Best TWAS P=1.94e-07 · Best GWAS P=4.7e-07 conditioned to 0.107
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | RPAIN | 0.06 | 0.06 | lasso | 3 | 0.06 | 3.1e-08 | 5.0 | -5.2 | 2.1e-07 | -0.98 | 0.00 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Glioblastoma Multiforme | RABEP1 | 0.23 | 0.13 | blup | 79 | 0.15 | 3.4e-05 | 4.3 | -5.2 | 1.9e-07 | -0.77 | 0.04 | 0.79 | TRUE |