[Hub]/) : Traits : Trunk predicted mass :

chr15:73,524,629-76,650,702

Best TWAS P=7.05e-13 · Best GWAS P=2.37e-13 conditioned to 2.8e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MAN2C1 0.13 0.17 lasso 5 0.18 2.5e-21 5.3 5.9 3.9e-09 0.02 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous NEIL1 0.05 0.03 lasso 5 0.02 1.6e-02 5.3 5.3 1.3e-07 0.04 0.03 0.97 FALSE
3 GTEx Adipose Subcutaneous SNUPN 0.09 0.08 lasso 4 0.07 4.2e-06 -4.5 5.3 1.1e-07 0.03 0.54 0.43 FALSE
4 GTEx Adipose Visceral Omentum MAN2C1 0.46 0.52 lasso 5 0.52 1.8e-31 5.3 5.3 9.2e-08 0.03 0.02 0.98 FALSE
5 GTEx Adipose Visceral Omentum SNUPN 0.14 0.12 enet 7 0.11 2.0e-06 -4.5 5.7 1.4e-08 0.04 0.50 0.45 FALSE
6 GTEx Adipose Visceral Omentum CTD-2323K18.1 0.14 0.13 lasso 5 0.10 4.1e-06 -4.5 5.3 1.2e-07 0.03 0.63 0.35 FALSE
7 GTEx Adrenal Gland MAN2C1 0.20 0.24 lasso 6 0.21 4.3e-08 5.6 5.3 8.9e-08 0.04 0.02 0.98 FALSE
8 GTEx Adrenal Gland SNUPN 0.17 0.05 enet 17 0.11 1.3e-04 -3.5 7.2 7.1e-13 0.08 0.04 0.39 TRUE
9 GTEx Artery Aorta MAN2C1 0.48 0.60 lasso 5 0.59 7.1e-40 5.5 5.5 4.0e-08 0.04 0.02 0.98 FALSE
10 GTEx Artery Coronary MAN2C1 0.54 0.39 lasso 7 0.35 1.7e-12 5.5 5.3 1.0e-07 0.04 0.02 0.98 FALSE
11 GTEx Artery Coronary SNUPN 0.19 0.00 enet 8 0.02 6.2e-02 -4.5 5.6 1.9e-08 0.05 0.04 0.10 FALSE
12 GTEx Artery Coronary CTD-2323K18.1 0.21 0.13 lasso 5 0.13 4.9e-05 -4.5 5.4 8.7e-08 0.03 0.13 0.18 FALSE
13 GTEx Artery Tibial MAN2C1 0.33 0.45 lasso 4 0.44 9.2e-38 5.5 5.4 5.1e-08 0.03 0.02 0.98 FALSE
14 GTEx Brain Caudate basal ganglia MAN2C1 0.23 0.24 enet 20 0.22 7.9e-07 5.5 5.4 8.2e-08 0.05 0.02 0.98 FALSE
15 GTEx Brain Cerebellar Hemisphere MAN2C1 0.23 0.15 lasso 5 0.15 1.2e-04 3.9 5.2 2.3e-07 0.07 0.03 0.85 FALSE
16 GTEx Brain Frontal Cortex BA9 MAN2C1 0.27 0.25 lasso 3 0.21 2.8e-06 5.5 5.5 3.8e-08 0.04 0.02 0.97 FALSE
17 GTEx Brain Hippocampus MAN2C1 0.21 0.26 lasso 3 0.26 9.4e-07 5.3 5.4 6.9e-08 0.03 0.02 0.96 FALSE
18 GTEx Brain Nucleus accumbens basal ganglia MAN2C1 0.14 0.17 lasso 3 0.12 3.3e-04 5.1 5.2 2.1e-07 0.03 0.03 0.95 FALSE
19 GTEx Breast Mammary Tissue MAN2C1 0.42 0.54 lasso 5 0.52 4.6e-31 5.5 5.5 4.3e-08 0.04 0.02 0.98 FALSE
20 GTEx Breast Mammary Tissue (Male) MAN2C1 0.37 0.38 lasso 3 0.34 9.7e-09 5.4 5.1 2.8e-07 0.03 0.02 0.97 FALSE
21 GTEx Breast Mammary Tissue (Male) CTD-2323K18.1 0.36 0.24 lasso 5 0.19 3.4e-05 -4.8 5.3 1.5e-07 0.01 0.11 0.40 FALSE
22 GTEx Breast Mammary Tissue (Female) MAN2C1 0.39 0.41 lasso 6 0.45 7.6e-15 5.4 5.3 9.5e-08 0.03 0.03 0.97 FALSE
23 GTEx Breast Mammary Tissue (Female) SNUPN 0.11 0.12 lasso 5 0.10 7.7e-04 -4.5 5.1 2.8e-07 0.04 0.06 0.24 FALSE
24 GTEx Cells EBV-transformed lymphocytes CTD-2323K18.1 0.39 0.13 enet 28 0.26 3.3e-09 -4.3 5.2 1.8e-07 0.04 0.28 0.51 FALSE
25 GTEx Cells Transformed fibroblasts MAN2C1 0.38 0.50 lasso 4 0.49 6.2e-42 5.5 5.4 5.8e-08 0.03 0.02 0.98 FALSE
26 GTEx Cells Transformed fibroblasts IMP3 0.05 0.06 lasso 2 0.05 1.3e-04 5.1 -5.2 1.6e-07 -0.05 0.04 0.92 FALSE
27 GTEx Colon Sigmoid MAN2C1 0.36 0.46 lasso 3 0.45 1.9e-17 5.3 5.3 9.3e-08 0.03 0.02 0.98 FALSE
28 GTEx Colon Transverse MAN2C1 0.42 0.55 lasso 6 0.54 8.1e-30 5.6 5.5 4.1e-08 0.04 0.02 0.98 FALSE
29 GTEx Colon Transverse SNUPN 0.15 0.12 lasso 3 0.08 7.7e-05 5.5 5.6 2.6e-08 0.04 0.02 0.97 FALSE
30 GTEx Colon Transverse CTD-2323K18.1 0.13 0.04 lasso 11 0.05 1.8e-03 5.5 6.2 4.7e-10 0.04 0.03 0.92 FALSE
31 GTEx Esophagus Gastroesophageal Junction MAN2C1 0.37 0.49 lasso 2 0.49 7.3e-20 5.3 5.3 8.9e-08 0.03 0.03 0.97 FALSE
32 GTEx Esophagus Mucosa MAN2C1 0.27 0.38 lasso 2 0.39 9.9e-28 5.5 5.4 5.5e-08 0.03 0.02 0.98 FALSE
33 GTEx Esophagus Muscularis MAN2C1 0.55 0.60 lasso 3 0.62 3.6e-47 5.5 5.5 4.4e-08 0.03 0.02 0.98 FALSE
34 GTEx Heart Atrial Appendage MAN2C1 0.30 0.28 lasso 5 0.29 1.8e-13 5.3 5.4 7.8e-08 0.03 0.02 0.98 FALSE
35 GTEx Heart Left Ventricle MAN2C1 0.18 0.19 lasso 4 0.16 4.8e-09 5.5 5.5 4.8e-08 0.03 0.02 0.98 FALSE
36 GTEx Lung MAN2C1 0.33 0.51 lasso 3 0.50 2.1e-43 5.3 5.4 8.2e-08 0.03 0.03 0.97 FALSE
37 GTEx Lung SNUPN 0.14 0.06 lasso 2 0.07 2.7e-06 5.5 6.2 7.3e-10 0.04 0.03 0.97 FALSE
38 GTEx Muscle Skeletal MAN2C1 0.05 0.01 enet 6 0.03 5.6e-04 5.5 6.1 9.4e-10 0.04 0.02 0.96 FALSE
39 GTEx Nerve Tibial MAN2C1 0.37 0.52 enet 20 0.53 5.6e-44 5.5 5.4 6.2e-08 0.03 0.02 0.98 FALSE
40 GTEx Nerve Tibial CYP11A1 0.06 0.00 lasso 2 0.00 5.9e-01 -5.2 -5.2 1.7e-07 -0.03 0.65 0.02 TRUE
41 GTEx Nerve Tibial CTD-2323K18.1 0.19 0.11 lasso 7 0.10 1.6e-07 -4.5 5.4 7.9e-08 0.04 0.65 0.34 FALSE
42 GTEx Pancreas MAN2C1 0.39 0.41 lasso 1 0.39 1.0e-17 5.5 5.5 3.8e-08 0.04 0.02 0.98 FALSE
43 GTEx Pituitary MAN2C1 0.31 0.37 lasso 5 0.34 2.1e-09 5.3 5.4 6.7e-08 0.03 0.02 0.98 FALSE
44 GTEx Prostate MAN2C1 0.26 0.30 lasso 3 0.33 4.6e-09 5.3 5.4 7.2e-08 0.03 0.03 0.97 FALSE
45 GTEx Prostate CTD-2323K18.1 0.34 0.18 enet 22 0.17 4.3e-05 -4.5 5.3 1.4e-07 0.01 0.29 0.20 FALSE
46 GTEx Skin Not Sun Exposed Suprapubic MAN2C1 0.39 0.44 lasso 4 0.44 1.2e-26 5.3 5.4 5.2e-08 0.03 0.02 0.98 FALSE
47 GTEx Skin Sun Exposed Lower leg MAN2C1 0.30 0.36 enet 17 0.38 1.6e-32 5.4 5.3 1.1e-07 0.05 0.02 0.97 FALSE
48 GTEx Spleen MAN2C1 0.70 0.62 lasso 5 0.57 1.2e-17 5.5 5.2 1.5e-07 0.03 0.02 0.98 FALSE
49 GTEx Stomach MAN2C1 0.36 0.45 lasso 3 0.46 2.0e-24 5.3 5.4 5.6e-08 0.03 0.02 0.98 FALSE
50 GTEx Thyroid NEIL1 0.06 0.06 lasso 2 0.07 9.0e-06 5.4 5.4 6.8e-08 0.03 0.03 0.96 FALSE
51 GTEx Thyroid MAN2C1 0.44 0.53 lasso 6 0.55 3.1e-49 5.3 5.3 1.3e-07 0.03 0.02 0.97 FALSE
52 GTEx Thyroid SNUPN 0.15 0.10 lasso 7 0.16 6.2e-12 -4.8 6.2 4.4e-10 0.03 0.08 0.92 FALSE
53 GTEx Thyroid RP11-817O13.6 0.05 0.05 lasso 1 0.03 1.3e-03 5.4 5.4 5.4e-08 0.03 0.03 0.92 FALSE
54 GTEx Thyroid LOXL1-AS1 0.15 0.03 enet 40 0.03 2.6e-03 -2.5 6.3 2.7e-10 0.34 0.08 0.48 TRUE
55 GTEx Uterus MAN2C1 0.52 0.56 lasso 2 0.61 1.4e-15 5.3 5.4 7.7e-08 0.03 0.02 0.98 FALSE
56 GTEx Vagina MAN2C1 0.31 0.30 enet 6 0.27 5.6e-07 5.6 5.4 8.5e-08 0.03 0.02 0.98 FALSE
57 GTEx Whole Blood MAN2C1 0.28 0.29 lasso 5 0.29 3.2e-27 5.3 5.2 1.8e-07 0.02 0.02 0.98 FALSE
58 METSIM Adipose IMP3 0.04 0.01 blup 226 0.03 5.0e-05 -4.4 -5.7 1.1e-08 -0.07 0.39 0.16 FALSE
59 METSIM Adipose MAN2C1 0.22 0.41 lasso 6 0.41 1.1e-66 5.3 5.2 1.7e-07 0.04 0.03 0.97 FALSE
60 METSIM Adipose SNX33 0.10 0.05 lasso 7 0.05 6.1e-08 -4.1 -5.3 1.4e-07 -0.01 0.90 0.08 FALSE
61 NTR Blood MAN2C1 0.02 0.03 lasso 2 0.03 1.5e-10 5.3 5.3 8.9e-08 0.02 0.03 0.97 FALSE
62 The Cancer Genome Atlas Breast Invasive Carcinoma COMMD4 0.02 0.00 enet 4 0.01 1.6e-03 -4.5 -5.3 1.4e-07 0.01 0.01 0.40 FALSE
63 The Cancer Genome Atlas Breast Invasive Carcinoma SNUPN 0.04 0.02 lasso 3 0.03 3.3e-06 -4.5 6.0 1.9e-09 0.03 0.02 0.96 FALSE
64 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma MAN2C1 0.12 0.11 blup 14 0.12 1.4e-06 5.1 5.5 3.3e-08 0.02 0.00 1.00 FALSE
65 The Cancer Genome Atlas Colon Adenocarcinoma SNUPN 0.11 0.10 lasso 4 0.11 6.9e-07 5.6 5.3 1.4e-07 0.03 0.00 1.00 FALSE
66 The Cancer Genome Atlas Esophageal Carcinoma SNUPN 0.18 0.11 lasso 5 0.07 2.6e-03 5.6 5.7 1.0e-08 0.03 0.00 0.93 FALSE
67 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SNUPN 0.05 0.03 blup 38 0.05 4.0e-06 5.4 5.7 9.6e-09 0.03 0.01 0.99 FALSE
68 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma MAN2C1 0.11 0.05 lasso 5 0.09 1.2e-05 -4.5 5.8 7.9e-09 0.02 0.00 0.91 FALSE
69 The Cancer Genome Atlas Brain Lower Grade Glioma MAN2C1 0.08 0.06 blup 14 0.09 2.0e-10 5.1 5.7 9.2e-09 0.02 0.00 1.00 FALSE
70 The Cancer Genome Atlas Liver Hepatocellular Carcinoma SNUPN 0.14 0.10 lasso 4 0.08 1.1e-04 5.5 5.5 3.6e-08 0.03 0.00 0.99 FALSE
71 The Cancer Genome Atlas Lung Adenocarcinoma SNUPN 0.03 0.03 enet 8 0.02 9.9e-04 5.4 6.4 1.7e-10 0.04 0.01 0.98 FALSE
72 The Cancer Genome Atlas Pancreatic Adenocarcinoma MAN2C1 0.08 0.02 blup 14 0.04 1.3e-02 5.1 5.5 2.9e-08 0.03 0.00 0.68 FALSE
73 The Cancer Genome Atlas Prostate Adenocarcinoma MAN2C1 0.07 0.04 blup 15 0.05 6.6e-06 -4.5 5.3 1.1e-07 0.04 0.05 0.76 FALSE
74 The Cancer Genome Atlas Prostate Adenocarcinoma NEIL1 0.05 0.05 lasso 3 0.05 9.0e-06 5.2 5.2 1.5e-07 0.02 0.00 0.99 FALSE
75 The Cancer Genome Atlas Prostate Adenocarcinoma SNUPN 0.13 0.09 blup 38 0.12 6.0e-13 -4.5 6.3 3.2e-10 0.05 0.22 0.77 FALSE
76 The Cancer Genome Atlas Testicular Germ Cell Tumors GOLGA6C 0.14 0.06 lasso 2 0.13 2.6e-05 -4.4 -5.1 2.9e-07 -0.06 0.00 0.23 FALSE
77 The Cancer Genome Atlas Thyroid Carcinoma MAN2C1 0.09 0.05 blup 13 0.06 3.1e-06 -4.5 5.2 1.6e-07 0.04 0.05 0.81 FALSE
78 The Cancer Genome Atlas Thyroid Carcinoma SNUPN 0.19 0.12 enet 11 0.20 1.1e-19 -4.5 5.9 4.5e-09 0.04 0.05 0.95 FALSE