Best TWAS P=2.92e-08 · Best GWAS P=1.04e-07 conditioned to 0.0103
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | GRK4 | 0.38 | 0.25 | lasso | 5 | 0.29 | 5.1e-11 | -4.2 | 5.3 | 1.1e-07 | -0.59 | 0.32 | 0.63 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | NOP14 | 0.12 | 0.06 | enet | 11 | 0.09 | 2.9e-07 | -3.6 | 5.4 | 8.1e-08 | -0.50 | 0.16 | 0.80 | FALSE |
| 3 | GTEx | Colon Transverse | GRK4 | 0.27 | 0.25 | enet | 18 | 0.25 | 2.4e-12 | -4.5 | 5.2 | 1.8e-07 | -0.61 | 0.05 | 0.94 | FALSE |
| 4 | GTEx | Uterus | GRK4 | 0.31 | 0.24 | enet | 29 | 0.32 | 2.5e-07 | -4.7 | 5.1 | 2.6e-07 | -0.70 | 0.05 | 0.84 | FALSE |
| 5 | GTEx | Whole Blood | HTT | 0.10 | 0.00 | enet | 15 | 0.03 | 1.4e-03 | 3.5 | 5.5 | 2.9e-08 | -0.58 | 0.06 | 0.62 | TRUE |