Best TWAS P=9.22e-09 · Best GWAS P=8.83e-07 conditioned to 0.853
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MST1P9 | 0.31 | 0.09 | blup | 38 | 0.14 | 2.3e-27 | -3.8 | -5.2 | 2.3e-07 | 0.70 | 0.12 | 0.62 | FALSE |
| 2 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | MST1P9 | 0.11 | 0.11 | blup | 38 | 0.08 | 1.3e-04 | -4.9 | -5.7 | 1.5e-08 | 0.93 | 0.00 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | MFAP2 | 0.12 | 0.06 | blup | 38 | 0.07 | 4.3e-05 | -4.7 | 5.3 | 8.7e-08 | -0.85 | 0.01 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MST1P9 | 0.15 | 0.13 | enet | 15 | 0.13 | 1.5e-14 | -4.7 | -5.3 | 1.0e-07 | 0.92 | 0.00 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | MFAP2 | 0.17 | 0.22 | enet | 10 | 0.23 | 6.8e-26 | -4.9 | 5.2 | 1.7e-07 | -0.95 | 0.00 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MST1P9 | 0.15 | 0.13 | enet | 14 | 0.17 | 6.2e-19 | -4.9 | -5.7 | 9.2e-09 | 0.84 | 0.00 | 0.99 | TRUE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | MFAP2 | 0.04 | 0.03 | blup | 38 | 0.03 | 6.7e-05 | -4.7 | 5.4 | 6.2e-08 | -0.83 | 0.00 | 0.95 | FALSE |
| 8 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | MST1P9 | 0.08 | 0.05 | blup | 38 | 0.08 | 4.2e-06 | 4.2 | -5.3 | 9.0e-08 | 0.84 | 0.01 | 0.90 | FALSE |
| 9 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | ATP13A2 | 0.14 | 0.05 | blup | 54 | 0.08 | 2.5e-04 | -3.6 | 5.2 | 2.7e-07 | -0.82 | 0.01 | 0.72 | FALSE |