TWAS hub - MFAP2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.2420	0.0730	2.4e-05	0.038	NA	0.032	NA	0.040	3.6e-03	NA	7.2e-03	NA	3.0e-03
2	GTEx	Artery Tibial	0.1495	0.0544	2.5e-05	0.056	NA	0.073	NA	0.055	3.4e-05	NA	2.3e-06	NA	4.0e-05
3	GTEx	Brain Caudate basal ganglia	0.1390	0.0630	7.0e-03	0.029	NA	0.007	NA	0.000	5.1e-02	NA	2.0e-01	NA	3.2e-01
4	GTEx	Cells Transformed fibroblasts	0.2920	0.0530	0.0e+00	0.392	NA	0.417	NA	0.405	3.6e-31	NA	1.3e-33	NA	2.2e-32
5	GTEx	Esophagus Muscularis	0.1410	0.0470	4.6e-05	0.154	NA	0.118	NA	0.121	1.3e-09	NA	1.2e-07	NA	8.8e-08
6	GTEx	Lung	0.0891	0.0335	6.6e-05	0.078	NA	0.063	NA	-0.002	1.5e-06	NA	1.3e-05	NA	5.6e-01
7	GTEx	Nerve Tibial	0.0943	0.0333	5.3e-05	0.063	NA	0.066	NA	0.071	3.2e-05	NA	1.8e-05	NA	9.7e-06
8	TCGA	Breast Invasive Carcinoma	0.0378	0.0182	4.6e-07	0.026	0.029	0.025	NA	0.021	4.3e-06	1.1e-06	5.0e-06	NA	2.6e-05
9	TCGA	Colon Adenocarcinoma	0.1190	0.0560	2.5e-05	0.058	0.074	0.066	NA	0.067	2.8e-04	4.3e-05	1.2e-04	NA	9.8e-05
10	TCGA	Glioblastoma Multiforme	0.1850	0.1070	3.1e-03	0.073	0.056	0.068	NA	0.050	3.0e-03	8.7e-03	4.1e-03	NA	1.3e-02
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.0996	0.0554	3.6e-07	0.053	0.063	0.067	NA	0.055	1.2e-06	1.2e-07	5.7e-08	NA	7.8e-07
12	TCGA	Kidney Renal Clear Cell Carcinoma	0.1708	0.0515	0.0e+00	0.222	0.224	0.233	NA	0.168	1.4e-24	7.3e-25	6.7e-26	NA	1.5e-18
13	TCGA	Brain Lower Grade Glioma	0.0218	0.0137	5.4e-03	0.023	0.019	0.019	NA	0.019	1.0e-03	2.7e-03	3.0e-03	NA	2.4e-03
14	TCGA	Lung Adenocarcinoma	0.0440	0.0220	7.7e-05	0.030	0.034	0.028	NA	0.022	1.8e-04	6.7e-05	2.5e-04	NA	1.1e-03
15	TCGA	Lung Squamous Cell Carcinoma	0.0399	0.0205	1.4e-04	0.019	0.032	0.008	NA	0.026	2.8e-03	1.5e-04	3.6e-02	NA	5.8e-04
16	TCGA	Prostate Adenocarcinoma	0.0577	0.0249	2.5e-06	0.037	0.050	0.046	NA	0.041	8.4e-05	5.2e-06	1.4e-05	NA	3.6e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Lung FEV1/FVC ratio	45.6	231.2	334.9	-13.5	-15.8	-14.7	-15.1	-16.0	-17.2	-15.8	-14.6	-16.3	-12.9	-13.4	-18.3	-13.9	-16.5	-14.8	-13.3
Forced vital capacity (FVC), Best measure	26.6	97.5	141.6	9.9	10.0	9.6	9.1	10.3	10.3	10.8	9.2	10.8	8.3	8.8	11.9	7.8	11.0	9.9	9.5
Forced vital capacity (FVC)	24.3	93.6	134.6	9.3	9.8	9.3	9.2	10.2	10.5	10.6	8.8	10.6	8.2	8.5	11.6	8.1	10.4	9.8	9.3
Height	23.9	461.3	620.0	19.1	20.3	19.7	21.1	22.6	22.8	21.7	21.2	24.8	19.3	20.4	24.9	19.0	24.0	21.8	19.6
Standing height	19.6	194.2	265.7	13.2	12.9	13.4	13.1	14.9	15.1	14.5	13.2	16.3	12.2	13.1	16.3	11.9	15.7	13.6	12.5
Comparative height size at age 10	16.7	91.8	123.2	9.5	8.7	9.1	9.6	10.1	10.2	10.0	9.5	10.6	8.1	8.6	11.1	8.8	10.7	9.5	8.7
Lung FVC	15.3	77.9	99.2	8.5	9.1	7.5	9.0	9.5	9.0	10.0	8.7	8.5	6.9	8.5	9.8	7.9	9.0	9.5	9.3
Forced expiratory volume in 1-second (FEV1), predicted	12.7	26.4	49.3	4.4	4.7	5.0	4.3	5.7	5.4	5.0	4.3	7.0	3.8	5.3	6.5	3.7	5.9	5.1	4.8
Sitting height	11.7	83.4	125.4	8.3	7.9	8.5	8.5	10.0	9.9	9.4	8.4	11.2	8.5	8.8	10.8	7.6	10.4	8.8	8.2
Rheumatoid Arthritis	8.5	11.8	19.3	3.1	3.4	3.8	3.5	3.2	4.4	3.3	3.0	3.8	2.0	4.4	3.5	3.6	2.6	3.5	3.1
Ovarian Cancer	7.4	9.8	13.9	-2.7	-2.8	-2.3	-3.5	-2.9	-2.6	-3.3	-3.5	-3.6	-2.5	-3.5	-3.1	-3.4	-3.1	-3.7	-3.2
Forced expiratory volume in 1-second (FEV1), Best measure	7.0	22.2	31.3	5.3	4.7	4.6	3.8	4.9	4.5	5.5	4.1	5.1	3.9	4.0	5.6	2.9	5.3	5.0	5.2
Forced expiratory volume in 1-second (FEV1)	6.7	22.5	30.8	4.9	4.8	4.5	4.3	4.9	4.8	5.5	4.0	5.1	4.3	4.2	5.6	3.6	5.0	5.1	5.1
Impedance of arm (left)	6.7	30.9	39.1	4.0	5.6	5.3	5.1	5.8	6.1	6.0	5.2	6.2	4.6	6.0	6.0	5.2	5.7	5.9	5.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	6.6	7.8	12.3	-3.5	-2.1	-3.0	-2.6	-2.8	-3.2	-2.8	-2.6	-3.0	-2.0	-2.5	-3.0	-1.9	-3.1	-3.0	-3.0
Impedance of arm (right)	6.5	30.3	40.3	4.1	5.4	5.3	5.2	5.7	6.2	5.7	5.1	6.3	4.5	5.7	6.0	5.3	5.6	5.8	5.5
Ever highly irritable/argumentative for 2 days	6.4	7.6	12.5	-1.9	-2.1	-1.7	-2.8	-2.4	-2.0	-2.3	-3.3	-3.5	-2.6	-3.0	-3.1	-3.1	-3.5	-3.1	-2.9
Impedance of whole body	6.4	32.6	41.6	4.3	6.3	5.5	5.3	6.1	6.5	6.2	5.2	6.3	4.0	6.0	6.4	5.4	5.6	6.0	5.7
Impedance of leg (right)	6.1	29.5	40.3	4.4	6.3	5.1	5.3	5.5	6.0	5.8	5.0	5.8	2.7	5.8	6.2	5.6	4.9	5.8	5.4
Impedance of leg (left)	5.1	25.0	38.9	3.8	6.2	4.8	4.6	5.2	5.7	5.4	4.3	5.4	2.8	5.3	5.9	4.8	4.6	5.1	4.7
Heart disease (siblings)	4.6	5.7	9.2	2.0	2.5	2.1	2.4	3.0	3.0	1.7	2.1	2.8	1.6	2.3	3.0	2.4	2.6	2.0	1.6
Waist Hip Ratio (WHR)	4.5	20.2	34.1	4.2	5.1	5.0	5.8	4.3	5.5	5.2	4.6	3.5	1.1	4.0	5.3	5.3	3.8	3.8	2.7
Hand grip strength (right)	4.2	11.3	19.2	2.8	4.1	2.6	2.9	4.2	3.9	3.1	3.1	4.4	2.5	2.6	4.2	2.4	4.2	3.0	2.6
Frequency of depressed mood in last 2 weeks	4.1	5.8	10.0	-1.9	-2.5	-1.2	-2.6	-2.5	-1.8	-3.0	-2.8	-2.0	-3.2	-2.0	-2.8	-2.0	-2.8	-2.4	-2.3
LDL Cholesterol	4.0	6.3	11.6	0.5	1.5	3.0	2.4	2.3	2.5	2.4	3.4	3.0	2.5	3.2	2.4	2.4	3.2	2.3	1.8
Average weekly fortified wine intake	4.0	4.7	10.0	2.1	0.7	2.5	2.4	1.9	1.5	1.8	2.9	2.1	2.5	1.0	3.1	2.5	3.2	1.7	1.1
Average weekly red wine intake	3.6	5.3	8.1	1.7	2.3	2.2	2.8	2.2	2.4	2.3	2.6	2.1	1.3	2.0	2.7	2.8	2.1	2.6	2.2
Trunk fat-free mass	3.5	19.9	29.3	4.8	3.3	4.1	4.4	4.7	4.7	4.4	4.4	5.3	4.2	4.0	5.2	3.6	5.4	4.2	3.9
BMI	3.4	20.0	33.2	-4.4	-4.5	-4.0	-3.0	-4.9	-4.7	-4.7	-3.1	-5.8	-3.8	-4.5	-5.5	-2.6	-4.6	-4.8	-5.2
Trunk predicted mass	3.4	19.2	28.2	4.8	3.2	4.0	4.3	4.6	4.6	4.3	4.3	5.2	4.1	3.9	5.2	3.5	5.3	4.2	3.8
Ever had prostate specific antigen (PSA) test	3.3	3.8	6.4	2.2	1.4	1.8	1.9	1.6	2.4	1.7	1.9	2.0	2.5	1.4	2.4	1.9	2.2	1.8	1.5
Alzheimer’s Disease (including proxy)	3.1	4.5	7.5	-1.9	-2.7	-2.7	-2.5	-2.1	-2.6	-2.5	-1.4	-1.6	-0.3	-2.1	-2.4	-2.6	-1.4	-1.7	-1.6
Hair/balding pattern: Pattern 3	3.1	4.7	6.9	-1.3	-2.5	-2.2	-2.6	-1.8	-2.5	-2.1	-2.1	-2.3	-1.8	-1.3	-2.3	-2.6	-2.1	-2.6	-1.9
Alcohol usually taken with meals	3.0	4.8	7.5	1.8	1.6	0.9	2.4	2.6	1.6	2.3	2.6	2.1	1.8	2.2	2.4	2.2	2.4	2.6	2.7
Length of working week for main job	3.0	3.3	5.9	-2.2	-2.1	-0.7	-0.8	-1.7	-1.4	-1.9	-1.7	-2.1	-2.1	-2.4	-2.0	-0.7	-2.0	-1.7	-2.0
Leg pain on walking	2.9	3.7	5.3	-2.2	-1.9	-1.8	-2.0	-1.6	-1.8	-1.7	-2.1	-2.3	-0.9	-1.8	-2.1	-1.9	-2.0	-2.2	-1.9
Deep venous thrombosis (DVT) (self-reported)	2.9	3.8	6.1	1.2	1.7	1.6	2.5	1.9	2.2	1.9	2.0	2.4	1.2	2.2	1.9	2.3	1.7	2.1	1.7
Body Mass Index (BMI) (2010)	2.8	3.9	6.4	-2.5	-1.9	-1.3	-2.2	-1.6	-2.1	-2.0	-2.1	-1.7	-1.2	-1.9	-2.0	-2.3	-1.5	-2.3	-2.1
Vitamin and mineral supplements	2.8	3.8	7.7	1.1	0.7	1.8	1.6	2.2	1.5	1.7	2.6	2.4	2.5	2.0	1.6	1.7	2.8	2.2	1.9
Hand grip strength (left)	2.7	7.2	14.5	2.1	2.5	2.2	2.3	3.6	2.6	2.7	2.4	3.8	1.3	2.1	3.2	1.8	3.4	2.8	2.7
Peak expiratory flow (PEF)	2.6	6.0	9.3	-2.5	-2.1	-2.4	-2.6	-2.6	-3.0	-2.1	-2.6	-2.8	-1.5	-2.1	-2.9	-2.7	-2.8	-2.1	-1.5
Chronic bronchitis/emphysema (mother)	2.6	3.1	4.6	-2.1	-1.6	-1.2	-1.5	-1.4	-2.0	-1.5	-2.0	-1.9	-2.1	-1.3	-2.1	-1.5	-2.0	-1.7	-1.5
Medication: Seretide 50 evohaler	2.6	3.0	5.5	1.2	2.3	0.7	1.8	2.1	2.1	1.5	1.9	1.5	1.4	1.1	2.1	1.6	1.9	1.8	1.8
Whole body fat-free mass	2.6	14.8	22.9	4.2	2.6	3.5	3.9	4.0	4.0	3.9	3.9	4.6	3.7	3.1	4.4	3.1	4.8	3.7	3.3
Hip circumference	2.5	10.7	18.7	3.0	2.2	2.9	4.0	3.5	2.8	3.7	4.3	2.8	2.4	2.8	3.2	3.7	4.0	3.4	3.0
Arm predicted mass (right)	2.5	12.8	18.9	4.0	3.0	3.1	3.8	3.7	3.8	3.8	3.9	3.9	2.8	2.9	4.2	3.0	4.3	3.5	3.0
Whole body water mass	2.5	14.1	22.2	4.2	2.5	3.5	3.8	3.9	3.9	3.8	3.8	4.5	3.7	3.0	4.4	3.0	4.7	3.5	3.2
Basal metabolic rate	2.5	13.7	21.7	4.0	2.4	3.5	3.8	3.9	3.9	3.8	3.9	4.3	3.4	3.0	4.2	3.1	4.7	3.6	3.2
Alzheimer’s Disease (in father)	2.4	2.6	5.2	-2.0	-2.3	-1.5	-2.0	-1.8	-1.2	-1.7	-1.5	-1.3	-0.5	-0.8	-2.0	-1.7	-1.5	-1.4	-1.4
Mouth/teeth dental problems: Loose teeth	2.4	2.9	5.6	-2.4	-1.7	-1.2	-1.7	-1.6	-1.5	-1.7	-1.4	-1.7	-2.3	-1.7	-2.0	-1.7	-1.5	-1.4	-1.2
Financial situation satisfaction	2.4	3.0	5.3	-2.1	-2.2	-0.8	-1.4	-1.8	-1.9	-2.1	-1.0	-1.6	-1.4	-2.3	-1.9	-1.0	-1.4	-1.8	-2.0
Major Depression (MDD)	2.3	2.7	5.9	2.4	1.4	1.3	1.1	1.9	1.2	1.9	1.6	2.0	0.0	0.0	2.2	0.6	2.1	1.8	2.4
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.2	11.1	-2.0	-2.2	-1.6	-2.6	-2.2	-1.7	-2.1	-2.4	-2.1	-2.8	-3.3	-1.6	-2.7	-1.8	-2.6	-2.3
Blood Red Count	2.2	21.0	33.8	3.6	5.2	4.7	4.4	4.6	5.8	5.3	3.9	4.8	2.0	4.6	5.1	4.1	4.1	4.9	4.9
Body mass index (BMI)	2.2	9.2	16.8	-3.0	-3.5	-2.8	-1.9	-3.0	-3.5	-2.8	-1.9	-4.1	-3.0	-3.3	-3.9	-1.8	-3.0	-2.9	-2.9
Illnesses of siblings	2.2	3.1	6.1	-0.7	-1.9	-2.1	-1.9	-1.6	-1.9	-1.4	-1.7	-1.8	-2.5	-1.7	-2.1	-2.1	-2.0	-0.8	-0.3
Weight	2.2	10.8	16.3	2.9	2.2	3.2	3.9	3.7	3.3	3.7	3.9	3.2	2.5	2.6	3.4	3.4	4.0	3.2	2.8
Arm fat-free mass (right)	2.2	11.4	17.3	3.8	2.5	3.0	3.5	3.5	3.4	3.5	3.6	3.7	3.1	2.8	4.0	2.8	4.2	3.3	2.9
Arm predicted mass (left)	2.2	11.2	17.2	3.9	2.3	3.2	3.5	3.5	3.5	3.4	3.5	3.9	2.8	2.6	4.0	2.9	4.2	3.1	2.6
Ulcerative Colitis (UC)	2.1	4.0	7.1	1.9	2.1	1.0	1.6	1.9	2.7	1.9	2.0	2.2	1.7	2.3	1.6	1.2	1.9	2.5	2.5
Had major operations	2.1	2.5	4.9	2.0	1.6	1.8	1.2	1.8	2.0	1.7	1.1	1.5	0.9	1.8	2.2	0.8	1.7	1.2	1.4
Loneliness, isolation	2.1	2.9	6.2	-0.8	-0.8	-1.8	-0.9	-1.4	-1.9	-1.9	-2.0	-2.1	-0.9	-2.5	-1.9	-0.7	-2.3	-1.7	-1.9
Arm fat-free mass (left)	2.1	10.7	16.8	3.5	2.3	3.0	3.5	3.5	3.5	3.3	3.6	3.8	2.7	2.6	3.8	2.9	4.1	3.1	2.7
Commuting to job workplace: Cycle	2.1	2.5	6.9	1.1	0.0	1.4	1.4	1.2	1.1	2.1	2.0	1.1	1.3	1.6	0.8	1.4	1.5	2.6	2.6
Schizophrenia (2014)	2.0	4.3	8.0	-1.6	-1.4	-2.8	-2.8	-1.8	-2.1	-2.8	-2.2	-1.5	-0.7	-1.6	-2.6	-2.7	-1.9	-1.8	-1.6
Tinnitus: Yes, but not now, but have in the past	2.0	2.2	3.9	-1.8	-1.6	-1.3	-1.9	-1.2	-1.4	-1.8	-1.4	-0.9	0.2	-1.4	-1.1	-1.9	-0.7	-2.0	-1.8
Waist circumference	2.0	7.2	14.7	2.5	1.8	3.0	3.8	2.9	2.8	3.4	3.5	1.7	0.6	2.1	2.6	3.4	2.8	2.5	1.9
Blood clot in the leg (DVT)	2.0	2.6	4.7	0.9	1.2	1.5	2.0	1.4	2.0	1.5	1.6	2.2	1.2	2.1	1.6	1.9	1.4	1.6	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.0	4.2	8.7	2.6	2.3	2.3	2.0	1.9	1.8	2.9	1.5	1.3	1.9	1.4	2.0	1.5	1.6	2.3	2.3
Cholesterol lowering medication	2.0	3.0	5.8	0.7	1.1	1.9	2.0	2.4	2.3	2.2	1.9	1.7	0.6	1.3	1.2	1.8	1.8	1.8	1.6
Ulcerative Colitis	1.9	2.8	5.4	1.0	2.0	0.9	1.5	1.7	2.3	1.5	1.6	2.1	1.9	2.0	1.6	1.2	1.6	1.7	1.5
Trunk fat mass	1.9	8.1	14.1	1.8	2.2	2.6	3.8	3.2	3.0	3.3	3.6	2.3	2.0	2.1	2.7	3.6	3.3	2.8	2.3
Medication: Cholesterol lowering	1.9	3.0	5.8	-1.5	-1.8	-1.3	-0.5	-2.2	-1.9	-1.4	-1.1	-2.4	-2.3	-1.6	-2.2	-0.4	-2.2	-1.6	-1.8
Qualifications: nursing, teaching	1.9	3.0	6.2	2.1	0.5	0.9	2.1	1.4	1.2	1.5	2.5	1.1	1.7	1.2	1.3	2.1	1.9	2.4	2.1
Risk taking	1.9	2.7	5.4	1.5	1.8	1.1	2.2	1.8	2.0	1.0	2.0	1.5	0.6	1.2	1.8	2.3	1.6	1.8	1.2
Neuroticism (2016)	1.8	2.6	6.0	-1.9	-2.1	-2.5	-1.2	-1.3	-2.0	-1.8	-1.1	-1.1	-1.9	-1.5	-1.9	-0.7	-1.6	-1.1	-1.0
Heel T-Score	1.8	14.4	21.2	-3.3	-2.9	-4.0	-3.5	-3.8	-3.3	-3.6	-4.5	-4.6	-3.3	-3.9	-3.7	-3.1	-4.5	-4.4	-3.9
Angina	1.8	2.4	5.3	-2.0	-0.7	-0.5	-0.2	-1.3	-0.9	-1.2	-0.6	-2.1	-2.3	-2.1	-1.8	0.1	-1.8	-1.8	-2.3
Leg fat-free mass (left)	1.8	9.7	16.3	3.6	1.6	3.0	3.2	3.2	3.2	3.2	3.3	3.6	3.0	2.2	3.4	2.6	4.0	3.0	2.7
Serious illness, injury or assault to yourself	1.8	2.2	4.4	2.0	1.9	0.5	1.3	1.4	1.9	0.9	1.7	1.1	2.1	0.4	1.8	1.3	2.1	1.0	0.7
Leg predicted mass (left)	1.8	9.7	16.3	3.5	1.6	3.0	3.2	3.2	3.2	3.2	3.3	3.6	3.0	2.3	3.4	2.5	4.0	3.0	2.8
Bipolar Disorder or Schizophrenia	1.7	4.2	9.8	-1.9	-1.8	-3.1	-2.8	-1.4	-2.2	-2.7	-1.6	-1.3	-0.2	-2.1	-2.5	-2.7	-1.1	-1.7	-1.6
Age at first live birth	1.7	3.1	5.3	1.0	2.3	2.1	1.6	1.4	1.7	2.3	2.1	1.5	0.6	1.5	2.2	1.6	1.7	1.8	1.6
Medication: Blood pressure	1.7	2.9	6.9	-1.6	-1.2	-0.7	-0.8	-1.6	-1.4	-1.2	-1.6	-2.2	-2.6	-1.8	-2.1	-0.7	-2.1	-2.0	-2.3
Eye problems/disorders: Cataract	1.7	1.9	5.7	2.4	1.7	0.8	1.6	1.3	1.8	1.6	1.7	-0.1	0.1	-0.3	1.6	1.1	1.3	1.2	1.4
Depression (Nagel 2018)	1.6	2.4	4.9	-1.4	-1.4	-1.5	-1.5	-1.5	-1.2	-2.2	-1.0	-1.9	-1.3	-2.0	-1.4	-1.1	-1.2	-1.7	-1.9
Schizophrenia (2018)	1.6	3.4	6.0	-1.2	-1.2	-2.5	-2.1	-1.6	-2.1	-2.4	-1.8	-1.6	-0.4	-2.2	-1.9	-2.0	-1.5	-1.8	-1.8
Alzheimer’s Disease (in mother)	1.6	1.9	3.5	-1.1	-1.3	-1.6	-1.3	-1.3	-1.7	-1.7	-0.7	-1.4	0.3	-1.9	-1.4	-1.6	-0.7	-1.5	-1.5
Diabetes (mother)	1.6	2.0	3.9	0.6	1.5	2.0	1.6	1.7	1.8	1.5	1.3	1.5	1.3	1.1	1.8	1.4	1.5	0.9	0.3
Multivitamins +/- minerals	1.6	2.0	5.3	-1.1	-0.5	-1.4	-1.1	-1.4	-1.6	-1.4	-1.5	-1.5	-2.3	-1.7	-1.2	-1.1	-1.8	-1.3	-1.2
Alcohol intake versus 10 years previously	1.6	2.4	7.9	-0.9	-0.4	-0.5	-2.0	-1.0	-0.9	-1.4	-2.8	-0.6	0.7	-2.2	-0.8	-2.1	-1.1	-2.2	-2.0
Pulse rate, automated reading	1.6	5.1	8.9	-2.1	-2.3	-1.8	-2.2	-1.6	-1.7	-2.0	-2.9	-2.5	-1.9	-3.0	-2.3	-2.5	-2.3	-2.5	-2.0
Pain type(s) experienced in last month: Hip pain	1.6	2.0	6.6	1.0	1.8	0.5	1.6	1.6	2.6	1.4	0.6	1.1	2.1	0.3	1.7	1.3	1.2	1.0	0.7
Medication for hormone replacement therapy	1.5	1.7	3.5	0.3	1.7	1.4	1.9	1.0	1.5	1.3	1.4	0.8	0.7	1.7	1.0	1.8	0.7	1.3	0.9
Mineral and other dietary supplements	1.5	2.0	4.8	1.1	0.2	1.5	1.2	1.5	0.8	1.3	2.0	1.9	1.3	1.4	1.3	1.4	2.2	1.5	1.1
Age started oral contraceptive pill	1.5	1.8	3.7	0.1	1.1	1.4	1.5	1.9	1.6	1.9	1.1	1.1	1.1	1.9	1.0	1.4	1.0	1.2	1.2
Fasting Glucose	1.4	1.6	3.3	-0.4	-0.3	-1.8	-0.5	-1.2	-1.8	-1.4	-0.7	-1.7	-1.8	-1.2	-0.8	-0.3	-1.3	-1.5	-1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	3.6	-1.6	-0.1	-1.6	-0.6	-1.5	-1.1	-1.9	-1.0	-1.7	-1.8	-0.7	-1.1	-0.2	-1.7	-1.4	-1.8
Number of incorrect matches in round	1.4	2.4	7.5	0.7	0.9	1.3	1.2	2.2	1.2	1.0	1.0	2.7	2.2	1.7	1.1	1.2	1.6	1.6	1.5
Chest pain or discomfort	1.4	2.0	5.0	-2.2	-1.8	-0.2	-1.1	-1.4	-0.7	-1.8	-1.1	-0.8	-1.9	-0.5	-1.5	-0.6	-1.6	-1.4	-1.8
Leg fat-free mass (right)	1.4	7.7	14.3	3.3	1.5	2.7	2.7	2.9	2.9	2.9	2.8	3.3	3.0	1.8	3.2	1.9	3.8	2.5	2.2
Leg predicted mass (right)	1.4	7.6	14.1	3.2	1.4	2.7	2.6	2.9	2.9	2.8	2.8	3.3	2.9	1.8	3.1	1.9	3.8	2.5	2.2
Ever taken oral contraceptive pill	1.4	1.5	3.0	-0.7	-0.2	-1.3	-1.7	-1.5	-1.0	-1.3	-1.6	-1.1	-1.2	-1.2	-1.1	-1.7	-1.4	-0.9	-0.6
Medication: Bendroflumethiazide	1.4	2.1	5.0	-1.8	-2.2	-0.8	-0.7	-1.8	-2.0	-1.1	-1.0	-1.4	-1.4	0.3	-1.9	-0.2	-1.7	-1.3	-1.4
Loud music exposure frequency	1.3	1.4	5.6	-1.3	-1.0	-0.7	-2.1	-1.0	-0.7	-1.1	-1.4	-0.2	0.2	-1.1	-1.1	-2.4	-0.5	-0.9	-0.5
Emphysema/chronic bronchitis	1.3	1.5	3.4	0.7	1.6	-0.6	1.5	1.6	0.5	1.1	1.8	0.7	-0.7	0.7	1.0	1.7	1.2	1.4	1.4
Age at last live birth	1.3	1.9	4.0	1.4	1.8	2.0	0.9	1.1	1.5	1.9	1.5	1.1	-0.4	1.0	1.8	1.0	1.5	1.1	1.1
Medication: Aspirin	1.3	1.8	3.5	-1.9	-0.9	-1.9	-0.3	-1.6	-1.4	-1.4	-0.6	-1.8	-0.4	-1.3	-1.8	-0.4	-1.3	-1.2	-1.4
HbA1C	1.2	1.3	2.2	-1.0	-1.4	-1.1	-0.8	-1.3	-1.4	-1.1	-1.0	-1.5	-0.9	-1.4	-1.4	-0.6	-1.4	-0.7	-0.8
Severe depression (siblings)	1.2	1.3	4.3	0.0	-0.0	-0.2	-0.5	-1.1	-0.4	-0.8	-1.8	-1.7	-0.9	-0.6	-0.7	-0.7	-1.7	-1.9	-2.1
Age when periods started (menarche)	1.2	2.9	5.6	1.9	2.4	0.4	2.1	1.3	1.3	1.4	2.0	2.0	0.4	1.7	1.9	2.1	1.5	2.0	1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	5.3	-1.2	-1.6	-1.7	-2.2	-1.5	-1.6	-1.2	-1.7	-1.6	-1.8	-2.0	-1.2	-2.3	-1.2	-1.7	-1.1
Prospective memory result	1.2	1.4	4.7	-0.8	-0.6	-0.8	-1.2	-1.1	-1.1	-1.1	-1.5	-1.3	-0.6	-2.2	-1.5	-1.0	-1.3	-1.1	-1.0
Angina (self-reported)	1.2	1.5	3.9	-1.6	-0.4	-0.3	0.0	-0.9	-0.5	-0.8	-0.3	-1.7	-1.9	-1.8	-1.3	0.3	-1.4	-1.5	-2.0
Alcohol intake frequency.	1.2	2.7	4.8	-1.6	-1.4	-1.2	-1.6	-1.9	-1.0	-1.7	-2.2	-1.7	0.7	-1.0	-2.0	-1.9	-1.9	-2.0	-1.9
Commuting to job workplace: Car/motor vehicle	1.2	1.3	3.5	1.4	1.6	0.6	0.9	1.2	1.9	0.7	0.5	1.0	1.5	1.0	1.2	1.1	0.8	1.0	1.0
Ever depressed for a whole week	1.2	1.5	4.8	-0.3	-0.1	-2.1	-1.2	-0.8	-1.0	-1.1	-0.9	-1.5	-0.8	-2.2	-0.8	-1.7	-0.7	-1.4	-0.8
Townsend deprivation index at recruitment	1.1	1.6	3.6	-1.1	-1.9	-0.8	-0.6	-1.3	-1.7	-1.1	-1.1	-1.2	-1.6	-1.5	-1.1	-0.2	-1.5	-1.0	-1.2
Birth weight	1.1	2.4	4.9	1.3	1.0	1.3	2.2	2.0	0.8	2.0	1.2	1.9	0.7	1.6	1.7	1.9	1.3	1.4	1.0
Number of full brothers	1.1	1.4	4.4	-2.1	-1.1	-1.2	-0.5	-0.7	-1.5	-1.3	-1.2	-0.7	-1.2	-0.1	-1.2	-0.1	-1.4	-1.2	-1.4
Supplements: Vitamin C	1.1	1.3	3.5	-0.2	-1.0	-1.0	-1.4	-1.5	-0.8	-1.1	-1.9	-1.4	0.1	-0.3	-1.2	-1.6	-1.5	-1.1	-0.5
Illnesses of siblings: Diabetes	1.1	1.3	4.3	0.7	0.9	2.1	1.1	1.0	1.2	1.0	1.0	1.5	0.9	1.6	0.9	1.4	1.0	0.7	0.3
Trunk fat percentage	1.0	4.0	9.2	0.6	1.5	1.8	3.0	2.2	2.0	2.4	2.8	1.2	1.1	1.5	1.5	3.0	2.2	2.0	1.5
Worrier / anxious feelings	1.0	1.8	5.1	-1.8	-2.3	-1.0	-1.3	-1.3	-1.5	-1.1	-1.0	-1.3	-1.0	-1.0	-1.9	-1.5	-1.4	-0.8	-0.6
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	7.5	-1.3	-1.3	-0.3	-0.6	-0.7	-0.9	-1.1	-0.6	-0.6	-2.7	-0.4	-0.9	-0.3	-0.9	-1.1	-1.1
Medication for cholesterol	1.0	1.5	3.5	-0.6	-0.3	-0.8	-1.9	-1.3	-0.9	-1.6	-1.4	-0.9	0.0	-1.7	-0.4	-1.7	-0.7	-1.8	-1.7
Medication: Aspirin	1.0	1.3	3.1	-1.4	-0.6	-1.8	-0.0	-1.3	-1.2	-1.1	-0.3	-1.7	-0.3	-1.3	-1.5	-0.2	-1.1	-0.9	-1.2
Medication: Paracetamol	1.0	1.6	5.9	0.8	1.9	2.1	1.2	0.9	2.4	1.6	0.7	0.6	0.3	0.5	0.9	1.0	0.5	1.3	1.2
Bipolar Disorder (2018)	0.9	1.4	3.8	-1.5	-1.5	-1.9	-1.8	-0.3	-1.3	-1.3	-0.2	-0.0	0.2	-0.6	-1.6	-1.8	0.2	-0.5	-0.2
Reaction Time	0.9	1.7	5.1	-0.6	-0.4	-1.9	-1.4	-1.6	-2.3	-1.8	-1.3	-1.2	-0.7	-0.6	-1.5	-1.2	-1.6	-0.9	-0.6
Breast Cancer	0.9	2.1	3.0	-1.5	-1.0	-1.7	-1.1	-1.7	-1.5	-1.2	-1.5	-1.7	-1.2	-1.5	-1.4	-1.2	-1.5	-1.7	-1.5
Age at First Birth	0.9	1.3	3.3	-0.7	-1.1	0.0	-1.3	-1.1	-0.7	-0.7	-1.4	-1.4	0.2	-1.2	-1.0	-1.1	-1.1	-1.8	-1.8
Diabetes (father)	0.9	1.1	3.7	1.5	1.6	-0.1	0.6	1.4	1.2	0.8	0.8	0.7	1.9	0.4	1.3	0.3	1.5	0.3	0.4
Breastfed as a baby	0.9	1.1	5.5	0.3	1.1	0.9	1.8	0.8	1.1	1.1	1.1	-0.2	0.0	1.0	0.9	2.3	0.3	-0.1	-0.7
Eye problems/disorders: None of the above	0.9	1.0	4.6	-2.1	-1.0	-0.5	-0.6	-1.0	-1.1	-0.9	-1.1	-0.1	-0.1	0.6	-1.3	-0.3	-1.4	-0.6	-1.1
Whole body fat mass	0.9	3.6	8.0	1.2	1.3	1.8	2.8	2.0	1.9	2.3	2.6	1.3	1.0	1.3	1.6	2.7	2.1	1.8	1.4
Osteoporosis (self-reported)	0.9	1.1	2.9	0.8	1.1	1.1	1.1	0.1	1.1	1.3	1.4	0.7	1.7	0.2	0.8	1.4	0.9	1.1	0.9
Miserableness	0.9	1.5	4.2	-0.4	-0.8	-0.2	-1.2	-1.4	-1.0	-1.1	-1.2	-1.0	-2.0	-1.5	-0.9	-1.4	-1.4	-1.4	-1.3
Guilty feelings	0.9	1.4	2.7	-1.6	-0.9	-1.6	-0.6	-1.3	-0.5	-1.6	-0.7	-0.7	-1.6	-1.2	-1.5	-0.3	-1.4	-0.8	-1.0
High cholesterol (Self-reported)	0.9	1.6	5.0	-0.2	0.1	1.7	2.2	1.0	0.9	1.4	1.5	0.9	0.1	1.3	0.4	2.2	0.6	1.5	0.9
Illnesses of father: High blood pressure	0.9	1.1	3.6	0.3	1.0	1.5	0.4	0.9	1.0	0.4	0.7	1.8	1.9	0.8	1.0	0.4	1.6	0.9	0.5
Supplements: Glucosamine	0.8	1.0	4.8	-0.4	-0.7	-1.0	-1.1	-0.5	-0.9	-0.5	-1.1	-0.9	-2.2	-0.9	-1.0	-1.4	-1.1	-0.6	-0.2
Qualifications: None of the above	0.8	1.7	4.8	-2.1	0.2	-1.6	-0.1	-0.8	-0.9	-0.6	-1.4	-1.9	-2.0	-0.1	-1.4	-0.4	-2.2	-1.1	-1.0
Heart attack	0.8	1.0	2.3	-0.9	-0.1	-0.4	-0.3	-0.9	0.6	-0.8	-0.8	-1.4	-1.5	-1.3	-0.7	-0.3	-1.4	-1.2	-1.4
Pain all over the body in last month	0.8	0.8	3.9	0.8	0.3	2.0	0.9	0.5	0.8	1.0	0.8	0.8	0.9	0.9	1.0	1.1	0.8	0.3	0.1
Medication: Ramipril	0.8	1.0	2.6	-1.1	-1.1	0.0	0.1	-1.1	-0.8	-0.6	-1.0	-1.6	-0.5	-0.2	-1.1	0.4	-1.6	-1.2	-1.6
Noisy workplace	0.8	1.0	2.9	-1.7	-0.9	-1.2	-0.6	-0.9	-1.1	-1.5	-0.7	-0.9	0.0	-1.2	-0.7	-0.6	-0.6	-0.9	-1.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.3	1.6	1.0	0.6	-0.2	0.9	1.2	0.5	0.5	1.6	1.8	1.0	1.5	-0.4	1.3	1.1	1.4
Medication: Amlodipine	0.8	1.1	3.4	0.8	1.3	0.6	1.8	1.1	0.7	1.1	0.7	1.2	-0.7	1.0	0.7	1.6	0.4	1.0	0.5
Medication for pain relief, constipation, heartburn	0.8	1.4	3.3	1.6	0.4	0.4	0.2	1.4	0.1	1.0	1.1	1.8	0.7	1.3	1.3	0.2	1.6	1.5	1.7
Ever had bowel cancer screening	0.8	0.9	3.1	0.4	0.2	0.0	0.3	0.9	0.3	0.9	1.3	1.6	0.2	1.4	0.4	0.7	1.0	1.5	1.8
Fractured/broken bones in last 5 years	0.8	1.0	2.5	-1.2	-1.6	-1.4	-1.0	-0.6	-1.4	-1.5	-0.2	0.1	0.8	0.5	-1.4	-1.0	-0.3	-0.2	-0.2
Supplements: Calcium	0.8	0.8	2.1	-1.2	-0.7	-0.7	-0.8	-1.2	-1.1	-0.7	-0.7	-1.2	-0.7	-0.2	-1.4	-0.7	-1.4	-0.6	-0.3
Average weekly spirits intake	0.7	0.9	3.7	1.9	1.6	1.1	0.7	0.8	0.7	1.0	0.9	0.3	-0.1	0.3	1.2	0.6	0.9	-0.0	-0.0
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.3	-0.6	1.5	0.3	1.6	0.2	1.1	0.6	1.1	-0.1	0.4	1.6	-0.2	1.8	-0.2	0.6	0.1
Fed-up feelings	0.7	1.3	8.7	-1.2	-0.6	0.0	-0.1	-1.0	-0.5	-0.8	-0.7	-1.1	-3.0	-1.7	-0.9	0.0	-1.4	-0.6	-0.7
Qualifications: CSEs or equivalent	0.7	0.9	3.8	2.0	0.9	1.0	0.8	0.8	0.8	1.2	0.4	0.6	-0.2	-0.6	1.2	0.5	0.8	0.9	1.0
Hair/balding pattern: Pattern 2	0.7	0.9	2.8	0.9	1.2	1.7	1.0	0.7	1.2	1.1	0.9	0.7	-0.1	1.2	1.0	1.0	0.6	0.7	0.5
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	4.6	0.2	-0.3	-1.8	-1.0	-0.7	-0.7	-0.9	-0.2	-1.0	-0.1	-2.1	-0.7	-1.3	-0.2	-0.5	-0.2
Father’s age at death	0.7	0.9	2.7	0.4	0.4	0.4	1.5	1.0	0.5	1.3	1.6	0.2	0.6	1.5	0.7	1.2	0.9	0.8	0.6
Exposure to tobacco smoke at home	0.7	0.8	4.5	0.4	0.4	-0.2	1.4	-0.5	-0.1	0.3	2.1	0.2	0.0	0.2	0.3	1.7	0.6	1.2	0.6
Tense / ‘highly strung’	0.7	1.1	5.1	-0.4	-0.1	-1.8	-0.3	-0.9	-0.9	-0.7	-0.7	-1.4	-2.2	-0.8	-1.2	-0.6	-1.6	-0.5	-0.4
Average weekly champagne plus white wine intake	0.7	1.0	2.6	1.6	0.8	-0.5	1.0	0.9	-0.5	0.9	1.5	0.2	-0.5	0.4	1.0	1.0	1.1	1.2	1.6
Unable to work because of sickness or disability	0.7	0.9	2.1	-1.2	-1.1	-1.0	-0.1	-1.5	-0.7	-1.3	-0.6	-1.2	-0.3	-0.3	-0.9	0.4	-1.4	-0.6	-0.8
Depressed Affect (Nagel 2018)	0.6	1.3	3.8	-0.6	-0.6	-0.6	-0.8	-1.1	-0.8	-1.0	-1.0	-1.4	-1.4	-1.9	-1.0	-0.7	-1.2	-1.4	-1.5
Bipolar Disorder (2011)	0.6	0.6	2.7	-1.2	-1.3	-1.2	-1.6	-0.3	-1.1	-1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.6	0.7	1.5	0.6	0.8	-0.8	1.1	1.2	0.1	0.6	1.2	0.6	0.3	0.7	0.6	0.9	0.8	1.0	1.1
Relative age of first facial hair	0.6	1.1	3.6	-1.4	-0.0	-0.5	-1.0	-1.3	-0.3	-1.9	-1.3	-0.2	0.0	-0.1	-0.9	-0.7	-1.1	-1.3	-1.9
Medication: Co-codamol	0.6	0.7	3.0	-1.0	0.2	0.2	-0.4	-0.3	-0.1	-0.3	-1.7	-0.7	-0.6	-0.6	-0.3	-0.5	-1.3	-1.4	-1.5
Relative age voice broke	0.6	0.9	2.0	-1.1	-0.8	-0.6	-1.1	-1.3	-0.6	-1.4	-1.3	-0.5	0.9	-0.4	-0.8	-0.9	-0.8	-1.0	-1.2
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.0	-0.1	1.0	0.6	1.3	0.2	1.1	0.8	0.2	0.5	0.7	0.9	0.6	1.7	-0.5	0.7	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	2.9	-0.6	-0.5	-1.0	-0.5	-1.1	-0.5	-1.7	-1.1	-0.7	-1.3	-1.3	-0.8	-0.3	-1.3	-0.8	-1.2
Financial difficulties in last 2 years	0.6	0.8	2.1	-0.0	-0.7	-1.2	-0.2	-1.4	-0.5	-1.2	-0.3	-1.2	0.2	-1.4	-1.2	0.5	-0.9	-0.3	-0.4
Allergy	0.6	1.4	3.5	-0.6	0.1	-1.0	-0.7	-1.6	-1.4	-1.4	-1.6	-1.3	-0.7	-1.5	-1.0	-0.5	-1.9	-1.1	-1.1
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	2.5	-1.3	-1.0	-1.1	0.1	-0.8	-1.6	-1.0	0.5	-1.3	-0.4	-0.8	-1.1	0.5	-0.5	-0.3	-0.6
Pulse wave reflection index	0.6	0.7	3.4	0.4	0.2	0.2	-0.1	-0.5	-0.9	0.0	-1.4	-1.1	-1.9	-0.6	-0.4	-0.2	-1.5	-0.5	-0.2
Wears glasses or contact lenses	0.6	0.7	3.0	-0.5	-0.5	-0.6	-0.0	-0.4	-0.6	-0.4	-0.5	-1.7	-1.5	-0.3	-0.8	0.2	-1.1	-1.1	-1.2
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.1	-0.4	-1.0	-1.3	-0.5	-0.7	-1.0	0.1	-0.3	-1.0	-1.2	-0.6	-1.4	-0.3	-1.0	0.4	1.0
Eye problems/disorders: Glaucoma	0.6	0.7	2.0	-0.0	-1.4	-0.1	-0.6	-0.9	-0.7	-1.2	-0.2	-1.0	0.1	-1.0	-0.6	0.0	-0.2	-1.1	-1.3
Ever smoked	0.6	1.1	4.2	0.1	1.1	0.0	1.7	1.0	0.6	0.6	2.1	0.6	-0.1	0.4	1.1	2.0	1.2	0.6	-0.2
Irritability	0.6	1.0	4.9	-0.1	-0.3	-0.8	-0.4	-0.8	-0.9	-0.6	-0.7	-1.4	-2.2	-1.6	-1.0	-0.8	-1.2	-0.7	-0.8
Pack years of smoking	0.6	0.9	2.0	-1.0	-0.9	-1.3	-0.5	-0.9	-0.6	-1.3	-0.3	-1.2	-0.5	-0.9	-0.9	-0.5	-0.5	-1.3	-1.4
Coronary Artery Disease (CAD)	0.5	0.5	1.3	-1.1	-0.9	-1.1	-0.8	-0.7	-0.6	-0.8	-0.5	-0.8	0.1	-0.1	-0.8	-0.8	-0.5	-0.6	-0.4
Cardiovascular Disease	0.5	1.5	5.7	-0.6	0.9	0.8	2.3	0.7	0.6	0.9	1.9	0.8	0.1	2.0	0.1	2.4	0.5	1.2	0.5
Number of treatments/medications taken	0.5	0.9	4.2	-0.9	-0.1	-0.6	0.4	-1.4	-0.1	-0.3	-0.4	-2.0	-1.3	-0.6	-1.2	0.6	-1.4	-0.6	-0.7
Ever had hysterectomy (womb removed)	0.5	0.5	1.7	-0.6	-0.3	-0.6	-1.3	-0.4	-0.2	-0.7	-0.9	-0.6	0.5	-0.6	-0.8	-1.2	-0.6	-0.7	-0.4
Pack years adult smoking proportion	0.5	0.8	1.7	-0.8	-0.8	-1.2	-0.6	-0.9	-0.5	-1.3	-0.4	-1.0	-0.8	-1.0	-0.8	-0.6	-0.5	-1.1	-1.2
Stomach or abdominal pain in last month	0.5	0.6	1.3	-0.8	-0.6	-0.6	-0.9	-0.7	-0.7	-1.0	-0.9	-0.2	0.1	-1.1	-0.4	-0.7	-0.3	-1.0	-1.2
High blood pressure (mother)	0.5	0.7	2.9	-0.0	-0.8	0.7	-1.5	-0.1	-0.0	-0.1	-0.7	1.2	1.7	0.3	-0.1	-1.7	0.6	-0.1	0.3
Past tobacco smoking	0.5	0.9	2.8	-0.2	-1.2	-0.0	-1.4	-1.0	-0.3	-0.4	-1.7	-1.0	-0.3	-0.5	-1.2	-1.5	-1.2	-0.7	0.0
Neuroticism score	0.5	1.0	2.5	-1.1	-0.7	-0.8	-0.5	-1.0	-0.8	-1.1	-0.5	-1.0	-1.6	-1.5	-1.1	-0.5	-1.2	-0.7	-1.0
Falls in the last year	0.5	0.7	2.1	0.0	-0.9	-0.2	-0.7	-0.6	-0.1	-1.1	-0.6	-1.0	0.3	-1.4	-0.6	-0.4	-0.1	-1.3	-1.5
Qualifications: A levels/AS levels or equivalent	0.5	1.1	5.6	1.0	-0.4	0.3	-0.1	0.6	0.6	0.6	1.2	1.1	2.4	0.5	0.6	-0.3	1.5	1.3	1.5
Depression (self-reported)	0.5	0.5	1.8	-0.3	1.3	1.3	1.0	0.7	0.6	0.6	0.2	0.1	-0.1	0.3	0.7	1.3	0.2	-0.3	-0.8
Comparative body size at age 10	0.5	1.3	5.0	-0.9	-2.2	-0.8	-1.4	-0.8	-1.2	-1.6	-0.6	-0.6	0.0	-0.7	-1.4	-1.3	-0.5	-0.9	-1.0
Worry too long after embarrassment	0.5	0.9	3.0	-1.7	-1.7	-0.7	-0.9	-0.7	-1.0	-1.1	-0.6	0.3	-0.2	-0.5	-0.9	-0.7	-0.5	-0.8	-1.0
Migraine (self-reported)	0.5	0.6	2.2	1.1	-0.3	-0.4	0.5	0.8	-0.5	0.3	0.9	0.7	0.8	-0.2	0.5	0.4	1.2	1.3	1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	3.4	0.4	0.5	1.8	0.6	0.0	1.5	0.3	0.4	-0.7	-0.3	0.1	0.2	0.8	-0.2	-0.4	-0.9
Osteoarthritis (self-reported)	0.5	0.6	2.6	0.8	0.6	0.0	0.1	0.9	0.1	0.7	0.6	1.2	1.6	0.9	0.4	-0.2	0.6	1.0	1.2
Medication: Blood pressure	0.5	0.9	2.7	0.1	-0.1	-0.2	1.3	0.8	0.5	1.0	0.9	0.8	0.7	1.7	0.2	1.3	0.5	1.3	1.4
Medication: Atorvastatin	0.5	0.7	2.2	-1.5	-0.7	-0.0	1.1	-0.3	-1.1	-0.3	0.9	-0.4	-1.2	-0.4	-0.7	1.4	-0.4	0.2	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.7	0.6	0.1	0.2	1.2	0.3	0.8	1.0	1.3	-0.1	0.1	0.4	0.4	1.0	0.4	1.2	1.0
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.8	-0.9	0.1	-0.2	-0.1	-0.7	0.7	-0.7	-0.6	-1.1	-1.2	-1.1	-0.5	-0.1	-1.1	-1.1	-1.3
Crohns Disease (2017)	0.4	0.9	5.7	-0.3	-2.4	-0.3	-1.1	-0.7	-1.0	-0.8	-0.6	-0.6	0.2	-1.2	-1.0	-1.4	-0.4	-0.6	-0.3
Irritable Bowel Disease (IBD)	0.4	0.9	2.1	1.2	0.2	0.7	0.5	0.8	1.3	0.9	1.0	0.9	1.4	1.0	0.4	0.1	0.9	1.2	1.4
Type 2 Diabetes (T2D) (2012)	0.4	0.4	2.8	0.8	0.7	-0.1	0.1	0.2	0.6	0.4	0.1	0.7	1.7	-0.4	1.0	0.2	0.8	0.1	-0.1
Medication: Atenolol	0.4	0.5	1.7	-0.5	-0.8	0.7	0.4	-0.8	-0.4	-0.3	-0.5	-0.3	-1.3	-0.3	-0.8	0.6	-1.0	-0.3	-0.9
Had other major operations	0.4	0.5	1.3	-0.6	-0.5	-0.0	-0.1	-1.0	-0.6	-0.5	-1.1	-1.1	0.6	-0.6	-0.7	0.0	-1.2	-0.8	-0.9
Fluid intelligence score	0.4	0.7	3.0	0.6	-0.4	-0.3	-0.9	0.6	0.3	0.1	0.9	1.7	0.4	0.1	0.5	-1.0	1.6	0.8	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.8	-0.6	-1.1	-0.7	0.6	-1.4	-1.0	-1.2	0.3	-1.1	-0.4	-0.8	-0.7	0.9	-0.7	-0.1	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.2	0.0	-0.2	1.1	-0.8	0.1	0.9	0.2	-1.1	0.8	-1.0	0.4	0.2	-0.9	-0.3	-0.2	0.1
Medication: Lansoprazole	0.4	0.4	1.2	-0.1	-0.0	0.3	-0.4	-0.7	0.6	0.1	-0.8	-1.1	-0.0	-0.8	-1.1	-0.1	-1.0	-0.5	-0.4
Pulse wave Arterial Stiffness index	0.4	0.5	1.5	0.2	1.2	0.1	0.8	1.0	0.8	0.7	0.7	0.3	-0.4	0.3	0.9	0.8	0.8	0.6	0.7
Birth weight of first child	0.4	0.7	2.7	-0.0	0.4	1.6	1.0	0.8	1.5	0.3	0.4	0.4	1.6	-0.3	0.7	0.8	0.8	-0.2	-0.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.7	1.9	-0.5	0.2	-0.0	0.3	0.1	0.0	0.4	0.8	1.8	-0.4	0.6	0.0	1.0	0.7	0.7
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	3.0	0.8	-0.3	-1.1	-0.3	0.4	-0.2	-0.1	0.4	0.8	0.6	-0.7	-0.1	-0.6	0.8	1.2	1.7
Medication: Paracetamol	0.4	0.7	3.6	0.1	1.4	1.6	0.7	0.3	1.9	0.7	-0.0	0.0	0.8	-0.1	0.5	0.7	-0.0	0.4	0.2
Headache pain in last month	0.4	0.6	2.1	0.1	-0.1	-1.1	-0.5	-0.9	-0.4	-0.9	-1.0	-1.1	-0.7	-1.4	-0.9	-0.4	-0.9	-0.2	0.0
Gout (self-reported)	0.4	0.6	1.7	0.8	-0.6	-0.5	-0.6	0.3	-0.5	0.1	0.8	0.6	1.2	0.3	0.1	-1.3	1.2	0.6	1.1
Neck or shoulder pain in last month	0.4	0.5	1.6	-0.4	-0.5	-1.3	-0.8	-1.1	-0.6	-1.1	-0.2	-0.8	0.1	-0.9	-0.5	-0.5	-0.3	-0.5	-0.4
Medication: Omeprazole	0.4	0.4	1.8	1.4	0.2	-0.2	0.6	0.0	0.5	0.8	0.6	-0.5	-0.1	-0.1	0.2	0.3	0.0	1.1	1.3
Number of full sisters	0.4	0.5	1.8	-0.6	-0.5	0.9	-0.4	-0.8	0.1	-0.7	-1.1	-0.1	-0.5	-0.1	-0.1	-0.1	-0.5	-1.2	-1.4
Overall health rating	0.4	0.9	2.2	-1.1	-0.8	-1.4	-0.1	-1.0	-0.8	-1.2	0.0	-1.2	-0.0	-1.5	-1.0	0.1	-0.6	-0.8	-1.1
Smoking status: Current	0.4	0.7	1.9	1.2	0.5	1.0	0.4	1.1	1.4	0.4	0.4	1.0	0.0	-0.5	1.2	0.7	1.3	-0.1	-0.3
Medication: Lisinopril	0.4	0.5	1.7	-0.0	0.3	0.2	0.4	0.5	0.2	0.7	1.3	0.5	0.7	0.7	0.3	0.5	1.0	0.8	1.1
Alcohol drinker status: Previous	0.4	0.4	2.5	0.2	0.2	0.1	1.1	-0.0	-0.1	0.3	0.3	0.5	0.3	1.6	0.3	1.4	-0.3	0.5	0.2
Schizophrenia vs Biploar Disorder	0.3	0.4	3.0	0.2	1.0	0.8	0.7	0.4	0.5	0.6	-0.5	0.0	0.4	1.7	0.5	0.5	-0.6	-0.1	-0.3
Primary Biliary Cirrhosis	0.3	0.4	1.1	0.3	-0.2	-0.2	-0.8	-0.7	0.3	0.0	-0.5	-1.0	-1.0	-0.5	-0.7	-0.9	-0.7	-0.3	0.1
Hearing difficulty/problems: Yes	0.3	0.5	1.7	-0.6	-0.4	-0.6	0.6	1.0	1.0	-0.2	0.4	1.0	1.3	1.0	0.3	0.7	0.5	0.5	0.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.2	-0.1	-1.1	-0.5	-0.5	-0.2	-0.5	-0.5	-0.6	-0.7	0.0	-0.8	-0.4	-0.6	-0.4	-0.6	-0.5
Supplements: Zinc	0.3	0.3	1.3	0.8	0.2	-0.1	0.7	-0.6	-0.3	0.2	0.7	-0.4	-1.1	1.0	0.3	0.5	-0.3	0.5	0.5
Current tobacco smoking	0.3	0.5	1.6	0.9	0.4	0.9	0.6	0.7	1.3	0.3	0.2	0.5	-0.2	-0.5	0.9	0.8	0.8	-0.2	-0.5
High blood pressure	0.3	0.8	2.2	-1.4	-1.4	-0.7	0.7	-1.0	-0.9	-0.6	0.3	-0.5	-0.9	0.3	-1.5	1.2	-0.9	0.1	-0.4
Chronic bronchitis/emphysema (father)	0.3	0.4	1.3	0.2	0.2	1.1	0.6	0.4	0.5	0.7	1.1	0.4	1.1	-0.1	0.3	0.4	0.9	0.6	0.2
Medication: Simvastatin	0.3	0.4	2.0	0.6	0.3	1.1	0.8	0.7	1.4	1.0	0.2	0.0	-0.6	0.1	0.1	0.4	0.1	0.3	0.3
Number of live births	0.3	0.4	1.3	-0.1	-0.2	-0.7	-0.7	-0.9	-0.3	-0.6	-0.3	-0.8	-1.1	-1.0	-0.4	-0.5	-0.5	-0.7	-0.5
Happiness	0.3	0.4	2.1	-0.5	-0.6	0.3	-1.1	-0.2	0.0	-0.6	-0.7	0.2	-0.6	-1.4	-0.3	-1.0	0.1	-0.4	0.0
Asthma	0.3	0.6	2.6	0.5	-0.3	1.0	-0.2	1.4	0.8	0.7	0.7	1.2	-0.0	0.4	0.6	-0.5	1.6	0.4	0.7
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.5	-0.6	0.2	-1.1	0.7	0.3	-1.0	-0.0	0.5	-1.0	-1.2	-0.8	-0.5	0.9	-0.4	0.3	0.2
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.0	-0.7	-0.7	-1.0	-0.7	0.4	-0.6	-0.1	-0.3	-0.2	-1.0	0.2	-0.6	-0.7	-0.1	0.0	0.5
High blood pressure (siblings)	0.3	0.4	1.7	-0.4	-0.3	0.8	0.5	-0.8	-0.0	-0.3	-0.1	-0.4	1.3	-0.2	-0.0	0.9	-0.3	-0.6	-1.1
Body fat percentage	0.3	1.1	4.5	-0.2	0.5	0.8	1.9	0.9	0.8	1.3	1.8	-0.2	-0.0	0.5	0.2	2.1	0.9	0.9	0.5
Wheeze or whistling in the chest in last year	0.3	0.5	2.6	-1.6	-0.7	-0.3	-0.5	0.1	0.4	-0.5	0.1	-0.4	1.2	-0.2	-0.4	-0.3	0.4	-0.9	-0.9
Number of children fathered	0.3	0.4	1.3	0.6	0.8	0.4	-0.0	0.8	0.9	0.5	-0.1	-0.3	-0.9	-1.1	0.9	-0.3	0.5	-0.4	-0.1
Qualifications: College or University degree	0.3	0.9	8.5	0.6	0.2	-0.4	-0.0	0.5	-0.3	-0.4	1.1	1.0	2.9	0.2	0.6	0.1	1.5	0.6	0.4
Family relationship satisfaction	0.3	0.3	1.1	0.3	-0.4	0.4	-1.0	0.0	-0.3	-0.8	-0.7	0.5	0.1	-1.0	-0.4	-0.7	-0.1	-0.6	-0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.7	-0.0	-0.5	-0.1	0.5	-0.4	-1.3	0.5	-0.0	-0.8	-1.2	0.5	-0.4	0.5	-1.0	0.1	0.2
Knee pain experienced in last month	0.3	0.4	2.0	0.9	0.1	-0.6	-0.5	-0.0	0.1	-0.4	-1.4	0.0	0.9	0.1	-0.0	-0.9	-0.6	-0.7	-0.3
Illnesses of father: Heart disease	0.3	0.5	2.1	-0.5	-0.5	-0.6	-0.4	-0.7	-0.2	-0.6	-0.9	-0.4	0.6	-0.1	-0.2	-0.6	-0.5	-1.3	-1.4
Smoking status: Previous	0.3	0.5	1.4	-0.2	0.9	-0.1	1.2	0.7	-0.0	0.4	1.0	0.5	0.2	0.7	0.8	1.1	0.5	0.7	0.3
Arm fat percentage (left)	0.3	1.1	3.6	-1.6	-1.4	-0.9	0.2	-0.9	-1.1	-0.5	0.2	-1.9	-0.9	-1.2	-1.7	0.3	-0.7	-0.6	-0.7
Long-standing illness, disability or infirmity	0.3	0.4	1.4	0.3	0.1	0.5	1.0	0.6	0.4	0.6	1.1	0.2	1.2	0.7	0.2	0.7	0.7	0.8	0.4
Friendships satisfaction	0.3	0.3	3.1	-0.0	-0.0	-0.1	0.4	0.2	0.3	0.2	0.7	-0.8	-1.8	-0.7	0.1	0.5	-0.1	0.0	0.0
Breast cancer (self-reported)	0.3	0.3	1.2	0.5	0.1	-0.0	0.2	0.2	0.1	0.3	0.9	0.7	0.5	0.7	0.2	0.3	0.6	0.9	1.1
Asthma (self-reported)	0.3	0.6	2.3	0.4	-0.2	1.1	-0.2	1.3	0.8	0.6	0.7	1.2	-0.1	0.4	0.6	-0.4	1.5	0.3	0.5
Illnesses of father: None of the above (group 1)	0.3	0.3	2.1	0.7	-0.2	0.1	0.1	-0.2	-0.2	0.3	-0.6	-0.3	-1.4	-0.0	-0.4	0.2	-1.1	0.4	0.7
Hearing aid user	0.3	0.4	2.0	-0.7	0.2	-0.8	0.6	0.2	0.5	0.1	0.7	-0.2	1.4	-0.2	-0.3	1.1	0.3	0.1	-0.1
Leg fat percentage (left)	0.3	1.0	3.7	-1.4	-0.6	-0.6	0.5	-0.6	-0.8	-0.2	0.4	-1.8	-1.9	-0.8	-1.2	0.7	-0.8	-0.6	-0.8
Myopia	0.3	0.5	2.8	0.1	-0.2	0.3	-1.4	-0.2	-0.0	-0.4	-1.3	0.4	-0.7	-0.4	0.0	-1.7	-0.1	-0.6	-0.2
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.3	1.1	0.9	0.3	-1.1	0.8	0.6	0.3	-0.5	0.9	1.4	-0.3	1.3	-1.5	1.1	-0.1	0.4
Pain experienced in last month	0.3	0.5	1.9	-0.0	-0.2	0.8	0.6	0.8	-0.0	0.9	1.1	0.7	0.4	1.4	0.2	0.3	0.8	0.9	0.8
Crohns Disease (2012)	0.2	0.3	1.4	-0.3	-1.2	-0.1	-0.5	-0.3	-0.2	-0.0	0.0	0.3	0.9	-0.7	-0.2	-0.9	0.4	0.1	0.3
Triglycerides	0.2	0.3	1.5	-0.6	-0.8	0.3	0.2	-0.2	0.1	-0.6	0.2	0.0	1.1	-0.2	0.1	0.5	0.3	-0.6	-1.2
Blood Platelet Count	0.2	2.3	6.4	0.7	1.7	0.6	2.2	1.4	1.0	1.5	2.5	0.9	-1.6	1.0	1.1	2.2	1.2	1.8	1.4
Smoking Status	0.2	0.5	1.0	0.2	1.0	0.5	0.5	0.9	0.9	-0.1	0.5	0.9	-0.3	-0.5	0.9	0.8	0.9	-0.3	-1.0
Allergy or Eczema	0.2	0.4	1.0	-0.2	-0.9	-0.8	-0.2	0.5	-0.3	0.1	0.9	0.6	1.0	0.9	-0.0	-0.5	1.0	0.5	0.8
Hypothyroidism (self reported)	0.2	0.4	1.1	-0.4	0.2	-0.7	0.5	0.1	-0.8	0.0	0.4	-1.1	-1.0	-0.5	-0.9	0.7	-0.6	0.4	0.5
Respiratory disease	0.2	0.5	1.9	0.3	-0.3	0.7	-0.2	1.2	0.7	0.9	0.7	0.7	-0.1	0.5	0.6	-0.4	1.4	0.2	0.6
Neuroticism	0.2	0.4	1.5	-0.1	0.1	-0.2	-0.1	-0.7	-0.2	-0.4	-0.2	-1.0	-1.2	-1.0	-0.5	-0.2	-0.9	-0.7	-0.9
Chronotype (morning person)	0.2	0.4	2.0	0.4	0.4	1.4	0.5	0.9	0.6	1.0	-0.6	0.2	-0.8	0.1	0.4	0.5	-0.3	-0.0	0.2
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	-0.6	0.0	0.3	0.3	-0.9	-0.2	-0.5	0.6	-0.1	1.1	0.7	-0.5	0.6	-0.2	0.0	-0.6
Medication: Metformin	0.2	0.3	1.2	-1.1	-0.3	-0.4	-0.7	-0.3	-0.2	-0.5	-0.0	-0.2	0.0	-0.6	-0.9	-0.9	0.1	-0.4	-0.4
Maternal smoking around birth	0.2	0.3	1.7	-0.6	-0.2	-1.3	0.4	0.1	-0.4	-0.2	0.9	0.4	-0.4	0.3	-0.3	0.0	0.6	0.8	0.9
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	0.2	-0.3	-0.7	-0.3	-0.4	-0.5	-0.1	0.5	-0.2	-0.6	0.5	-0.5	-0.3	0.1	0.4	0.6
Medication: Levothyroxine sodium	0.2	0.4	2.2	0.3	-0.0	-0.3	0.9	0.6	-0.4	0.4	0.4	-0.3	-1.5	-0.4	-0.1	1.0	-0.4	0.7	0.7
Nervous feelings	0.2	0.3	1.6	-0.6	-1.3	0.1	0.3	-0.4	-0.7	-0.3	0.3	0.4	-0.6	0.4	-0.6	0.5	-0.4	0.5	0.0
Hearing difficulty/problems with background noise	0.2	0.4	1.1	0.4	-0.1	0.5	1.0	0.7	1.1	0.6	0.3	0.7	0.1	0.9	0.4	0.9	-0.0	0.5	0.3
Had menopause	0.2	0.3	1.6	0.1	0.2	0.1	1.0	-0.0	0.3	0.2	0.8	-0.4	0.4	1.2	-0.1	1.0	-0.1	0.4	0.2
Mouth/teeth dental problems	0.2	0.4	1.9	0.8	0.1	0.5	0.3	0.4	0.1	1.1	0.7	-0.3	0.7	1.4	0.3	0.4	0.6	0.1	0.4
Arm fat percentage (right)	0.2	1.0	2.8	-1.5	-1.3	-0.8	0.2	-0.8	-1.0	-0.5	0.2	-1.7	-0.7	-1.2	-1.6	0.4	-0.5	-0.6	-0.7
Time employed in main current job	0.2	0.3	1.0	0.1	-0.5	-0.0	-0.5	-0.4	-0.2	-0.7	-0.9	-0.4	-0.5	-1.0	-0.5	-0.2	-0.5	-0.4	-0.3
Pulse rate	0.2	0.3	1.6	-1.1	-1.3	0.4	0.1	-0.3	0.5	-0.6	-0.5	-0.0	-0.4	-0.0	-0.6	0.1	-0.5	-0.5	-0.8
Mouth/teeth dental problems: Dentures	0.2	0.4	1.2	-0.4	0.1	0.5	0.6	-0.7	0.0	-0.7	-0.5	-0.4	-0.6	-0.6	-0.3	0.9	-1.1	-0.4	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.7	-0.4	0.1	-0.9	-0.4	-0.2	0.0	-0.6	-0.3	-0.7	-0.5	-0.7	-0.3	-0.4	-0.1	-0.5	-0.2
Lung cancer (father)	0.2	0.3	0.9	-0.1	-0.9	-0.7	0.4	-0.4	-0.4	-0.3	0.8	0.4	0.8	-0.2	-0.4	0.5	0.2	0.4	0.3
Illnesses of mother	0.2	0.2	1.0	-0.1	0.0	-0.0	0.8	-0.1	0.6	0.1	0.5	-0.2	-0.3	0.6	0.1	1.0	-0.3	0.6	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.1	-0.5	0.5	-0.8	-0.3	-0.6	-0.7	-1.0	-0.4	-0.3	-0.2	-0.8	-0.4	-0.5	-0.4	-0.6	-0.8
Hair/balding pattern: Pattern 4	0.2	0.4	1.6	0.9	1.2	0.3	-0.2	-0.2	0.5	0.7	-1.0	-0.5	-0.1	-0.4	0.1	-0.5	-0.7	-0.6	-0.4
Glaucoma (self-reported)	0.2	0.3	0.9	-0.4	-0.8	0.1	0.0	-0.5	-0.4	-0.8	0.1	-0.6	0.6	-0.5	-0.4	0.5	-0.1	-0.6	-0.9
Leg fat percentage (right)	0.2	0.9	3.8	-1.2	-0.5	-0.3	1.0	-0.5	-0.5	0.0	0.7	-1.6	-2.0	-0.3	-1.1	1.4	-0.7	-0.1	-0.4
Exposure to tobacco smoke outside home	0.2	0.3	1.1	0.2	0.5	0.1	1.0	-0.0	0.2	0.5	0.4	0.3	-0.3	-0.5	0.1	1.0	-0.1	0.8	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.3	-0.5	0.1	0.8	0.8	-0.2	-0.2	0.4	1.0	-0.7	-0.5	-0.1	0.1	1.2	-0.2	-0.0	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.4	1.2	0.6	-0.2	0.6	0.2	-0.3	0.3	0.5	0.1	-0.2	0.1	0.4	0.6	0.1	0.7	0.6
Pulse wave peak to peak time	0.2	0.3	1.7	0.6	-0.4	0.8	0.1	-0.1	0.3	0.2	0.2	0.9	1.3	0.6	0.2	0.0	0.3	0.3	0.1
Health satisfaction	0.2	0.3	1.4	-0.1	0.3	0.2	0.2	0.2	0.5	0.3	1.1	-0.5	-0.4	-1.2	-0.0	0.2	0.7	0.5	0.6
Shortness of breath walking on level ground	0.2	0.2	1.4	-0.4	-0.1	-0.5	0.7	0.3	-0.0	0.0	1.2	-0.2	0.7	0.2	-0.3	0.6	0.3	0.6	0.2
Mean time to correctly identify matches	0.2	0.5	2.5	0.0	0.1	-1.2	-0.3	-0.7	-1.6	-0.8	-0.3	-0.6	-0.4	0.5	-0.7	-0.2	-1.0	-0.3	-0.0
Leg fat mass (right)	0.2	0.9	3.6	0.2	0.3	0.8	1.9	0.8	0.6	1.2	1.7	-0.2	-0.5	0.3	0.3	1.9	0.9	0.8	0.4
Hypertension (Self-reported)	0.2	0.6	1.9	-1.1	-1.0	-0.2	1.0	-0.4	-0.5	-0.2	0.5	-0.3	-0.9	0.8	-1.0	1.4	-0.6	0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.0	-0.6	-1.0	-0.2	-0.2	0.0	-0.4	0.4	0.5	-0.4	-0.6	-0.3	-0.3	-0.5	0.0	0.4	0.6
Handedness (chirality/laterality): Left-handed	0.2	0.3	2.4	0.2	0.1	0.0	0.1	0.4	0.7	-0.1	-0.5	-0.3	-0.3	-1.6	0.4	-0.1	0.2	-0.5	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.8	0.6	0.9	0.4	0.2	0.4	0.8	0.3	0.1	0.5	0.1	-0.1	0.6	0.2	0.4	0.4	0.3
Commuting to job workplace: Walk	0.2	0.2	0.6	-0.5	-0.4	0.3	-0.5	0.0	-0.3	-0.1	-0.0	0.4	-0.6	0.8	-0.3	-0.7	0.1	-0.5	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.7	-0.9	0.4	0.5	-0.0	0.6	0.3	0.1	-0.5	1.3	-0.3	0.8	0.1	-0.2	-0.1	0.4	0.5
Back pain experienced in last month	0.2	0.3	1.1	-0.5	0.2	-0.5	0.6	-0.3	0.6	-0.6	-0.5	-0.4	-0.3	-0.8	-0.2	1.0	-0.9	-0.3	-0.7
Medication: Gliclazide	0.2	0.3	1.2	-0.3	-0.5	-1.0	-0.6	0.1	-1.1	-0.3	0.4	0.0	-0.0	-0.3	-0.6	-0.6	0.6	-0.3	-0.0
Number of self-reported non-cancer illnesses	0.2	0.3	1.2	-1.1	-0.4	0.5	0.7	-0.3	-0.2	0.1	0.9	0.1	0.0	0.4	-0.4	0.9	0.1	0.3	-0.0
Commuting to job workplace: Public transport	0.2	0.2	1.4	-0.6	-1.2	0.2	-0.1	-0.1	-0.5	-0.4	0.4	0.3	0.0	-0.5	-0.1	0.1	0.5	-0.1	-0.2
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.3	-0.5	0.5	-0.4	-0.5	-0.4	0.1	-0.3	-1.1	-0.3	0.0	-0.3	-0.2	-0.8	-0.9	-0.5	-0.3
Alcohol drinker status: Never	0.2	0.3	0.6	-0.5	-0.6	-0.3	-0.2	-0.8	-0.2	-0.4	0.1	-0.7	0.6	0.0	-0.7	-0.2	-0.3	-0.7	-0.8
Number of operations (self-reported)	0.2	0.2	0.5	-0.3	-0.2	0.7	-0.1	-0.7	0.2	-0.5	-0.5	-0.7	-0.0	0.2	-0.5	0.1	-0.7	-0.6	-0.6
Diastolic blood pressure, automated reading	0.2	0.5	1.9	1.4	0.1	1.4	0.4	0.4	0.8	1.1	-0.1	0.6	-0.8	0.6	0.7	0.4	0.3	0.3	0.6
Basal cell carcinoma (self-reported)	0.2	0.2	1.1	0.3	0.1	-0.3	0.0	0.2	0.0	0.1	0.8	0.1	0.3	1.1	0.5	-0.1	0.8	0.2	0.4
Leg fat mass (left)	0.2	0.7	2.7	0.2	0.3	0.8	1.6	0.8	0.6	1.1	1.4	-0.2	-0.4	0.1	0.4	1.6	0.9	0.6	0.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.6	0.0	-1.0	-0.9	-0.7	-0.8	-0.7	-1.3	0.3	0.4	-0.0	-0.6	-0.4	-0.5	0.3	0.2	0.2
Neuroticism (Nagel 2018)	0.1	0.3	0.8	-0.5	-0.4	-0.6	-0.4	-0.4	-0.4	-0.5	-0.3	-0.8	-0.6	-0.9	-0.5	-0.5	-0.5	-0.6	-0.6
Worry (Nagel 2018)	0.1	0.1	0.5	-0.4	0.3	-0.1	0.2	0.3	0.5	0.5	0.4	-0.2	0.2	0.7	-0.0	-0.1	0.0	0.3	0.6
Verbal and Numeric Reasoning (VNR)	0.1	0.3	1.3	0.2	-0.1	-0.4	-0.5	0.0	0.2	-0.6	1.1	0.9	-0.3	-0.3	0.1	-0.4	1.1	0.6	0.7
Prostate Cancer	0.1	0.1	0.7	0.7	-0.0	0.6	-0.0	0.1	0.9	-0.2	-0.2	0.5	-0.2	0.1	0.5	0.3	0.1	-0.0	0.1
HDL Cholesterol	0.1	0.2	1.2	1.1	0.6	-0.1	-0.1	0.0	-0.1	0.2	-0.3	0.0	-0.4	-0.2	0.1	-0.1	-0.3	0.3	0.6
Lupus	0.1	0.2	1.7	-0.6	-0.4	0.3	-0.1	-0.1	-0.1	-0.3	0.0	-0.2	1.3	0.1	-0.5	-0.0	0.1	-0.3	-0.8
Blood Eosinophil Count	0.1	0.8	2.4	-0.1	-0.1	1.4	1.1	0.9	0.7	0.3	1.3	0.8	0.8	0.2	0.8	1.4	1.6	0.3	-0.5
Blood White Count	0.1	0.8	5.9	-0.4	-0.2	1.0	0.6	-0.3	-0.1	-0.2	-0.1	-1.1	-2.4	-0.8	-0.4	0.9	-0.8	-0.8	-1.3
Type 2 Diabetes (T2D) (2018)	0.1	0.1	0.6	-0.0	-0.1	0.6	0.5	0.1	-0.0	0.4	0.7	0.2	-0.3	-0.1	-0.2	0.2	0.4	0.4	0.1
Sensitivity / hurt feelings	0.1	0.2	1.3	-0.7	-0.7	0.4	0.1	0.0	-0.3	-0.1	-0.0	-0.3	-1.1	-0.2	-0.6	-0.1	-0.2	-0.5	-0.6
Systolic blood pressure, automated reading	0.1	0.3	1.1	-0.4	-1.1	-0.3	-0.3	-0.1	-1.0	-0.2	0.3	0.1	0.2	0.9	-0.8	-0.0	0.2	-0.3	-0.1
Taking other prescription medications	0.1	0.2	0.6	-0.2	0.2	0.6	0.6	-0.6	-0.1	0.1	0.0	-0.7	0.4	-0.0	-0.3	0.7	-0.4	-0.2	-0.5
Hayfever, allergic rhinitis or eczema	0.1	0.3	1.0	-0.4	-0.8	-0.4	-0.0	0.4	-0.0	0.2	0.9	0.3	0.6	1.0	-0.1	-0.3	0.7	0.5	0.7
Diabetes (self-reported)	0.1	0.2	0.9	0.3	-0.3	0.4	0.4	0.3	0.0	0.5	1.0	0.5	0.4	0.5	-0.1	0.2	0.8	0.3	0.2
Arm fat mass (right)	0.1	0.5	2.0	0.0	-0.2	0.5	1.4	0.5	0.4	0.7	1.4	-0.1	0.2	-0.0	0.1	1.4	0.9	0.4	0.0
Medication: Ibuprofen	0.1	0.1	0.7	0.1	0.1	-0.6	-0.3	0.0	-0.0	-0.1	0.1	-0.5	-0.9	-0.4	-0.0	-0.2	0.1	-0.2	0.2
Medication: Allopurinol	0.1	0.2	0.7	0.4	-0.5	-0.1	-0.2	-0.2	-0.6	-0.1	0.3	0.3	0.9	-0.1	0.1	-0.5	0.6	0.3	0.4
Heart disease (mother)	0.1	0.2	1.3	0.5	0.8	0.1	0.4	0.2	0.1	0.3	0.2	0.2	1.1	0.3	0.3	0.1	0.3	-0.0	-0.2
Suffer from ‘nerves’	0.1	0.2	0.8	0.1	0.9	0.0	0.5	0.6	0.7	0.4	-0.1	0.2	0.1	-0.1	0.3	0.1	-0.2	0.3	0.3
Mood swings	0.1	0.1	0.7	-0.1	0.0	-0.1	0.6	0.1	0.3	-0.1	0.2	-0.0	-0.3	-0.8	0.2	0.4	-0.0	-0.0	-0.3
Diabetes diagnosed by doctor	0.1	0.1	0.9	-0.0	-0.6	0.1	0.5	-0.0	-0.1	0.3	1.0	-0.0	0.3	-0.0	-0.4	0.1	0.5	0.3	0.1
Arm fat mass (left)	0.1	0.4	1.6	-0.1	-0.4	0.3	1.3	0.3	0.3	0.6	1.3	-0.3	-0.1	-0.1	-0.2	1.2	0.7	0.4	0.1
Mother’s age at death	0.1	0.1	0.5	0.3	-0.5	0.3	0.1	0.5	0.3	0.7	-0.0	-0.3	0.0	0.3	-0.0	0.3	-0.1	0.1	0.3
Average weekly beer plus cider intake	0.1	0.1	0.5	0.6	-0.3	-0.3	-0.4	-0.1	-0.3	0.0	-0.5	0.0	-0.7	-0.4	-0.2	-0.5	-0.3	0.1	0.5
Systolic Blood Pressure	0.0	0.1	0.4	0.1	-0.6	-0.0	-0.4	0.2	-0.5	0.1	0.0	0.0	-0.1	-0.1	-0.4	-0.1	0.2	-0.3	-0.0
Hair Pigment	0.0	0.8	6.1	1.4	-0.7	-0.4	-1.1	0.1	-2.5	-0.2	-0.6	-0.2	-0.4	0.6	-0.4	-1.0	-0.2	-0.5	-0.2
Tanning	0.0	0.6	1.9	-0.7	0.8	-0.5	0.2	-1.0	-0.4	-0.7	-0.7	-0.9	-1.2	0.0	-0.3	0.1	-1.4	-0.7	-1.0

Hub : Genes

MFAP2

Models

Trait associations