 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous RBL2 0.34 0.28 enet 18 0.30 1.0e-24 4.83 -5.6 2.7e-08 0.02 1.00 0.00 FALSE
4 GTEx Artery Tibial RBL2 0.16 0.17 enet 11 0.20 2.1e-15 4.84 -5.9 4.8e-09 0.02 1.00 0.00 FALSE
5 GTEx Brain Cerebellar Hemisphere RBL2 0.55 0.55 enet 20 0.46 2.1e-13 4.83 -5.3 1.4e-07 0.04 1.00 0.00 FALSE
6 GTEx Brain Cortex RBL2 0.51 0.45 enet 12 0.46 3.5e-14 4.20 -5.8 5.8e-09 0.02 1.00 0.00 FALSE
7 GTEx Colon Sigmoid RBL2 0.38 0.37 lasso 12 0.29 8.4e-11 4.83 -5.5 3.9e-08 0.03 1.00 0.00 FALSE
8 GTEx Esophagus Mucosa RBL2 0.36 0.36 enet 37 0.37 2.9e-26 4.83 -5.4 5.7e-08 0.00 1.00 0.00 FALSE
9 GTEx Heart Left Ventricle RBL2 0.12 0.11 enet 12 0.08 3.3e-05 4.75 -5.2 2.2e-07 -0.03 0.94 0.01 FALSE
10 GTEx Lung RBL2 0.29 0.37 enet 16 0.35 9.1e-28 4.83 -5.2 2.2e-07 0.03 1.00 0.00 FALSE
11 GTEx Muscle Skeletal RBL2 0.11 0.00 lasso 5 0.00 2.9e-01 6.38 -9.1 1.2e-19 -0.10 0.28 0.23 FALSE
12 GTEx Nerve Tibial RBL2 0.46 0.52 enet 19 0.53 1.6e-43 4.76 -5.2 2.3e-07 0.04 1.00 0.00 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic RBL2 0.35 0.33 enet 16 0.34 2.6e-19 4.77 -5.2 1.8e-07 0.03 1.00 0.00 FALSE
14 GTEx Skin Sun Exposed Lower leg RBL2 0.35 0.39 enet 25 0.37 2.9e-32 4.77 -5.2 1.7e-07 0.03 1.00 0.00 FALSE
15 GTEx Spleen RBL2 0.59 0.47 enet 51 0.46 3.2e-13 4.87 -6.1 8.2e-10 -0.06 1.00 0.00 FALSE
16 GTEx Testis AKTIP 0.19 0.00 enet 26 0.00 1.9e-01 4.20 12.0 3.1e-33 0.51 0.03 0.40 TRUE
17 GTEx Vagina RBL2 0.41 0.37 enet 13 0.34 1.6e-08 5.15 -5.3 9.1e-08 0.03 0.89 0.01 FALSE
18 YFS Blood AKTIP 0.19 0.27 lasso 13 0.30 3.3e-99 7.11 6.4 1.6e-10 -0.01 1.00 0.00 FALSE
19 The Cancer Genome Atlas Esophageal Carcinoma RBL2 0.08 0.04 lasso 3 0.03 4.4e-02 7.11 5.9 3.9e-09 0.00 0.01 0.82 FALSE
20 The Cancer Genome Atlas Glioblastoma Multiforme FTO 0.27 0.16 enet 13 0.14 6.7e-05 -2.32 8.9 6.0e-19 0.33 0.11 0.32 TRUE
21 The Cancer Genome Atlas Brain Lower Grade Glioma RBL2 0.03 0.06 enet 5 0.05 8.2e-07 4.20 -5.3 1.2e-07 0.04 0.81 0.18 FALSE
22 The Cancer Genome Atlas Pancreatic Adenocarcinoma RBL2 0.11 0.08 blup 44 0.06 1.5e-03 6.40 -6.1 8.8e-10 -0.03 0.01 0.78 FALSE