[Hub]/) : Traits : Trunk fat-free mass :

chr16:13,697,975-15,886,243

Best TWAS P=3.21e-13 · Best GWAS P=1.01e-12 conditioned to 2.25e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NTAN1 0.05 0.03 lasso 2 0.04 6.7e-04 -6.5 6.9 4.9e-12 -0.12 0.01 0.97 FALSE
2 GTEx Artery Tibial RRN3 0.11 0.06 lasso 2 0.07 2.0e-06 5.4 5.2 2.3e-07 -0.14 0.81 0.16 FALSE
3 GTEx Cells EBV-transformed lymphocytes RRN3 0.36 0.14 lasso 5 0.20 4.5e-07 5.4 5.7 1.6e-08 -0.14 0.20 0.76 FALSE
4 GTEx Cells EBV-transformed lymphocytes RP11-958N24.1 0.22 0.02 lasso 5 0.06 4.8e-03 -3.1 5.4 7.9e-08 -0.14 0.02 0.37 FALSE
5 GTEx Cells Transformed fibroblasts RRN3 0.10 0.12 enet 13 0.13 6.3e-10 5.4 6.1 1.3e-09 -0.15 0.67 0.33 FALSE
6 GTEx Colon Transverse RRN3 0.13 0.00 lasso 5 0.00 1.9e-01 5.2 -5.2 1.7e-07 0.11 0.03 0.31 FALSE
7 GTEx Heart Atrial Appendage NOMO1 0.19 0.12 lasso 6 0.10 3.7e-05 5.2 5.1 2.8e-07 -0.15 0.22 0.28 FALSE
8 GTEx Heart Atrial Appendage NTAN1 0.10 0.09 lasso 1 0.07 3.7e-04 5.2 5.2 2.2e-07 -0.14 0.04 0.45 FALSE
9 GTEx Heart Left Ventricle RRN3 0.24 0.12 lasso 7 0.17 2.2e-09 5.2 -6.0 2.7e-09 0.11 0.55 0.36 FALSE
10 GTEx Heart Left Ventricle NTAN1 0.09 0.04 lasso 3 0.02 2.0e-02 5.4 5.3 1.1e-07 -0.14 0.02 0.71 FALSE
11 GTEx Muscle Skeletal RRN3 0.18 0.03 enet 17 0.11 5.7e-11 4.0 -5.7 9.9e-09 0.09 0.18 0.70 FALSE
12 GTEx Muscle Skeletal NTAN1 0.12 0.07 lasso 6 0.09 1.4e-09 5.2 5.8 8.9e-09 -0.13 0.85 0.14 FALSE
13 GTEx Nerve Tibial NTAN1 0.07 0.00 enet 14 0.00 1.7e-01 5.4 6.1 1.4e-09 -0.05 0.02 0.18 FALSE
14 GTEx Skin Sun Exposed Lower leg RRN3 0.10 0.12 lasso 1 0.11 4.5e-09 5.4 5.4 6.1e-08 -0.14 0.80 0.19 FALSE
15 GTEx Testis RRN3 0.10 0.10 lasso 2 0.07 3.9e-04 5.4 5.4 6.1e-08 -0.14 0.11 0.14 FALSE
16 GTEx Thyroid RP11-65J21.3 0.35 0.32 lasso 2 0.31 2.6e-24 -5.9 -5.9 3.2e-09 -0.54 0.84 0.16 TRUE
17 NTR Blood NTAN1 0.01 0.00 bslmm 110 0.00 4.2e-02 5.4 6.0 1.9e-09 -0.09 0.02 0.04 FALSE
18 NTR Blood PDXDC1 0.12 0.12 enet 26 0.15 1.3e-46 -6.5 7.3 3.2e-13 -0.14 0.01 0.99 TRUE
19 ROSMAP Brain Pre-frontal Cortex NTAN1 0.12 0.10 lasso 3 0.11 1.4e-13 5.2 5.3 1.4e-07 -0.14 0.90 0.10 FALSE