Best TWAS P=3.34e-10 · Best GWAS P=5e-10 conditioned to 0.000191
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | MNT | 0.09 | 0.04 | lasso | 5 | 0.06 | 9.5e-09 | -5.2 | 5.4 | 8.0e-08 | -0.43 | 0.74 | 0.26 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMG6 | 0.03 | 0.01 | blup | 144 | 0.01 | 4.8e-03 | 4.4 | 6.3 | 3.3e-10 | -0.46 | 0.16 | 0.34 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SMG6 | 0.08 | 0.05 | blup | 144 | 0.07 | 1.3e-04 | 5.2 | 6.0 | 2.7e-09 | -0.50 | 0.35 | 0.44 | FALSE |