[Hub]/) : Traits : Trunk fat-free mass :

chr19:56,320,200-58,650,058

Best TWAS P=1.76e-08 · Best GWAS P=1.09e-07 conditioned to 0.00435

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta AC007228.11 0.31 0.22 enet 24 0.23 6.5e-13 5.3 5.4 7.5e-08 0.90 0.00 0.99 FALSE
2 GTEx Brain Cerebellum ZNF471 0.24 0.25 enet 14 0.20 1.2e-06 4.2 -5.3 1.2e-07 -0.68 0.14 0.79 FALSE
3 GTEx Brain Hypothalamus AC007228.11 0.39 0.24 lasso 6 0.22 8.8e-06 5.3 5.4 5.8e-08 0.96 0.01 0.98 FALSE
4 GTEx Cells Transformed fibroblasts ZNF304 0.25 0.15 lasso 3 0.18 1.0e-13 5.1 -5.2 2.1e-07 0.04 0.01 0.98 FALSE
5 GTEx Colon Sigmoid AC007228.11 0.21 0.19 lasso 3 0.15 7.9e-06 5.3 5.3 1.3e-07 1.00 0.01 0.99 FALSE
6 GTEx Ovary AC007228.11 0.29 0.04 lasso 7 0.12 6.6e-04 5.3 5.4 7.1e-08 0.92 0.02 0.87 FALSE
7 GTEx Skin Sun Exposed Lower leg ZNF749 0.16 0.10 lasso 3 0.11 3.3e-09 4.7 5.2 2.0e-07 -0.06 0.01 0.98 FALSE
8 GTEx Skin Sun Exposed Lower leg ZFP28 0.19 0.13 lasso 9 0.17 1.1e-13 5.3 5.4 8.4e-08 0.93 0.01 0.99 FALSE
9 GTEx Spleen AC007228.11 0.25 0.08 enet 23 0.07 6.0e-03 -4.4 5.2 2.0e-07 0.72 0.04 0.79 FALSE
10 METSIM Adipose ZFP28 0.13 0.09 bslmm 490 0.12 7.3e-17 4.4 5.3 1.2e-07 0.79 0.02 0.98 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma ZNF470 0.05 0.02 blup 73 0.04 3.1e-03 -4.0 5.5 4.7e-08 0.70 0.02 0.50 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ZNF470 0.06 0.02 blup 72 0.03 1.8e-04 -4.3 5.6 1.8e-08 0.61 0.06 0.92 TRUE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ZNF749 0.26 0.15 enet 6 0.18 6.0e-12 5.0 -5.4 5.3e-08 0.07 0.01 0.99 TRUE
14 The Cancer Genome Atlas Stomach Adenocarcinoma ZNF71 0.07 0.05 blup 78 0.02 1.6e-02 -4.0 5.2 1.9e-07 0.48 0.02 0.66 FALSE