TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Trunk fat-free mass
:
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chr17:1,588,930-3,000,009
Best TWAS P=3.34e-10 · Best GWAS P=5e-10 conditioned to 0.000191
1.6M
1.8M
2M
2.2M
2.4M
2.6M
2.8M
3M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
SMG6
0.03
0.01
blup
144
0.01
4.8e-03
4.4
6.3
3.3e-10
-0.46
0.16
0.34
TRUE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SMG6
0.08
0.05
blup
144
0.07
1.3e-04
5.2
6.0
2.7e-09
-0.50
0.35
0.44
FALSE
1
ROSMAP
Brain Pre-frontal Cortex
MNT
0.09
0.04
lasso
5
0.06
9.5e-09
-5.2
5.4
8.0e-08
-0.43
0.74
0.26
FALSE