[Hub]/) : Traits : Trunk fat-free mass : ← →

chr4:305,291-2,437,290

Best TWAS P=7.49e-19 · Best GWAS P=1.72e-16 conditioned to 0.00229

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
62	NTR	Blood	CRIPAK	0.13	0.09	enet	31	0.15	1.5e-46	-4.8	-8.9	7.5e-19	0.00	1.00	0.00	TRUE
65	NTR	Blood	TACC3	0.05	0.03	lasso	9	0.04	2.7e-13	-7.3	8.5	1.6e-17	0.71	0.40	0.60	TRUE
35	GTEx	Muscle Skeletal	FGFRL1	0.14	0.08	lasso	4	0.06	3.7e-06	-7.8	7.3	3.5e-13	0.01	0.00	1.00	TRUE
64	NTR	Blood	SLBP	0.04	0.02	lasso	5	0.02	2.8e-08	-7.4	8.1	8.2e-16	0.82	0.04	0.96	FALSE
63	NTR	Blood	KIAA1530	0.19	0.04	blup	345	0.10	9.1e-32	-6.0	-8.0	9.4e-16	0.08	1.00	0.00	FALSE
33	GTEx	Lung	CRIPAK	0.61	0.22	enet	46	0.41	1.1e-33	-5.0	-7.9	2.2e-15	0.02	1.00	0.00	FALSE
12	GTEx	Brain Hippocampus	CRIPAK	0.48	0.22	lasso	4	0.23	4.0e-06	-5.4	-7.9	3.3e-15	0.00	0.18	0.14	FALSE
58	METSIM	Adipose	CRIPAK	0.28	0.16	bslmm	335	0.25	2.7e-37	-4.9	-7.8	4.7e-15	-0.01	1.00	0.00	FALSE
39	GTEx	Nerve Tibial	CRIPAK	0.50	0.11	enet	76	0.38	1.1e-28	-5.4	-7.7	1.2e-14	-0.08	1.00	0.00	FALSE
11	GTEx	Brain Cortex	CRIPAK	0.34	0.10	lasso	6	0.18	9.5e-06	-5.0	-7.7	1.5e-14	0.03	0.19	0.10	FALSE
18	GTEx	Breast Mammary Tissue (Female)	CRIPAK	0.32	0.17	enet	29	0.26	2.7e-08	-5.2	-7.6	4.1e-14	0.01	0.53	0.03	FALSE
69	YFS	Blood	CRIPAK	0.35	0.27	bslmm	301	0.33	6.0e-112	-5.4	-7.4	1.4e-13	-0.03	1.00	0.00	FALSE
70	YFS	Blood	SLBP	0.10	0.12	lasso	3	0.12	1.2e-35	-7.3	7.3	2.7e-13	0.60	0.64	0.36	FALSE
22	GTEx	Colon Transverse	TMEM129	0.23	0.05	lasso	4	0.03	1.8e-02	-7.3	7.3	3.4e-13	0.51	0.09	0.10	FALSE
44	GTEx	Pancreas	CRIPAK	0.34	0.13	lasso	6	0.27	1.0e-11	-5.4	-7.2	4.6e-13	0.01	0.84	0.01	FALSE
56	GTEx	Whole Blood	CRIPAK	0.38	0.17	lasso	9	0.28	3.4e-26	-5.4	-7.1	1.6e-12	0.02	1.00	0.00	FALSE
73	The Cancer Genome Atlas	Breast Invasive Carcinoma	CRIPAK	0.22	0.11	blup	28	0.14	5.6e-28	-5.4	-7.0	2.1e-12	0.01	0.00	1.00	FALSE
42	GTEx	Ovary	CRIPAK	0.43	0.27	enet	19	0.32	9.0e-09	-5.0	-7.0	3.4e-12	0.03	0.46	0.06	FALSE
43	GTEx	Pancreas	TMEM129	0.20	0.19	lasso	3	0.14	1.5e-06	-7.3	7.0	3.5e-12	0.58	0.60	0.34	FALSE
57	GTEx	Whole Blood	AC016773.1	0.27	0.21	enet	8	0.22	1.2e-19	-7.3	7.0	3.5e-12	0.53	0.64	0.36	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CRIPAK	0.31	0.15	enet	34	0.26	1.2e-31	-5.1	-6.9	5.3e-12	0.04	1.00	0.00	FALSE
60	METSIM	Adipose	TMEM129	0.11	0.09	lasso	8	0.09	3.3e-13	-7.3	6.9	5.5e-12	0.57	0.65	0.35	FALSE
53	GTEx	Thyroid	AC016773.1	0.11	0.07	enet	7	0.06	3.9e-05	-7.4	6.8	7.8e-12	0.52	0.51	0.27	FALSE
36	GTEx	Muscle Skeletal	CRIPAK	0.25	0.11	enet	32	0.18	7.6e-18	-5.0	-6.8	8.8e-12	0.03	1.00	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	CRIPAK	0.47	0.24	lasso	12	0.31	1.3e-16	-5.0	-6.8	8.9e-12	0.02	1.00	0.00	FALSE
34	GTEx	Lung	RP11-20I20.4	0.07	0.00	lasso	3	0.01	6.0e-02	-6.0	-6.8	1.0e-11	0.03	0.14	0.03	FALSE
55	GTEx	Whole Blood	TACC3	0.11	0.05	enet	7	0.06	2.8e-06	-4.8	6.8	1.3e-11	0.59	0.80	0.17	FALSE
61	METSIM	Adipose	UVSSA	0.26	0.04	bslmm	366	0.12	9.0e-18	1.8	-6.8	1.4e-11	0.02	0.98	0.02	FALSE
9	GTEx	Brain Cerebellum	CRIPAK	0.37	0.09	enet	24	0.31	8.8e-10	-5.2	-6.7	1.7e-11	-0.01	0.40	0.06	FALSE
13	GTEx	Brain Hypothalamus	CRIPAK	0.22	0.00	lasso	5	0.01	2.1e-01	-6.0	-6.7	1.9e-11	0.02	0.06	0.08	FALSE
16	GTEx	Brain Putamen basal ganglia	CRIPAK	0.30	0.00	enet	25	0.10	1.9e-03	-4.5	-6.7	2.1e-11	0.11	0.06	0.10	FALSE
95	The Cancer Genome Atlas	Thyroid Carcinoma	CRIPAK	0.38	0.22	enet	12	0.25	5.4e-24	-5.4	-6.7	2.3e-11	0.01	0.00	1.00	FALSE
15	GTEx	Brain Nucleus accumbens basal ganglia	CRIPAK	0.34	0.13	lasso	6	0.25	2.7e-07	-5.0	-6.7	2.5e-11	0.05	0.20	0.05	FALSE
68	ROSMAP	Brain Pre-frontal Cortex	AC016773.1	0.12	0.06	lasso	3	0.10	3.0e-12	-7.4	6.7	2.8e-11	0.52	0.76	0.24	FALSE
87	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TACC3	0.09	0.08	enet	7	0.11	2.7e-05	-7.3	6.7	2.8e-11	0.52	0.13	0.23	FALSE
77	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CRIPAK	0.28	0.16	blup	28	0.19	3.2e-21	-5.4	-6.7	2.9e-11	0.03	0.00	1.00	FALSE
10	GTEx	Brain Cortex	TACC3	0.26	0.13	lasso	4	0.17	1.7e-05	-7.3	6.6	4.3e-11	0.52	0.24	0.30	FALSE
31	GTEx	Heart Atrial Appendage	CRIPAK	0.31	0.26	enet	23	0.33	2.1e-15	-5.0	-6.6	5.0e-11	0.03	1.00	0.00	FALSE
8	GTEx	Brain Caudate basal ganglia	CRIPAK	0.27	0.00	lasso	2	0.02	9.3e-02	-6.0	-6.6	5.3e-11	0.01	0.06	0.06	FALSE
19	GTEx	Cells EBV-transformed lymphocytes	CRIPAK	0.49	0.27	lasso	8	0.35	2.9e-12	-5.0	-6.6	5.5e-11	0.05	0.84	0.01	FALSE
23	GTEx	Colon Transverse	CRIPAK	0.33	0.10	enet	22	0.24	5.8e-12	-5.4	-6.5	6.8e-11	0.03	0.97	0.00	FALSE
24	GTEx	Colon Transverse	RP11-20I20.4	0.17	0.05	lasso	3	0.05	2.3e-03	-6.0	-6.5	8.7e-11	0.01	0.43	0.03	FALSE
27	GTEx	Esophagus Mucosa	CRIPAK	0.49	0.14	enet	28	0.40	6.8e-29	-5.0	-6.4	1.5e-10	0.00	0.99	0.01	FALSE
79	The Cancer Genome Atlas	Brain Lower Grade Glioma	CRIPAK	0.31	0.11	enet	10	0.18	1.5e-19	-5.4	-6.4	1.5e-10	-0.03	0.00	1.00	FALSE
17	GTEx	Breast Mammary Tissue	CRIPAK	0.42	0.12	enet	35	0.39	5.2e-21	-5.0	-6.4	1.6e-10	0.02	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CRIPAK	0.42	0.11	enet	42	0.34	9.0e-29	-5.2	-6.4	1.7e-10	0.04	1.00	0.00	FALSE
5	GTEx	Artery Aorta	UVSSA	0.33	0.06	enet	30	0.28	7.2e-16	-6.0	-6.4	1.8e-10	0.01	0.36	0.62	FALSE
26	GTEx	Esophagus Gastroesophageal Junction	CRIPAK	0.33	0.20	lasso	5	0.30	1.4e-11	-5.0	-6.4	2.0e-10	0.02	0.99	0.00	FALSE
54	GTEx	Uterus	CRIPAK	0.52	0.34	lasso	3	0.33	1.7e-07	-6.0	-6.4	2.1e-10	0.01	0.23	0.06	FALSE
97	The Cancer Genome Atlas	Thyroid Carcinoma	TMEM129	0.20	0.21	lasso	5	0.24	3.5e-23	-3.9	6.4	2.1e-10	0.49	0.99	0.01	FALSE
74	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA1530	0.13	0.01	blup	48	0.03	4.9e-07	-5.2	-6.3	2.4e-10	-0.05	0.00	1.00	FALSE
6	GTEx	Artery Aorta	CRIPAK	0.31	0.20	enet	34	0.30	2.8e-17	-5.0	-6.3	3.6e-10	0.01	1.00	0.00	FALSE
29	GTEx	Esophagus Muscularis	CRIPAK	0.38	0.14	enet	34	0.30	2.6e-18	-5.0	-6.3	3.7e-10	0.05	1.00	0.00	FALSE
75	The Cancer Genome Atlas	Colon Adenocarcinoma	CRIPAK	0.38	0.16	blup	28	0.21	2.8e-12	-5.4	-6.2	4.2e-10	0.01	0.00	1.00	FALSE
67	ROSMAP	Brain Pre-frontal Cortex	CRIPAK	0.31	0.23	lasso	12	0.40	6.4e-55	-4.9	-6.2	4.5e-10	0.01	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	UVSSA	0.46	0.05	lasso	11	0.24	1.1e-12	-6.0	-6.2	5.4e-10	0.01	0.85	0.04	FALSE
21	GTEx	Colon Sigmoid	CRIPAK	0.40	0.21	lasso	7	0.30	4.7e-11	-6.0	-6.2	6.0e-10	0.06	0.72	0.01	FALSE
78	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CRIPAK	0.21	0.10	enet	9	0.15	1.3e-16	-5.4	-6.2	6.1e-10	0.00	0.00	1.00	FALSE
90	The Cancer Genome Atlas	Rectum Adenocarcinoma	CRIPAK	0.37	0.07	lasso	2	0.12	1.2e-03	-5.4	-6.2	7.6e-10	0.03	0.00	0.83	FALSE
41	GTEx	Ovary	UVSSA	0.33	0.10	enet	12	0.32	1.5e-08	-6.0	-6.0	2.1e-09	0.02	0.11	0.06	FALSE
25	GTEx	Esophagus Gastroesophageal Junction	UVSSA	0.30	0.00	enet	23	0.08	1.1e-03	-5.0	-6.0	2.7e-09	0.09	0.28	0.04	FALSE
86	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CRIPAK	0.41	0.10	lasso	4	0.08	5.2e-04	-5.4	-5.9	3.4e-09	0.02	0.00	0.98	FALSE
47	GTEx	Skin Sun Exposed Lower leg	CRIPAK	0.36	0.09	enet	40	0.35	8.7e-30	-5.2	-5.9	3.5e-09	0.03	1.00	0.00	FALSE
51	GTEx	Thyroid	TMEM129	0.44	0.31	lasso	7	0.34	1.2e-26	-4.0	5.9	4.0e-09	0.46	1.00	0.00	FALSE
66	ROSMAP	Brain Pre-frontal Cortex	UVSSA	0.31	0.05	blup	350	0.23	7.1e-29	1.8	-5.9	4.2e-09	-0.05	0.75	0.25	FALSE
14	GTEx	Brain Nucleus accumbens basal ganglia	UVSSA	0.24	0.00	enet	33	0.04	2.8e-02	0.8	-5.9	4.6e-09	-0.10	0.07	0.05	FALSE
45	GTEx	Skin Not Sun Exposed Suprapubic	CRIPAK	0.39	0.14	lasso	13	0.34	1.5e-19	-5.0	-5.8	4.9e-09	0.01	0.92	0.06	FALSE
48	GTEx	Spleen	AC016773.1	0.42	0.21	lasso	7	0.16	8.6e-05	-7.4	5.8	7.4e-09	0.50	0.11	0.17	FALSE
80	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CRIPAK	0.13	0.06	blup	29	0.08	1.2e-04	-5.4	-5.8	7.6e-09	0.01	0.00	0.98	FALSE
91	The Cancer Genome Atlas	Soft Tissue Sarcoma	CRIPAK	0.20	0.10	lasso	5	0.15	2.2e-09	-5.0	-5.8	8.6e-09	0.07	0.01	0.98	FALSE
7	GTEx	Artery Tibial	CRIPAK	0.42	0.09	enet	50	0.34	1.3e-27	2.1	-5.8	9.2e-09	0.02	1.00	0.00	FALSE
72	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CRIPAK	0.11	0.07	lasso	4	0.05	2.0e-05	-5.4	-5.8	9.2e-09	0.00	0.00	1.00	FALSE
82	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CRIPAK	0.14	0.05	lasso	4	0.07	6.1e-08	-5.4	-5.7	1.0e-08	0.01	0.00	1.00	FALSE
37	GTEx	Muscle Skeletal	AC016773.1	0.12	0.01	lasso	7	0.02	2.5e-03	-7.3	5.7	1.1e-08	0.27	0.68	0.17	FALSE
71	YFS	Blood	TACC3	0.22	0.24	lasso	11	0.27	1.4e-87	-7.3	5.7	1.1e-08	0.34	0.65	0.35	FALSE
88	The Cancer Genome Atlas	Prostate Adenocarcinoma	CRIPAK	0.27	0.17	enet	4	0.18	2.7e-18	-5.4	-5.7	1.5e-08	0.00	0.00	1.00	FALSE
28	GTEx	Esophagus Muscularis	UVSSA	0.35	0.03	enet	33	0.16	3.5e-10	-5.0	-5.6	2.5e-08	0.03	0.93	0.01	FALSE
38	GTEx	Nerve Tibial	TMEM129	0.31	0.24	enet	13	0.28	5.0e-20	-3.9	5.5	4.7e-08	0.38	1.00	0.00	FALSE
96	The Cancer Genome Atlas	Thyroid Carcinoma	FAM53A	0.05	0.03	blup	56	0.04	1.8e-04	4.0	5.4	6.3e-08	0.79	0.01	0.95	FALSE
83	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	KIAA1530	0.12	0.02	blup	47	0.03	4.2e-04	-5.1	-5.4	6.4e-08	-0.05	0.00	0.97	FALSE
81	The Cancer Genome Atlas	Lung Adenocarcinoma	CRIPAK	0.09	0.07	lasso	1	0.06	1.5e-07	-5.4	-5.4	8.4e-08	-0.01	0.00	1.00	FALSE
49	GTEx	Stomach	CRIPAK	0.43	0.22	enet	46	0.35	1.4e-17	-5.0	-5.3	9.0e-08	0.06	1.00	0.00	FALSE
93	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CRIPAK	0.57	0.07	enet	9	0.23	6.7e-07	-5.0	-5.3	1.1e-07	0.06	0.00	0.95	FALSE
85	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CRIPAK	0.34	0.30	lasso	3	0.27	7.5e-12	-5.4	-5.3	1.2e-07	0.00	0.00	1.00	FALSE
94	The Cancer Genome Atlas	Stomach Adenocarcinoma	CRIPAK	0.17	0.07	blup	29	0.08	1.3e-06	-3.9	-5.3	1.2e-07	0.08	0.02	0.97	FALSE
40	GTEx	Nerve Tibial	CTBP1-AS2	0.18	0.03	lasso	5	0.03	3.2e-03	-4.9	-5.3	1.3e-07	0.00	0.61	0.02	FALSE
32	GTEx	Heart Left Ventricle	CRIPAK	0.19	0.05	enet	24	0.21	3.4e-11	-5.0	-5.3	1.4e-07	0.10	0.65	0.02	FALSE
30	GTEx	Esophagus Muscularis	RP11-20I20.4	0.19	0.09	lasso	3	0.10	1.9e-06	3.7	-5.3	1.5e-07	0.02	0.78	0.01	FALSE
20	GTEx	Cells Transformed fibroblasts	CRIPAK	0.35	0.06	enet	33	0.22	3.0e-16	-5.4	-5.2	1.9e-07	0.09	1.00	0.00	FALSE
59	METSIM	Adipose	SPON2	0.06	0.06	lasso	8	0.05	2.2e-08	-5.0	-5.2	1.9e-07	0.02	1.00	0.00	FALSE
50	GTEx	Thyroid	FGFRL1	0.39	0.05	enet	47	0.14	6.9e-11	3.1	5.2	2.0e-07	0.04	0.98	0.00	FALSE
84	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TMEM129	0.05	0.03	lasso	4	0.02	8.5e-04	4.6	-5.2	2.3e-07	-0.69	0.12	0.49	FALSE
89	The Cancer Genome Atlas	Prostate Adenocarcinoma	TMEM129	0.12	0.01	blup	47	0.05	2.5e-06	-7.3	5.2	2.3e-07	0.18	0.12	0.16	FALSE
52	GTEx	Thyroid	CRIPAK	0.51	0.14	enet	44	0.34	6.1e-27	1.8	-5.2	2.6e-07	0.04	1.00	0.00	FALSE
46	GTEx	Skin Sun Exposed Lower leg	TMEM129	0.22	0.16	lasso	5	0.17	5.5e-14	-4.0	5.2	2.7e-07	0.35	1.00	0.00	FALSE
76	The Cancer Genome Atlas	Esophageal Carcinoma	CRIPAK	0.39	0.15	blup	28	0.15	1.8e-05	-5.4	-5.1	3.0e-07	-0.06	0.00	0.98	FALSE
92	The Cancer Genome Atlas	Soft Tissue Sarcoma	TMEM129	0.09	0.04	lasso	2	0.03	3.8e-03	-4.8	-5.1	3.1e-07	-0.51	0.02	0.30	FALSE