[Hub]/) : Traits : Trunk fat mass :

chr17:65,123,352-66,885,526

Best TWAS P=5.71e-26 · Best GWAS P=1.52e-26 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous LINC00674 0.12 0.13 enet 6 0.14 9.9e-12 9.1 9.1 1.3e-19 0.79 0.96 0.04 FALSE
2 GTEx Adipose Subcutaneous LRRC37A16P 0.10 0.10 enet 10 0.14 2.9e-11 9.1 6.3 3.6e-10 0.60 0.95 0.04 FALSE
3 GTEx Adipose Subcutaneous SH3GL1P3 0.08 0.06 lasso 5 0.04 2.5e-04 9.1 8.8 1.7e-18 0.80 0.06 0.90 FALSE
4 GTEx Adipose Subcutaneous RP11-147L13.8 0.28 0.09 enet 27 0.23 9.7e-19 5.4 5.7 9.2e-09 0.46 1.00 0.00 FALSE
5 GTEx Adipose Visceral Omentum LINC00674 0.29 0.03 enet 40 0.03 6.9e-03 9.3 6.7 2.0e-11 0.63 0.08 0.49 FALSE
6 GTEx Artery Aorta LINC00674 0.12 0.00 lasso 5 0.01 1.5e-01 5.4 6.8 1.4e-11 0.58 0.08 0.32 FALSE
7 GTEx Brain Cerebellum BPTF 0.22 -0.01 lasso 10 -0.01 6.9e-01 8.7 -9.3 8.8e-21 -0.85 0.04 0.48 FALSE
8 GTEx Brain Cortex C17orf58 0.34 0.09 lasso 6 0.13 2.4e-04 10.5 10.1 6.3e-24 0.95 0.03 0.96 FALSE
9 GTEx Cells Transformed fibroblasts LINC00674 0.30 0.31 enet 10 0.32 1.5e-24 9.1 9.7 2.2e-22 0.86 1.00 0.00 FALSE
10 GTEx Cells Transformed fibroblasts LRRC37A16P 0.50 0.46 lasso 8 0.47 1.1e-38 9.1 9.3 1.4e-20 0.84 1.00 0.00 FALSE
11 GTEx Cells Transformed fibroblasts SH3GL1P3 0.26 0.31 lasso 7 0.31 1.5e-23 9.1 9.9 4.5e-23 0.90 1.00 0.00 FALSE
12 GTEx Colon Sigmoid LINC00674 0.42 0.09 lasso 8 0.12 5.5e-05 9.3 8.7 3.0e-18 0.80 0.15 0.65 FALSE
13 GTEx Colon Sigmoid RP11-147L13.8 0.12 0.20 lasso 3 0.15 4.4e-06 5.4 5.8 5.9e-09 0.51 0.36 0.44 FALSE
14 GTEx Esophagus Mucosa LRRC37A16P 0.11 0.06 enet 13 0.08 7.5e-06 6.9 -6.7 2.2e-11 -0.67 0.13 0.81 FALSE
15 GTEx Esophagus Muscularis LINC00674 0.11 0.04 lasso 6 0.07 7.9e-05 5.4 8.5 1.9e-17 0.77 0.18 0.79 FALSE
16 GTEx Esophagus Muscularis LRRC37A16P 0.12 0.03 enet 21 0.02 3.2e-02 10.4 7.4 1.1e-13 0.64 0.02 0.80 FALSE
17 GTEx Heart Atrial Appendage LINC00674 0.14 0.08 lasso 17 0.09 1.1e-04 5.4 8.1 5.3e-16 0.73 0.05 0.87 FALSE
18 GTEx Lung LINC00674 0.14 0.03 enet 22 0.08 2.1e-06 10.3 8.1 4.9e-16 0.80 0.18 0.82 FALSE
19 GTEx Muscle Skeletal LRRC37A16P 0.14 0.04 lasso 5 0.08 3.3e-08 5.4 -6.5 7.2e-11 -0.59 0.99 0.00 FALSE
20 GTEx Nerve Tibial LINC00674 0.09 0.01 enet 13 0.03 2.2e-03 5.4 7.2 5.6e-13 0.65 0.20 0.22 FALSE
21 GTEx Nerve Tibial LRRC37A16P 0.09 0.08 lasso 4 0.06 2.7e-05 9.1 9.3 1.9e-20 0.84 0.10 0.78 FALSE
22 GTEx Skin Sun Exposed Lower leg BPTF 0.10 0.01 enet 14 0.03 2.7e-03 8.9 -8.3 1.0e-16 -0.69 0.05 0.80 FALSE
23 GTEx Spleen C17orf58 0.30 -0.01 lasso 8 -0.01 4.6e-01 5.4 8.2 3.1e-16 0.81 0.03 0.34 FALSE
24 GTEx Stomach RP11-147L13.8 0.23 -0.01 enet 9 0.01 8.1e-02 3.1 6.9 3.9e-12 0.57 0.04 0.19 FALSE
25 GTEx Thyroid LINC00674 0.09 0.10 enet 16 0.12 4.0e-09 5.4 6.3 3.4e-10 0.61 0.56 0.39 FALSE
26 GTEx Thyroid SH3GL1P3 0.08 0.00 lasso 3 0.00 2.8e-01 5.4 6.3 4.0e-10 0.56 0.05 0.45 FALSE
27 GTEx Thyroid RP11-147L13.8 0.23 0.17 lasso 3 0.16 3.5e-12 5.4 5.6 1.8e-08 0.49 1.00 0.00 FALSE
28 YFS Blood KPNA2 0.01 0.01 blup 312 0.01 2.8e-04 9.3 -9.7 4.0e-22 -0.86 0.05 0.92 FALSE
29 The Cancer Genome Atlas Bladder Urothelial Carcinoma LOC651250 0.02 0.02 blup 2 0.03 1.9e-03 5.2 -5.7 1.1e-08 -0.51 0.00 0.44 FALSE
30 The Cancer Genome Atlas Breast Invasive Carcinoma LOC651250 0.01 0.01 lasso 1 0.01 1.5e-03 5.2 -5.2 2.3e-07 -0.54 0.00 0.64 FALSE
31 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LOC651250 0.07 0.05 lasso 1 0.05 1.8e-03 5.2 -5.2 2.3e-07 -0.54 0.00 0.60 FALSE
32 The Cancer Genome Atlas Prostate Adenocarcinoma LOC651250 0.03 0.02 enet 2 0.02 2.0e-03 5.2 -5.7 8.9e-09 -0.55 0.00 0.59 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma C17orf58 0.02 0.02 lasso 2 0.01 1.8e-02 10.5 10.5 5.7e-26 1.00 0.00 0.76 TRUE