[Hub]/) : Traits : Trunk fat-free mass : ← →

chr4:16,885,388-18,507,692

Best TWAS P=9.36e-68 · Best GWAS P=3.52e-62 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-15.56	17.4	9.4e-68	-0.81	0.04	0.81	TRUE
25	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-14.84	13.9	4.4e-44	-0.83	0.03	0.89	TRUE
6	GTEx	Artery Tibial	DCAF16	0.16	0.16	lasso	5	0.13	1.5e-10	11.41	12.8	1.1e-37	-0.36	1.00	0.00	TRUE
17	GTEx	Skin Not Sun Exposed Suprapubic	DCAF16	0.16	0.08	lasso	5	0.12	4.4e-07	11.09	12.2	2.6e-34	-0.35	0.64	0.03	TRUE
35	The Cancer Genome Atlas	Lung Adenocarcinoma	NCAPG	0.06	0.02	blup	34	0.04	1.0e-05	-14.91	-9.7	4.1e-22	0.68	0.05	0.63	TRUE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	NCAPG	0.03	0.04	enet	5	0.04	8.1e-09	-0.76	-6.0	1.4e-09	0.55	0.95	0.05	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FAM184B	0.14	0.25	enet	21	0.24	2.0e-28	-4.88	5.3	1.2e-07	-0.14	1.00	0.00	TRUE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	11.41	16.2	4.0e-59	-0.64	0.07	0.82	FALSE
19	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	10.07	15.6	1.4e-54	-0.66	0.06	0.50	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	11.19	15.6	1.4e-54	-0.65	0.14	0.79	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-14.91	-14.9	2.6e-50	0.88	0.03	0.56	FALSE
8	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-14.77	14.8	1.4e-49	-0.76	0.05	0.54	FALSE
21	GTEx	Thyroid	DCAF16	0.11	0.02	lasso	5	0.03	2.3e-03	10.07	14.7	3.2e-49	-0.54	0.16	0.71	FALSE
37	The Cancer Genome Atlas	Prostate Adenocarcinoma	DCAF16	0.04	0.04	blup	31	0.04	2.2e-05	10.07	14.6	5.3e-48	-0.58	0.27	0.22	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-14.84	-14.5	1.7e-47	0.84	0.81	0.19	FALSE
7	GTEx	Breast Mammary Tissue	DCAF16	0.12	0.08	lasso	4	0.10	6.4e-06	10.07	13.4	3.9e-41	-0.52	0.16	0.60	FALSE
28	The Cancer Genome Atlas	Colon Adenocarcinoma	NCAPG	0.08	0.04	blup	34	0.09	1.1e-05	-14.91	-13.2	8.7e-40	0.84	0.02	0.97	FALSE
38	The Cancer Genome Atlas	Prostate Adenocarcinoma	NCAPG	0.02	0.02	blup	34	0.02	3.4e-03	-13.60	-12.5	4.3e-36	0.76	0.01	0.83	FALSE
20	GTEx	Stomach	DCAF16	0.21	0.04	lasso	6	0.02	5.6e-02	11.19	12.3	1.6e-34	-0.26	0.19	0.04	FALSE
15	GTEx	Nerve Tibial	DCAF16	0.16	0.14	lasso	3	0.14	2.8e-10	10.07	11.6	4.8e-31	-0.37	0.99	0.01	FALSE
26	YFS	Blood	DCAF16	0.02	0.02	lasso	1	0.01	1.1e-04	11.41	11.4	3.7e-30	-0.25	0.84	0.04	FALSE
18	GTEx	Skin Sun Exposed Lower leg	DCAF16	0.14	0.12	enet	14	0.12	5.4e-10	10.07	11.4	5.7e-30	-0.28	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	DCAF16	0.19	0.06	enet	10	0.11	3.9e-06	10.07	11.3	9.7e-30	-0.35	0.27	0.51	FALSE
12	GTEx	Esophagus Mucosa	DCAF16	0.10	0.02	lasso	4	0.02	8.3e-03	10.07	10.8	2.7e-27	-0.37	0.13	0.41	FALSE
9	GTEx	Breast Mammary Tissue (Female)	DCAF16	0.16	0.13	lasso	2	0.06	7.8e-03	10.07	10.2	1.2e-24	-0.27	0.06	0.08	FALSE
16	GTEx	Pituitary	DCAF16	0.27	0.20	enet	15	0.19	1.3e-05	10.07	10.1	6.4e-24	-0.38	0.07	0.37	FALSE
13	GTEx	Esophagus Muscularis	DCAF16	0.16	0.14	lasso	3	0.14	9.3e-09	10.07	9.9	5.3e-23	-0.27	0.99	0.00	FALSE
3	GTEx	Adipose Subcutaneous	DCAF16	0.21	0.15	lasso	3	0.17	5.1e-14	10.07	9.8	7.5e-23	-0.24	1.00	0.00	FALSE
23	ROSMAP	Brain Pre-frontal Cortex	FAM184B	0.17	0.14	enet	31	0.18	5.1e-23	-5.54	-7.8	5.1e-15	0.26	1.00	0.00	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	MED28	0.02	0.01	bslmm	411	0.00	1.9e-01	-5.32	7.5	6.3e-14	-0.30	0.22	0.03	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MED28	0.07	0.09	enet	9	0.11	7.1e-13	-5.54	5.6	1.7e-08	-0.18	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FAM184B	0.02	0.03	lasso	2	0.02	2.6e-03	-5.55	-5.6	1.8e-08	0.16	0.24	0.03	FALSE
39	The Cancer Genome Atlas	Stomach Adenocarcinoma	LAP3	0.07	0.03	blup	36	0.06	5.3e-05	-3.58	-5.5	3.2e-08	0.15	0.02	0.97	FALSE
33	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	MED28	0.08	0.05	blup	34	0.05	2.9e-03	-5.31	5.5	3.7e-08	-0.17	0.02	0.76	FALSE
11	GTEx	Colon Transverse	MED28	0.13	0.05	lasso	3	0.02	5.8e-02	-4.68	5.3	1.1e-07	-0.11	0.20	0.04	FALSE
22	NTR	Blood	MED28	0.09	0.18	lasso	2	0.18	3.7e-54	-5.17	5.3	1.1e-07	-0.16	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Lung Adenocarcinoma	MED28	0.02	0.01	blup	34	0.01	8.5e-03	-5.27	5.2	2.0e-07	-0.14	0.02	0.82	FALSE
36	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LAP3	0.02	0.02	lasso	4	0.01	2.2e-02	-5.20	-5.2	2.0e-07	0.14	0.02	0.81	FALSE
14	GTEx	Muscle Skeletal	MED28	0.05	0.03	enet	8	0.02	3.1e-03	-5.17	5.2	2.3e-07	-0.14	0.56	0.02	FALSE
10	GTEx	Cells Transformed fibroblasts	LAP3	0.20	0.12	lasso	6	0.13	3.0e-10	-5.27	-5.2	2.4e-07	0.13	1.00	0.00	FALSE
40	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MED28	0.08	0.05	lasso	3	0.05	8.7e-03	-4.68	5.1	2.9e-07	-0.12	0.02	0.69	FALSE