[Hub]/) : Traits : Trunk fat mass : ← →

chr17:65,123,352-66,885,526

Best TWAS P=5.71e-26 · Best GWAS P=1.52e-26 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LINC00674	0.12	0.13	enet	6	0.14	9.9e-12	9.1	9.1	1.3e-19	0.79	0.96	0.04	FALSE
2	GTEx	Adipose Subcutaneous	LRRC37A16P	0.10	0.10	enet	10	0.14	2.9e-11	9.1	6.3	3.6e-10	0.60	0.95	0.04	FALSE
3	GTEx	Adipose Subcutaneous	SH3GL1P3	0.08	0.06	lasso	5	0.04	2.5e-04	9.1	8.8	1.7e-18	0.80	0.06	0.90	FALSE
4	GTEx	Adipose Subcutaneous	RP11-147L13.8	0.28	0.09	enet	27	0.23	9.7e-19	5.4	5.7	9.2e-09	0.46	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	LINC00674	0.29	0.03	enet	40	0.03	6.9e-03	9.3	6.7	2.0e-11	0.63	0.08	0.49	FALSE
6	GTEx	Artery Aorta	LINC00674	0.12	0.00	lasso	5	0.01	1.5e-01	5.4	6.8	1.4e-11	0.58	0.08	0.32	FALSE
7	GTEx	Brain Cerebellum	BPTF	0.22	-0.01	lasso	10	-0.01	6.9e-01	8.7	-9.3	8.8e-21	-0.85	0.04	0.48	FALSE
8	GTEx	Brain Cortex	C17orf58	0.34	0.09	lasso	6	0.13	2.4e-04	10.5	10.1	6.3e-24	0.95	0.03	0.96	FALSE
9	GTEx	Cells Transformed fibroblasts	LINC00674	0.30	0.31	enet	10	0.32	1.5e-24	9.1	9.7	2.2e-22	0.86	1.00	0.00	FALSE
10	GTEx	Cells Transformed fibroblasts	LRRC37A16P	0.50	0.46	lasso	8	0.47	1.1e-38	9.1	9.3	1.4e-20	0.84	1.00	0.00	FALSE
11	GTEx	Cells Transformed fibroblasts	SH3GL1P3	0.26	0.31	lasso	7	0.31	1.5e-23	9.1	9.9	4.5e-23	0.90	1.00	0.00	FALSE
12	GTEx	Colon Sigmoid	LINC00674	0.42	0.09	lasso	8	0.12	5.5e-05	9.3	8.7	3.0e-18	0.80	0.15	0.65	FALSE
13	GTEx	Colon Sigmoid	RP11-147L13.8	0.12	0.20	lasso	3	0.15	4.4e-06	5.4	5.8	5.9e-09	0.51	0.36	0.44	FALSE
14	GTEx	Esophagus Mucosa	LRRC37A16P	0.11	0.06	enet	13	0.08	7.5e-06	6.9	-6.7	2.2e-11	-0.67	0.13	0.81	FALSE
15	GTEx	Esophagus Muscularis	LINC00674	0.11	0.04	lasso	6	0.07	7.9e-05	5.4	8.5	1.9e-17	0.77	0.18	0.79	FALSE
16	GTEx	Esophagus Muscularis	LRRC37A16P	0.12	0.03	enet	21	0.02	3.2e-02	10.4	7.4	1.1e-13	0.64	0.02	0.80	FALSE
17	GTEx	Heart Atrial Appendage	LINC00674	0.14	0.08	lasso	17	0.09	1.1e-04	5.4	8.1	5.3e-16	0.73	0.05	0.87	FALSE
18	GTEx	Lung	LINC00674	0.14	0.03	enet	22	0.08	2.1e-06	10.3	8.1	4.9e-16	0.80	0.18	0.82	FALSE
19	GTEx	Muscle Skeletal	LRRC37A16P	0.14	0.04	lasso	5	0.08	3.3e-08	5.4	-6.5	7.2e-11	-0.59	0.99	0.00	FALSE
20	GTEx	Nerve Tibial	LINC00674	0.09	0.01	enet	13	0.03	2.2e-03	5.4	7.2	5.6e-13	0.65	0.20	0.22	FALSE
21	GTEx	Nerve Tibial	LRRC37A16P	0.09	0.08	lasso	4	0.06	2.7e-05	9.1	9.3	1.9e-20	0.84	0.10	0.78	FALSE
22	GTEx	Skin Sun Exposed Lower leg	BPTF	0.10	0.01	enet	14	0.03	2.7e-03	8.9	-8.3	1.0e-16	-0.69	0.05	0.80	FALSE
23	GTEx	Spleen	C17orf58	0.30	-0.01	lasso	8	-0.01	4.6e-01	5.4	8.2	3.1e-16	0.81	0.03	0.34	FALSE
24	GTEx	Stomach	RP11-147L13.8	0.23	-0.01	enet	9	0.01	8.1e-02	3.1	6.9	3.9e-12	0.57	0.04	0.19	FALSE
25	GTEx	Thyroid	LINC00674	0.09	0.10	enet	16	0.12	4.0e-09	5.4	6.3	3.4e-10	0.61	0.56	0.39	FALSE
26	GTEx	Thyroid	SH3GL1P3	0.08	0.00	lasso	3	0.00	2.8e-01	5.4	6.3	4.0e-10	0.56	0.05	0.45	FALSE
27	GTEx	Thyroid	RP11-147L13.8	0.23	0.17	lasso	3	0.16	3.5e-12	5.4	5.6	1.8e-08	0.49	1.00	0.00	FALSE
28	YFS	Blood	KPNA2	0.01	0.01	blup	312	0.01	2.8e-04	9.3	-9.7	4.0e-22	-0.86	0.05	0.92	FALSE
29	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LOC651250	0.02	0.02	blup	2	0.03	1.9e-03	5.2	-5.7	1.1e-08	-0.51	0.00	0.44	FALSE
30	The Cancer Genome Atlas	Breast Invasive Carcinoma	LOC651250	0.01	0.01	lasso	1	0.01	1.5e-03	5.2	-5.2	2.3e-07	-0.54	0.00	0.64	FALSE
31	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LOC651250	0.07	0.05	lasso	1	0.05	1.8e-03	5.2	-5.2	2.3e-07	-0.54	0.00	0.60	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC651250	0.03	0.02	enet	2	0.02	2.0e-03	5.2	-5.7	8.9e-09	-0.55	0.00	0.59	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf58	0.02	0.02	lasso	2	0.01	1.8e-02	10.5	10.5	5.7e-26	1.00	0.00	0.76	TRUE