Best TWAS P=9.91e-09 · Best GWAS P=1.44e-07 conditioned to 0.0117
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | RP11-552F3.10 | 0.12 | 0.02 | lasso | 2 | 0.03 | 4.4e-03 | 5.2 | -5.5 | 3.4e-08 | -0.70 | 0.02 | 0.49 | FALSE |
| 2 | GTEx | Nerve Tibial | TRIM65 | 0.25 | 0.10 | lasso | 6 | 0.16 | 8.7e-12 | 4.4 | 5.1 | 2.7e-07 | 0.79 | 0.01 | 0.98 | FALSE |
| 3 | YFS | Blood | GALK1 | 0.05 | 0.04 | enet | 26 | 0.04 | 2.4e-13 | 4.9 | -5.7 | 9.9e-09 | -0.55 | 0.03 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | TRIM65 | 0.08 | 0.02 | enet | 7 | 0.04 | 1.9e-02 | 4.4 | 5.2 | 2.0e-07 | 0.90 | 0.01 | 0.70 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | TRIM47 | 0.04 | 0.01 | blup | 30 | 0.03 | 2.7e-04 | 5.1 | -5.1 | 2.8e-07 | -0.71 | 0.01 | 0.72 | FALSE |