[Hub]/) : Traits : Trunk fat mass :

chr5:12,225-1,462,720

Best TWAS P=2.03e-09 · Best GWAS P=4.77e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SDHA 0.12 0.06 bslmm 290 0.11 8.6e-14 5.6 -5.2 1.5e-07 -0.86 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous SDHA 0.10 0.09 lasso 5 0.07 1.9e-06 5.8 5.5 4.2e-08 0.97 0.01 0.99 FALSE
3 GTEx Artery Aorta PDCD6 0.26 0.17 lasso 4 0.14 2.8e-08 5.8 -5.7 1.6e-08 -0.99 0.01 0.99 FALSE
4 GTEx Artery Tibial PDCD6 0.22 0.07 lasso 4 0.06 2.1e-05 5.8 -5.1 2.8e-07 -0.94 0.01 0.99 FALSE
5 GTEx Brain Frontal Cortex BA9 AHRR 0.32 0.21 lasso 4 0.18 1.6e-05 5.8 5.7 1.6e-08 0.93 0.01 0.92 FALSE
6 GTEx Cells Transformed fibroblasts SDHA 0.23 0.18 lasso 2 0.17 1.6e-12 5.8 5.8 6.9e-09 0.99 0.01 0.99 FALSE
7 GTEx Cells Transformed fibroblasts CTD-2083E4.5 0.09 0.07 lasso 3 0.05 1.2e-04 5.8 -5.8 6.7e-09 -0.99 0.01 0.98 FALSE
8 GTEx Esophagus Gastroesophageal Junction CTD-2083E4.5 0.25 0.11 enet 10 0.12 3.3e-05 3.4 -5.7 1.4e-08 -0.47 0.09 0.73 FALSE
9 GTEx Muscle Skeletal ZDHHC11B 0.11 0.01 enet 16 0.03 4.0e-04 3.7 5.4 8.1e-08 0.57 0.07 0.82 FALSE
10 GTEx Nerve Tibial CCDC127 0.05 0.01 lasso 4 0.02 2.2e-02 4.6 5.5 2.8e-08 0.86 0.04 0.80 FALSE
11 GTEx Pancreas AC026740.1 0.19 0.01 enet 14 0.08 3.6e-04 2.4 5.5 4.7e-08 0.34 0.27 0.37 TRUE
12 GTEx Thyroid CTD-2083E4.5 0.07 0.06 lasso 2 0.04 3.6e-04 5.9 -6.0 2.7e-09 -0.99 0.01 0.98 FALSE
13 GTEx Whole Blood SDHA 0.05 0.01 lasso 5 0.01 3.4e-02 4.9 -5.5 5.1e-08 -0.90 0.03 0.92 FALSE
14 NTR Blood CCDC127 0.02 0.01 blup 284 0.02 1.5e-06 1.0 -5.3 1.4e-07 -0.62 0.16 0.82 FALSE
15 YFS Blood PDCD6 0.03 0.03 bslmm 276 0.03 1.6e-09 5.8 5.9 3.7e-09 0.90 0.01 0.99 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PDCD6 0.03 0.02 blup 49 0.02 2.9e-03 5.6 6.0 2.0e-09 0.95 0.02 0.96 TRUE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SDHA 0.04 0.03 blup 62 0.05 3.3e-06 5.8 5.6 1.8e-08 0.87 0.02 0.98 FALSE
18 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma LRRC14B 0.08 0.04 lasso 5 0.03 6.7e-03 5.6 5.6 2.1e-08 0.97 0.01 0.96 FALSE
19 The Cancer Genome Atlas Liver Hepatocellular Carcinoma AHRR 0.11 0.05 lasso 3 0.07 2.5e-04 5.8 5.8 6.5e-09 0.86 0.01 0.93 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma PDCD6 0.07 0.06 enet 5 0.07 2.0e-07 5.9 -5.6 1.8e-08 -0.91 0.01 0.99 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma SDHA 0.06 0.09 lasso 13 0.08 1.8e-08 5.8 5.7 1.1e-08 0.99 0.01 0.99 FALSE