Best TWAS P=2.24e-15 · Best GWAS P=2.23e-17 conditioned to 0.00254
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 0.0008 | 8.0 | -7.9 | 2.2e-15 | -0.94 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 0.0614 | 6.1 | 7.0 | 3.1e-12 | 0.90 | 0.10 | 0.80 | FALSE |
| 3 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 0.1030 | 6.1 | -7.2 | 7.0e-13 | -0.92 | 0.02 | 0.66 | FALSE |