[Hub]/) : Traits : Arm predicted mass (left) :

chr3:51,860,817-53,860,103

Best TWAS P=1.2e-09 · Best GWAS P=2.7e-08 conditioned to 0.758

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NT5DC2 0.11 0.05 enet 22 0.04 5.0e-06 3.2 -5.1 2.9e-07 -0.47 0.19 0.75 FALSE
2 GTEx Pancreas RFT1 0.32 0.13 lasso 4 0.17 1.3e-07 5.6 5.2 1.7e-07 0.93 0.00 1.00 FALSE
3 GTEx Prostate RFT1 0.39 0.18 enet 17 0.24 1.1e-06 3.2 5.2 1.5e-07 0.68 0.09 0.84 TRUE
4 GTEx Stomach RFT1 0.23 0.03 enet 19 0.06 6.3e-04 3.2 5.2 1.7e-07 0.75 0.08 0.84 FALSE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma RFT1 0.18 0.10 lasso 7 0.10 1.8e-08 5.0 5.3 1.2e-07 0.97 0.00 0.99 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMEM110 0.19 0.13 blup 59 0.13 4.2e-11 4.4 5.2 1.7e-07 0.84 0.10 0.89 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma RFT1 0.10 0.08 enet 11 0.15 2.3e-29 4.8 5.1 2.7e-07 0.80 0.03 0.96 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma RFT1 0.10 0.05 enet 12 0.05 1.0e-03 5.1 5.2 1.9e-07 0.87 0.01 0.91 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM110 0.13 0.06 blup 59 0.08 3.3e-09 3.4 5.2 2.0e-07 0.67 0.71 0.20 FALSE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RFT1 0.31 0.07 blup 45 0.19 1.8e-09 2.8 5.8 6.9e-09 0.86 0.02 0.97 FALSE
11 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SFMBT1 0.17 0.08 lasso 2 0.06 5.5e-04 5.1 5.1 2.9e-07 0.97 0.02 0.93 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma RFT1 0.14 0.11 blup 45 0.11 1.9e-12 4.8 5.3 1.4e-07 0.92 0.01 0.99 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma SPCS1 0.11 0.00 blup 41 0.01 9.9e-03 -3.5 6.1 1.2e-09 0.36 0.00 0.02 TRUE
14 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RFT1 0.07 0.03 enet 7 0.06 1.2e-07 4.7 5.2 1.7e-07 0.75 0.01 0.98 FALSE
15 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMEM110 0.20 0.13 blup 59 0.15 3.0e-10 5.4 5.3 9.5e-08 0.82 0.01 0.99 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM110 0.20 0.06 blup 59 0.10 1.2e-10 5.4 5.3 1.3e-07 0.83 0.01 0.99 FALSE
17 The Cancer Genome Atlas Soft Tissue Sarcoma RFT1 0.16 0.12 enet 16 0.14 1.7e-08 5.0 5.2 2.1e-07 0.90 0.01 0.99 FALSE
18 The Cancer Genome Atlas Soft Tissue Sarcoma TMEM110 0.12 0.07 blup 59 0.12 7.5e-08 5.2 5.2 2.0e-07 0.73 0.02 0.97 FALSE
19 The Cancer Genome Atlas Skin Cutaneous Melanoma RFT1 0.29 0.04 blup 45 0.11 8.2e-04 4.8 5.5 3.9e-08 0.79 0.01 0.81 FALSE
20 The Cancer Genome Atlas Stomach Adenocarcinoma RFT1 0.13 0.05 blup 45 0.10 6.9e-08 5.1 5.8 5.7e-09 0.85 0.01 0.98 FALSE
21 The Cancer Genome Atlas Testicular Germ Cell Tumors RFT1 0.39 0.22 lasso 4 0.25 3.1e-09 4.9 5.1 2.8e-07 0.94 0.01 0.99 FALSE
22 The Cancer Genome Atlas Testicular Germ Cell Tumors TMEM110 0.20 0.01 lasso 2 0.09 3.2e-04 5.4 5.4 8.1e-08 0.97 0.00 0.85 FALSE
23 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RFT1 0.29 0.15 blup 45 0.15 6.5e-05 4.7 6.0 1.4e-09 0.85 0.01 0.84 FALSE