Best TWAS P=4.21e-08 · Best GWAS P=1.56e-07 conditioned to 1.4e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | TNFSF12 | 0.06 | 0.07 | bslmm | 462 | 0.07 | 9.4e-23 | 5.0 | 5.5 | 4.2e-08 | 0.00 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | CHRNB1 | 0.03 | 0.02 | blup | 57 | 0.02 | 7.8e-04 | -3.8 | -5.4 | 6.2e-08 | -0.05 | 0.01 | 0.87 | FALSE |