[Hub]/) : Traits : Trunk fat percentage :

chr20:24,230,055-26,307,797

Best TWAS P=1.92e-15 · Best GWAS P=2.46e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ABHD12 0.10 0.17 blup 405 0.17 1.7e-20 7.1 7.9 2.3e-15 0.91 0.08 0.92 FALSE
2 CommonMind Brain Pre-frontal Cortex NINL 0.19 0.17 lasso 20 0.23 1.2e-27 7.2 7.9 1.9e-15 0.86 0.07 0.93 TRUE
3 CommonMind Brain Pre-frontal Cortex PYGB 0.10 0.05 lasso 3 0.05 6.9e-07 5.1 -5.5 3.5e-08 -0.33 0.90 0.01 FALSE
4 GTEx Adipose Visceral Omentum ABHD12 0.06 0.00 lasso 8 0.00 4.6e-01 7.2 7.3 3.7e-13 0.88 0.08 0.69 FALSE
5 GTEx Artery Aorta ABHD12 0.06 0.03 enet 6 0.03 5.4e-03 6.9 6.5 8.7e-11 0.90 0.08 0.87 FALSE
6 GTEx Artery Aorta NINL 0.17 0.18 lasso 6 0.19 1.5e-10 7.2 7.6 3.4e-14 0.95 0.06 0.94 FALSE
7 GTEx Artery Tibial ABHD12 0.12 0.12 enet 25 0.15 7.1e-12 6.7 6.8 8.0e-12 0.91 0.13 0.87 FALSE
8 GTEx Artery Tibial ENTPD6 0.24 0.12 lasso 9 0.17 2.1e-13 6.1 -5.9 4.2e-09 -0.75 0.27 0.73 FALSE
9 GTEx Brain Caudate basal ganglia ABHD12 0.09 0.05 enet 13 0.04 2.9e-02 7.2 7.2 4.6e-13 0.96 0.08 0.77 FALSE
10 GTEx Brain Cerebellar Hemisphere PYGB 0.20 0.16 lasso 5 0.12 5.8e-04 6.5 -6.4 1.6e-10 -0.88 0.08 0.75 FALSE
11 GTEx Brain Cerebellar Hemisphere NINL 0.17 0.07 enet 18 0.11 1.1e-03 6.9 6.1 1.3e-09 0.77 0.07 0.71 FALSE
12 GTEx Brain Cerebellar Hemisphere ENTPD6 0.22 0.26 lasso 3 0.17 3.8e-05 6.5 -6.4 1.3e-10 -0.94 0.12 0.86 FALSE
13 GTEx Brain Cerebellum ENTPD6 0.15 0.23 enet 8 0.14 4.6e-05 5.6 -5.9 3.9e-09 -0.88 0.18 0.78 TRUE
14 GTEx Brain Cortex ABHD12 0.08 0.11 lasso 8 0.09 1.4e-03 7.2 7.0 2.3e-12 0.94 0.06 0.77 FALSE
15 GTEx Breast Mammary Tissue CST7 0.10 0.00 lasso 4 0.00 7.3e-01 -4.9 5.7 1.0e-08 0.79 0.07 0.68 FALSE
16 GTEx Breast Mammary Tissue ABHD12 0.08 0.09 lasso 5 0.09 3.3e-05 7.2 7.3 2.1e-13 0.92 0.08 0.89 FALSE
17 GTEx Breast Mammary Tissue (Male) ABHD12 0.06 0.01 lasso 3 0.02 1.3e-01 6.0 6.6 3.5e-11 0.70 0.05 0.17 FALSE
18 GTEx Cells EBV-transformed lymphocytes PYGB 0.38 0.08 lasso 5 0.06 7.0e-03 5.9 5.8 5.6e-09 0.75 0.10 0.78 TRUE
19 GTEx Cells Transformed fibroblasts ABHD12 0.24 0.33 lasso 4 0.35 6.3e-27 7.2 7.4 2.0e-13 0.98 0.05 0.95 FALSE
20 GTEx Cells Transformed fibroblasts GINS1 0.04 0.01 lasso 3 0.01 5.2e-02 2.6 5.2 2.1e-07 0.83 0.12 0.80 FALSE
21 GTEx Colon Sigmoid ABHD12 0.17 0.17 lasso 15 0.17 1.0e-06 6.6 6.8 1.3e-11 0.90 0.10 0.89 TRUE
22 GTEx Esophagus Gastroesophageal Junction ABHD12 0.15 0.14 lasso 13 0.14 7.0e-06 6.5 6.4 1.3e-10 0.96 0.07 0.93 FALSE
23 GTEx Esophagus Mucosa ENTPD6 0.09 0.04 enet 20 0.06 4.2e-05 7.1 -6.1 1.2e-09 -0.87 0.09 0.91 FALSE
24 GTEx Esophagus Muscularis ABHD12 0.10 0.10 enet 42 0.09 4.5e-06 7.1 5.9 2.7e-09 0.87 0.07 0.92 FALSE
25 GTEx Esophagus Muscularis ENTPD6 0.16 0.03 lasso 5 0.05 7.3e-04 5.0 -5.7 1.2e-08 -0.81 0.12 0.56 FALSE
26 GTEx Heart Atrial Appendage ABHD12 0.07 0.06 enet 16 0.06 1.0e-03 7.1 7.1 1.6e-12 0.97 0.07 0.92 FALSE
27 GTEx Heart Left Ventricle ABHD12 0.15 0.14 lasso 10 0.12 4.0e-07 7.3 7.5 5.2e-14 0.99 0.06 0.94 FALSE
28 GTEx Heart Left Ventricle NINL 0.08 0.03 enet 11 0.05 1.1e-03 6.7 6.5 9.3e-11 0.74 0.25 0.60 FALSE
29 GTEx Liver ABHD12 0.20 0.20 lasso 19 0.15 7.3e-05 7.1 7.0 1.8e-12 0.97 0.08 0.92 FALSE
30 GTEx Liver APMAP 0.20 -0.01 lasso 9 0.00 3.8e-01 7.1 5.6 2.1e-08 0.67 0.07 0.63 TRUE
31 GTEx Lung ABHD12 0.06 0.00 lasso 6 0.00 2.7e-01 6.1 7.0 3.3e-12 0.67 0.12 0.64 FALSE
32 GTEx Lung NINL 0.07 0.05 lasso 4 0.04 5.3e-04 -5.3 -6.5 6.4e-11 -0.86 0.08 0.91 FALSE
33 GTEx Muscle Skeletal ENTPD6 0.04 0.02 lasso 4 0.01 1.5e-02 5.9 -6.3 3.1e-10 -0.90 0.09 0.85 FALSE
34 GTEx Nerve Tibial PYGB 0.26 0.15 enet 11 0.14 5.7e-10 5.7 -6.2 7.6e-10 -0.64 0.97 0.03 FALSE
35 GTEx Nerve Tibial ABHD12 0.24 0.44 lasso 11 0.44 5.1e-34 7.2 -7.0 2.9e-12 -0.98 0.07 0.93 FALSE
36 GTEx Ovary ABHD12 0.23 0.04 lasso 8 0.05 1.9e-02 7.1 5.8 8.2e-09 0.87 0.07 0.68 FALSE
37 GTEx Pancreas ENTPD6 0.11 0.05 enet 23 0.05 5.0e-03 6.1 -7.1 1.1e-12 -0.77 0.09 0.85 FALSE
38 GTEx Pituitary ABHD12 0.27 0.31 enet 25 0.31 1.8e-08 7.1 7.6 2.5e-14 0.92 0.08 0.92 FALSE
39 GTEx Skin Not Sun Exposed Suprapubic PYGB 0.12 0.13 enet 13 0.14 4.2e-08 5.3 -5.7 1.1e-08 -0.53 0.56 0.28 FALSE
40 GTEx Skin Not Sun Exposed Suprapubic ENTPD6 0.12 0.09 lasso 2 0.07 1.1e-04 5.7 -5.7 1.0e-08 -0.64 0.18 0.44 FALSE
41 GTEx Skin Sun Exposed Lower leg PYGB 0.11 0.10 lasso 4 0.09 1.2e-07 5.0 -5.4 6.4e-08 -0.59 0.87 0.12 FALSE
42 GTEx Skin Sun Exposed Lower leg ABHD12 0.07 0.03 lasso 10 0.05 7.3e-05 5.6 7.0 1.9e-12 0.92 0.12 0.87 FALSE
43 GTEx Spleen PYGB 0.15 0.09 lasso 6 0.04 2.6e-02 7.1 6.6 4.2e-11 0.95 0.08 0.83 FALSE
44 GTEx Testis ABHD12 0.21 0.18 enet 25 0.23 1.1e-10 7.2 7.3 2.3e-13 0.92 0.06 0.94 FALSE
45 GTEx Thyroid PYGB 0.10 0.09 lasso 2 0.09 4.4e-07 5.7 -5.6 2.7e-08 -0.57 0.89 0.09 TRUE
46 GTEx Thyroid ABHD12 0.05 0.04 lasso 5 0.03 3.9e-03 7.1 -7.1 1.5e-12 -0.98 0.08 0.90 FALSE
47 GTEx Thyroid NINL 0.13 0.18 enet 17 0.20 6.2e-15 -4.7 -7.1 1.8e-12 -0.84 0.34 0.66 FALSE
48 GTEx Thyroid VN1R108P 0.05 0.01 lasso 2 0.02 1.8e-02 2.8 5.5 3.4e-08 0.86 0.08 0.77 FALSE
49 GTEx Whole Blood PYGB 0.17 0.14 enet 22 0.18 2.7e-16 7.1 5.5 4.8e-08 0.90 0.09 0.91 FALSE
50 NTR Blood PYGB 0.07 0.10 enet 22 0.12 3.6e-36 7.2 5.6 1.8e-08 0.93 0.06 0.94 FALSE
51 ROSMAP Brain Pre-frontal Cortex PYGB 0.20 0.10 bslmm 414 0.11 3.2e-14 6.0 -7.1 1.5e-12 -0.65 0.55 0.46 FALSE
52 ROSMAP Brain Pre-frontal Cortex ABHD12 0.26 0.35 enet 35 0.42 7.9e-58 6.7 6.8 8.2e-12 0.86 0.10 0.90 FALSE
53 ROSMAP Brain Pre-frontal Cortex NINL 0.19 0.19 enet 18 0.25 2.1e-32 7.1 6.6 3.9e-11 0.86 0.07 0.93 FALSE
54 ROSMAP Brain Pre-frontal Cortex ENTPD6 0.32 0.10 bslmm 432 0.12 1.8e-15 6.1 6.4 1.3e-10 0.21 0.98 0.02 TRUE
55 YFS Blood ABHD12 0.15 0.35 bslmm 390 0.34 2.2e-118 7.2 7.4 1.3e-13 0.98 0.06 0.94 TRUE
56 YFS Blood NINL 0.04 0.03 lasso 8 0.03 2.8e-10 6.1 6.0 2.2e-09 0.46 0.99 0.01 FALSE
57 YFS Blood PYGB 0.36 0.49 enet 50 0.56 7.4e-226 5.8 5.6 2.8e-08 0.93 0.27 0.73 FALSE
58 The Cancer Genome Atlas Bladder Urothelial Carcinoma ABHD12 0.04 0.00 blup 77 0.02 6.6e-03 7.1 6.4 1.3e-10 0.93 0.04 0.53 FALSE
59 The Cancer Genome Atlas Breast Invasive Carcinoma PYGB 0.08 0.02 enet 7 0.03 1.7e-07 5.5 -5.7 1.5e-08 -0.54 0.90 0.08 FALSE
60 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma PYGB 0.08 0.04 blup 74 0.06 1.0e-03 7.1 -7.1 1.5e-12 -0.93 0.04 0.86 FALSE
61 The Cancer Genome Atlas Colon Adenocarcinoma NINL 0.20 0.06 lasso 4 0.08 2.7e-05 5.3 6.3 3.3e-10 0.59 0.36 0.31 FALSE
62 The Cancer Genome Atlas Colon Adenocarcinoma PYGB 0.09 0.07 lasso 3 0.06 3.4e-04 5.0 -5.2 2.0e-07 -0.61 0.06 0.67 TRUE
63 The Cancer Genome Atlas Esophageal Carcinoma LOC100134868 0.14 0.11 lasso 2 0.10 4.6e-04 -5.8 -5.7 1.3e-08 -0.62 0.00 0.92 TRUE
64 The Cancer Genome Atlas Glioblastoma Multiforme ABHD12 0.14 0.10 lasso 5 0.13 1.1e-04 6.6 6.9 5.6e-12 0.92 0.06 0.89 FALSE
65 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ABHD12 0.04 0.03 blup 77 0.04 4.0e-05 7.2 6.9 6.4e-12 0.96 0.05 0.95 FALSE
66 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GINS1 0.03 0.01 enet 13 0.02 4.3e-03 2.9 5.7 1.4e-08 0.84 0.03 0.66 FALSE
67 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ABHD12 0.03 0.01 blup 77 0.01 8.7e-03 5.0 7.1 1.5e-12 0.89 0.06 0.75 FALSE
68 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ENTPD6 0.29 0.17 lasso 4 0.18 1.0e-10 5.0 -6.0 1.9e-09 -0.83 0.02 0.98 FALSE
69 The Cancer Genome Atlas Brain Lower Grade Glioma ABHD12 0.04 0.06 blup 77 0.06 2.2e-07 7.1 7.3 3.2e-13 0.98 0.06 0.94 FALSE
70 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ABHD12 0.07 0.05 blup 77 0.05 2.4e-03 7.1 6.9 5.2e-12 0.97 0.05 0.85 FALSE
71 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ABHD12 0.08 0.09 blup 80 0.09 1.7e-06 7.2 6.9 4.1e-12 0.97 0.05 0.95 FALSE
72 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ENTPD6 0.07 0.07 lasso 1 0.04 9.2e-03 6.5 -6.5 9.7e-11 -0.95 0.01 0.90 FALSE
73 The Cancer Genome Atlas Prostate Adenocarcinoma ABHD12 0.03 0.02 lasso 4 0.03 5.8e-04 -6.6 6.8 9.5e-12 0.83 0.07 0.75 FALSE
74 The Cancer Genome Atlas Prostate Adenocarcinoma PYGB 0.21 0.13 enet 5 0.17 2.0e-17 5.0 -6.0 1.6e-09 -0.61 1.00 0.00 FALSE
75 The Cancer Genome Atlas Testicular Germ Cell Tumors NINL 0.11 0.03 blup 81 0.07 2.1e-03 -6.7 -6.8 1.3e-11 -0.95 0.03 0.73 FALSE
76 The Cancer Genome Atlas Thyroid Carcinoma ENTPD6 0.16 0.14 lasso 4 0.13 1.2e-12 6.5 -6.3 2.4e-10 -0.95 0.01 0.99 FALSE
77 The Cancer Genome Atlas Thyroid Carcinoma NINL 0.08 0.14 lasso 11 0.13 2.9e-12 7.1 -6.9 4.7e-12 -0.98 0.02 0.98 FALSE
78 The Cancer Genome Atlas Thyroid Carcinoma PYGB 0.10 0.08 lasso 7 0.07 1.4e-07 5.7 -6.3 3.3e-10 -0.62 0.89 0.11 FALSE