[Hub]/) : Traits : Arm predicted mass (left) :

chr2:206,284,251-209,182,548

Best TWAS P=4.02e-10 · Best GWAS P=9.19e-09 conditioned to 0.0032

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous METTL21A 0.10 0.02 lasso 4 0.02 1.6e-02 -4.6 5.3 1.5e-07 0.32 0.18 0.23 FALSE
2 GTEx Brain Putamen basal ganglia NDUFS1 0.16 0.06 enet 6 0.05 2.9e-02 -4.2 5.2 2.0e-07 0.03 0.04 0.61 FALSE
3 GTEx Cells Transformed fibroblasts CREB1 0.15 0.00 enet 7 0.00 2.8e-01 -4.7 -6.2 4.0e-10 -0.50 0.14 0.41 TRUE
4 GTEx Esophagus Gastroesophageal Junction NDUFS1 0.16 0.09 enet 22 0.03 2.4e-02 -4.5 5.2 2.3e-07 0.01 0.03 0.92 FALSE
5 GTEx Esophagus Mucosa METTL21A 0.10 0.10 enet 9 0.12 1.8e-08 -4.6 5.2 2.6e-07 0.57 0.40 0.58 FALSE
6 GTEx Nerve Tibial AC007383.4 0.14 0.06 lasso 6 0.05 3.0e-04 -4.8 5.3 1.4e-07 0.01 0.03 0.96 TRUE
7 GTEx Testis NDUFS1 0.15 0.08 lasso 6 0.08 2.1e-04 -4.6 5.2 2.6e-07 0.02 0.05 0.84 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma CREB1 0.03 0.01 blup 64 0.01 2.5e-02 -5.1 -5.2 2.4e-07 -0.49 0.09 0.53 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma FAM119A 0.04 0.02 blup 51 0.03 1.0e-06 -4.5 5.2 1.5e-07 0.64 0.03 0.95 FALSE