Best TWAS P=8.96e-09 · Best GWAS P=4.33e-08 conditioned to 0.24
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | RP11-810M2.2 | 0.30 | 0.02 | lasso | 4 | 0.02 | 8.5e-02 | 5.4 | 5.7 | 9.0e-09 | 0.91 | 0.01 | 0.83 | TRUE |
| 2 | GTEx | Brain Putamen basal ganglia | AC012146.7 | 0.30 | 0.03 | enet | 23 | 0.03 | 7.6e-02 | 3.4 | -5.2 | 1.8e-07 | 0.05 | 0.03 | 0.09 | TRUE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | GP1BA | 0.35 | 0.16 | lasso | 11 | 0.18 | 5.9e-07 | 3.8 | 5.1 | 2.7e-07 | -0.02 | 0.07 | 0.64 | FALSE |
| 4 | GTEx | Muscle Skeletal | ZZEF1 | 0.11 | 0.01 | lasso | 3 | 0.01 | 1.9e-02 | 5.1 | 5.2 | 2.2e-07 | 0.95 | 0.02 | 0.95 | FALSE |