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chr19:32,209,988-34,959,979

Best TWAS P=7.3e-23 · Best GWAS P=7.11e-20 conditioned to 0.624

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DPY19L3	0.07	0.05	lasso	2	0.06	8.7e-08	-5.7	-5.4	6.9e-08	-0.01	0.00	1.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	PEPD	0.32	0.27	enet	22	0.38	1.2e-49	2.4	6.2	4.2e-10	0.48	1.00	0.00	FALSE
3	GTEx	Breast Mammary Tissue	PEPD	0.16	0.06	lasso	4	0.04	3.5e-03	5.7	6.6	5.6e-11	0.78	0.45	0.50	FALSE
4	GTEx	Colon Transverse	PEPD	0.14	0.16	lasso	2	0.13	1.2e-06	5.7	5.6	1.8e-08	0.71	0.66	0.19	FALSE
5	GTEx	Esophagus Mucosa	PEPD	0.37	0.32	enet	20	0.39	9.5e-28	5.7	8.1	5.9e-16	0.87	0.02	0.98	FALSE
6	GTEx	Muscle Skeletal	PEPD	0.08	0.03	lasso	4	0.04	1.3e-04	-6.9	5.4	8.4e-08	0.51	0.51	0.23	FALSE
7	GTEx	Skin Sun Exposed Lower leg	CEBPG	0.16	0.08	enet	11	0.14	6.1e-12	-5.3	5.3	1.0e-07	0.29	1.00	0.00	FALSE
8	METSIM	Adipose	CHST8	0.22	0.17	lasso	4	0.17	3.7e-25	5.7	5.8	5.0e-09	0.73	1.00	0.00	FALSE
9	METSIM	Adipose	PEPD	0.19	0.18	lasso	5	0.17	2.3e-24	5.7	5.8	8.2e-09	0.73	1.00	0.00	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PEPD	0.06	0.01	blup	114	0.04	2.6e-04	9.1	7.8	5.8e-15	0.84	0.01	0.95	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	PEPD	0.13	0.06	blup	113	0.10	1.2e-06	5.0	9.8	7.3e-23	0.86	0.02	0.98	TRUE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PEPD	0.04	0.05	blup	113	0.03	1.9e-04	-6.9	6.3	2.3e-10	0.53	0.56	0.16	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	PEPD	0.05	0.03	blup	113	0.05	7.1e-07	7.0	5.7	9.0e-09	0.69	0.07	0.92	FALSE
14	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PEPD	0.16	0.07	lasso	3	0.05	3.1e-03	9.1	8.7	2.2e-18	0.95	0.01	0.96	FALSE
15	The Cancer Genome Atlas	Prostate Adenocarcinoma	PEPD	0.08	0.04	lasso	8	0.03	2.8e-04	6.8	5.8	8.1e-09	0.32	0.29	0.03	TRUE