TWAS hub - SNX13

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1930	0.0490	7.5e-09	0.155	NA	0.093	NA	0.127	1.2e-12	NA	4.6e-08	NA	1.5e-10
2	GTEx	Adipose Visceral Omentum	0.2330	0.0600	2.5e-06	0.096	NA	0.128	NA	0.111	1.1e-05	NA	3.5e-07	NA	2.2e-06
3	GTEx	Breast Mammary Tissue	0.2050	0.0620	2.7e-05	0.168	NA	0.151	NA	0.169	5.4e-09	NA	3.5e-08	NA	4.9e-09
4	GTEx	Breast Mammary Tissue (Male)	0.1233	0.0862	7.4e-02	0.056	NA	-0.011	NA	0.024	2.1e-02	NA	6.9e-01	NA	9.0e-02
5	GTEx	Breast Mammary Tissue (Female)	0.0459	0.0562	2.5e-01	-0.006	NA	-0.009	NA	0.028	5.5e-01	NA	7.3e-01	NA	4.9e-02
6	GTEx	Colon Transverse	0.1360	0.0540	1.9e-03	0.068	NA	0.060	NA	0.068	3.7e-04	NA	7.8e-04	NA	3.8e-04
7	GTEx	Nerve Tibial	0.1132	0.0387	1.0e-04	0.092	NA	0.040	NA	0.060	4.5e-07	NA	7.4e-04	NA	4.8e-05
8	GTEx	Small Intestine Terminal Ileum	0.2930	0.1150	6.6e-03	-0.011	NA	0.018	NA	-0.013	6.7e-01	NA	1.3e-01	NA	9.0e-01
9	GTEx	Testis	0.2120	0.0630	3.5e-06	0.140	NA	0.131	NA	0.126	9.2e-07	NA	2.0e-06	NA	3.4e-06
10	METSIM	Adipose	0.0696	0.0179	5.2e-09	0.090	0.055	0.079	0.068	0.093	2.2e-13	1.2e-08	7.3e-12	2.4e-10	1.0e-13
11	TCGA	Colon Adenocarcinoma	0.1510	0.0540	1.4e-08	0.165	0.158	0.160	NA	0.178	8.1e-10	2.0e-09	1.6e-09	NA	1.7e-10
12	TCGA	Thyroid Carcinoma	0.0760	0.0380	3.4e-03	0.004	0.023	0.011	NA	0.000	1.3e-01	2.3e-03	2.6e-02	NA	2.9e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Heel bone mineral density (BMD) T-score, automated (left)	5.1	11.5	19.4	4.0	3.5	3.4	3.6	3.3	-1.8	4.4	-1.9	4.4	3.8	-3.8	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	4.6	10.6	15.9	3.8	3.6	2.8	3.5	2.7	-2.1	3.9	-2.5	4.0	3.8	-3.7	-1.7
Number of live births	4.5	6.4	10.7	-2.9	-2.2	-2.6	-2.8	-2.4	1.5	-3.2	1.9	-3.3	-3.0	2.7	0.1
Trunk fat-free mass	4.2	23.9	36.0	5.5	3.5	4.2	4.8	4.1	-5.0	5.7	-4.1	5.9	5.6	-6.0	-2.9
Trunk predicted mass	4.2	24.0	36.1	5.6	3.6	4.2	4.8	4.1	-4.9	5.8	-4.1	6.0	5.6	-6.0	-2.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	4.1	8.7	14.4	-3.6	-2.9	-2.8	-2.8	-2.7	2.5	-3.8	2.7	-3.5	-3.4	2.9	0.4
HDL Cholesterol	4.0	6.7	14.5	-2.8	-1.9	-2.0	-2.1	-2.1	0.1	-3.6	2.6	-3.8	-3.1	2.9	1.9
Osteoporosis (self-reported)	4.0	5.0	10.0	-2.6	-2.9	-2.9	-1.6	-3.2	1.8	-2.8	0.0	-2.5	-2.2	1.2	-0.2
Arm fat-free mass (right)	3.8	19.6	29.9	4.9	3.0	3.8	4.2	3.8	-4.8	5.1	-3.7	5.3	5.1	-5.5	-3.1
Arm predicted mass (right)	3.6	18.7	30.4	4.8	3.0	3.7	4.1	3.6	-4.5	4.9	-3.7	5.2	4.8	-5.5	-3.1
Pulse wave peak to peak time	3.4	4.0	6.5	2.4	2.2	2.3	2.1	2.4	-1.0	2.5	-0.3	2.5	2.5	-1.5	0.0
Emphysema/chronic bronchitis	3.4	3.8	7.1	2.2	2.6	2.7	2.3	2.4	-1.7	1.6	0.2	1.6	1.9	-1.8	1.0
Whole body fat-free mass	3.4	19.2	27.9	5.0	3.3	3.8	4.5	3.7	-4.4	5.1	-3.6	5.2	5.1	-5.3	-2.6
Whole body water mass	3.4	19.4	28.0	5.1	3.3	3.9	4.5	3.8	-4.5	5.1	-3.6	5.3	5.1	-5.3	-2.6
HbA1C	3.2	3.6	6.9	-1.9	-1.6	-1.2	-1.2	-1.4	2.6	-2.6	2.1	-2.5	-1.8	1.9	1.1
Length of working week for main job	3.2	3.5	7.2	2.3	1.8	1.9	2.4	1.9	-0.5	2.7	-1.2	2.5	2.1	-1.3	-0.0
Arm fat-free mass (left)	3.2	16.3	29.4	4.3	2.5	3.2	3.6	3.1	-4.5	4.5	-3.7	4.9	4.4	-5.4	-3.2
Arm predicted mass (left)	3.2	16.2	28.5	4.4	2.6	3.3	3.7	3.1	-4.3	4.5	-3.8	4.8	4.5	-5.3	-3.1
Lung FVC	3.1	15.8	43.6	-3.4	-1.5	-1.7	-2.2	-1.8	6.6	-4.5	5.9	-4.4	-4.2	4.2	3.5
Illnesses of father: Heart disease	3.0	4.1	9.0	2.1	1.2	2.0	1.8	2.0	-0.8	2.4	-3.0	2.6	2.5	-2.1	0.1
Age started oral contraceptive pill	3.0	3.7	10.9	-1.9	-3.3	-1.9	-2.0	-1.7	1.5	-1.9	1.2	-2.1	-1.6	2.2	0.7
Pulse wave Arterial Stiffness index	2.7	3.1	4.9	-2.1	-2.0	-2.1	-1.9	-2.1	0.7	-2.2	0.1	-2.1	-2.2	1.1	-0.4
Risk taking	2.7	4.0	6.4	-2.3	-2.2	-2.5	-2.3	-2.5	1.7	-1.8	1.1	-1.9	-2.3	1.8	-0.3
Had menopause	2.6	3.2	6.4	-1.8	-2.5	-2.5	-2.0	-2.4	0.4	-1.4	1.3	-1.5	-1.6	1.7	-1.3
Time employed in main current job	2.6	3.0	8.4	1.7	0.9	0.7	1.3	1.0	-1.7	2.2	-2.9	2.1	1.7	-1.6	-1.8
Medication: Lansoprazole	2.6	3.0	14.5	-0.5	0.0	0.5	-0.1	0.4	2.2	-1.1	1.6	-1.5	-1.0	2.9	3.8
Migraine (self-reported)	2.6	3.2	6.1	2.5	1.0	2.4	1.9	2.1	-0.9	2.0	-0.7	2.0	2.5	-1.4	-0.3
Illnesses of siblings: Diabetes	2.6	3.2	6.5	2.0	1.5	2.4	2.1	2.5	-0.8	1.8	1.1	1.6	2.0	-1.2	1.6
Basal metabolic rate	2.6	14.2	21.8	4.3	2.6	3.2	3.8	3.1	-3.8	4.3	-3.2	4.5	4.3	-4.7	-2.4
Ovarian Cancer	2.3	3.0	6.7	-1.5	-0.5	-1.4	-1.0	-1.5	2.1	-1.9	2.6	-2.1	-1.7	2.5	0.1
Hand grip strength (left)	2.3	6.2	10.5	3.1	2.1	2.4	2.3	2.3	-1.6	3.2	-2.5	3.2	2.7	-2.3	-1.0
Impedance of arm (right)	2.2	10.1	18.4	-3.4	-1.8	-2.5	-2.4	-2.6	3.2	-4.1	2.5	-4.1	-3.6	4.3	2.3
Standing height	2.2	22.1	30.8	5.2	4.0	4.3	5.0	4.1	-5.2	5.0	-4.0	5.4	5.2	-5.5	-2.8
Birth weight of first child	2.2	4.0	7.8	2.4	2.4	2.8	2.2	2.8	-1.3	1.8	0.4	1.7	2.1	-1.2	1.4
Birth weight	2.2	4.8	14.7	1.9	0.4	1.2	1.1	1.1	-3.0	2.8	-1.4	3.0	2.0	-3.8	-1.8
Breast cancer (self-reported)	2.2	2.6	5.1	-1.6	-1.7	-1.1	-1.3	-1.0	1.6	-2.2	0.9	-2.3	-1.3	2.3	1.4
Leg predicted mass (right)	2.2	11.5	16.2	4.0	2.9	3.0	3.8	2.9	-3.3	3.9	-2.6	4.0	3.9	-3.9	-1.6
Alcohol drinker status: Never	2.2	2.6	5.0	-1.6	-2.2	-1.1	-1.5	-1.1	1.5	-1.6	1.5	-1.7	-1.9	2.0	1.2
Alzheimer’s Disease (in father)	2.1	2.3	6.1	-1.7	-1.2	-1.2	-1.5	-1.3	0.9	-2.5	0.7	-2.4	-1.8	1.0	0.5
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	4.5	2.1	1.7	1.3	1.6	1.6	-1.1	2.0	-1.3	1.9	1.9	-0.7	-0.3
Financial difficulties in last 2 years	2.1	2.8	7.2	-1.8	-1.8	-1.1	-1.4	-0.9	1.1	-1.7	2.7	-1.8	-2.1	1.3	1.5
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	4.9	-1.7	-0.5	-1.1	-1.5	-0.9	1.1	-2.1	1.5	-2.2	-2.0	2.1	1.3
Leg fat-free mass (right)	2.1	11.1	15.7	4.0	2.9	2.9	3.7	2.9	-3.2	3.8	-2.5	4.0	3.9	-3.8	-1.6
Ever smoked	2.0	3.5	5.5	2.0	2.2	1.3	1.7	1.0	-2.0	2.2	-1.8	2.3	2.3	-1.6	-1.8
Supplements: Calcium	2.0	2.2	4.2	-1.4	-1.4	-2.0	-1.1	-2.1	1.9	-1.4	0.2	-1.5	-1.8	1.5	0.3
Leg fat-free mass (left)	1.9	9.9	13.8	3.6	2.5	2.7	3.5	2.6	-3.1	3.4	-2.8	3.6	3.6	-3.7	-1.8
Leg predicted mass (left)	1.9	9.8	13.7	3.6	2.5	2.7	3.5	2.6	-3.1	3.4	-2.7	3.6	3.6	-3.7	-1.9
Height	1.8	34.6	49.0	6.2	5.4	5.2	5.7	5.1	-7.0	6.2	-5.9	6.6	6.5	-6.6	-3.2
Depression (self-reported)	1.8	2.2	6.6	-1.2	-1.5	-1.4	-1.3	-1.3	2.2	-0.8	2.6	-0.9	-1.2	1.5	0.2
Impedance of arm (left)	1.8	8.1	18.0	-2.9	-1.4	-1.8	-2.0	-1.7	3.0	-3.7	2.4	-3.7	-3.0	4.2	2.7
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.8	6.7	1.6	1.7	1.1	1.4	1.2	-2.6	2.3	-1.5	2.5	1.8	-2.5	-2.3
Ever had bowel cancer screening	1.8	2.1	4.2	1.9	1.0	1.9	1.8	1.9	-0.5	1.5	0.6	1.4	1.0	-0.4	2.1
Illnesses of father: High blood pressure	1.8	2.3	4.3	1.4	2.0	1.0	1.5	1.2	-1.2	1.8	-2.1	1.8	1.5	-1.7	0.2
Pack years of smoking	1.8	2.6	4.6	1.9	1.8	1.8	1.9	1.5	-2.0	1.3	-0.5	1.5	1.6	-2.1	-0.2
Age at First Birth	1.7	2.4	6.7	1.7	0.8	0.8	1.4	0.8	-1.1	1.9	-1.1	2.0	1.8	-2.6	-1.4
Heel T-Score	1.7	13.3	30.7	3.6	3.0	3.5	2.9	3.3	-2.4	5.0	-2.4	5.2	3.4	-5.5	-0.8
Average weekly fortified wine intake	1.7	2.0	3.5	-1.6	-0.9	-1.6	-1.5	-1.8	1.0	-1.6	0.7	-1.6	-1.9	1.4	0.5
Stomach or abdominal pain in last month	1.7	2.1	4.2	1.7	1.5	2.0	1.9	2.1	-0.3	0.7	1.2	0.5	1.5	-0.7	1.9
Hayfever/allergic rhinitis (self-reported)	1.7	2.3	4.7	-1.8	-1.6	-2.2	-2.1	-1.9	0.1	-1.4	0.4	-1.3	-2.1	0.1	0.4
Falls in the last year	1.7	2.3	9.4	-1.0	-0.0	-1.4	-0.9	-1.3	1.2	-1.0	3.1	-1.2	-1.4	2.5	0.6
Fractured/broken bones in last 5 years	1.7	2.2	4.2	-1.7	-2.0	-1.7	-1.8	-1.7	1.0	-1.5	-0.1	-1.5	-1.6	1.5	-0.9
Diabetes (father)	1.6	2.0	4.2	1.9	2.0	1.1	1.8	1.3	-0.3	1.9	-0.3	1.7	1.8	-0.2	-0.6
Hand grip strength (right)	1.6	4.4	7.2	2.7	2.1	2.3	2.2	2.2	-1.6	2.5	-1.5	2.6	2.3	-1.9	-0.3
Past tobacco smoking	1.6	3.0	7.8	-1.7	-2.8	-1.3	-1.6	-1.2	2.1	-1.6	1.3	-1.7	-1.8	1.2	1.7
Mouth/teeth dental problems: Bleeding gums	1.6	2.0	3.9	-1.7	-1.2	-1.2	-1.6	-0.8	1.2	-1.6	0.9	-1.7	-2.0	1.8	0.8
Average weekly champagne plus white wine intake	1.6	2.2	4.2	1.5	1.2	1.0	1.4	0.9	-2.0	1.8	1.1	1.8	1.5	-1.4	-1.6
Relative age of first facial hair	1.5	3.0	6.7	1.9	2.3	2.6	1.6	2.3	-0.4	1.6	0.2	1.8	1.7	-1.8	0.8
Medication: Metformin	1.5	2.1	6.6	1.2	0.2	0.9	1.0	0.9	-1.8	0.8	-2.6	0.9	1.7	-1.7	-1.9
Medication: Atenolol	1.5	1.9	4.1	1.7	1.3	1.0	1.3	0.8	-0.3	2.0	-1.3	2.0	1.8	-1.5	-0.5
Sitting height	1.5	10.5	22.4	2.5	1.8	1.7	2.5	1.7	-4.6	2.9	-4.3	3.4	2.8	-4.7	-3.8
Lung cancer (father)	1.5	1.8	2.9	-1.5	-0.4	-1.5	-1.5	-1.6	1.0	-1.6	0.4	-1.7	-1.7	1.2	-0.9
Shortness of breath walking on level ground	1.5	1.8	4.6	-1.5	-1.0	-0.9	-1.2	-0.9	1.2	-2.1	-0.2	-2.1	-1.1	1.3	1.4
Alcohol intake frequency.	1.5	3.4	6.1	-2.0	-2.1	-1.5	-2.5	-1.6	2.3	-1.8	0.9	-1.9	-2.1	1.9	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.5	1.8	5.9	-1.0	-0.7	0.1	-0.6	-0.2	2.4	-1.7	1.5	-1.7	-1.3	1.1	1.6
Medication: Gliclazide	1.5	1.7	4.8	1.1	0.8	0.9	1.2	0.7	-1.4	0.9	-1.5	1.0	1.4	-2.2	-1.6
Impedance of whole body	1.5	7.8	13.6	-3.3	-1.8	-2.0	-2.7	-2.0	2.5	-3.7	2.3	-3.6	-3.4	3.4	1.7
Hearing difficulty/problems: Yes	1.4	2.2	3.7	1.9	1.4	1.3	1.5	1.3	0.4	1.9	-1.5	1.8	1.8	-1.5	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.9	7.3	1.2	1.3	1.4	0.6	1.4	2.7	0.5	1.6	0.6	0.4	0.8	2.0
Average weekly red wine intake	1.4	2.0	7.8	1.4	2.8	1.5	1.9	1.5	-0.1	0.9	-0.7	1.0	1.5	-1.0	0.7
Handedness (chirality/laterality): Left-handed	1.4	1.7	3.5	-1.7	-0.8	-0.6	-1.0	-1.1	1.1	-1.9	-0.0	-1.8	-1.5	1.2	1.5
Back pain experienced in last month	1.4	2.0	3.3	1.7	1.2	1.8	1.7	1.8	-0.8	1.2	-1.1	1.2	1.8	-1.5	0.1
Schizophrenia vs Biploar Disorder	1.3	1.7	3.5	-1.9	-0.8	-1.5	-1.3	-1.5	0.4	-1.6	0.8	-1.6	-1.7	0.9	0.1
Bipolar Disorder (2011)	1.3	1.3	3.1	1.1	1.0	0.8	0.9	1.0	-1.0	1.8	-0.5	1.7	1.4	-1.2	-0.3
Alzheimer’s Disease (including proxy)	1.2	1.8	3.7	-1.6	-0.5	-1.3	-1.2	-1.4	0.9	-1.8	1.0	-1.9	-1.7	1.0	0.8
Major Depression (MDD)	1.2	1.4	3.6	1.1	1.9	1.6	1.7	1.5	0.8	-0.3	1.4	0.0	1.3	-0.4	0.5
Triglycerides	1.2	2.0	3.5	1.7	0.5	1.6	1.4	1.7	-0.4	1.2	-1.4	1.3	1.9	-1.8	-1.2
Type 2 Diabetes (T2D) (2018)	1.2	2.2	9.7	0.8	0.7	-0.1	0.7	0.0	-2.4	1.0	-3.1	1.0	1.0	-1.5	-2.1
Vitamin and mineral supplements	1.2	1.6	4.7	1.0	2.2	1.5	1.1	1.6	-0.7	1.0	-1.2	1.0	1.0	-1.4	0.2
Severe depression (siblings)	1.2	1.3	2.7	1.5	0.9	1.4	1.6	1.4	0.9	0.2	1.2	0.2	1.3	0.8	1.2
Impedance of leg (right)	1.2	5.9	10.8	-3.1	-2.0	-2.0	-2.8	-2.0	1.8	-3.3	1.5	-3.2	-3.1	2.5	0.3
Townsend deprivation index at recruitment	1.2	1.7	3.5	1.2	1.7	1.3	1.2	1.2	-1.9	1.3	-0.5	1.3	1.2	-1.7	-0.0
Multivitamins +/- minerals	1.2	1.5	4.5	-1.2	-2.1	-1.2	-1.2	-1.4	0.7	-1.1	1.5	-1.1	-1.3	0.7	-0.5
Qualifications: None of the above	1.2	2.6	4.0	-1.8	-1.4	-1.7	-2.0	-1.7	1.6	-1.9	1.1	-1.9	-1.5	1.7	-0.9
Alcohol intake versus 10 years previously	1.2	1.8	4.0	-1.2	-0.6	-0.6	-0.9	-0.8	1.7	-1.9	1.1	-1.9	-1.3	2.0	1.1
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.3	2.8	1.3	1.5	1.6	0.9	1.7	0.2	1.3	0.2	1.3	1.3	-0.9	0.4
Family relationship satisfaction	1.2	1.5	6.1	1.0	1.6	0.7	1.2	0.5	0.5	0.3	2.0	0.1	0.3	1.5	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	6.0	1.0	1.2	1.3	1.3	1.1	0.7	0.4	1.7	0.5	0.4	-0.4	2.5
Depression (Nagel 2018)	1.1	1.6	3.2	1.8	1.4	1.7	1.1	1.7	1.2	0.9	1.2	1.0	1.0	-0.6	0.8
Reaction Time	1.1	2.0	5.2	1.4	1.7	2.1	1.6	2.3	0.1	0.7	-0.7	0.5	1.2	0.5	2.1
LDL Cholesterol	1.1	1.8	4.8	-1.4	-1.5	-1.0	-1.3	-1.1	0.8	-2.0	0.9	-2.2	-1.4	0.9	-0.1
Smoking Status	1.1	2.6	4.5	1.6	2.1	1.6	1.2	1.8	-1.7	1.7	-0.9	1.9	1.7	-1.3	-1.3
Medication: Omeprazole	1.1	1.3	4.4	1.3	1.5	1.0	1.5	0.9	2.1	0.5	1.1	0.5	0.9	0.4	0.8
Smoking status: Previous	1.1	1.7	5.5	1.1	2.3	0.9	1.0	0.8	-1.6	0.9	-1.3	1.0	1.2	-0.8	-1.7
Medication for cholesterol	1.1	1.7	3.3	-1.1	-1.0	-1.3	-0.9	-1.3	1.1	-1.5	1.7	-1.6	-1.0	1.8	-0.9
Guilty feelings	1.1	1.7	3.3	1.6	1.3	1.5	1.3	1.8	0.6	1.5	0.7	1.6	1.1	-1.3	0.5
Medication: Paracetamol	1.1	1.7	7.2	1.4	2.7	1.4	1.7	1.3	-0.6	0.7	-0.5	0.9	1.5	-0.9	0.6
Ever depressed for a whole week	1.1	1.4	4.7	1.3	2.2	1.0	1.7	0.8	-0.8	1.1	1.2	1.0	1.0	-0.3	0.3
Myopia	1.1	1.6	5.0	-0.8	-1.3	-0.5	-0.7	-0.7	2.2	-0.6	2.1	-0.8	-1.1	1.0	1.6
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.5	0.9	1.4	1.1	1.0	0.9	-1.0	1.0	-1.2	1.2	1.0	-1.6	1.6
Intelligence (Savage-Jansen 2018)	1.0	3.1	7.1	2.3	1.0	1.9	2.5	1.9	-0.5	2.0	-1.0	1.7	2.7	-1.0	-1.0
Lupus	1.0	1.4	3.0	1.7	0.7	1.5	1.4	1.5	-0.2	1.7	-0.2	1.5	1.4	-0.3	0.4
Pack years adult smoking proportion	1.0	1.5	2.6	1.4	1.4	1.5	1.5	1.2	-1.6	0.8	-0.3	1.1	1.3	-1.6	-0.0
Qualifications: CSEs or equivalent	1.0	1.3	3.5	0.6	0.9	1.7	0.9	1.9	-1.3	0.4	-0.9	0.7	0.4	-1.1	1.6
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	4.4	1.4	2.1	0.8	1.7	0.7	0.3	0.7	1.1	0.5	1.0	0.0	0.9
Heart attack	1.0	1.3	2.2	0.9	1.4	1.0	0.9	0.8	-1.1	1.0	-1.4	1.2	1.0	-1.5	1.3
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.9	1.0	2.0	1.0	1.1	0.9	1.5	1.0	1.2	1.0	0.6	-0.7	0.7
Medication: Paracetamol	1.0	1.7	4.8	1.4	2.2	1.5	1.6	1.4	-0.5	1.1	-0.3	1.2	1.5	-1.2	0.1
Exposure to tobacco smoke outside home	1.0	1.3	4.4	0.9	1.1	0.5	0.7	0.7	-0.4	1.2	-2.1	1.1	0.8	-1.4	-1.5
Medication: Ibuprofen	1.0	1.2	2.6	0.8	0.4	1.2	0.5	1.0	-1.4	1.4	-1.6	1.3	0.9	-1.5	-0.0
Mean time to correctly identify matches	1.0	1.9	3.6	1.8	1.8	1.8	1.7	1.9	-0.7	1.3	-0.5	1.1	1.7	-0.1	1.0
Mother’s age at death	1.0	1.2	2.2	1.4	1.0	0.8	1.3	0.8	-0.9	1.1	-1.0	1.3	1.5	-1.3	-0.5
Tinnitus: Yes, now most or all of the time	1.0	1.2	4.5	0.7	1.2	1.5	0.8	1.4	0.1	-0.0	1.4	-0.1	0.6	0.8	2.1
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	3.6	1.2	1.3	1.0	1.4	0.7	1.9	0.3	1.4	0.3	0.8	0.5	1.0
Verbal and Numeric Reasoning (VNR)	0.9	2.1	4.7	1.8	1.4	1.5	2.2	1.5	-0.7	1.2	0.0	1.2	1.9	-1.4	-1.2
Taking other prescription medications	0.9	1.3	3.2	-0.8	-0.4	-1.2	-0.4	-1.3	1.8	-1.7	0.7	-1.6	-0.7	1.3	0.7
Medication: Levothyroxine sodium	0.9	1.4	3.5	-1.6	-1.3	-0.9	-1.8	-1.4	-0.7	-1.4	0.3	-1.1	-1.9	0.5	-0.3
Impedance of leg (left)	0.9	4.2	6.8	-2.6	-1.7	-1.5	-2.4	-1.6	1.5	-2.6	1.9	-2.5	-2.6	2.1	0.5
Arm fat percentage (right)	0.9	3.6	6.1	-1.9	-2.0	-1.7	-1.8	-1.7	1.9	-2.5	1.6	-2.5	-2.0	1.9	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	5.4	0.1	-0.7	0.4	-0.2	0.3	2.2	-0.0	1.8	-0.2	-0.1	1.6	2.3
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	3.6	0.7	0.1	1.4	0.4	1.0	-1.6	1.2	-1.2	1.2	0.6	-1.9	0.1
Prospective memory result	0.9	1.1	3.5	-0.8	-1.1	-1.4	-0.8	-1.5	0.5	-0.8	0.4	-1.1	-0.6	1.9	0.2
Exposure to tobacco smoke at home	0.9	1.1	2.5	-1.2	-1.2	-0.9	-0.7	-1.0	-0.2	-1.6	0.3	-1.4	-1.3	-0.1	-1.1
Leg fat percentage (right)	0.9	3.3	5.8	-2.0	-2.4	-2.0	-2.0	-2.0	1.1	-2.3	1.0	-2.2	-2.0	1.3	-0.4
Qualifications: College or University degree	0.9	2.9	4.7	1.7	0.5	1.7	2.0	1.6	-1.9	2.0	-1.4	1.9	2.2	-1.8	-0.9
Diabetes diagnosed by doctor	0.9	1.5	5.9	0.8	0.6	0.5	0.6	0.5	-2.2	0.9	-2.4	0.9	1.2	-1.1	-1.4
Basal cell carcinoma (self-reported)	0.9	1.1	3.2	1.3	1.8	0.4	1.5	0.3	-1.0	0.9	-0.5	0.8	1.5	-0.7	-0.7
Alcohol drinker status: Previous	0.9	1.0	2.2	-1.2	-0.3	-0.5	-1.4	-0.6	1.1	-1.2	0.6	-1.3	-1.5	1.0	0.5
Rheumatoid Arthritis	0.8	1.1	3.6	-0.9	-0.9	-0.4	-0.5	-0.3	0.9	-1.0	1.9	-1.1	-0.9	1.5	1.2
Chronic bronchitis/emphysema (father)	0.8	0.9	2.7	-0.6	-0.0	-0.8	-0.6	-0.7	1.4	-0.7	1.4	-0.9	-0.9	1.7	0.2
Fluid intelligence score	0.8	1.6	5.3	1.2	0.2	0.9	1.2	1.0	-0.4	0.9	-0.3	1.0	1.5	-2.3	-2.3
Weight	0.8	3.9	7.4	2.2	0.9	1.5	1.9	1.4	-2.2	2.1	-1.9	2.3	2.2	-2.7	-1.7
Father’s age at death	0.8	1.1	3.2	-0.8	-1.8	-1.2	-1.4	-1.1	-1.2	0.2	-1.3	0.1	-0.3	-0.4	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.1	4.9	0.3	1.6	0.4	0.6	0.3	2.2	-0.1	0.4	-0.3	-0.0	1.4	1.5
Chest pain or discomfort	0.8	1.1	2.6	1.2	1.3	1.4	1.6	1.5	0.2	-0.1	1.0	-0.1	0.9	0.4	1.0
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	3.1	0.1	-0.3	-0.8	0.2	-1.0	-1.2	0.8	-1.6	0.8	0.5	-1.2	-1.8
Illnesses of father: None of the above (group 1)	0.8	1.0	1.7	-1.1	-1.2	-0.8	-1.3	-0.7	-0.7	-1.0	0.8	-0.9	-1.2	0.4	-1.2
Average weekly beer plus cider intake	0.8	1.2	4.5	-0.7	0.2	-0.2	-0.3	-0.2	1.4	-1.2	2.1	-1.3	-0.9	1.7	0.2
Alzheimer’s Disease (in mother)	0.7	0.8	1.9	-1.1	-1.4	-1.1	-0.9	-1.2	-0.8	-0.7	0.5	-0.7	-0.8	0.3	-0.8
Ulcerative Colitis	0.7	1.1	5.5	-1.2	-1.1	-0.6	-0.9	-0.8	-1.0	-1.0	2.3	-0.8	-0.6	-0.3	-0.0
Allergy or Eczema	0.7	1.7	5.8	-1.2	-2.4	-0.9	-1.5	-0.7	0.9	-0.9	1.8	-1.0	-1.3	0.8	1.3
Cardiovascular Disease	0.7	2.4	10.0	1.6	1.0	1.0	0.8	1.1	-1.2	1.7	-3.2	1.6	1.9	-1.2	-0.9
Medication for hormone replacement therapy	0.7	0.7	2.2	0.9	0.6	1.5	0.8	1.4	0.0	0.9	-0.3	0.8	0.4	0.4	1.0
Supplements: Glucosamine	0.7	1.0	2.3	1.1	0.6	0.8	0.6	0.9	-0.7	1.5	-0.0	1.4	1.5	-1.1	0.5
Diabetes (self-reported)	0.7	1.1	5.2	0.2	0.2	-0.2	-0.2	-0.2	-2.1	0.6	-2.3	0.5	0.5	-0.8	-1.5
Medication: Simvastatin	0.7	1.0	2.3	1.2	0.7	1.1	0.5	0.8	-1.5	1.3	-0.6	1.2	1.3	-0.4	-0.6
Hair/balding pattern: Pattern 4	0.7	1.7	5.2	-1.5	-1.0	-0.9	-1.2	-0.8	1.0	-2.3	0.0	-2.0	-1.6	0.5	0.7
Medication: Seretide 50 evohaler	0.7	0.8	3.4	0.4	0.8	0.8	0.5	0.6	-1.8	0.2	0.3	0.7	0.3	-1.9	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	1.8	1.2	0.2	0.8	1.1	0.9	-0.5	1.3	-0.0	1.2	1.3	-1.0	-0.2
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.8	-1.2	-0.9	-1.3	-1.0	-1.2	0.1	-0.8	-0.6	-0.9	-1.1	0.5	0.4
Eye problems/disorders: Glaucoma	0.7	0.8	2.4	-0.6	0.8	-1.1	-0.4	-1.1	1.0	-0.5	-1.6	-0.3	-0.4	-0.4	-1.2
Leg fat percentage (left)	0.7	2.4	4.9	-1.6	-2.2	-1.7	-1.8	-1.8	0.9	-1.8	1.3	-1.7	-1.6	0.9	-0.4
Cholesterol lowering medication	0.7	1.0	3.4	0.9	0.3	0.8	1.0	0.7	-1.6	0.3	-1.9	0.4	1.3	-0.8	-0.2
Depressed Affect (Nagel 2018)	0.6	1.2	2.6	1.2	1.2	1.1	1.1	1.2	1.5	0.8	1.6	0.7	1.0	-0.1	0.9
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.1	1.1	0.0	0.3	0.5	0.3	-1.5	0.9	-0.4	1.0	1.0	-0.7	-1.0
Blood White Count	0.6	4.7	14.1	-0.2	-0.6	0.4	1.1	0.4	3.1	-2.4	2.2	-2.6	-0.4	3.6	3.8
Hypothyroidism (self reported)	0.6	1.4	3.9	-1.4	-0.3	-0.0	-0.9	-0.4	0.7	-2.0	1.1	-1.8	-1.5	1.6	0.9
Age when periods started (menarche)	0.6	1.4	5.9	0.0	0.1	-0.6	-0.8	-0.4	-2.4	1.0	-1.1	1.2	-0.0	-1.5	-2.0
Hayfever, allergic rhinitis or eczema	0.6	1.2	3.0	-1.2	-1.7	-0.7	-1.1	-0.6	0.4	-1.1	1.1	-1.1	-1.3	0.4	1.6
Alcohol usually taken with meals	0.6	0.9	2.8	0.9	-0.1	-0.3	0.9	-0.1	0.1	1.3	-1.7	1.2	1.2	0.1	-1.3
Mouth/teeth dental problems	0.6	0.9	1.7	1.2	0.5	0.9	1.2	0.7	-1.2	1.3	-0.8	1.0	1.3	0.5	0.0
Tense / ‘highly strung’	0.6	1.0	4.7	0.2	-0.8	0.1	0.2	0.2	2.2	-0.2	0.9	-0.5	-0.2	1.6	1.9
Pulse wave reflection index	0.6	0.7	2.2	-0.7	-1.5	-0.5	-0.5	-0.8	-0.1	-1.3	-0.1	-1.2	-0.5	-0.4	-1.2
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	2.2	-1.3	-0.8	-0.4	-1.3	-0.8	0.2	-1.5	0.9	-1.4	-1.4	1.3	0.3
Body fat percentage	0.6	2.6	4.7	-1.7	-1.8	-1.4	-1.6	-1.4	1.3	-2.2	1.5	-2.1	-1.8	1.4	0.3
Number of children fathered	0.6	0.7	3.9	-0.1	-0.4	-0.6	-0.5	-0.4	-0.9	-0.2	-1.1	-0.0	0.2	-1.1	-2.0
Health satisfaction	0.6	0.8	3.7	-0.5	0.2	-0.4	-0.2	-0.6	0.5	-1.1	0.8	-1.1	-0.4	1.0	1.9
Overall health rating	0.6	1.3	2.9	-0.6	-0.2	-0.9	-0.8	-0.9	1.3	-0.9	1.7	-1.0	-1.1	1.6	1.6
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.8	2.4	-0.2	-1.2	-0.6	-1.1	-0.5	-0.7	0.6	-0.4	0.8	-0.5	-1.2	-1.6
Hypertension (Self-reported)	0.6	1.8	5.9	1.5	1.4	0.9	0.8	0.9	-0.7	1.5	-2.4	1.4	1.5	-0.8	-1.2
Arm fat percentage (left)	0.6	2.4	4.4	-1.5	-1.7	-1.2	-1.4	-1.2	1.5	-2.1	1.5	-2.1	-1.6	1.7	0.7
Eye problems/disorders: Cataract	0.6	0.7	2.6	-0.4	-1.3	-1.0	-0.8	-1.0	-0.7	0.2	-0.6	0.4	0.0	-0.5	-1.6
Miserableness	0.6	1.0	2.1	1.1	0.7	1.1	1.2	1.0	0.6	1.3	0.2	1.4	0.9	-1.3	0.0
Ever taken oral contraceptive pill	0.6	0.6	1.6	0.9	0.6	1.0	0.4	1.0	-0.3	1.3	-0.1	1.0	0.8	-0.4	0.8
Pain type(s) experienced in last month: Hip pain	0.6	0.7	1.7	1.3	0.7	0.7	1.3	0.8	0.4	1.0	-0.3	0.7	1.3	0.2	-0.8
Medication: Atorvastatin	0.6	0.7	2.6	-0.7	-0.3	-1.3	-0.2	-1.3	-0.5	-0.8	-1.6	-0.8	-0.8	0.1	0.1
Waist Hip Ratio (WHR)	0.5	2.1	10.0	0.8	0.8	0.6	0.0	1.0	-3.2	1.3	-1.8	1.3	0.8	-1.6	-1.7
Average weekly spirits intake	0.5	0.6	2.0	-0.1	-1.4	1.2	-0.6	1.0	-0.6	-0.2	0.4	-0.1	-0.0	-0.4	1.3
Trunk fat percentage	0.5	2.0	4.3	-1.4	-1.4	-1.0	-1.2	-1.1	1.3	-2.1	1.4	-2.0	-1.5	1.5	0.5
Maternal smoking around birth	0.5	0.7	2.3	0.9	1.5	1.1	0.9	1.5	-0.4	-0.0	-0.4	0.0	0.6	-0.0	0.1
High blood pressure	0.5	1.3	5.4	1.2	0.9	0.7	0.5	0.8	-0.4	1.2	-2.3	1.2	1.2	-0.8	-1.1
Nervous feelings	0.5	1.0	2.6	-0.9	-1.6	-1.5	-1.4	-1.5	0.9	-0.5	-0.4	-0.4	-0.9	-0.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.7	0.9	0.7	0.5	0.6	0.6	0.9	1.3	1.6	1.2	0.5	0.7	0.3
Allergy	0.5	1.1	4.1	1.0	1.1	0.7	0.8	0.6	-0.6	1.0	-1.4	0.9	1.2	-0.3	-2.0
Medication: Cholesterol lowering	0.5	0.7	3.2	0.7	1.8	0.0	0.4	0.0	-1.3	0.9	-1.3	0.7	0.5	-0.0	-0.1
Blood clot in the leg (DVT)	0.5	0.7	2.4	-1.1	-0.9	-1.6	-0.7	-1.3	-0.3	-0.5	0.3	-0.5	-0.9	0.5	0.3
Glaucoma (self-reported)	0.5	0.5	2.5	0.3	1.2	-0.3	0.1	-0.4	0.1	0.5	-1.6	0.6	0.4	-0.8	-0.9
Worry too long after embarrassment	0.5	0.9	1.7	1.2	-0.5	0.8	0.9	0.8	-1.2	1.3	-0.2	1.3	1.0	-1.2	0.0
Eye problems/disorders: None of the above	0.5	0.5	3.1	0.1	-0.4	1.1	0.2	1.1	0.4	-0.3	0.4	-0.3	-0.2	-0.2	1.8
Mouth/teeth dental problems: Loose teeth	0.5	0.6	3.1	-0.9	-0.7	-0.2	-0.9	-0.2	0.2	-0.7	-1.8	-0.5	-0.8	0.1	-0.4
Neck or shoulder pain in last month	0.5	0.6	2.7	0.1	-0.3	1.0	0.1	0.9	1.0	-0.6	1.6	-0.6	-0.1	0.3	1.2
Angina (self-reported)	0.5	0.6	1.7	-0.5	0.0	-0.9	-0.5	-1.2	1.0	-0.5	1.1	-0.5	-1.3	0.3	0.5
Number of full sisters	0.5	0.6	3.8	0.0	0.3	0.9	0.3	0.7	1.9	-0.5	-0.4	-0.5	0.0	0.4	1.2
Loneliness, isolation	0.5	0.7	3.4	-0.5	0.1	-0.7	-0.4	-0.8	1.6	0.1	1.8	0.1	-0.9	0.3	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.8	-1.3	-1.0	-0.7	-0.9	-0.6	1.0	-1.3	0.3	-1.1	-1.0	-0.4	0.3
Hearing aid user	0.5	0.6	3.0	0.7	0.2	0.2	0.7	-0.0	0.0	0.4	-1.3	0.4	0.7	0.2	-1.7
High cholesterol (Self-reported)	0.5	1.0	6.1	0.0	0.5	-0.5	-0.0	-0.8	-1.8	0.1	-2.5	-0.0	0.3	-0.0	-1.0
Medication: Lisinopril	0.5	0.6	1.3	0.8	1.0	0.8	1.2	1.0	-0.5	0.7	-0.8	0.7	0.8	-0.4	0.4
Bipolar Disorder (2018)	0.4	0.7	2.0	1.1	0.4	0.8	1.1	0.8	-0.5	0.9	0.1	1.1	1.4	-0.5	0.1
Neuroticism	0.4	0.9	3.0	1.0	0.4	0.8	0.7	1.0	1.7	1.1	0.9	1.1	0.7	-0.8	0.8
Sensitivity / hurt feelings	0.4	0.6	3.4	0.4	-0.1	0.5	0.5	0.6	1.2	-0.3	1.9	-0.5	0.1	1.1	0.7
Frequency of depressed mood in last 2 weeks	0.4	0.5	3.2	0.4	-0.2	0.6	-0.0	0.7	1.4	0.0	1.8	0.2	-0.0	-0.4	0.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	2.2	-0.2	0.8	-0.1	-0.0	-0.0	1.2	-0.9	-0.4	-0.9	-0.4	0.8	1.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.6	-0.2	0.2	-0.6	-0.2	-0.7	0.4	0.0	-1.2	0.3	0.3	-0.8	-1.3
Angina	0.4	0.5	1.5	-0.3	0.2	-0.9	-0.4	-1.2	0.8	-0.3	1.2	-0.3	-1.1	0.1	0.3
Supplements: Zinc	0.4	0.4	3.3	-0.1	0.5	0.3	0.2	0.7	0.0	0.1	-0.4	0.3	0.1	-0.5	1.8
Fed-up feelings	0.4	0.7	2.4	0.6	1.1	0.5	0.6	0.6	1.3	0.8	1.5	0.6	0.1	0.0	1.1
Serious illness, injury or assault to yourself	0.4	0.5	1.0	1.0	0.1	0.8	0.8	0.9	0.2	0.8	-0.6	0.8	0.9	-0.4	0.1
Waist circumference	0.4	1.3	3.7	1.1	0.2	0.5	0.7	0.6	-1.9	0.9	-1.5	1.0	1.1	-1.4	-1.5
Number of incorrect matches in round	0.4	0.7	4.8	-0.2	-0.4	-0.2	-0.3	-0.1	2.2	-0.5	-0.7	-0.7	-0.2	1.0	1.1
Hair/balding pattern: Pattern 2	0.4	0.5	1.4	-1.2	-0.0	-0.8	-0.8	-0.8	-0.2	-1.0	-0.4	-0.7	-1.1	-0.1	-0.4
Neuroticism score	0.4	0.9	2.9	1.0	0.1	0.9	0.7	1.1	1.7	1.0	1.2	1.0	0.4	-0.6	0.8
Forced expiratory volume in 1-second (FEV1)	0.4	1.5	3.2	-1.5	0.2	-0.6	-0.7	-0.7	1.8	-1.6	1.5	-1.1	-1.8	0.6	1.2
Noisy workplace	0.4	0.5	2.8	0.6	0.6	0.1	0.0	-0.1	0.0	0.9	-0.6	0.9	0.6	-0.7	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	3.5	-1.6	-0.7	-0.6	-1.0	-0.8	0.8	-1.5	1.6	-0.9	-1.9	-0.1	1.2
Breastfed as a baby	0.4	0.5	2.5	-0.6	-1.6	-0.5	-0.4	-0.6	-0.3	-0.8	0.8	-0.7	-0.4	-0.3	-0.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.6	0.7	1.6	0.4	0.6	0.2	-0.6	1.3	0.1	1.2	0.2	-0.4	0.5
Medication: Amlodipine	0.4	0.5	2.5	0.1	0.4	0.1	0.1	-0.1	-1.2	-0.1	-1.6	0.0	-0.0	-0.9	1.0
Number of full brothers	0.4	0.5	2.2	-0.3	-0.6	-0.1	-0.6	0.2	-0.3	-1.0	0.5	-1.0	-0.5	0.3	-1.5
Medication: Allopurinol	0.4	0.5	2.7	0.1	0.0	-0.4	-0.2	-0.4	-0.9	0.8	-0.6	1.1	-0.3	-1.7	-0.1
Heart disease (mother)	0.4	0.4	2.1	0.6	1.5	0.9	0.6	0.7	-0.3	0.2	-0.2	0.4	0.7	-0.3	0.3
Comparative height size at age 10	0.4	2.3	8.7	1.5	1.1	0.9	1.7	0.8	-1.6	1.0	-1.5	1.1	1.6	-1.5	-3.0
Medication: Aspirin	0.4	0.5	1.2	1.1	0.6	0.7	1.0	0.7	-1.0	0.4	-0.6	0.4	0.8	-0.3	-0.7
Mood swings	0.4	0.8	2.8	0.2	0.2	0.7	0.1	0.7	1.5	0.0	1.7	-0.2	-0.0	0.7	1.6
Qualifications: nursing, teaching	0.4	0.7	2.8	-0.1	-1.7	-0.7	-0.2	-0.6	0.4	-0.0	-1.1	0.0	0.1	-0.6	-1.6
Medication: Aspirin	0.4	0.5	1.0	1.0	0.4	0.5	0.8	0.5	-0.8	0.7	-0.8	0.7	0.8	-0.4	-0.9
Wears glasses or contact lenses	0.4	0.4	1.4	0.4	-0.0	0.0	-0.3	0.0	-1.0	1.1	-0.1	1.0	0.3	-1.2	-0.1
Ever had prostate specific antigen (PSA) test	0.4	0.5	3.8	0.3	0.4	-0.1	-0.1	0.3	-0.2	0.0	1.9	-0.2	-0.1	0.8	0.8
Unable to work because of sickness or disability	0.4	0.5	1.8	-0.4	0.4	-0.8	-0.2	-0.7	1.3	-0.4	0.7	-0.6	-0.1	1.2	0.3
Commuting to job workplace: Cycle	0.4	0.5	2.0	0.5	0.0	-0.2	0.2	-0.1	-0.6	0.9	-1.4	1.0	0.7	0.0	-1.0
Vascular/heart problems diagnosed by doctor	0.4	1.1	6.6	-0.9	-1.0	-0.3	-0.2	-0.3	0.3	-1.0	2.6	-1.0	-0.8	0.9	1.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.5	-0.8	-0.8	-1.2	-0.4	-1.0	-0.5	-0.3	0.3	-0.4	-0.7	0.6	0.5
Heart disease (siblings)	0.4	0.5	1.1	1.0	0.9	1.0	0.9	1.0	-0.5	-0.1	-0.1	-0.1	0.7	0.5	-0.3
Neuroticism (Nagel 2018)	0.3	0.8	2.1	1.1	0.3	0.6	0.7	0.9	1.4	1.3	0.5	1.1	0.9	-0.4	0.6
Worry (Nagel 2018)	0.3	0.6	3.9	-0.1	-1.2	-0.5	-0.7	-0.3	2.0	0.7	-0.3	0.7	-0.3	-0.2	0.5
Ulcerative Colitis (UC)	0.3	0.6	2.6	-0.5	-0.8	-0.5	-0.3	-0.5	-1.6	-0.4	1.3	-0.1	-0.2	-1.1	-0.4
Coronary Artery Disease (CAD)	0.3	0.3	1.0	-0.4	0.4	-0.9	-0.2	-1.0	-0.2	-0.7	0.0	-0.2	-0.3	-0.2	-1.0
Fasting Glucose	0.3	0.3	0.8	0.7	0.1	0.5	0.5	0.4	0.2	0.6	-0.9	0.8	0.7	-0.6	0.2
Lung FEV1/FVC ratio	0.3	1.4	3.0	-1.3	-1.4	-1.4	-1.5	-1.3	-1.7	-0.9	-1.0	-0.8	-0.9	0.0	-0.9
Chronotype (morning person)	0.3	0.6	2.3	0.5	1.5	0.8	0.7	0.7	-0.7	0.6	-0.3	0.6	0.9	-0.9	0.1
Number of treatments/medications taken	0.3	0.5	1.5	0.4	0.1	0.5	0.4	0.4	1.0	-0.3	-1.2	-0.2	0.6	0.7	1.2
Ever had hysterectomy (womb removed)	0.3	0.4	0.6	0.7	-0.5	0.7	0.3	0.8	0.1	0.5	0.7	0.3	0.7	0.5	0.8
Medication: Co-codamol	0.3	0.3	0.8	0.0	0.6	-0.9	-0.3	-0.8	0.7	-0.4	-0.1	-0.4	-0.0	0.8	-0.7
Hearing difficulty/problems with background noise	0.3	0.4	1.3	0.7	0.4	0.9	0.6	0.9	1.1	0.2	-0.6	0.3	0.5	-0.7	-0.1
Forced vital capacity (FVC)	0.3	1.3	4.4	-1.0	0.5	-0.0	-0.1	-0.1	2.1	-1.2	1.8	-0.8	-1.3	0.5	1.4
Medication: Ramipril	0.3	0.4	1.1	-0.4	0.7	-0.7	-0.0	-0.8	0.2	-0.6	0.1	-0.8	0.0	1.1	-1.0
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.0	0.4	0.7	0.0	0.3	-0.1	0.1	1.4	-0.3	1.3	0.3	-1.1	-1.4
Illnesses of mother	0.3	0.4	1.8	-0.6	-1.4	-1.0	-0.3	-1.0	0.8	-0.1	-0.6	-0.0	0.0	0.2	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.1	-0.7	-0.3	-1.1	-0.9	-1.0	0.9	-0.2	0.8	-0.1	-0.7	0.1	-0.5
Loud music exposure frequency	0.3	0.3	1.4	-0.5	0.2	-0.2	-0.5	-0.3	-0.7	-0.1	-0.7	0.1	-0.8	-1.2	0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.0	-0.5	-1.4	-0.2	-0.4	-0.3	0.3	-0.0	1.3	0.1	-0.4	-1.1	-0.1
Gout (self-reported)	0.3	0.4	1.6	0.2	0.4	-0.2	-0.3	-0.1	-1.1	0.5	-0.9	0.7	-0.4	-1.3	-0.1
Chronic bronchitis/emphysema (mother)	0.3	0.3	0.8	0.6	-0.0	0.9	0.7	0.9	-0.5	-0.1	-0.8	0.0	0.6	-0.2	0.6
High blood pressure (siblings)	0.3	0.5	2.5	-0.2	-0.5	-0.4	-0.4	-0.4	-0.4	-0.3	-1.6	-0.2	-0.1	-0.8	-1.2
Forced vital capacity (FVC), Best measure	0.3	1.1	3.7	-1.2	-0.4	0.1	-0.5	-0.2	1.1	-1.3	1.9	-0.7	-1.5	-0.3	1.4
Comparative body size at age 10	0.3	0.8	6.8	-0.2	-0.3	-0.4	0.3	-0.6	2.6	-0.5	0.1	-0.6	-0.1	1.2	0.0
Age at first live birth	0.3	0.6	1.4	0.7	1.1	1.1	0.9	0.9	0.2	0.4	0.5	0.3	0.3	-0.3	1.2
Had major operations	0.3	0.3	1.0	0.6	0.7	0.5	0.9	0.4	1.0	0.3	-0.2	0.2	0.5	-0.0	0.4
Leg pain on walking	0.3	0.3	0.9	0.7	0.2	0.5	0.9	0.3	0.9	0.2	0.6	0.3	0.6	0.1	0.7
Knee pain experienced in last month	0.3	0.5	2.3	0.8	0.4	0.2	0.6	0.2	-0.5	0.9	0.9	0.7	0.5	-0.5	-1.5
Long-standing illness, disability or infirmity	0.3	0.4	1.9	0.2	0.2	0.5	0.5	0.4	0.5	-0.9	-0.7	-0.7	-0.1	0.3	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	3.1	-0.0	0.1	-0.1	-0.2	-0.1	0.6	0.1	1.8	-0.1	0.0	0.5	0.2
Friendships satisfaction	0.3	0.3	1.1	0.1	0.7	-0.4	0.3	-0.3	0.8	0.1	1.0	0.1	-0.3	0.9	0.6
Commuting to job workplace: Walk	0.3	0.3	1.2	0.5	1.1	0.3	-0.0	0.3	0.6	0.7	-0.1	0.6	0.4	0.4	0.4
Mineral and other dietary supplements	0.3	0.4	1.1	-0.7	-0.3	-0.2	-0.4	-0.5	0.3	-1.0	-0.4	-1.0	-0.8	0.5	-0.9
Osteoarthritis (self-reported)	0.3	0.3	1.4	-0.1	0.0	0.2	-0.4	0.4	0.5	-0.6	-0.7	-0.7	-0.1	0.8	1.2
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.3	0.4	0.3	0.3	-0.1	0.6	-0.4	0.8	1.5	0.8	0.4	-0.3	0.5
Diastolic blood pressure, automated reading	0.3	0.9	2.3	-1.3	-0.5	-1.1	-1.5	-1.1	0.0	-0.7	-1.5	-0.5	-1.0	-0.1	-0.3
Bipolar Disorder or Schizophrenia	0.2	0.5	1.5	0.4	-0.1	0.3	0.6	0.3	-0.9	0.9	-0.1	1.2	1.0	-1.2	-0.4
Irritable Bowel Disease (IBD)	0.2	0.4	2.7	-0.5	0.2	-0.6	-0.2	-0.6	-1.6	-0.2	0.9	-0.1	-0.1	-0.8	-0.2
Breast Cancer	0.2	0.4	2.4	0.1	-0.4	0.3	0.0	0.5	-1.5	0.0	-1.1	0.3	0.4	-1.0	-0.3
Body Mass Index (BMI) (2010)	0.2	0.3	0.8	-0.0	-0.6	-0.1	-0.7	-0.1	0.9	0.6	0.3	0.5	-0.0	0.8	-0.9
Crohns Disease (2012)	0.2	0.4	1.2	0.2	1.1	0.3	0.4	0.3	0.1	0.6	-0.8	0.4	0.2	0.8	1.0
Mean Putamen Volume	0.2	0.2	1.0	-0.3	-0.6	-0.1	-0.4	-0.1	-0.3	0.2	1.0	-0.1	0.0	0.8	-0.1
Neuroticism (2016)	0.2	0.2	1.1	0.3	0.2	0.0	0.0	0.0	-0.8	0.1	0.3	0.2	0.3	-1.0	-0.8
Schizophrenia (2014)	0.2	0.4	1.4	0.1	-0.1	0.6	0.3	0.4	-0.7	0.6	0.2	1.0	0.8	-1.2	-0.3
Respiratory disease	0.2	0.5	1.8	0.5	0.9	0.9	0.8	0.9	0.4	0.3	0.4	0.4	0.5	-0.7	1.4
Hair Pigment	0.2	5.8	14.6	2.0	3.1	1.0	1.5	0.9	-2.6	3.2	-3.8	3.1	2.1	-2.3	-0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.5	-0.1	-0.2	-0.4	-0.2	-0.5	0.4	-0.5	0.8	-0.6	-0.5	1.2	0.3
Systolic blood pressure, automated reading	0.2	0.6	1.3	-0.5	-0.9	-1.1	-1.2	-1.1	0.3	-0.3	-0.6	-0.2	-0.3	0.3	-1.2
Relative age voice broke	0.2	0.3	1.3	0.1	0.1	1.0	-0.3	1.1	1.1	0.2	0.0	0.4	0.0	-0.3	0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.7	-0.2	-0.5	0.0	-0.4	0.1	0.6	-0.2	-0.8	-0.2	-0.4	-0.2	0.8
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.1	-0.5	0.1	0.1	-0.5	-0.0	-1.1	-0.4	-0.7	-0.2	-0.6	0.2	0.6
Had other major operations	0.2	0.2	1.2	-0.5	-0.2	-0.4	-0.7	-0.5	1.1	-0.2	-0.2	-0.3	-0.4	-0.3	-0.3
Illnesses of siblings	0.2	0.3	0.9	-0.7	-0.6	-0.7	-0.6	-1.0	-0.3	-0.1	0.4	-0.0	-0.6	-0.0	-0.2
Worrier / anxious feelings	0.2	0.3	1.4	0.3	-0.4	-0.2	-0.2	-0.0	0.2	1.2	0.6	1.1	-0.1	-0.8	-0.0
Hair/balding pattern: Pattern 3	0.2	0.3	1.4	0.4	-0.7	-0.0	-0.1	-0.0	-0.1	0.8	-1.2	0.6	0.6	-0.4	-0.3
Pulse rate	0.2	0.3	0.8	-0.6	0.6	-0.6	-0.2	-0.5	-0.0	-0.8	-0.5	-0.6	-0.9	0.4	0.9
Happiness	0.2	0.3	1.4	0.2	-0.0	-0.5	-0.0	-0.5	0.9	0.3	1.2	0.3	-0.3	0.2	-0.1
Mouth/teeth dental problems: Dentures	0.2	0.3	1.5	-0.1	0.9	-0.3	-0.4	-0.4	0.9	-0.2	0.3	0.0	-0.6	-1.2	0.2
Asthma	0.2	0.3	0.9	0.2	0.5	0.8	0.7	0.7	0.5	-0.2	0.8	0.0	0.1	-0.5	1.0
Headache pain in last month	0.2	0.3	1.4	-0.5	-0.7	-0.1	-0.4	-0.2	0.5	-0.5	1.2	-0.5	-0.5	0.6	-0.3
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.7	-0.4	-0.8	-0.8	-0.2	-0.7	-0.2	-0.2	0.8	-0.1	-0.5	0.4	-0.7
Wheeze or whistling in the chest in last year	0.2	0.3	2.0	0.3	0.4	0.8	0.2	0.8	0.2	-0.1	-0.0	-0.0	0.0	-0.1	1.4
Medication: Blood pressure	0.2	0.4	2.3	0.5	1.1	-0.1	0.5	0.0	0.6	-0.1	-0.7	-0.4	0.4	1.5	-0.1
Suffer from ‘nerves’	0.2	0.3	1.0	-0.2	-1.0	-0.3	-0.7	-0.1	0.9	0.4	-0.4	0.8	-0.3	-0.8	-0.3
Number of self-reported non-cancer illnesses	0.2	0.4	1.1	-0.4	-0.4	-0.6	-1.0	-0.7	1.0	-0.2	-0.9	-0.2	-0.7	0.2	0.4
Financial situation satisfaction	0.2	0.3	1.5	-0.3	0.2	-0.5	-0.3	-0.6	0.1	0.1	1.2	0.0	-0.5	0.0	0.9
Commuting to job workplace: Public transport	0.2	0.3	0.7	0.4	0.3	0.5	0.7	0.5	0.7	-0.5	0.8	-0.4	0.3	0.5	-0.4
Number of operations (self-reported)	0.2	0.3	1.5	0.5	0.3	0.4	0.4	0.2	1.2	-0.2	0.6	-0.4	0.2	0.6	0.9
Schizophrenia (2018)	0.1	0.3	1.4	-0.4	-0.5	-0.3	-0.1	-0.3	-0.8	0.4	0.1	0.7	0.2	-1.2	-0.5
Crohns Disease (2017)	0.1	0.3	1.3	-0.5	1.1	-0.7	-0.2	-0.8	-0.6	-0.2	0.1	-0.3	-0.3	0.1	-0.2
Prostate Cancer	0.1	0.1	0.3	0.3	-0.2	0.4	0.0	0.2	-0.2	0.5	-0.6	0.4	0.2	-0.2	-0.4
Primary Biliary Cirrhosis	0.1	0.1	0.3	-0.3	-0.1	-0.3	-0.6	-0.3	0.1	0.5	-0.5	0.4	-0.1	0.4	-0.3
Blood Platelet Count	0.1	1.5	6.9	-0.5	-2.6	-1.2	-0.6	-1.0	1.7	-0.4	0.0	-0.6	-0.4	0.7	-2.1
Blood Red Count	0.1	1.2	6.3	0.8	0.6	1.5	1.4	1.3	0.1	-0.1	0.5	0.0	1.1	0.2	2.5
Systolic Blood Pressure	0.1	0.6	1.6	-0.2	-1.3	-0.4	-1.1	-0.2	-0.2	0.5	-1.3	0.7	0.1	-1.0	-0.7
Tanning	0.1	1.0	6.7	0.9	1.3	0.6	0.9	0.4	2.6	0.1	1.3	0.1	0.4	0.1	-0.1
Diabetes (mother)	0.1	0.1	0.9	0.2	0.5	-0.1	0.1	0.2	-0.4	0.0	0.1	-0.1	-0.0	-0.1	-0.9
Current tobacco smoking	0.1	0.1	0.3	0.1	0.5	0.0	-0.0	-0.1	0.2	0.5	0.5	0.4	-0.1	0.3	0.2
High blood pressure (mother)	0.1	0.2	0.5	-0.1	0.4	0.4	-0.6	0.2	-0.7	0.3	-0.4	0.2	-0.3	-0.4	-0.5
Pain all over the body in last month	0.1	0.1	0.5	0.3	0.1	-0.1	0.1	0.1	-0.1	0.1	-0.4	0.1	0.2	0.0	-0.7
Hip circumference	0.1	0.4	1.2	0.6	-0.9	-0.0	0.4	-0.1	-0.5	0.3	-0.9	0.5	0.6	-0.7	-1.1
Peak expiratory flow (PEF)	0.1	0.3	1.8	-0.0	-0.2	0.5	0.1	0.5	0.2	-0.1	0.5	0.4	-0.3	-1.3	-0.5
Medication for pain relief, constipation, heartburn	0.1	0.2	0.6	-0.6	-0.2	-0.8	-0.5	-0.6	-0.2	-0.0	0.2	-0.0	-0.5	0.3	0.2
Leg fat mass (right)	0.1	0.3	1.2	-0.0	-0.8	-0.2	-0.1	-0.3	-0.4	-0.3	-0.3	-0.2	0.0	-0.8	-1.1
Pulse rate, automated reading	0.1	0.4	2.4	-0.4	-0.4	-0.3	-0.2	-0.3	-1.0	-0.0	-1.6	0.1	-0.4	-0.1	0.5
Age at last live birth	0.1	0.2	0.8	-0.1	-0.0	0.4	0.2	0.2	0.5	-0.3	0.9	-0.3	-0.5	0.4	0.7
Supplements: Vitamin C	0.1	0.2	0.5	0.0	0.1	-0.5	0.1	-0.6	0.6	-0.2	-0.1	0.1	0.1	-0.7	0.7
Asthma (self-reported)	0.1	0.3	0.9	0.1	0.4	0.5	0.6	0.5	0.7	-0.4	0.9	-0.3	-0.1	-0.1	0.8
Smoking status: Current	0.1	0.1	0.7	-0.2	0.3	-0.2	-0.2	-0.3	0.2	0.4	0.9	0.3	-0.3	0.4	-0.1
Medication: Blood pressure	0.1	0.2	1.4	-0.0	-0.1	-0.1	-0.5	-0.2	0.4	0.3	-0.7	0.5	-0.1	-1.2	-0.4
Medication: Bendroflumethiazide	0.1	0.1	0.4	0.1	0.0	-0.3	-0.3	-0.4	-0.4	0.3	-0.1	0.2	0.3	0.4	-0.6
Irritability	0.1	0.1	0.9	0.3	0.5	0.2	0.3	0.4	0.9	-0.2	-0.0	-0.2	0.2	0.1	0.4
Pain experienced in last month	0.1	0.2	1.4	-0.1	-0.2	-0.2	-0.3	-0.3	-1.2	0.1	-0.9	0.4	-0.0	-0.3	0.0
Leg fat mass (left)	0.1	0.3	1.2	0.3	-0.6	0.1	0.1	-0.0	-0.5	0.0	-0.1	0.2	0.3	-1.1	-1.0
Blood Eosinophil Count	0.0	0.4	2.0	0.4	-0.2	0.6	0.9	0.3	-0.1	-0.2	1.4	-0.3	0.2	-0.1	0.9
BMI	0.0	0.2	1.0	0.2	-0.4	-0.2	0.1	-0.2	-0.4	-0.1	0.0	0.1	0.3	-0.9	-1.0
Body mass index (BMI)	0.0	0.1	0.7	0.0	-0.8	-0.3	-0.2	-0.3	0.1	-0.1	-0.1	-0.1	-0.0	-0.3	-0.4
Trunk fat mass	0.0	0.1	0.2	0.1	-0.4	0.1	0.1	0.0	-0.1	-0.4	-0.0	-0.3	0.0	-0.4	-0.4
Arm fat mass (right)	0.0	0.1	0.5	0.1	-0.7	0.0	-0.1	-0.0	-0.1	-0.4	-0.2	-0.2	-0.0	-0.4	-0.4
Whole body fat mass	0.0	0.1	0.5	-0.0	-0.7	-0.2	-0.1	-0.2	-0.1	-0.5	-0.1	-0.4	-0.1	-0.4	-0.7
Arm fat mass (left)	0.0	0.1	0.3	0.3	-0.5	0.2	0.1	0.2	-0.3	-0.1	-0.2	0.0	0.3	-0.6	-0.4

Hub : Genes

SNX13

Models

Trait associations