[Hub]/) : Traits : Arm predicted mass (left) :

chr1:182,298,784-184,739,300

Best TWAS P=6.11e-14 · Best GWAS P=2.58e-14 conditioned to 0.858

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TSEN15 0.23 0.18 lasso 9 0.18 4.7e-21 7.1 7.0 1.9e-12 0.90 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum RP11-181K3.4 0.13 0.06 lasso 3 0.14 8.3e-08 5.0 5.5 3.6e-08 0.04 0.04 0.95 TRUE
3 GTEx Brain Cerebellar Hemisphere TSEN15 0.38 0.08 lasso 13 0.16 5.3e-05 7.2 6.6 3.9e-11 0.83 0.01 0.96 TRUE
4 GTEx Brain Cerebellum COLGALT2 0.49 0.05 lasso 8 0.10 9.2e-04 4.6 -5.1 2.9e-07 -0.39 0.10 0.17 FALSE
5 GTEx Esophagus Muscularis RP11-181K3.4 0.05 0.09 lasso 1 0.07 3.9e-05 5.2 5.2 2.1e-07 0.03 0.04 0.94 FALSE
6 GTEx Nerve Tibial LAMC1 0.07 0.08 enet 30 0.05 1.1e-04 5.3 5.3 1.3e-07 0.07 0.03 0.96 FALSE
7 METSIM Adipose TSEN15 0.06 0.02 enet 28 0.04 1.3e-06 7.1 6.2 4.9e-10 0.76 0.02 0.98 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GLT25D2 0.05 0.01 enet 10 0.04 6.3e-05 4.7 -7.5 6.1e-14 -0.69 0.01 0.94 TRUE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GLT25D2 0.11 0.02 blup 119 0.05 5.1e-06 -1.8 -5.5 3.4e-08 -0.50 0.14 0.31 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma TSEN15 0.11 0.08 blup 52 0.10 6.7e-12 7.2 5.9 3.0e-09 0.78 0.02 0.98 FALSE