[Hub]/) : Traits : Trunk fat-free mass : ← →

chr10:123,438,113-124,889,817

Best TWAS P=1.76e-13 · Best GWAS P=3.54e-13 conditioned to 0.0228

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	METSIM	Adipose	PLEKHA1	0.05	0.03	lasso	4	0.04	3.6e-07	6.6	-7.4	1.8e-13	0.80	0.08	0.92	TRUE
6	ROSMAP	Brain Pre-frontal Cortex	PLEKHA1	0.06	0.05	lasso	4	0.05	1.3e-06	-7.1	-7.1	1.2e-12	0.99	0.01	0.99	FALSE
1	GTEx	Adipose Subcutaneous	PLEKHA1	0.14	0.06	lasso	2	0.03	2.4e-03	6.6	-6.7	1.9e-11	0.76	0.15	0.79	FALSE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	ARMS2	0.06	0.04	blup	71	0.05	4.9e-06	-7.1	-6.7	1.9e-11	0.81	0.00	1.00	FALSE
4	GTEx	Skin Sun Exposed Lower leg	PLEKHA1	0.16	0.02	lasso	5	0.01	4.0e-02	-6.3	-6.7	2.3e-11	0.81	0.02	0.97	FALSE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	PLEKHA1	0.04	0.05	lasso	2	0.04	4.3e-05	6.6	-6.6	4.1e-11	0.77	0.11	0.86	FALSE
11	The Cancer Genome Atlas	Thyroid Carcinoma	PLEKHA1	0.08	0.10	lasso	1	0.09	3.5e-09	6.6	-6.5	5.7e-11	0.77	0.29	0.71	FALSE
3	GTEx	Nerve Tibial	PLEKHA1	0.22	0.23	enet	17	0.19	1.1e-13	6.6	-5.9	3.7e-09	0.64	0.24	0.76	FALSE
8	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ARMS2	0.23	0.20	lasso	2	0.21	7.0e-09	-5.6	-5.8	6.2e-09	0.65	0.88	0.06	FALSE
2	GTEx	Muscle Skeletal	PLEKHA1	0.10	0.04	lasso	3	0.04	8.2e-05	-7.2	-5.7	1.1e-08	0.86	0.02	0.98	FALSE
9	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	PLEKHA1	0.08	0.06	blup	103	0.02	4.0e-02	6.6	-5.7	1.4e-08	0.83	0.02	0.80	FALSE