Best TWAS P=4.63e-10 · Best GWAS P=5.07e-11 conditioned to 0.0322
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | KCTD9 | 0.11 | 0.07 | lasso | 5 | 0.06 | 7.9e-07 | -5.7 | -6.1 | 8.2e-10 | 0.85 | 0.13 | 0.86 | FALSE |
2 | YFS | Blood | KCTD9 | 0.04 | 0.04 | lasso | 8 | 0.04 | 7.8e-12 | -5.2 | 5.2 | 2.3e-07 | -0.65 | 0.98 | 0.02 | FALSE |
3 | The Cancer Genome Atlas | Lung Adenocarcinoma | KCTD9 | 0.03 | 0.01 | blup | 75 | 0.01 | 1.1e-02 | -6.4 | -6.2 | 4.6e-10 | 0.92 | 0.02 | 0.72 | TRUE |