[Hub]/) : Traits : Trunk fat-free mass : ← →

chr16:19,022,448-21,352,507

Best TWAS P=9.52e-12 · Best GWAS P=1.16e-11 conditioned to 2.34e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	GPRC5B	0.07	0.04	lasso	4	0.03	1.3e-03	-6.1	6.8	9.5e-12	0.31	0.20	0.50	TRUE
4	GTEx	Cells Transformed fibroblasts	THUMPD1	0.13	0.16	enet	16	0.16	4.2e-12	-5.3	-5.5	3.5e-08	0.04	0.02	0.98	TRUE
14	The Cancer Genome Atlas	Thyroid Carcinoma	GPRC5B	0.06	0.01	blup	38	0.01	2.4e-02	-3.9	-6.1	9.5e-10	-0.43	0.01	0.10	FALSE
10	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IQCK	0.03	0.03	lasso	3	0.02	7.2e-04	-5.4	-5.7	1.6e-08	-0.25	0.04	0.91	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	ACSM3	0.06	0.04	blup	43	0.03	5.9e-04	-5.4	5.5	3.6e-08	-0.05	0.01	0.96	FALSE
11	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	THUMPD1	0.04	0.04	blup	30	0.03	2.3e-03	-5.3	-5.5	4.5e-08	0.03	0.01	0.85	FALSE
7	GTEx	Testis	AC004381.6	0.18	0.10	lasso	7	0.08	1.8e-04	-5.4	-5.5	4.9e-08	0.04	0.02	0.95	FALSE
6	GTEx	Esophagus Gastroesophageal Junction	AC002550.5	0.62	0.54	enet	35	0.63	4.4e-29	-3.8	-5.4	6.5e-08	-0.27	1.00	0.00	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	ACSM3	0.06	0.06	lasso	13	0.05	2.8e-06	-5.3	5.3	1.0e-07	-0.04	0.01	0.98	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	KNOP1	0.51	0.44	enet	22	0.56	5.3e-24	-4.7	-5.3	1.1e-07	-0.27	0.92	0.08	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	THUMPD1	0.08	0.12	enet	24	0.12	3.0e-15	-5.3	5.3	1.4e-07	-0.03	0.02	0.98	FALSE
8	METSIM	Adipose	ACSM1	0.05	0.05	lasso	5	0.06	9.5e-09	-5.3	-5.2	1.8e-07	0.05	0.03	0.97	FALSE
2	GTEx	Brain Putamen basal ganglia	AC002550.5	0.59	0.48	enet	23	0.58	1.2e-16	-3.9	-5.2	2.0e-07	-0.19	1.00	0.00	FALSE
3	GTEx	Breast Mammary Tissue (Male)	AC002550.5	0.37	0.29	lasso	3	0.35	4.8e-09	-5.3	-5.1	3.1e-07	-0.22	0.72	0.20	FALSE