[Hub]/) : Traits : Trunk fat-free mass : ← →

chr20:19,318,837-22,188,798

Best TWAS P=2.65e-19 · Best GWAS P=7.39e-21 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	PLK1S1	0.07	0.08	enet	10	0.08	4.0e-07	9.3	9.0	2.6e-19	0.97	0.01	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	C20orf26	0.20	0.17	lasso	6	0.18	4.9e-21	-6.4	6.2	4.8e-10	-0.06	0.38	0.62	TRUE
12	ROSMAP	Brain Pre-frontal Cortex	INSM1	0.19	0.10	lasso	5	0.14	4.3e-17	3.3	5.3	1.3e-07	0.07	1.00	0.00	TRUE
19	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PLK1S1	0.09	0.02	blup	64	0.05	3.1e-03	7.7	8.3	8.3e-17	0.78	0.03	0.53	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	PLK1S1	0.04	0.03	blup	64	0.04	4.0e-05	7.4	8.3	8.8e-17	0.88	0.12	0.87	FALSE
10	GTEx	Whole Blood	PLK1S1	0.08	0.04	enet	9	0.02	4.0e-03	7.4	8.1	7.2e-16	0.89	0.06	0.94	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	PLK1S1	0.21	0.09	lasso	6	0.12	5.3e-07	9.0	7.9	3.1e-15	0.93	0.06	0.93	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	PLK1S1	0.05	0.07	enet	9	0.07	5.5e-15	7.1	7.8	7.4e-15	0.88	0.16	0.84	FALSE
9	GTEx	Testis	PLK1S1	0.64	0.34	enet	33	0.39	1.0e-18	7.4	7.7	1.5e-14	0.79	0.65	0.35	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	PLK1S1	0.06	0.04	lasso	3	0.04	1.5e-04	7.4	7.6	3.9e-14	0.85	0.16	0.59	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLK1S1	0.19	0.12	enet	14	0.13	4.3e-13	7.4	7.4	1.0e-13	0.80	0.91	0.09	FALSE
5	GTEx	Esophagus Mucosa	PLK1S1	0.11	0.11	lasso	5	0.09	7.8e-07	7.3	7.3	3.5e-13	0.83	0.12	0.87	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PLK1S1	0.08	0.01	lasso	3	0.04	1.1e-05	7.7	7.2	5.3e-13	0.82	0.02	0.98	FALSE
8	GTEx	Skin Sun Exposed Lower leg	PLK1S1	0.15	0.13	enet	10	0.15	3.9e-12	7.4	7.0	2.8e-12	0.83	0.92	0.08	FALSE
6	GTEx	Heart Atrial Appendage	PLK1S1	0.15	-0.01	lasso	4	0.00	6.1e-01	1.1	6.2	4.0e-10	0.56	0.05	0.40	FALSE
13	YFS	Blood	CRNKL1	0.21	0.25	enet	18	0.27	2.3e-89	-6.4	-6.2	6.3e-10	0.03	0.34	0.66	FALSE
2	CommonMind	Brain Pre-frontal Cortex	INSM1	0.07	0.00	bslmm	522	0.02	2.2e-03	4.3	6.2	6.7e-10	-0.01	0.09	0.08	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	NKX2-2	0.11	0.06	lasso	5	0.06	2.3e-08	5.0	-5.6	1.9e-08	-0.61	1.00	0.00	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NAA20	0.04	0.01	enet	11	0.02	7.6e-04	-6.9	-5.6	2.6e-08	0.03	0.01	0.62	FALSE
14	YFS	Blood	XRN2	0.34	0.61	lasso	10	0.61	3.5e-258	5.5	5.5	3.2e-08	0.49	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	NKX2-2	0.02	0.03	lasso	4	0.02	1.0e-03	5.0	-5.3	1.2e-07	-0.57	0.03	0.70	FALSE