Best TWAS P=7.45e-25 · Best GWAS P=1.12e-26 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 6.1e-04 | -10.1 | 10.3 | 7.5e-25 | -0.97 | 0.02 | 0.96 | TRUE |
| 6 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 3.4e-02 | 4.7 | -6.6 | 4.0e-11 | 0.12 | 0.01 | 0.66 | TRUE |
| 2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 1.9e-04 | -5.0 | 7.5 | 9.6e-14 | -0.74 | 0.10 | 0.89 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | VTA1 | 0.03 | 0.02 | blup | 66 | 0.02 | 1.7e-03 | 6.4 | -6.3 | 2.4e-10 | 0.09 | 0.17 | 0.31 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NMBR | 0.03 | 0.03 | blup | 46 | 0.02 | 3.6e-05 | 4.9 | -6.2 | 5.4e-10 | 0.14 | 0.87 | 0.04 | FALSE |
| 3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 2.6e-03 | -3.0 | -5.7 | 9.2e-09 | 0.40 | 0.34 | 0.05 | FALSE |