[Hub]/) : Traits : Trunk fat-free mass : ← →

chr10:123,438,113-124,889,817

Best TWAS P=1.76e-13 · Best GWAS P=3.54e-13 conditioned to 0.0228

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PLEKHA1 0.14 0.06 lasso 2 0.03 2.4e-03 6.6 -6.7 1.9e-11 0.76 0.15 0.79 FALSE
2 GTEx Muscle Skeletal PLEKHA1 0.10 0.04 lasso 3 0.04 8.2e-05 -7.2 -5.7 1.1e-08 0.86 0.02 0.98 FALSE
3 GTEx Nerve Tibial PLEKHA1 0.22 0.23 enet 17 0.19 1.1e-13 6.6 -5.9 3.7e-09 0.64 0.24 0.76 FALSE
4 GTEx Skin Sun Exposed Lower leg PLEKHA1 0.16 0.02 lasso 5 0.01 4.0e-02 -6.3 -6.7 2.3e-11 0.81 0.02 0.97 FALSE
5 METSIM Adipose PLEKHA1 0.05 0.03 lasso 4 0.04 3.6e-07 6.6 -7.4 1.8e-13 0.80 0.08 0.92 TRUE
6 ROSMAP Brain Pre-frontal Cortex PLEKHA1 0.06 0.05 lasso 4 0.05 1.3e-06 -7.1 -7.1 1.2e-12 0.99 0.01 0.99 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma PLEKHA1 0.04 0.05 lasso 2 0.04 4.3e-05 6.6 -6.6 4.1e-11 0.77 0.11 0.86 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ARMS2 0.23 0.20 lasso 2 0.21 7.0e-09 -5.6 -5.8 6.2e-09 0.65 0.88 0.06 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PLEKHA1 0.08 0.06 blup 103 0.02 4.0e-02 6.6 -5.7 1.4e-08 0.83 0.02 0.80 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma ARMS2 0.06 0.04 blup 71 0.05 4.9e-06 -7.1 -6.7 1.9e-11 0.81 0.00 1.00 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma PLEKHA1 0.08 0.10 lasso 1 0.09 3.5e-09 6.6 -6.5 5.7e-11 0.77 0.29 0.71 FALSE