Best TWAS P=3.82e-36 · Best GWAS P=6.91e-47 conditioned to 2.86e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -11.2 | -9.0 | 1.9e-19 | 0.31 | 0.52 | 0.41 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 9.4 | 9.6 | 6.0e-22 | -0.22 | 0.06 | 0.25 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -12.7 | 12.6 | 3.8e-36 | -0.38 | 0.32 | 0.11 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 12.2 | -12.5 | 9.5e-36 | 0.31 | 0.49 | 0.28 | TRUE |