[Hub]/) : Traits : Trunk fat-free mass : ← →

chr3:37,692,342-39,280,382

Best TWAS P=1.48e-15 · Best GWAS P=7.96e-14 conditioned to 0.471

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Breast Mammary Tissue	EXOG	0.08	0.06	enet	10	0.05	8.6e-04	-6.5	-8.0	1.5e-15	0.90	0.03	0.95	TRUE
13	GTEx	Testis	EXOG	0.35	0.28	lasso	5	0.26	8.1e-12	-7.5	-7.6	4.1e-14	1.00	0.01	0.99	FALSE
8	GTEx	Esophagus Mucosa	EXOG	0.13	0.05	lasso	3	0.03	5.0e-03	-7.3	-7.5	5.9e-14	0.98	0.02	0.94	FALSE
10	GTEx	Ovary	EXOG	0.33	0.25	lasso	8	0.21	8.1e-06	-7.1	-7.4	1.0e-13	0.90	0.05	0.84	FALSE
5	GTEx	Brain Frontal Cortex BA9	EXOG	0.18	0.08	lasso	4	0.05	1.7e-02	-7.4	-7.4	1.1e-13	0.99	0.02	0.89	FALSE
15	NTR	Blood	ACVR2B	0.02	0.02	lasso	3	0.02	5.6e-07	-7.1	-7.4	1.2e-13	0.95	0.03	0.97	FALSE
12	GTEx	Stomach	EXOG	0.14	0.05	lasso	6	0.02	2.5e-02	-7.3	-7.4	1.3e-13	1.00	0.02	0.97	FALSE
3	GTEx	Brain Cerebellum	EXOG	0.19	0.23	enet	4	0.21	7.7e-07	-7.3	-7.4	1.7e-13	0.99	0.02	0.97	FALSE
14	GTEx	Thyroid	EXOG	0.19	0.20	lasso	3	0.19	2.9e-14	-7.3	-7.3	3.0e-13	0.98	0.01	0.99	FALSE
4	GTEx	Brain Cerebellum	ACVR2B-AS1	0.25	0.07	lasso	6	0.10	8.3e-04	-7.3	-7.3	3.3e-13	0.91	0.02	0.95	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EXOG	0.02	0.02	blup	56	0.01	1.0e-02	-7.1	-7.3	4.1e-13	0.96	0.02	0.87	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	ACVR2B	0.02	0.00	blup	49	0.01	1.6e-02	-7.1	7.2	5.7e-13	-0.92	0.03	0.48	FALSE
17	NTR	Blood	XYLB	0.05	0.06	lasso	3	0.06	6.2e-18	-7.1	-7.2	6.4e-13	0.87	0.07	0.93	FALSE
25	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LOC100128640	0.09	0.05	lasso	2	0.03	1.7e-02	-7.1	7.1	9.6e-13	-0.86	0.02	0.53	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	LOC100128640	0.07	0.03	blup	28	0.03	1.0e-03	-7.5	7.1	1.3e-12	-0.96	0.01	0.98	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ACVR2B	0.08	0.08	enet	15	0.09	9.6e-11	-6.4	7.0	2.8e-12	-0.88	0.16	0.84	FALSE
24	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EXOG	0.14	0.09	blup	56	0.09	9.5e-06	-7.3	-6.9	5.2e-12	0.88	0.01	0.99	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	EXOG	0.10	0.13	lasso	2	0.12	4.8e-15	-7.3	-6.9	5.7e-12	0.98	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	XYLB	0.05	0.03	lasso	4	0.02	2.4e-03	-6.8	6.9	5.8e-12	-0.93	0.02	0.96	FALSE
7	GTEx	Colon Transverse	XYLB	0.08	0.03	enet	15	0.05	1.7e-03	-7.4	6.9	7.0e-12	-0.85	0.02	0.95	FALSE
2	GTEx	Adipose Subcutaneous	EXOG	0.10	0.00	enet	12	0.00	1.3e-01	-7.3	-6.8	8.5e-12	0.68	0.02	0.76	FALSE
16	NTR	Blood	EXOG	0.02	0.03	lasso	6	0.03	1.0e-09	-6.4	6.7	1.5e-11	-0.89	0.17	0.83	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	XYLB	0.03	0.03	blup	82	0.02	5.1e-03	-7.2	6.7	1.9e-11	-0.91	0.01	0.97	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC100128640	0.08	0.02	blup	28	0.03	2.6e-04	-7.4	6.7	2.2e-11	-0.87	0.01	0.98	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	XYLB	0.05	0.06	enet	7	0.05	3.5e-06	-7.2	6.6	3.4e-11	-0.95	0.00	1.00	FALSE
11	GTEx	Pancreas	EXOG	0.22	0.08	enet	15	0.03	2.6e-02	-7.5	-6.5	7.5e-11	0.91	0.03	0.94	FALSE
32	The Cancer Genome Atlas	Thyroid Carcinoma	EXOG	0.11	0.05	blup	56	0.10	9.5e-10	-7.3	-6.2	4.5e-10	0.83	0.02	0.98	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	EXOG	0.04	0.01	blup	56	0.03	2.2e-04	-7.1	-6.2	7.2e-10	0.82	0.02	0.86	FALSE
9	GTEx	Nerve Tibial	EXOG	0.10	0.00	lasso	5	0.00	1.7e-01	-7.3	-5.9	3.1e-09	0.87	0.02	0.88	FALSE
28	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EXOG	0.10	0.02	blup	56	0.03	2.1e-02	-2.7	-5.8	7.3e-09	0.82	0.02	0.57	FALSE
19	YFS	Blood	ACVR2B	0.02	0.00	blup	447	0.00	2.4e-02	-7.1	-5.8	8.3e-09	0.66	0.05	0.80	FALSE
20	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	XYLB	0.06	0.05	blup	82	0.04	5.2e-03	-6.8	5.7	1.1e-08	-0.85	0.03	0.69	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EXOG	0.08	0.02	blup	56	0.06	9.1e-08	-7.5	-5.3	1.3e-07	0.75	0.01	0.99	FALSE