Best TWAS P=1.33e-09 · Best GWAS P=1.32e-11 conditioned to 3.03e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | R3HCC1 | 0.03 | 0.01 | lasso | 6 | 0.01 | 5.3e-04 | -5.8 | 5.6 | 2.6e-08 | 0.01 | 0.14 | 0.83 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | STC1 | 0.04 | 0.05 | enet | 7 | 0.06 | 8.9e-12 | -6.2 | 6.1 | 1.3e-09 | 0.03 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CHMP7 | 0.10 | 0.02 | lasso | 6 | 0.04 | 5.4e-05 | 2.8 | -5.9 | 4.7e-09 | -0.05 | 0.00 | 0.99 | TRUE |