[Hub]/) : Traits : Arm predicted mass (left) :

chr1:25,488,741-27,488,299

Best TWAS P=2.88e-11 · Best GWAS P=2.33e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts RP1-125I3.2 0.06 0.04 enet 19 0.03 3.3e-03 5.3 -5.8 8.0e-09 -0.48 0.09 0.42 FALSE
2 GTEx Esophagus Mucosa DHDDS 0.11 0.06 lasso 4 0.04 6.6e-04 -4.7 -5.1 3.0e-07 -0.20 0.57 0.02 FALSE
3 GTEx Esophagus Mucosa PDIK1L 0.10 0.09 lasso 6 0.09 8.8e-07 6.5 -6.4 1.6e-10 -0.97 0.02 0.98 FALSE
4 GTEx Pancreas CNKSR1 0.20 0.03 enet 20 0.04 7.3e-03 4.7 -5.7 1.0e-08 -0.56 0.08 0.42 FALSE
5 GTEx Thyroid DHDDS 0.14 0.08 enet 22 0.07 5.8e-06 6.1 -5.9 4.2e-09 -0.12 0.18 0.74 TRUE
6 GTEx Thyroid CNKSR1 0.10 0.04 lasso 7 0.03 2.1e-03 5.2 -5.7 1.6e-08 -0.71 0.10 0.89 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma TRIM63 0.03 0.02 blup 33 0.02 4.6e-03 6.7 6.2 5.8e-10 0.93 0.01 0.90 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma PDIK1L 0.02 0.01 blup 37 0.02 6.1e-05 6.6 -5.2 2.4e-07 -0.88 0.02 0.94 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma TRIM63 0.15 0.16 lasso 2 0.16 2.3e-32 6.7 6.7 2.9e-11 1.00 0.00 1.00 TRUE
10 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma TRIM63 0.14 0.15 lasso 1 0.14 2.2e-07 6.5 6.5 8.8e-11 0.98 0.01 0.99 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma TRIM63 0.08 0.10 lasso 4 0.10 3.7e-06 6.6 6.2 7.9e-10 0.97 0.01 0.99 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDIK1L 0.02 0.02 blup 37 0.02 2.8e-03 6.6 -6.5 6.5e-11 -0.95 0.01 0.85 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIM63 0.11 0.11 enet 4 0.12 9.0e-14 6.6 5.9 4.3e-09 0.97 0.00 1.00 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma PDIK1L 0.03 0.01 blup 37 0.02 2.6e-03 5.4 -6.4 1.5e-10 -0.86 0.01 0.59 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma TRIM63 0.29 0.33 enet 20 0.33 2.5e-38 6.6 6.6 3.9e-11 0.95 0.00 1.00 FALSE
16 The Cancer Genome Atlas Lung Adenocarcinoma TRIM63 0.14 0.20 enet 7 0.21 9.4e-24 6.3 6.0 2.3e-09 0.97 0.01 0.99 FALSE
17 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PDIK1L 0.02 0.00 blup 37 0.02 1.2e-03 2.8 -5.4 6.0e-08 -0.90 0.02 0.75 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TRIM63 0.16 0.11 lasso 1 0.10 2.0e-11 6.6 6.6 5.0e-11 0.98 0.00 1.00 FALSE
19 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TRIM63 0.14 0.18 lasso 7 0.15 3.0e-10 6.2 6.0 1.9e-09 0.97 0.02 0.98 FALSE
20 The Cancer Genome Atlas Prostate Adenocarcinoma SH3BGRL3 0.05 0.03 lasso 2 0.03 9.3e-04 5.3 5.7 1.2e-08 0.53 0.00 0.95 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma TRIM63 0.18 0.26 enet 7 0.26 3.0e-25 6.3 6.2 7.4e-10 0.97 0.01 0.99 FALSE
22 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma TRIM63 0.19 0.07 blup 33 0.14 1.3e-04 6.6 5.5 4.1e-08 0.91 0.01 0.99 FALSE