[Hub]/) : Traits : Trunk fat mass :

chr12:107,433,672-111,634,281

Best TWAS P=2.83e-15 · Best GWAS P=1.36e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PRDM4 0.07 0.08 lasso 2 0.07 5.0e-09 7.8 7.8 7.7e-15 0.97 0.01 0.99 FALSE
2 GTEx Breast Mammary Tissue (Female) ALKBH2 0.22 0.09 lasso 3 0.12 2.8e-04 5.2 5.3 1.1e-07 -0.04 0.02 0.75 FALSE
3 GTEx Cells EBV-transformed lymphocytes KCTD10 0.36 0.18 lasso 7 0.19 1.0e-06 5.2 -5.3 1.1e-07 0.06 0.00 0.99 FALSE
4 GTEx Cells EBV-transformed lymphocytes ARPC3 0.13 0.09 lasso 4 0.04 2.0e-02 5.5 -5.6 1.8e-08 0.05 0.02 0.88 FALSE
5 GTEx Muscle Skeletal ARPC3 0.14 0.11 enet 23 0.10 2.2e-10 5.5 -5.2 1.9e-07 0.04 0.02 0.98 FALSE
6 GTEx Muscle Skeletal IFT81 0.08 0.08 lasso 5 0.07 1.7e-07 5.6 5.9 4.5e-09 -0.05 0.01 0.99 TRUE
7 GTEx Skin Sun Exposed Lower leg ARPC3 0.13 0.15 lasso 3 0.15 1.9e-12 5.5 -5.4 5.0e-08 0.04 0.03 0.97 FALSE
8 GTEx Spleen VPS29 0.24 0.01 enet 14 0.04 2.9e-02 3.7 5.2 2.2e-07 -0.03 0.02 0.73 FALSE
9 GTEx Testis ARPC3 0.16 0.16 lasso 3 0.14 7.5e-07 5.4 -5.4 5.4e-08 0.04 0.02 0.98 FALSE
10 GTEx Whole Blood PRDM4 0.10 0.08 lasso 5 0.05 1.8e-05 7.8 -7.9 2.8e-15 -0.99 0.01 0.99 TRUE
11 NTR Blood UBE3B 0.09 0.05 lasso 8 0.08 1.0e-25 4.6 5.7 1.2e-08 -0.05 0.01 0.98 TRUE
12 The Cancer Genome Atlas Breast Invasive Carcinoma PRDM4 0.01 0.01 lasso 1 0.01 6.3e-03 6.7 -6.7 2.0e-11 -0.87 0.02 0.84 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma RAD9B 0.04 0.03 lasso 5 0.01 7.0e-03 5.5 5.3 8.8e-08 -0.04 0.01 0.99 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma ASCL4 0.03 0.03 blup 49 0.03 2.9e-04 7.8 7.6 3.4e-14 0.88 0.01 0.94 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma PWP1 0.06 0.02 enet 13 0.03 1.4e-04 -1.7 5.2 1.9e-07 0.56 0.03 0.53 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma RAD9B 0.10 0.06 enet 5 0.06 1.2e-06 5.5 5.5 5.0e-08 -0.05 0.01 0.99 FALSE