[Hub]/) : Traits : Trunk fat-free mass : ← →

chr10:68,997,881-71,474,493

Best TWAS P=9.01e-19 · Best GWAS P=1.15e-17 conditioned to 0.00913

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
72	The Cancer Genome Atlas	Soft Tissue Sarcoma	SLC25A16	0.07	0.03	blup	42	0.02	1.7e-02	-8.1	-8.8	9.0e-19	-0.53	0.08	0.45	TRUE
27	GTEx	Esophagus Mucosa	DNA2	0.32	0.12	lasso	4	0.17	2.1e-11	-6.3	5.5	3.9e-08	0.29	0.99	0.01	TRUE
30	GTEx	Heart Atrial Appendage	PBLD	0.08	0.02	lasso	2	0.02	6.1e-02	-8.0	-8.5	2.3e-17	-0.40	0.10	0.17	FALSE
55	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DNA2	0.08	0.09	lasso	1	0.06	7.3e-04	-8.1	8.1	7.1e-16	0.38	0.00	0.99	FALSE
69	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SLC25A16	0.02	0.02	enet	8	0.02	7.7e-04	-8.1	-7.7	2.0e-14	-0.37	0.06	0.34	FALSE
65	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC25A16	0.05	0.01	blup	42	0.02	2.9e-03	-6.3	-7.4	1.6e-13	-0.50	0.11	0.72	FALSE
51	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PBLD	0.06	0.07	lasso	2	0.04	2.3e-04	-6.9	-6.9	4.0e-12	-0.31	0.01	0.98	FALSE
73	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DNA2	0.14	0.07	blup	43	0.08	8.6e-04	-6.4	-6.8	8.7e-12	-0.38	0.08	0.45	FALSE
8	GTEx	Artery Coronary	DNA2	0.12	0.12	lasso	5	0.12	5.3e-05	-6.3	6.8	1.4e-11	0.34	0.29	0.26	FALSE
50	YFS	Blood	SLC25A16	0.09	0.13	lasso	3	0.13	6.8e-39	-6.3	-6.7	1.6e-11	-0.34	0.80	0.20	FALSE
62	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DNA2	0.05	0.00	blup	43	0.00	3.0e-01	-6.3	6.7	1.7e-11	0.38	0.01	0.85	FALSE
49	ROSMAP	Brain Pre-frontal Cortex	SLC25A16	0.17	0.11	lasso	6	0.15	2.9e-19	-4.9	-6.7	2.7e-11	-0.33	0.86	0.14	FALSE
38	GTEx	Pancreas	DNA2	0.12	0.06	enet	9	0.08	4.1e-04	-4.9	6.6	3.2e-11	0.40	0.32	0.38	FALSE
60	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PBLD	0.10	0.03	lasso	3	0.04	2.2e-05	-6.9	-6.6	4.8e-11	-0.31	0.01	0.99	FALSE
47	NTR	Blood	SLC25A16	0.03	0.02	enet	16	0.03	1.7e-09	-6.3	-6.6	5.4e-11	-0.40	0.55	0.45	FALSE
61	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ATOH7	0.08	0.04	enet	19	0.06	3.1e-04	-4.3	6.5	6.4e-11	0.23	0.03	0.86	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	SLC25A16	0.05	0.05	lasso	3	0.04	3.8e-05	-6.3	-6.5	7.3e-11	-0.35	0.25	0.23	FALSE
24	GTEx	Cells Transformed fibroblasts	SLC25A16	0.10	0.02	enet	25	0.01	2.5e-02	-4.4	-6.5	9.9e-11	-0.53	0.70	0.20	FALSE
17	GTEx	Brain Hypothalamus	SLC25A16	0.20	0.19	lasso	5	0.14	3.6e-04	-6.3	-6.3	2.9e-10	-0.31	0.15	0.06	FALSE
23	GTEx	Cells EBV-transformed lymphocytes	DNA2	0.32	0.14	lasso	2	0.10	2.9e-04	-6.3	6.3	2.9e-10	0.32	0.42	0.11	FALSE
54	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC25A16	0.01	0.02	lasso	2	0.01	5.5e-04	-6.3	-6.3	3.1e-10	-0.32	0.34	0.07	FALSE
70	The Cancer Genome Atlas	Prostate Adenocarcinoma	PBLD	0.03	0.01	blup	76	0.01	1.3e-02	-6.2	-6.3	3.3e-10	-0.29	0.06	0.36	FALSE
33	GTEx	Lung	DNA2	0.22	0.17	enet	12	0.24	3.9e-18	-6.3	6.3	3.5e-10	0.34	1.00	0.00	FALSE
57	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PBLD	0.03	0.03	lasso	9	0.02	1.6e-03	-6.1	-6.2	4.6e-10	-0.25	0.04	0.70	FALSE
56	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ATOH7	0.05	0.01	lasso	3	0.02	2.6e-03	-6.9	6.2	5.3e-10	0.26	0.01	0.81	FALSE
64	The Cancer Genome Atlas	Brain Lower Grade Glioma	PBLD	0.12	0.18	enet	10	0.18	6.7e-20	-5.3	-6.2	6.0e-10	-0.34	0.34	0.66	FALSE
39	GTEx	Skin Not Sun Exposed Suprapubic	DNA2	0.29	0.16	lasso	14	0.22	2.4e-12	-5.0	6.2	6.7e-10	0.31	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	DNA2	0.32	0.18	lasso	9	0.20	1.9e-10	-6.3	6.1	8.0e-10	0.33	1.00	0.00	FALSE
26	GTEx	Colon Transverse	DNA2	0.20	0.17	lasso	4	0.14	2.5e-07	-6.3	6.0	1.4e-09	0.32	0.71	0.28	FALSE
36	GTEx	Ovary	DNA2	0.15	0.12	lasso	3	0.06	1.7e-02	-5.9	6.0	2.4e-09	0.33	0.12	0.06	FALSE
58	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ATOH7	0.16	0.06	enet	15	0.09	3.7e-10	-4.3	5.9	3.2e-09	0.27	0.04	0.96	FALSE
11	GTEx	Brain Caudate basal ganglia	PBLD	0.17	0.14	lasso	16	0.13	1.2e-04	-5.3	-5.9	3.3e-09	-0.27	0.64	0.02	FALSE
45	METSIM	Adipose	PBLD	0.16	0.15	lasso	12	0.14	6.4e-21	-5.3	-5.9	3.5e-09	-0.29	1.00	0.00	FALSE
7	GTEx	Artery Aorta	DNA2	0.22	0.17	lasso	6	0.16	5.1e-09	-5.0	5.9	4.2e-09	0.30	0.99	0.01	FALSE
29	GTEx	Esophagus Muscularis	DNA2	0.35	0.24	enet	10	0.33	9.3e-21	-6.3	5.8	5.2e-09	0.31	1.00	0.00	FALSE
48	ROSMAP	Brain Pre-frontal Cortex	PBLD	0.04	0.01	bslmm	388	0.02	1.3e-03	-4.3	-5.8	5.5e-09	-0.32	0.95	0.01	FALSE
10	GTEx	Artery Tibial	DNA2	0.10	0.09	lasso	3	0.11	4.4e-09	-6.3	5.8	6.3e-09	0.30	0.99	0.00	FALSE
22	GTEx	Breast Mammary Tissue (Female)	DNA2	0.15	0.10	lasso	3	0.07	3.6e-03	-4.9	5.8	6.3e-09	0.30	0.16	0.22	FALSE
42	GTEx	Stomach	DNA2	0.31	0.13	lasso	11	0.19	2.3e-09	-5.0	5.8	7.4e-09	0.31	0.88	0.12	FALSE
5	GTEx	Adrenal Gland	DNA2	0.16	0.12	lasso	6	0.10	2.2e-04	-5.0	5.8	8.1e-09	0.30	0.47	0.10	FALSE
14	GTEx	Brain Cerebellum	SLC25A16	0.22	0.15	lasso	9	0.19	2.2e-06	-5.1	-5.8	8.6e-09	-0.32	0.31	0.08	FALSE
35	GTEx	Muscle Skeletal	DNA2	0.18	0.16	lasso	4	0.19	1.7e-18	-5.0	5.7	9.4e-09	0.29	1.00	0.00	FALSE
63	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PBLD	0.06	0.06	enet	6	0.06	2.5e-04	-5.7	-5.7	1.2e-08	-0.29	0.23	0.30	FALSE
41	GTEx	Spleen	DNA2	0.35	0.19	lasso	8	0.15	1.3e-04	-6.3	5.7	1.3e-08	0.29	0.19	0.08	FALSE
21	GTEx	Breast Mammary Tissue (Male)	DNA2	0.32	0.14	lasso	5	0.07	1.2e-02	-4.9	5.7	1.5e-08	0.30	0.33	0.07	FALSE
3	GTEx	Adipose Subcutaneous	DNA2	0.31	0.23	enet	10	0.25	2.3e-20	-5.0	5.6	2.1e-08	0.28	1.00	0.00	FALSE
13	GTEx	Brain Cerebellar Hemisphere	DNA2	0.28	0.29	lasso	11	0.27	1.4e-07	-5.1	5.6	2.1e-08	0.29	0.71	0.04	FALSE
19	GTEx	Breast Mammary Tissue	DNA2	0.30	0.26	lasso	7	0.26	8.2e-14	-4.9	5.5	2.9e-08	0.29	1.00	0.00	FALSE
31	GTEx	Heart Left Ventricle	DNA2	0.10	0.12	lasso	6	0.11	3.0e-06	-5.0	5.5	3.3e-08	0.28	0.86	0.08	FALSE
44	GTEx	Thyroid	DNA2	0.18	0.19	lasso	5	0.19	2.9e-14	-5.0	5.5	3.7e-08	0.28	1.00	0.00	FALSE
43	GTEx	Testis	SLC25A16	0.24	0.23	lasso	4	0.19	7.3e-09	-5.0	-5.5	4.2e-08	-0.28	0.99	0.01	FALSE
71	The Cancer Genome Atlas	Prostate Adenocarcinoma	SLC25A16	0.05	0.02	blup	42	0.05	5.5e-06	-3.5	-5.5	4.5e-08	-0.37	0.78	0.02	FALSE
15	GTEx	Brain Cerebellum	DNA2	0.45	0.47	lasso	3	0.47	1.0e-15	-5.0	5.5	5.1e-08	0.27	1.00	0.00	FALSE
74	The Cancer Genome Atlas	Thyroid Carcinoma	PBLD	0.06	0.09	lasso	2	0.09	1.1e-08	-5.3	-5.4	5.4e-08	-0.28	0.61	0.39	FALSE
28	GTEx	Esophagus Muscularis	PBLD	0.07	0.03	lasso	7	0.02	1.5e-02	-5.3	-5.4	5.5e-08	-0.28	0.70	0.02	FALSE
68	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PBLD	0.02	0.01	blup	76	0.01	1.5e-02	-5.8	-5.4	5.8e-08	-0.27	0.15	0.23	FALSE
66	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	DNA2	0.08	0.05	blup	43	0.09	7.5e-05	-4.2	5.4	6.6e-08	0.30	0.02	0.90	FALSE
52	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SLC25A16	0.03	0.02	blup	42	0.02	6.7e-03	-6.3	-5.4	7.2e-08	-0.27	0.13	0.05	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PBLD	0.07	0.09	lasso	3	0.08	4.8e-10	-5.3	-5.4	7.5e-08	-0.27	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	PBLD	0.14	0.12	lasso	3	0.09	3.8e-08	-5.3	-5.3	8.7e-08	-0.27	1.00	0.00	FALSE
25	GTEx	Cells Transformed fibroblasts	DNA2	0.16	0.09	lasso	8	0.14	7.6e-11	-4.2	5.3	9.2e-08	0.35	0.99	0.01	FALSE
16	GTEx	Brain Frontal Cortex BA9	PBLD	0.15	0.00	lasso	3	0.01	1.6e-01	-5.3	-5.3	1.0e-07	-0.26	0.33	0.04	FALSE
32	GTEx	Liver	DNA2	0.26	0.15	lasso	7	0.19	6.5e-06	-5.1	5.3	1.0e-07	0.32	0.30	0.08	FALSE
37	GTEx	Pancreas	PBLD	0.18	0.17	enet	6	0.16	3.1e-07	-5.3	-5.3	1.1e-07	-0.27	0.75	0.02	FALSE
6	GTEx	Artery Aorta	PBLD	0.14	0.10	lasso	8	0.06	3.1e-04	-5.3	-5.3	1.2e-07	-0.24	0.99	0.00	FALSE
40	GTEx	Skin Sun Exposed Lower leg	DNA2	0.23	0.15	lasso	6	0.14	1.3e-11	-5.1	5.3	1.2e-07	0.25	1.00	0.00	FALSE
34	GTEx	Muscle Skeletal	PBLD	0.11	0.10	lasso	12	0.12	5.1e-12	-4.0	-5.3	1.4e-07	-0.23	1.00	0.00	FALSE
9	GTEx	Artery Tibial	PBLD	0.06	0.09	lasso	2	0.07	2.5e-06	-5.3	-5.2	1.5e-07	-0.26	0.92	0.01	FALSE
18	GTEx	Brain Nucleus accumbens basal ganglia	PBLD	0.20	0.13	lasso	2	0.09	1.7e-03	-5.3	-5.2	1.5e-07	-0.26	0.23	0.04	FALSE
67	The Cancer Genome Atlas	Lung Adenocarcinoma	SLC25A16	0.03	0.03	lasso	2	0.02	1.4e-03	-6.3	-5.3	1.5e-07	-0.28	0.12	0.04	FALSE
20	GTEx	Breast Mammary Tissue	HERC4	0.07	0.00	lasso	3	0.02	3.6e-02	-5.8	-5.2	1.7e-07	-0.27	0.13	0.05	FALSE
53	The Cancer Genome Atlas	Breast Invasive Carcinoma	PBLD	0.03	0.01	enet	6	0.02	2.9e-05	-5.3	-5.2	1.8e-07	-0.26	0.71	0.29	FALSE
59	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DNA2	0.11	0.09	lasso	8	0.09	5.7e-10	-4.9	5.2	2.0e-07	0.28	0.94	0.06	FALSE
12	GTEx	Brain Cerebellar Hemisphere	SLC25A16	0.30	0.16	lasso	3	0.08	4.0e-03	-5.1	-5.2	2.3e-07	-0.26	0.57	0.05	FALSE
46	NTR	Blood	KIAA1279	0.02	0.01	enet	20	0.01	9.2e-05	-4.1	-5.1	2.7e-07	-0.33	0.43	0.06	FALSE