[Hub]/) : Traits : Trunk fat-free mass :

chr10:68,997,881-71,474,493

Best TWAS P=9.01e-19 · Best GWAS P=1.15e-17 conditioned to 0.00913

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PBLD 0.07 0.09 lasso 3 0.08 4.8e-10 -5.3 -5.4 7.5e-08 -0.27 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous PBLD 0.14 0.12 lasso 3 0.09 3.8e-08 -5.3 -5.3 8.7e-08 -0.27 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous DNA2 0.31 0.23 enet 10 0.25 2.3e-20 -5.0 5.6 2.1e-08 0.28 1.00 0.00 FALSE
4 GTEx Adipose Visceral Omentum DNA2 0.32 0.18 lasso 9 0.20 1.9e-10 -6.3 6.1 8.0e-10 0.33 1.00 0.00 FALSE
5 GTEx Adrenal Gland DNA2 0.16 0.12 lasso 6 0.10 2.2e-04 -5.0 5.8 8.1e-09 0.30 0.47 0.10 FALSE
6 GTEx Artery Aorta PBLD 0.14 0.10 lasso 8 0.06 3.1e-04 -5.3 -5.3 1.2e-07 -0.24 0.99 0.00 FALSE
7 GTEx Artery Aorta DNA2 0.22 0.17 lasso 6 0.16 5.1e-09 -5.0 5.9 4.2e-09 0.30 0.99 0.01 FALSE
8 GTEx Artery Coronary DNA2 0.12 0.12 lasso 5 0.12 5.3e-05 -6.3 6.8 1.4e-11 0.34 0.29 0.26 FALSE
9 GTEx Artery Tibial PBLD 0.06 0.09 lasso 2 0.07 2.5e-06 -5.3 -5.2 1.5e-07 -0.26 0.92 0.01 FALSE
10 GTEx Artery Tibial DNA2 0.10 0.09 lasso 3 0.11 4.4e-09 -6.3 5.8 6.3e-09 0.30 0.99 0.00 FALSE
11 GTEx Brain Caudate basal ganglia PBLD 0.17 0.14 lasso 16 0.13 1.2e-04 -5.3 -5.9 3.3e-09 -0.27 0.64 0.02 FALSE
12 GTEx Brain Cerebellar Hemisphere SLC25A16 0.30 0.16 lasso 3 0.08 4.0e-03 -5.1 -5.2 2.3e-07 -0.26 0.57 0.05 FALSE
13 GTEx Brain Cerebellar Hemisphere DNA2 0.28 0.29 lasso 11 0.27 1.4e-07 -5.1 5.6 2.1e-08 0.29 0.71 0.04 FALSE
14 GTEx Brain Cerebellum SLC25A16 0.22 0.15 lasso 9 0.19 2.2e-06 -5.1 -5.8 8.6e-09 -0.32 0.31 0.08 FALSE
15 GTEx Brain Cerebellum DNA2 0.45 0.47 lasso 3 0.47 1.0e-15 -5.0 5.5 5.1e-08 0.27 1.00 0.00 FALSE
16 GTEx Brain Frontal Cortex BA9 PBLD 0.15 0.00 lasso 3 0.01 1.6e-01 -5.3 -5.3 1.0e-07 -0.26 0.33 0.04 FALSE
17 GTEx Brain Hypothalamus SLC25A16 0.20 0.19 lasso 5 0.14 3.6e-04 -6.3 -6.3 2.9e-10 -0.31 0.15 0.06 FALSE
18 GTEx Brain Nucleus accumbens basal ganglia PBLD 0.20 0.13 lasso 2 0.09 1.7e-03 -5.3 -5.2 1.5e-07 -0.26 0.23 0.04 FALSE
19 GTEx Breast Mammary Tissue DNA2 0.30 0.26 lasso 7 0.26 8.2e-14 -4.9 5.5 2.9e-08 0.29 1.00 0.00 FALSE
20 GTEx Breast Mammary Tissue HERC4 0.07 0.00 lasso 3 0.02 3.6e-02 -5.8 -5.2 1.7e-07 -0.27 0.13 0.05 FALSE
21 GTEx Breast Mammary Tissue (Male) DNA2 0.32 0.14 lasso 5 0.07 1.2e-02 -4.9 5.7 1.5e-08 0.30 0.33 0.07 FALSE
22 GTEx Breast Mammary Tissue (Female) DNA2 0.15 0.10 lasso 3 0.07 3.6e-03 -4.9 5.8 6.3e-09 0.30 0.16 0.22 FALSE
23 GTEx Cells EBV-transformed lymphocytes DNA2 0.32 0.14 lasso 2 0.10 2.9e-04 -6.3 6.3 2.9e-10 0.32 0.42 0.11 FALSE
24 GTEx Cells Transformed fibroblasts SLC25A16 0.10 0.02 enet 25 0.01 2.5e-02 -4.4 -6.5 9.9e-11 -0.53 0.70 0.20 FALSE
25 GTEx Cells Transformed fibroblasts DNA2 0.16 0.09 lasso 8 0.14 7.6e-11 -4.2 5.3 9.2e-08 0.35 0.99 0.01 FALSE
26 GTEx Colon Transverse DNA2 0.20 0.17 lasso 4 0.14 2.5e-07 -6.3 6.0 1.4e-09 0.32 0.71 0.28 FALSE
27 GTEx Esophagus Mucosa DNA2 0.32 0.12 lasso 4 0.17 2.1e-11 -6.3 5.5 3.9e-08 0.29 0.99 0.01 TRUE
28 GTEx Esophagus Muscularis PBLD 0.07 0.03 lasso 7 0.02 1.5e-02 -5.3 -5.4 5.5e-08 -0.28 0.70 0.02 FALSE
29 GTEx Esophagus Muscularis DNA2 0.35 0.24 enet 10 0.33 9.3e-21 -6.3 5.8 5.2e-09 0.31 1.00 0.00 FALSE
30 GTEx Heart Atrial Appendage PBLD 0.08 0.02 lasso 2 0.02 6.1e-02 -8.0 -8.5 2.3e-17 -0.40 0.10 0.17 FALSE
31 GTEx Heart Left Ventricle DNA2 0.10 0.12 lasso 6 0.11 3.0e-06 -5.0 5.5 3.3e-08 0.28 0.86 0.08 FALSE
32 GTEx Liver DNA2 0.26 0.15 lasso 7 0.19 6.5e-06 -5.1 5.3 1.0e-07 0.32 0.30 0.08 FALSE
33 GTEx Lung DNA2 0.22 0.17 enet 12 0.24 3.9e-18 -6.3 6.3 3.5e-10 0.34 1.00 0.00 FALSE
34 GTEx Muscle Skeletal PBLD 0.11 0.10 lasso 12 0.12 5.1e-12 -4.0 -5.3 1.4e-07 -0.23 1.00 0.00 FALSE
35 GTEx Muscle Skeletal DNA2 0.18 0.16 lasso 4 0.19 1.7e-18 -5.0 5.7 9.4e-09 0.29 1.00 0.00 FALSE
36 GTEx Ovary DNA2 0.15 0.12 lasso 3 0.06 1.7e-02 -5.9 6.0 2.4e-09 0.33 0.12 0.06 FALSE
37 GTEx Pancreas PBLD 0.18 0.17 enet 6 0.16 3.1e-07 -5.3 -5.3 1.1e-07 -0.27 0.75 0.02 FALSE
38 GTEx Pancreas DNA2 0.12 0.06 enet 9 0.08 4.1e-04 -4.9 6.6 3.2e-11 0.40 0.32 0.38 FALSE
39 GTEx Skin Not Sun Exposed Suprapubic DNA2 0.29 0.16 lasso 14 0.22 2.4e-12 -5.0 6.2 6.7e-10 0.31 1.00 0.00 FALSE
40 GTEx Skin Sun Exposed Lower leg DNA2 0.23 0.15 lasso 6 0.14 1.3e-11 -5.1 5.3 1.2e-07 0.25 1.00 0.00 FALSE
41 GTEx Spleen DNA2 0.35 0.19 lasso 8 0.15 1.3e-04 -6.3 5.7 1.3e-08 0.29 0.19 0.08 FALSE
42 GTEx Stomach DNA2 0.31 0.13 lasso 11 0.19 2.3e-09 -5.0 5.8 7.4e-09 0.31 0.88 0.12 FALSE
43 GTEx Testis SLC25A16 0.24 0.23 lasso 4 0.19 7.3e-09 -5.0 -5.5 4.2e-08 -0.28 0.99 0.01 FALSE
44 GTEx Thyroid DNA2 0.18 0.19 lasso 5 0.19 2.9e-14 -5.0 5.5 3.7e-08 0.28 1.00 0.00 FALSE
45 METSIM Adipose PBLD 0.16 0.15 lasso 12 0.14 6.4e-21 -5.3 -5.9 3.5e-09 -0.29 1.00 0.00 FALSE
46 NTR Blood KIAA1279 0.02 0.01 enet 20 0.01 9.2e-05 -4.1 -5.1 2.7e-07 -0.33 0.43 0.06 FALSE
47 NTR Blood SLC25A16 0.03 0.02 enet 16 0.03 1.7e-09 -6.3 -6.6 5.4e-11 -0.40 0.55 0.45 FALSE
48 ROSMAP Brain Pre-frontal Cortex PBLD 0.04 0.01 bslmm 388 0.02 1.3e-03 -4.3 -5.8 5.5e-09 -0.32 0.95 0.01 FALSE
49 ROSMAP Brain Pre-frontal Cortex SLC25A16 0.17 0.11 lasso 6 0.15 2.9e-19 -4.9 -6.7 2.7e-11 -0.33 0.86 0.14 FALSE
50 YFS Blood SLC25A16 0.09 0.13 lasso 3 0.13 6.8e-39 -6.3 -6.7 1.6e-11 -0.34 0.80 0.20 FALSE
51 The Cancer Genome Atlas Bladder Urothelial Carcinoma PBLD 0.06 0.07 lasso 2 0.04 2.3e-04 -6.9 -6.9 4.0e-12 -0.31 0.01 0.98 FALSE
52 The Cancer Genome Atlas Bladder Urothelial Carcinoma SLC25A16 0.03 0.02 blup 42 0.02 6.7e-03 -6.3 -5.4 7.2e-08 -0.27 0.13 0.05 FALSE
53 The Cancer Genome Atlas Breast Invasive Carcinoma PBLD 0.03 0.01 enet 6 0.02 2.9e-05 -5.3 -5.2 1.8e-07 -0.26 0.71 0.29 FALSE
54 The Cancer Genome Atlas Breast Invasive Carcinoma SLC25A16 0.01 0.02 lasso 2 0.01 5.5e-04 -6.3 -6.3 3.1e-10 -0.32 0.34 0.07 FALSE
55 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DNA2 0.08 0.09 lasso 1 0.06 7.3e-04 -8.1 8.1 7.1e-16 0.38 0.00 0.99 FALSE
56 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATOH7 0.05 0.01 lasso 3 0.02 2.6e-03 -6.9 6.2 5.3e-10 0.26 0.01 0.81 FALSE
57 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PBLD 0.03 0.03 lasso 9 0.02 1.6e-03 -6.1 -6.2 4.6e-10 -0.25 0.04 0.70 FALSE
58 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ATOH7 0.16 0.06 enet 15 0.09 3.7e-10 -4.3 5.9 3.2e-09 0.27 0.04 0.96 FALSE
59 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DNA2 0.11 0.09 lasso 8 0.09 5.7e-10 -4.9 5.2 2.0e-07 0.28 0.94 0.06 FALSE
60 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PBLD 0.10 0.03 lasso 3 0.04 2.2e-05 -6.9 -6.6 4.8e-11 -0.31 0.01 0.99 FALSE
61 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma ATOH7 0.08 0.04 enet 19 0.06 3.1e-04 -4.3 6.5 6.4e-11 0.23 0.03 0.86 FALSE
62 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DNA2 0.05 0.00 blup 43 0.00 3.0e-01 -6.3 6.7 1.7e-11 0.38 0.01 0.85 FALSE
63 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PBLD 0.06 0.06 enet 6 0.06 2.5e-04 -5.7 -5.7 1.2e-08 -0.29 0.23 0.30 FALSE
64 The Cancer Genome Atlas Brain Lower Grade Glioma PBLD 0.12 0.18 enet 10 0.18 6.7e-20 -5.3 -6.2 6.0e-10 -0.34 0.34 0.66 FALSE
65 The Cancer Genome Atlas Brain Lower Grade Glioma SLC25A16 0.05 0.01 blup 42 0.02 2.9e-03 -6.3 -7.4 1.6e-13 -0.50 0.11 0.72 FALSE
66 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DNA2 0.08 0.05 blup 43 0.09 7.5e-05 -4.2 5.4 6.6e-08 0.30 0.02 0.90 FALSE
67 The Cancer Genome Atlas Lung Adenocarcinoma SLC25A16 0.03 0.03 lasso 2 0.02 1.4e-03 -6.3 -5.3 1.5e-07 -0.28 0.12 0.04 FALSE
68 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PBLD 0.02 0.01 blup 76 0.01 1.5e-02 -5.8 -5.4 5.8e-08 -0.27 0.15 0.23 FALSE
69 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC25A16 0.02 0.02 enet 8 0.02 7.7e-04 -8.1 -7.7 2.0e-14 -0.37 0.06 0.34 FALSE
70 The Cancer Genome Atlas Prostate Adenocarcinoma PBLD 0.03 0.01 blup 76 0.01 1.3e-02 -6.2 -6.3 3.3e-10 -0.29 0.06 0.36 FALSE
71 The Cancer Genome Atlas Prostate Adenocarcinoma SLC25A16 0.05 0.02 blup 42 0.05 5.5e-06 -3.5 -5.5 4.5e-08 -0.37 0.78 0.02 FALSE
72 The Cancer Genome Atlas Soft Tissue Sarcoma SLC25A16 0.07 0.03 blup 42 0.02 1.7e-02 -8.1 -8.8 9.0e-19 -0.53 0.08 0.45 TRUE
73 The Cancer Genome Atlas Testicular Germ Cell Tumors DNA2 0.14 0.07 blup 43 0.08 8.6e-04 -6.4 -6.8 8.7e-12 -0.38 0.08 0.45 FALSE
74 The Cancer Genome Atlas Thyroid Carcinoma PBLD 0.06 0.09 lasso 2 0.09 1.1e-08 -5.3 -5.4 5.4e-08 -0.28 0.61 0.39 FALSE
75 The Cancer Genome Atlas Thyroid Carcinoma SLC25A16 0.05 0.05 lasso 3 0.04 3.8e-05 -6.3 -6.5 7.3e-11 -0.35 0.25 0.23 FALSE