TWAS hub - NEIL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0530	0.0230	5.1e-04	0.035	NA	0.015	NA	0.016	7.1e-04	NA	2.0e-02	NA	1.6e-02
2	GTEx	Adipose Visceral Omentum	0.0920	0.0420	2.3e-03	0.031	NA	0.046	NA	0.046	9.7e-03	NA	2.0e-03	NA	2.0e-03
3	GTEx	Artery Aorta	0.1110	0.0400	5.9e-06	0.075	NA	0.070	NA	0.084	6.4e-05	NA	1.1e-04	NA	2.3e-05
4	GTEx	Cells Transformed fibroblasts	0.0970	0.0340	1.2e-06	0.094	NA	0.084	NA	0.090	1.5e-07	NA	7.0e-07	NA	3.1e-07
5	GTEx	Esophagus Muscularis	0.0820	0.0320	1.3e-04	0.079	NA	0.051	NA	0.045	1.5e-05	NA	4.7e-04	NA	1.0e-03
6	GTEx	Nerve Tibial	0.0920	0.0301	3.5e-07	0.151	NA	0.137	NA	0.148	7.3e-11	NA	6.7e-10	NA	1.2e-10
7	GTEx	Thyroid	0.0580	0.0260	5.7e-04	0.062	NA	0.062	NA	0.066	1.5e-05	NA	1.6e-05	NA	9.0e-06
8	TCGA	Brain Lower Grade Glioma	0.1013	0.0469	1.2e-07	0.028	0.064	0.070	NA	0.059	3.3e-04	8.7e-08	2.0e-08	NA	2.5e-07
9	TCGA	Prostate Adenocarcinoma	0.0506	0.0285	1.4e-04	0.049	0.042	0.047	NA	0.048	7.1e-06	3.1e-05	1.2e-05	NA	9.0e-06
10	TCGA	Soft Tissue Sarcoma	0.0490	0.0310	5.3e-03	0.031	0.017	0.023	NA	0.013	6.1e-03	3.3e-02	1.6e-02	NA	5.2e-02
11	TCGA	Thyroid Carcinoma	0.1020	0.0460	2.0e-13	0.103	0.124	0.120	NA	0.052	3.2e-10	4.7e-12	1.0e-11	NA	7.7e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Eye problems/disorders: None of the above	9.1	10.5	13.2	-2.7	-2.5	-3.3	-3.6	-3.6	-3.4	-2.5	-3.6	-2.7	-3.6	-3.6
Height	7.6	146.3	225.0	15.0	13.7	12.8	9.9	9.7	8.2	14.5	12.3	14.3	9.8	10.5
Mineral and other dietary supplements	6.9	9.3	11.1	-3.1	-2.8	-2.8	-3.0	-3.1	-2.9	-3.2	-2.8	-3.3	-3.0	-3.3
Commuting to job workplace: Cycle	6.4	7.7	14.1	3.7	3.5	2.5	2.3	2.3	1.8	3.6	1.7	3.3	2.3	2.4
Standing height	5.9	58.9	99.5	10.0	8.8	8.0	6.1	6.1	5.0	9.5	7.3	9.3	6.0	6.4
Average weekly fortified wine intake	5.4	6.3	9.6	3.0	3.1	2.8	2.1	2.1	1.8	2.8	2.5	2.7	2.2	2.3
Forced vital capacity (FVC)	5.4	20.7	43.6	6.6	5.8	4.1	3.1	3.0	2.4	6.0	3.9	5.9	3.1	3.7
Mother’s age at death	5.3	6.6	12.8	3.4	3.5	2.7	1.5	1.2	0.8	3.6	2.3	3.5	1.4	2.1
Ever depressed for a whole week	5.3	6.5	9.3	-2.8	-3.0	-3.0	-2.6	-2.2	-2.2	-3.0	-1.3	-2.4	-2.4	-2.7
Type 2 Diabetes (T2D) (2018)	5.1	9.6	22.8	-4.8	-4.5	-2.8	-0.9	-1.1	-0.3	-4.6	-2.4	-4.6	-0.9	-1.7
Falls in the last year	5.0	6.7	10.7	1.5	1.6	2.5	3.1	3.3	3.2	1.5	2.6	1.7	3.2	3.1
Fasting Glucose	4.9	5.9	9.3	-2.3	-2.0	-3.0	-2.8	-3.0	-2.7	-2.4	0.0	0.0	-2.8	-2.9
Vitamin and mineral supplements	4.9	6.7	8.1	-2.6	-2.3	-2.3	-2.5	-2.7	-2.4	-2.7	-2.8	-2.8	-2.6	-2.6
Forced vital capacity (FVC), Best measure	4.9	18.1	38.4	6.2	5.5	3.9	2.8	2.7	2.0	5.7	3.5	5.6	2.8	3.4
Alzheimer’s Disease (in mother)	4.8	5.6	7.2	2.7	2.3	2.3	2.4	2.4	2.3	2.3	2.2	2.5	2.3	2.4
Hand grip strength (right)	4.8	13.1	26.3	5.1	5.1	3.5	2.6	2.6	1.9	4.9	2.2	4.4	2.6	3.0
Breast Cancer	4.7	11.3	26.4	4.9	5.1	2.4	1.4	0.9	0.5	5.0	2.8	5.0	1.3	2.2
Sitting height	4.6	32.6	71.7	8.5	7.8	5.1	3.1	2.9	1.9	8.0	5.2	7.9	3.1	3.9
Medication: Gliclazide	4.2	4.8	10.3	-3.2	-2.7	-2.0	-1.2	-1.4	-1.1	-3.0	-2.0	-3.0	-1.2	-1.4
Supplements: Zinc	4.1	4.4	5.8	1.9	2.2	1.9	2.2	2.1	2.0	2.4	1.5	2.3	2.2	2.4
Ever highly irritable/argumentative for 2 days	4.1	4.9	11.0	-3.3	-3.3	-2.2	-1.0	-0.9	-0.3	-3.3	-1.3	-3.2	-0.9	-1.3
Ever unenthusiastic/disinterested for a whole week	4.0	4.9	6.4	-2.0	-2.4	-2.5	-2.4	-2.1	-2.2	-2.3	-1.4	-1.9	-2.3	-2.5
Eye problems/disorders: Cataract	4.0	4.6	5.4	2.2	2.0	2.3	2.2	2.2	1.9	2.0	2.3	2.1	2.1	2.2
Ever had hysterectomy (womb removed)	3.9	4.4	6.0	-1.9	-2.2	-2.2	-2.1	-2.1	-2.0	-2.1	-1.6	-2.0	-2.2	-2.5
Supplements: Glucosamine	3.8	4.9	8.7	1.6	1.6	2.0	2.7	2.9	2.8	1.5	1.6	1.5	2.7	2.5
Average weekly beer plus cider intake	3.8	5.4	7.1	-2.1	-1.7	-2.4	-2.6	-2.6	-2.5	-2.0	-2.7	-2.0	-2.5	-2.3
Medication: Atenolol	3.7	4.6	6.5	-2.3	-2.2	-2.1	-2.0	-2.5	-2.2	-2.0	-1.6	-2.1	-2.2	-2.3
Serious illness, injury or assault of a close relative in last 2 years	3.7	4.3	6.5	-2.4	-2.5	-2.5	-1.7	-1.5	-1.5	-2.5	-1.7	-2.5	-1.6	-2.1
Supplements: Fish oil (including cod liver oil)	3.7	4.8	7.3	2.2	1.7	1.8	2.1	2.1	2.0	2.3	2.7	2.5	2.1	2.4
Wears glasses or contact lenses	3.5	4.1	6.0	1.4	1.0	2.2	2.4	2.5	2.4	1.4	2.2	1.5	2.3	2.3
Diabetes (self-reported)	3.3	5.1	13.9	-3.7	-3.1	-2.0	-0.6	-0.7	-0.1	-3.5	-1.5	-3.4	-0.6	-1.2
Illnesses of siblings	3.3	4.7	6.2	2.5	1.9	2.1	2.3	2.2	2.0	2.4	1.2	2.1	2.3	2.5
Forced expiratory volume in 1-second (FEV1)	3.3	11.0	23.4	4.8	4.5	2.6	2.0	2.0	1.4	4.6	2.7	4.6	2.0	2.7
Illnesses of siblings: Diabetes	3.3	4.0	6.7	-1.7	-1.4	-2.0	-2.5	-2.4	-2.6	-1.3	-1.4	-1.3	-2.5	-2.2
Coronary Artery Disease (CAD)	3.2	3.8	8.4	-1.6	0.0	-1.6	-2.7	-2.7	-2.9	-1.3	0.0	0.0	-2.7	-2.2
Diabetes (mother)	3.2	4.0	7.8	-2.8	-2.7	-2.0	-1.2	-1.2	-0.7	-2.8	-1.9	-2.7	-1.2	-1.4
Current tobacco smoking	3.2	5.2	9.4	-1.5	-1.2	-2.2	-2.7	-3.1	-2.9	-1.5	-1.9	-1.4	-2.9	-2.7
Eye problems/disorders: Glaucoma	3.2	3.7	5.9	2.0	1.4	1.5	2.1	1.9	1.8	1.8	2.4	1.9	2.1	2.2
LDL Cholesterol	3.1	4.9	9.3	1.7	1.6	2.5	2.8	3.0	2.8	1.5	0.0	0.0	2.8	2.6
Forced expiratory volume in 1-second (FEV1), Best measure	3.0	9.7	21.0	4.6	4.3	2.4	1.8	1.6	1.1	4.5	2.5	4.4	1.7	2.5
Average weekly spirits intake	2.9	3.5	5.3	1.5	1.5	1.9	2.1	2.0	1.9	1.6	2.3	1.7	2.0	2.0
Hypothyroidism/myxoedema (self-reported)	2.9	5.6	10.7	3.0	2.6	2.0	1.7	1.9	1.4	3.2	2.3	3.3	1.6	2.0
Blood Platelet Count	2.8	32.3	77.3	-8.4	-8.4	-4.5	-2.2	-1.8	-0.6	-8.8	-3.9	-8.6	-2.2	-3.8
Blood White Count	2.8	20.8	34.6	-5.7	-5.5	-4.4	-3.4	-3.4	-2.6	-5.8	-4.5	-5.9	-3.4	-4.0
Multivitamins +/- minerals	2.7	3.5	5.4	1.6	1.3	1.5	2.0	2.3	2.1	1.6	1.6	1.7	2.2	2.2
Forced expiratory volume in 1-second (FEV1), predicted	2.6	5.3	11.0	3.3	2.7	2.5	1.9	1.9	1.6	2.8	1.5	2.6	1.9	1.9
Smoking status: Current	2.6	4.1	7.7	-1.3	-1.0	-1.9	-2.5	-2.8	-2.6	-1.3	-1.6	-1.1	-2.6	-2.4
Hearing aid user	2.6	2.9	4.7	1.7	1.6	1.4	1.5	1.8	1.4	1.9	2.2	2.0	1.5	1.7
Myopia	2.6	3.8	5.8	-1.2	-0.8	-1.7	-2.3	-2.3	-2.4	-1.2	-2.4	-1.4	-2.4	-2.3
Comparative height size at age 10	2.5	13.6	19.4	4.4	4.1	3.9	3.2	3.0	2.7	4.3	4.0	4.2	3.2	3.2
Smoking status: Previous	2.5	3.7	4.9	2.1	2.2	1.8	1.7	1.6	1.5	2.1	2.1	2.2	1.7	1.9
Medication: Metformin	2.4	3.4	10.9	-3.3	-2.6	-1.4	-0.1	-0.2	0.4	-2.9	-0.5	-2.8	-0.0	-0.6
Had menopause	2.4	3.0	4.9	2.1	2.0	1.5	1.3	1.3	1.1	2.0	2.1	2.2	1.4	1.5
Father’s age at death	2.4	3.3	5.6	1.7	1.5	1.8	2.0	2.4	1.9	1.6	1.3	1.6	2.0	2.0
Diabetes diagnosed by doctor	2.4	3.9	11.0	-3.3	-2.8	-1.8	-0.4	-0.5	0.1	-3.0	-1.4	-3.0	-0.3	-0.9
Glaucoma (self-reported)	2.3	2.7	3.9	1.6	0.8	1.3	1.9	1.8	1.7	1.3	2.0	1.4	2.0	2.0
Fractured/broken bones in last 5 years	2.3	2.9	5.1	2.3	2.1	1.4	1.3	1.3	1.2	2.2	1.0	2.2	1.4	1.8
Waist Hip Ratio (WHR)	2.2	9.8	23.4	-4.1	-4.8	-2.6	-1.0	-0.6	-0.3	-4.2	-4.2	-4.4	-1.1	-1.7
Trunk predicted mass	2.2	12.3	29.1	5.3	5.0	3.0	1.3	1.4	0.4	5.4	2.6	5.2	1.2	2.1
Trunk fat-free mass	2.1	12.1	29.0	5.3	5.0	3.0	1.2	1.4	0.3	5.4	2.6	5.2	1.1	2.0
Peak expiratory flow (PEF)	2.1	4.8	11.7	3.3	3.4	1.2	0.5	0.2	-0.1	3.4	1.6	3.4	0.6	1.3
Medication: Allopurinol	2.1	2.8	6.6	2.3	2.2	0.0	-0.8	-1.0	-1.5	2.4	1.8	2.6	-0.8	-0.4
Qualifications: CSEs or equivalent	2.0	2.6	6.9	-1.0	-1.4	-1.7	-1.6	-1.6	-1.7	-1.2	-2.6	-1.4	-1.7	-1.4
Medication: Omeprazole	1.9	2.3	3.8	1.3	1.5	1.5	1.3	1.1	1.1	1.6	1.8	1.9	1.3	1.8
Lupus	1.8	2.8	5.0	-1.6	-1.1	-1.9	-2.0	-2.2	-1.9	-1.5	-1.1	0.0	-1.8	-1.9
Lung FEV1/FVC ratio	1.8	9.2	15.4	-2.5	-1.3	-3.1	-3.6	-3.9	-3.9	-1.9	-3.2	-1.8	-3.7	-3.0
Hand grip strength (left)	1.8	4.7	13.8	3.5	3.7	1.8	0.9	0.8	0.2	3.3	0.8	2.8	0.7	1.2
Mouth/teeth dental problems: Dentures	1.8	3.1	7.2	0.1	0.3	1.9	2.4	2.3	2.7	0.0	1.7	0.3	2.3	2.1
Medication: Ibuprofen	1.8	2.1	4.5	0.5	0.7	1.4	1.7	2.0	2.1	0.1	2.1	0.6	1.7	1.3
Supplements: Vitamin C	1.8	2.1	6.1	1.6	1.5	0.9	0.8	0.8	0.6	1.9	2.5	2.2	0.8	1.0
Mood swings	1.8	3.3	8.5	-2.9	-2.7	-1.8	-0.6	-0.7	-0.0	-2.7	-1.5	-2.5	-0.5	-0.9
Maternal smoking around birth	1.7	2.4	3.6	-1.4	-0.8	-1.4	-1.7	-1.6	-1.8	-1.2	-1.6	-1.5	-1.8	-1.9
Suffer from ‘nerves’	1.7	2.7	5.1	-2.1	-2.2	-1.8	-1.3	-1.1	-0.9	-2.3	-0.9	-2.0	-1.1	-1.5
Medication: Paracetamol	1.7	2.6	6.5	-0.8	-0.5	1.4	2.2	2.3	2.5	-0.7	1.4	-0.7	2.0	1.6
Arm predicted mass (left)	1.7	8.6	19.5	4.2	4.0	2.6	1.3	1.5	0.6	4.4	2.5	4.3	1.2	2.0
Alzheimer’s Disease (including proxy)	1.6	2.4	3.1	1.7	1.3	1.6	1.5	1.7	1.5	1.3	1.4	1.5	1.6	1.6
Lung FVC	1.6	8.2	21.0	4.6	4.6	1.6	0.5	0.4	-0.3	4.5	1.9	4.4	0.5	1.3
Stomach or abdominal pain in last month	1.6	2.0	5.0	0.1	-0.2	1.4	1.9	2.0	2.2	0.0	1.1	0.1	1.8	1.6
Past tobacco smoking	1.6	2.9	6.7	-2.3	-2.6	-1.3	-0.9	-0.7	-0.5	-2.3	-1.8	-2.4	-0.9	-1.3
Impedance of arm (left)	1.6	7.3	15.1	1.4	0.7	3.0	3.7	3.3	3.9	0.8	2.5	0.8	3.7	2.9
Arm predicted mass (right)	1.6	8.2	19.2	4.2	4.0	2.4	1.1	1.3	0.3	4.4	2.4	4.3	1.0	1.8
Whole body water mass	1.6	9.3	22.3	4.6	4.4	2.6	1.0	1.2	0.2	4.7	2.3	4.6	0.9	1.8
Depressed Affect (Nagel 2018)	1.5	3.2	8.3	-2.9	-2.8	-1.6	-0.6	-0.6	-0.0	-2.7	-1.3	-2.3	-0.6	-0.9
Hypothyroidism (self reported)	1.5	3.4	6.8	2.4	2.2	1.3	1.2	1.6	1.1	2.6	1.5	2.6	1.2	1.6
Impedance of leg (left)	1.5	7.1	18.0	0.3	-0.0	2.5	3.8	3.4	4.2	-0.1	2.5	-0.1	3.8	2.9
Birth weight of first child	1.5	2.6	5.6	-1.4	-1.6	0.7	1.7	2.2	2.4	-1.6	-1.2	-1.8	1.7	1.1
Arm fat-free mass (right)	1.5	7.8	18.5	4.1	4.0	2.3	1.0	1.2	0.3	4.3	2.3	4.2	0.9	1.6
Whole body fat-free mass	1.5	8.7	21.1	4.5	4.2	2.5	1.0	1.2	0.1	4.6	2.1	4.5	0.9	1.7
Impedance of whole body	1.5	7.8	18.0	1.0	0.4	2.9	3.9	3.5	4.2	0.4	2.5	0.4	3.9	3.0
Bilateral oophorectomy (both ovaries removed)	1.4	1.6	3.1	-1.3	-1.2	-1.5	-0.8	-0.9	-0.7	-1.6	-1.6	-1.8	-0.9	-1.2
Medication: Levothyroxine sodium	1.4	2.3	5.1	2.0	1.5	1.1	1.0	1.2	0.9	2.1	1.7	2.3	1.0	1.1
Impedance of arm (right)	1.4	6.5	13.6	1.2	0.6	3.0	3.5	3.1	3.7	0.7	2.2	0.7	3.5	2.8
Loud music exposure frequency	1.4	1.6	3.2	-1.3	-1.8	-1.3	-1.1	-1.0	-0.9	-1.4	-0.6	-1.3	-1.1	-1.4
Pain type(s) experienced in last month: Hip pain	1.4	1.8	3.7	0.2	0.3	1.3	1.7	1.9	1.9	0.3	1.6	0.3	1.7	1.4
Medication: Omeprazole (e.g. Zanprol)	1.4	1.7	3.2	1.5	1.7	1.4	0.9	0.8	0.7	1.6	1.2	1.8	0.9	1.4
Depression (Nagel 2018)	1.3	2.0	4.6	-2.1	-1.9	-1.4	-0.8	-0.8	-0.4	-1.9	-1.3	-1.9	-0.7	-0.9
Blood Red Count	1.3	12.2	18.1	-4.0	-3.3	-4.2	-3.1	-3.8	-2.6	-3.8	-2.7	-3.9	-3.1	-3.3
Impedance of leg (right)	1.3	6.3	15.1	0.4	-0.0	2.4	3.5	3.1	3.9	0.0	2.4	0.0	3.5	2.7
Financial difficulties in last 2 years	1.3	1.8	3.8	0.6	0.7	1.3	1.5	2.0	1.8	0.4	1.5	0.7	1.7	1.6
Mouth/teeth dental problems	1.3	2.0	3.5	-0.7	-1.0	-1.7	-1.7	-1.9	-1.8	-0.7	-0.9	-0.8	-1.7	-1.7
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.2	7.2	-2.7	-2.1	-0.6	0.3	0.6	0.9	-2.4	-0.0	-2.1	0.3	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	4.3	-1.8	-2.1	-1.7	-1.2	-1.0	-0.9	-1.8	-0.6	-1.4	-1.1	-1.3
Headache pain in last month	1.3	2.3	4.0	-1.1	-1.1	-2.0	-1.7	-1.7	-1.5	-1.5	-1.1	-1.3	-1.7	-1.6
Emphysema/chronic bronchitis	1.3	1.4	2.7	1.1	0.8	1.1	1.4	1.5	1.2	1.3	0.0	1.0	1.4	1.6
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	4.0	-0.5	-0.0	-1.1	-1.8	-1.8	-2.0	-0.1	-0.3	0.1	-1.9	-1.4
Loneliness, isolation	1.3	1.8	3.1	-1.8	-1.8	-1.4	-1.0	-1.0	-0.8	-1.5	-1.4	-1.6	-1.1	-1.1
Basal metabolic rate	1.3	7.1	16.4	3.9	3.7	2.4	1.1	1.3	0.4	4.0	2.1	4.0	1.0	1.7
Arm fat-free mass (left)	1.3	6.7	16.0	3.8	3.6	2.2	0.9	1.1	0.2	4.0	2.2	3.9	0.8	1.5
Medication: Co-codamol	1.2	1.3	3.0	0.3	0.2	1.6	1.5	1.7	1.6	0.4	0.5	0.2	1.4	1.3
Severe depression (siblings)	1.2	1.3	3.5	1.8	1.6	0.2	-0.4	-0.4	-0.8	1.6	1.2	1.9	-0.4	-0.2
Lung cancer (father)	1.2	1.4	3.3	-0.1	-0.2	-1.0	-1.7	-1.7	-1.8	-0.1	-0.6	0.1	-1.7	-1.4
Hair/balding pattern: Pattern 4	1.2	3.0	4.0	-1.6	-1.4	-1.7	-1.8	-1.8	-1.9	-1.5	-2.0	-1.6	-2.0	-1.8
Alcohol intake frequency.	1.2	2.7	6.2	-2.5	-2.4	-1.0	-0.8	-1.1	-0.4	-2.5	-0.7	-2.4	-0.8	-1.4
Major Depression (MDD)	1.1	1.3	2.3	-0.9	-0.8	-1.3	-1.5	-1.5	-1.5	-0.9	0.0	0.0	-1.5	-1.3
Neuroticism	1.1	2.6	6.2	-2.5	-2.4	-1.6	-0.8	-0.8	-0.4	-2.4	-1.1	-2.2	-0.7	-1.1
Medication for hormone replacement therapy	1.1	1.3	3.0	1.7	0.9	0.9	1.0	1.3	1.1	1.2	0.8	1.1	1.0	1.0
Had other major operations	1.1	1.4	3.3	-1.8	-1.4	-0.9	-0.4	-0.4	-0.1	-1.8	-1.3	-1.8	-0.4	-0.7
Medication: Simvastatin	1.1	1.7	4.6	-2.1	-1.5	-1.2	-0.6	-0.9	-0.5	-1.8	-0.9	-1.7	-0.8	-1.0
Birth weight	1.1	2.5	3.5	1.7	1.7	1.5	1.5	1.1	1.2	1.8	1.3	1.9	1.6	1.8
Chronic bronchitis/emphysema (mother)	1.1	1.2	2.3	-0.9	-0.8	-0.7	-1.2	-1.2	-1.3	-0.9	-1.5	-0.9	-1.3	-1.2
Leg fat percentage (right)	1.1	3.9	11.5	-3.4	-3.2	-0.9	0.2	0.4	0.9	-3.2	-0.1	-2.9	0.1	-0.4
Medication: Seretide 50 evohaler	1.1	1.3	3.1	0.6	0.2	0.9	1.4	1.7	1.8	0.3	0.4	0.2	1.6	1.3
Overall health rating	1.1	2.4	6.4	-2.5	-2.5	-1.1	-0.4	-0.5	-0.1	-2.4	-0.8	-2.2	-0.5	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.8	-0.1	-0.6	1.1	1.4	1.5	1.7	-0.2	1.4	-0.1	1.5	1.3
Average weekly champagne plus white wine intake	1.1	1.5	2.3	-1.1	-1.1	-1.4	-1.3	-1.0	-1.3	-1.0	-1.2	-1.1	-1.3	-1.5
Guilty feelings	1.1	1.6	3.9	2.0	1.6	0.0	-0.9	-0.8	-1.3	1.7	0.9	1.9	-0.8	-0.5
Ever had prostate specific antigen (PSA) test	1.1	1.2	2.5	1.2	1.6	1.4	0.9	1.0	0.8	1.2	1.0	1.2	0.9	0.9
Diastolic blood pressure, automated reading	1.1	3.3	10.1	-0.3	-0.6	-1.7	-2.3	-3.2	-2.6	-0.1	-0.9	-0.3	-2.3	-2.1
Unable to work because of sickness or disability	1.1	1.5	3.2	0.4	0.1	1.3	1.6	1.7	1.8	0.2	0.6	0.3	1.7	1.6
Supplements: Calcium	1.1	1.2	1.8	-1.2	-1.1	-1.3	-1.1	-0.9	-0.9	-1.2	-0.8	-1.1	-1.0	-1.1
Mean Putamen Volume	1.0	1.1	2.2	-0.6	-0.3	-1.0	-1.4	-1.5	-1.4	-0.8	0.0	0.0	-1.4	-1.3
Schizophrenia (2014)	1.0	2.3	3.9	-1.1	-1.5	-1.6	-1.9	-1.9	-1.9	-1.3	0.0	0.0	-1.7	-2.0
Cardiovascular Disease	1.0	3.2	7.1	-1.7	-1.4	-1.9	-2.0	-2.7	-2.1	-1.4	-0.8	-1.4	-1.9	-1.9
Hip circumference	1.0	4.2	6.1	1.5	1.6	2.4	2.2	2.5	2.2	1.5	2.4	1.6	2.2	2.1
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	3.1	0.3	0.5	0.9	1.3	1.8	1.7	-0.2	1.6	0.2	1.4	1.0
Tense / ‘highly strung’	1.0	1.7	4.6	-2.1	-2.1	-1.0	-0.1	-0.1	0.4	-2.1	-0.3	-1.9	-0.0	-0.5
Neck or shoulder pain in last month	1.0	1.4	3.3	0.0	0.0	0.8	1.6	1.8	1.8	-0.1	1.3	0.1	1.6	1.2
Migraine (self-reported)	1.0	1.3	3.0	0.1	0.5	-1.1	-1.4	-1.6	-1.7	0.2	-1.3	0.1	-1.5	-1.1
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.7	-0.4	-0.8	0.3	1.3	1.4	1.6	-0.5	1.5	-0.3	1.4	1.1
Osteoarthritis (self-reported)	1.0	1.4	3.1	-1.8	-1.6	-0.3	0.7	1.0	1.2	-1.8	0.8	-1.3	0.8	0.4
Ever smoked	1.0	1.7	4.5	2.0	2.1	0.8	0.5	0.2	0.0	1.9	0.9	1.9	0.5	0.9
Leg fat percentage (left)	1.0	3.5	10.8	-3.3	-3.0	-0.9	0.2	0.5	0.9	-3.1	-0.1	-2.8	0.2	-0.3
Schizophrenia (2018)	0.9	1.9	3.3	-1.3	-1.8	-1.5	-1.5	-1.5	-1.4	-1.5	0.0	0.0	-1.4	-1.7
Chronotype (morning person)	0.9	2.1	4.8	0.3	0.5	1.3	1.9	2.2	2.2	0.3	1.0	0.1	2.1	1.7
Hearing difficulty/problems: Yes	0.9	1.4	3.2	1.0	1.2	1.1	1.1	1.8	1.3	1.0	0.7	1.0	1.3	1.3
Ever used hormone-replacement therapy (HRT)	0.9	1.2	1.9	1.3	1.4	0.9	0.9	0.7	0.6	1.4	1.0	1.3	0.9	1.1
Leg fat-free mass (left)	0.9	4.8	11.7	3.4	3.1	2.0	0.7	0.9	0.0	3.4	1.5	3.4	0.6	1.2
Age when periods started (menarche)	0.9	2.3	5.0	2.2	1.8	1.0	0.9	0.9	0.5	2.2	1.4	2.2	0.9	1.2
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	1.8	1.2	1.1	1.0	0.9	0.8	0.8	1.4	0.2	1.1	0.8	1.0
Leg predicted mass (left)	0.9	5.0	12.0	3.4	3.1	2.0	0.7	0.9	0.0	3.5	1.5	3.4	0.6	1.3
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.0	0.8	1.1	1.4	1.2	1.1	1.0	1.0	0.9	0.8	1.1	1.3
Medication: Paracetamol	0.9	1.5	3.8	-1.0	-0.7	0.8	1.5	1.7	2.0	-1.0	0.9	-1.0	1.4	1.0
Medication: Amlodipine	0.9	1.3	3.5	-0.1	-0.1	-0.7	-1.5	-1.9	-1.9	-0.1	-0.3	-0.1	-1.5	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.1	1.1	1.4	1.0	0.7	0.8	0.6	1.1	1.0	1.3	0.9	1.2
Leg fat-free mass (right)	0.9	4.5	11.5	3.3	3.1	1.8	0.5	0.8	-0.1	3.4	1.2	3.3	0.4	1.1
Back pain experienced in last month	0.9	1.3	3.4	-0.3	-0.4	0.6	1.4	1.8	1.8	-0.5	1.1	-0.3	1.5	1.1
Leg predicted mass (right)	0.9	4.7	11.9	3.4	3.2	1.8	0.5	0.8	-0.1	3.5	1.2	3.4	0.4	1.1
Financial situation satisfaction	0.9	1.1	2.8	0.3	0.2	1.0	1.4	1.7	1.7	-0.0	0.6	0.1	1.4	1.1
Alzheimer’s Disease (in father)	0.8	0.9	1.6	0.8	0.8	0.7	1.0	1.3	1.0	0.7	0.8	0.7	1.2	1.1
Heel T-Score	0.8	6.6	11.8	1.7	1.2	2.6	3.2	3.4	3.2	1.7	2.3	1.6	3.2	2.8
Frequency of depressed mood in last 2 weeks	0.8	1.2	3.0	-1.7	-1.2	-1.0	-0.4	-0.6	-0.1	-1.7	-1.0	-1.7	-0.3	-0.5
Diabetes (father)	0.8	1.0	1.8	-1.2	-0.9	0.6	1.2	1.1	1.3	-1.0	0.3	-1.0	1.1	0.7
Townsend deprivation index at recruitment	0.8	1.2	1.8	-0.6	-0.4	-1.4	-1.3	-1.3	-1.4	-0.7	-1.2	-0.6	-1.4	-1.1
Fed-up feelings	0.8	1.5	4.0	-1.9	-2.0	-0.6	0.5	0.7	1.2	-1.8	-0.5	-1.5	0.6	0.3
Gout (self-reported)	0.8	1.1	2.2	1.0	1.1	-0.1	-0.9	-1.1	-1.5	1.2	1.0	1.3	-1.0	-0.7
High blood pressure (siblings)	0.8	1.1	2.2	-0.7	-0.1	-1.1	-1.5	-1.4	-1.4	-0.6	-0.5	-0.4	-1.5	-1.4
Family relationship satisfaction	0.8	1.0	2.7	-1.5	-1.4	-0.4	0.2	0.3	0.6	-1.5	-0.7	-1.6	0.2	-0.1
Knee pain experienced in last month	0.8	1.3	4.1	-1.8	-2.0	-0.1	0.3	0.5	0.7	-1.8	0.1	-1.6	0.3	-0.2
Commuting to job workplace: Walk	0.8	0.9	3.2	1.3	1.8	0.5	0.1	0.2	-0.1	1.4	-0.2	1.3	0.2	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	4.1	2.0	2.0	0.5	0.4	0.4	0.2	1.9	1.1	1.9	0.5	0.9
Miserableness	0.8	1.4	4.0	-0.8	0.0	0.8	1.6	1.7	2.0	-0.5	0.1	-0.3	1.6	1.4
Medication: Lisinopril	0.8	1.1	2.2	-0.6	-0.7	-1.1	-1.2	-1.5	-1.2	-0.6	-1.0	-0.9	-1.1	-1.2
Cholesterol lowering medication	0.8	1.2	3.7	-1.9	-1.7	-0.8	-0.2	-0.4	0.1	-1.7	-0.7	-1.5	-0.2	-0.7
Ovarian Cancer	0.7	0.9	1.9	0.3	0.8	-0.8	-1.4	-1.1	-1.4	0.1	-0.2	0.3	-1.4	-1.3
Body Mass Index (BMI) (2010)	0.7	0.9	2.4	1.5	1.0	1.1	0.9	1.0	0.7	1.3	0.0	0.0	0.9	0.9
Triglycerides	0.7	1.2	4.5	1.9	2.1	1.1	0.7	0.6	0.4	1.6	0.0	0.0	0.5	0.7
Angina	0.7	0.9	1.5	-1.1	-1.2	-0.8	-0.6	-0.8	-0.5	-1.1	-1.0	-1.2	-0.7	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	1.0	2.6	-1.6	-1.5	-0.4	0.4	0.4	0.7	-1.3	-0.8	-1.5	0.5	0.3
High blood pressure (mother)	0.7	0.9	1.9	1.0	1.2	-0.4	-1.0	-1.3	-1.4	1.1	-0.1	1.0	-1.0	-0.6
Body mass index (BMI)	0.7	2.8	7.1	-2.7	-2.3	-1.6	-1.2	-0.8	-0.9	-2.3	-1.1	-2.0	-1.2	-1.2
Number of incorrect matches in round	0.7	1.2	2.4	-1.5	-1.4	-0.9	-0.8	-1.0	-0.5	-1.4	-0.8	-1.5	-0.8	-1.0
Alcohol usually taken with meals	0.7	1.1	2.1	0.4	0.4	1.0	1.4	1.4	1.4	0.3	1.0	0.2	1.4	1.2
Weight	0.7	3.3	4.8	1.9	1.8	2.0	1.4	1.8	1.2	2.0	2.2	2.2	1.4	1.6
Noisy workplace	0.7	0.9	2.2	-0.4	-0.5	-0.7	-1.3	-1.2	-1.5	-0.4	-0.9	-0.4	-1.2	-0.9
Breast cancer (self-reported)	0.7	0.8	1.7	-1.3	-1.1	-0.9	-0.5	-0.5	-0.4	-1.2	-0.8	-1.2	-0.7	-0.7
Vascular/heart problems diagnosed by doctor	0.7	1.8	5.8	0.8	0.6	1.4	1.6	2.4	1.8	0.5	0.1	0.6	1.6	1.5
Alcohol drinker status: Previous	0.7	0.8	2.8	-1.3	-1.7	-0.4	-0.1	0.1	0.3	-1.4	0.2	-1.3	-0.0	-0.5
Schizophrenia vs Biploar Disorder	0.6	0.8	1.7	-0.1	0.3	-0.9	-1.2	-1.1	-1.3	-0.3	0.0	0.0	-1.3	-1.2
Worry (Nagel 2018)	0.6	1.2	3.4	-1.8	-1.6	-1.0	-0.3	-0.3	0.1	-1.8	-0.2	-1.5	-0.3	-0.5
Ulcerative Colitis (UC)	0.6	1.1	1.8	-1.0	-1.0	-1.0	-0.8	-0.7	-0.6	-1.3	-1.3	-1.3	-0.9	-1.3
Age at First Birth	0.6	0.9	2.3	0.3	0.4	-0.9	-1.4	-1.4	-1.5	0.2	0.0	0.0	-1.3	-1.2
Allergy or Eczema	0.6	1.6	4.9	0.3	-0.2	1.2	1.5	2.2	1.8	-0.1	1.5	0.1	1.6	0.9
Trunk fat percentage	0.6	2.3	5.1	-1.0	-1.1	1.1	1.9	2.1	2.3	-1.0	1.4	-0.8	1.9	1.3
Trunk fat mass	0.6	2.6	5.0	0.5	0.3	1.8	2.0	2.2	2.1	0.5	2.0	0.7	2.0	1.7
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.7	-1.3	-1.3	-0.5	0.1	0.0	0.4	-1.6	-1.1	-1.7	0.1	-0.1
Pain all over the body in last month	0.6	0.6	1.5	-0.6	-0.2	-0.9	-1.1	-1.1	-1.2	-0.1	-0.2	0.0	-1.1	-0.8
Medication: Ramipril	0.6	0.7	2.1	-0.2	0.0	-0.6	-1.1	-1.4	-1.3	-0.0	-0.1	-0.1	-1.1	-1.0
Pulse rate	0.6	1.0	2.3	-0.5	-0.1	-0.6	-1.3	-1.2	-1.5	-0.1	-1.2	-0.3	-1.3	-1.1
Happiness	0.6	0.7	1.5	-1.2	-1.1	-1.0	-0.5	-0.5	-0.3	-1.2	-0.3	-1.2	-0.5	-0.6
Exposure to tobacco smoke at home	0.6	0.7	2.3	0.3	0.5	0.5	0.9	0.7	0.9	0.5	1.5	0.8	0.9	1.1
Comparative body size at age 10	0.6	1.7	3.5	0.4	0.6	1.2	1.7	1.7	1.9	0.6	0.0	0.5	1.7	1.8
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.2	0.7	0.5	0.6	1.0	1.1	0.7	0.8	1.1	0.8	0.9	1.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.8	-1.3	-1.2	-0.4	-0.4	-0.5	-0.2	-1.3	-0.4	-1.2	-0.4	-0.6
Alcohol drinker status: Never	0.6	0.7	1.9	-1.3	-1.3	-0.4	-0.2	-0.2	0.0	-1.4	0.7	-1.2	-0.1	-0.5
Pain experienced in last month	0.6	1.0	2.2	0.7	0.8	-0.7	-1.1	-1.5	-1.5	0.9	-0.6	0.8	-1.1	-0.7
Basal cell carcinoma (self-reported)	0.6	0.8	2.1	1.5	0.9	0.9	0.3	0.6	0.1	1.1	1.3	1.1	0.3	0.1
Neuroticism (Nagel 2018)	0.5	1.2	3.3	-1.8	-1.5	-1.3	-0.7	-0.7	-0.4	-1.6	-0.3	-1.4	-0.6	-0.8
Number of treatments/medications taken	0.5	0.8	2.0	-1.4	-1.3	0.1	0.5	0.5	0.9	-1.4	0.8	-1.2	0.5	0.1
Hearing difficulty/problems with background noise	0.5	0.8	2.6	0.7	0.7	0.5	0.8	1.6	1.1	0.4	1.0	0.6	1.0	0.8
Qualifications: None of the above	0.5	1.0	3.1	-1.8	-1.5	-0.1	0.6	0.4	1.1	-1.4	0.3	-1.3	0.6	0.2
Neuroticism score	0.5	1.0	2.9	-1.6	-1.7	-1.0	-0.2	-0.2	0.2	-1.5	-0.5	-1.4	-0.1	-0.4
Arm fat percentage (right)	0.5	1.8	5.7	-2.4	-2.3	-0.6	-0.1	0.2	0.3	-2.2	-0.3	-1.9	-0.1	-0.4
Body fat percentage	0.5	1.9	3.9	-2.0	-2.0	0.2	1.0	1.3	1.5	-1.9	0.6	-1.6	1.0	0.5
Chest pain or discomfort	0.5	0.7	2.6	0.1	0.4	0.6	0.8	1.0	1.0	0.1	1.6	0.6	1.0	0.9
Arm fat percentage (left)	0.5	2.0	6.1	-2.5	-2.4	-0.7	-0.1	0.2	0.3	-2.3	-0.3	-2.1	-0.1	-0.4
Long-standing illness, disability or infirmity	0.5	0.7	1.6	-1.0	-0.8	0.4	0.7	0.8	0.9	-1.1	-0.8	-1.2	0.7	0.5
Ever taken oral contraceptive pill	0.5	0.5	1.2	-0.2	0.1	-0.6	-0.8	-0.6	-1.1	-0.5	-1.1	-0.5	-0.8	-0.8
Medication: Atorvastatin	0.5	0.6	0.9	0.6	0.9	1.0	0.8	0.6	0.7	0.8	0.6	0.7	0.9	0.8
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.2	0.9	0.9	1.5	1.1	1.3	1.1	0.8	0.8	0.7	1.1	0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.5	-1.0	-1.0	-0.8	-0.5	-0.4	-0.4	-1.2	0.0	0.0	-0.3	-0.5
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	1.4	-0.4	-0.2	0.7	0.9	1.2	1.1	-0.6	0.1	-0.5	1.0	0.6
Taking other prescription medications	0.4	0.7	1.4	-0.5	-0.8	0.6	1.0	1.0	1.2	-0.6	0.7	-0.5	1.0	0.8
High blood pressure	0.4	1.1	4.1	-0.6	-0.5	-1.0	-1.3	-2.0	-1.5	-0.3	0.1	-0.4	-1.2	-1.0
Hair/balding pattern: Pattern 2	0.4	0.5	1.1	1.1	0.6	1.0	0.6	0.8	0.7	0.9	-0.3	0.6	0.6	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	1.6	0.6	0.8	0.9	1.3	1.2	1.3	0.6	0.5	0.3	1.2	1.0
Fluid intelligence score	0.4	0.8	1.7	0.5	0.7	0.9	1.1	1.3	1.1	0.5	0.3	0.3	1.1	1.0
Time employed in main current job	0.4	0.4	0.8	0.8	0.6	0.6	0.7	0.7	0.5	0.9	0.1	0.7	0.7	0.7
Prospective memory result	0.4	0.5	0.9	0.9	1.0	0.4	-0.1	-0.5	-0.4	0.9	0.9	1.0	-0.2	-0.0
Angina (self-reported)	0.4	0.5	0.9	-0.8	-1.0	-0.5	-0.4	-0.6	-0.3	-0.8	-0.8	-1.0	-0.5	-0.8
Heart disease (mother)	0.4	0.5	1.6	-1.3	-0.7	-0.4	-0.4	-0.6	-0.2	-0.9	-0.5	-1.0	-0.5	-0.5
Had major operations	0.4	0.4	1.1	-1.0	-0.7	-0.6	-0.4	-0.5	-0.4	-0.9	-0.4	-0.9	-0.5	-0.3
Ever had bowel cancer screening	0.4	0.4	0.8	-0.5	-0.5	0.7	0.9	0.9	0.9	-0.4	-0.1	-0.6	0.8	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.0	0.8	0.5	-0.3	-0.7	-0.5	-0.9	0.4	-1.0	0.1	-0.7	-0.8
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.3	0.1	0.1	0.6	0.8	0.8	1.0	0.0	1.1	0.4	0.8	0.6
Medication: Bendroflumethiazide	0.4	0.7	1.9	1.1	1.1	0.3	-0.2	-0.6	-0.4	1.2	0.9	1.4	-0.3	0.1
Bipolar Disorder or Schizophrenia	0.3	0.7	1.4	-0.4	-1.0	-0.9	-0.9	-1.2	-1.0	-0.6	0.0	0.0	-0.8	-1.1
Neuroticism (2016)	0.3	0.5	1.6	-1.2	-1.1	-0.4	0.2	0.2	0.6	-1.3	-0.8	0.0	0.3	0.0
Ulcerative Colitis	0.3	0.4	0.7	-0.4	-0.7	-0.9	-0.8	-0.6	-0.6	-0.8	0.0	0.0	-0.8	-0.8
Blood Eosinophil Count	0.3	2.5	5.8	-1.3	-2.4	-1.9	-1.4	-1.2	-1.0	-1.9	-0.6	-1.6	-1.3	-1.9
Smoking Status	0.3	0.8	2.5	0.1	0.6	-0.5	-1.2	-1.6	-1.3	0.1	-0.0	0.2	-1.2	-0.9
Waist circumference	0.3	1.3	2.3	-1.4	-1.5	0.4	1.0	1.5	1.4	-1.3	-0.2	-1.2	0.9	0.5
Nervous feelings	0.3	0.5	1.6	-1.3	-1.2	-0.3	0.2	0.2	0.4	-1.1	0.3	-1.1	0.2	-0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	0.7	-0.6	-0.3	0.6	0.6	0.8	0.7	-0.4	0.8	-0.3	0.6	0.5
Worrier / anxious feelings	0.3	0.5	1.4	-1.2	-1.1	-0.5	-0.1	-0.4	0.2	-1.2	0.1	-1.0	0.0	-0.3
Hair/balding pattern: Pattern 3	0.3	0.5	1.0	-0.8	-0.6	-1.0	-0.7	-1.0	-0.7	-0.6	0.4	-0.4	-0.7	-0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.9	1.1	1.4	0.6	0.5	0.8	0.5	1.0	0.1	0.6	0.7	0.6
Breastfed as a baby	0.3	0.4	1.1	0.7	1.1	0.0	-0.4	-0.4	-0.8	0.9	-0.6	0.6	-0.5	-0.4
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.3	0.7	0.2	0.3	0.7	1.1	0.9	0.4	-0.5	0.5	0.8	0.8
Number of children fathered	0.3	0.3	0.5	-0.7	-0.7	-0.7	-0.5	-0.3	-0.4	-0.7	0.3	-0.6	-0.3	-0.5
Pulse wave peak to peak time	0.3	0.3	0.6	0.6	0.5	0.8	0.4	0.6	0.4	0.4	0.6	0.5	0.4	0.6
Shortness of breath walking on level ground	0.3	0.4	1.0	-0.3	-0.4	0.2	0.8	1.0	1.0	-0.2	0.0	-0.4	0.9	0.6
Qualifications: College or University degree	0.3	1.0	3.1	1.7	1.8	0.8	0.1	0.1	-0.3	1.4	0.6	1.2	0.1	0.2
Medication: Blood pressure	0.3	0.5	1.4	-0.9	-0.4	-0.3	-0.7	-1.2	-0.8	-0.6	0.8	-0.5	-0.8	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	0.4	0.6	0.6	0.6	0.5	0.6	0.4	0.6	0.5	0.5	0.6	0.4
Whole body fat mass	0.3	1.2	2.6	-0.2	-0.3	1.1	1.3	1.6	1.5	-0.1	1.4	0.1	1.3	1.1
Leg pain on walking	0.3	0.4	0.8	-0.2	-0.2	0.7	0.8	0.9	0.9	-0.0	0.4	-0.1	0.8	0.6
Illnesses of father: Heart disease	0.3	0.4	1.4	0.7	1.2	0.6	-0.3	-0.7	-0.6	0.7	0.3	0.9	-0.4	0.0
Average weekly red wine intake	0.3	0.4	0.8	0.8	0.7	0.6	0.3	0.7	0.1	0.8	0.8	0.9	0.2	0.5
Friendships satisfaction	0.3	0.4	1.2	-0.9	-0.9	-0.4	0.1	0.3	0.4	-1.0	-0.3	-1.1	0.2	0.0
Medication for cholesterol	0.3	0.4	0.9	0.7	0.9	0.8	0.4	0.7	0.3	0.6	0.6	0.8	0.3	0.6
Irritability	0.3	0.5	0.9	-0.9	-0.9	0.1	0.6	0.7	0.9	-0.8	0.2	-0.7	0.6	0.6
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.0	-0.1	0.1	-0.5	-0.6	-1.0	-0.8	-0.1	0.2	0.1	-0.8	-0.8
Heart disease (siblings)	0.3	0.3	1.1	-1.1	-0.3	-0.2	-0.0	-0.1	0.3	-0.9	-0.6	-1.0	-0.1	-0.2
Bipolar Disorder (2018)	0.2	0.3	0.9	1.0	0.6	0.4	0.4	0.0	0.2	0.9	0.0	0.0	0.4	0.4
Irritable Bowel Disease (IBD)	0.2	0.5	1.5	-0.4	-0.3	-0.6	-0.8	-0.7	-0.7	-0.7	-0.5	-0.6	-0.8	-1.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.2	1.0	1.1	0.7	0.3	0.5	0.2	0.9	0.3	0.7	0.3	0.2
Rheumatoid Arthritis	0.2	0.3	0.7	-0.3	-0.4	0.6	0.7	0.7	0.8	-0.3	0.0	0.0	0.5	0.4
Hair Pigment	0.2	6.8	9.2	-2.7	-2.1	-2.9	-3.0	-2.9	-3.0	-2.4	-1.0	-2.1	-3.0	-2.9
Serious illness, injury or assault to yourself	0.2	0.3	1.0	0.6	0.7	0.3	0.2	0.6	0.1	0.6	-1.0	0.2	0.2	0.3
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.2	-0.7	-1.0	-0.1	0.1	0.8	0.4	-1.1	0.1	-1.1	0.1	-0.5
Chronic bronchitis/emphysema (father)	0.2	0.2	0.5	-0.3	0.1	-0.3	-0.6	-0.4	-0.7	-0.3	-0.3	-0.2	-0.5	-0.6
Heart attack	0.2	0.3	0.8	0.1	0.2	-0.5	-0.6	-0.9	-0.8	0.1	0.3	0.3	-0.7	-0.7
Allergy	0.2	0.5	1.2	0.8	0.9	-0.2	-0.4	-1.1	-0.8	1.1	0.0	1.0	-0.4	0.2
Alcohol intake versus 10 years previously	0.2	0.3	2.0	-0.5	0.1	0.4	0.2	0.2	0.4	-0.2	-1.4	-0.6	0.2	0.1
Number of live births	0.2	0.3	0.7	0.7	0.5	0.0	-0.6	-0.7	-0.8	0.6	0.3	0.7	-0.6	-0.4
Depression (self-reported)	0.2	0.2	0.7	-0.3	-0.9	-0.1	0.4	0.7	0.6	-0.5	0.3	-0.2	0.5	0.3
Length of working week for main job	0.2	0.3	0.8	-0.9	-0.4	-0.4	-0.1	-0.1	-0.1	-0.6	-0.7	-0.9	-0.1	-0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.9	0.9	0.8	0.0	-0.0	0.1	-0.1	0.6	0.6	0.7	0.1	0.1
Worry too long after embarrassment	0.2	0.3	0.8	0.3	0.2	-0.7	-0.8	-0.6	-0.9	0.2	-0.6	0.0	-0.7	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.7	0.1	-0.1	-0.5	-0.8	-0.6	-0.8	-0.0	0.4	0.3	-0.7	-0.7
Age at first live birth	0.2	0.4	1.2	1.1	0.9	0.6	0.4	0.4	0.3	0.8	-0.4	0.5	0.5	0.6
Leg fat mass (right)	0.2	0.6	1.2	-1.1	-1.0	0.3	0.6	0.9	0.9	-0.9	0.7	-0.7	0.6	0.4
Number of full sisters	0.2	0.2	0.5	-0.1	-0.4	-0.5	-0.6	-0.4	-0.6	-0.1	-0.7	-0.1	-0.6	-0.7
Age at last live birth	0.2	0.2	1.2	0.7	0.8	0.2	-0.2	-0.2	-0.3	0.4	-1.1	0.0	-0.2	-0.0
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.8	-0.1	-0.3	0.1	-0.5	-0.8	-0.6	-0.2	-0.9	-0.3	-0.7	-0.5
Hypertension (Self-reported)	0.2	0.6	2.7	-0.2	0.0	-0.5	-1.0	-1.6	-1.2	0.2	0.5	0.1	-0.9	-0.7
Medication: Aspirin	0.2	0.2	0.8	-0.8	-0.4	-0.1	-0.1	-0.6	-0.1	-0.7	-0.2	-0.9	-0.1	-0.3
Illnesses of father: None of the above (group 1)	0.2	0.3	0.7	-0.2	-0.7	-0.8	-0.4	-0.3	-0.2	-0.5	-0.6	-0.5	-0.5	-0.7
Risk taking	0.2	0.2	0.9	-0.0	0.4	-0.1	-0.4	-0.4	-0.6	0.2	0.9	0.4	-0.5	-0.5
Age started oral contraceptive pill	0.2	0.2	0.7	-0.5	-0.7	-0.3	-0.3	-0.3	-0.3	-0.6	0.8	-0.3	-0.2	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.6	-0.1	0.3	0.8	0.6	0.7	0.8	0.1	0.1	-0.1	0.6	0.6
Leg fat mass (left)	0.2	0.7	1.2	-1.0	-0.9	0.4	0.8	1.1	1.0	-0.8	0.9	-0.5	0.7	0.6
Crohns Disease (2017)	0.1	0.2	0.7	0.2	0.2	-0.1	-0.5	-0.5	-0.5	-0.1	0.3	0.1	-0.5	-0.8
Reaction Time	0.1	0.1	0.6	0.4	0.3	-0.6	-0.3	-0.1	-0.3	0.2	-0.8	0.2	-0.4	-0.2
Prostate Cancer	0.1	0.1	0.3	-0.0	-0.3	0.3	0.2	0.6	0.4	-0.3	0.1	-0.0	0.3	0.2
HbA1C	0.1	0.1	0.2	0.0	-0.2	0.0	0.3	0.4	0.4	0.1	0.0	0.0	0.3	0.4
HDL Cholesterol	0.1	0.2	0.7	0.1	0.1	0.5	0.7	0.8	0.8	0.1	0.0	0.0	0.6	0.3
BMI	0.1	0.7	2.5	-1.6	-1.2	-0.9	-0.5	-0.1	-0.3	-1.2	-0.4	-1.0	-0.5	-0.3
Respiratory disease	0.1	0.3	0.8	-0.3	-0.9	-0.0	0.3	0.8	0.6	-0.7	0.3	-0.4	0.4	0.2
Sensitivity / hurt feelings	0.1	0.2	0.3	-0.4	-0.2	-0.2	-0.5	-0.6	-0.5	-0.4	0.2	-0.2	-0.4	-0.5
Relative age of first facial hair	0.1	0.1	0.4	0.5	0.4	0.7	0.2	0.4	0.1	0.2	-0.5	0.2	0.1	0.2
Systolic blood pressure, automated reading	0.1	0.4	1.2	-0.3	-0.7	0.6	0.9	0.3	1.1	-0.1	0.6	-0.4	0.9	0.6
Pack years adult smoking proportion	0.1	0.2	0.5	-0.1	-0.3	-0.1	-0.5	-0.6	-0.7	-0.0	-0.2	-0.2	-0.7	-0.6
Relative age voice broke	0.1	0.1	0.4	0.2	-0.0	0.1	-0.5	-0.5	-0.6	0.1	-0.5	-0.2	-0.5	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.5	0.4	0.7	0.6	0.6	0.5	0.5	0.6	0.5	0.4	0.5	0.5
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.3	0.3	0.2	0.3	-0.1	-0.1	-0.1	0.1	0.5	0.3	-0.1	-0.1
Asthma	0.1	0.2	0.9	-0.5	-0.9	-0.4	-0.2	0.3	0.1	-0.9	0.1	-0.5	-0.1	-0.4
Medication: Cholesterol lowering	0.1	0.1	0.4	-0.4	0.2	0.1	-0.1	-0.5	-0.3	-0.1	0.6	-0.2	-0.2	-0.2
Medication: Lansoprazole	0.1	0.1	0.1	0.3	0.1	0.4	0.4	0.2	0.4	0.0	-0.2	-0.1	0.3	0.1
Illnesses of mother	0.1	0.1	0.3	-0.0	-0.6	-0.1	0.3	0.6	0.4	-0.2	-0.5	-0.4	0.4	0.1
Arm fat mass (right)	0.1	0.5	1.3	-0.4	-0.4	0.7	0.8	1.1	0.9	-0.2	0.9	-0.0	0.8	0.7
Pulse wave reflection index	0.1	0.1	0.6	0.5	0.8	-0.0	0.2	-0.0	0.2	0.4	0.1	0.3	0.2	0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.4	-0.2	-0.4	-0.5	-0.1	0.3	-0.1	-0.4	-0.6	-0.4	0.1	-0.0
Blood clot in the leg (DVT)	0.1	0.2	0.6	-0.0	0.3	0.8	0.5	0.5	0.6	0.2	0.2	0.0	0.4	0.4
Exposure to tobacco smoke outside home	0.1	0.1	0.6	-0.8	-0.4	-0.3	-0.2	-0.2	-0.3	-0.4	0.1	-0.5	-0.2	0.0
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	-0.3	-0.6	0.2	0.3	0.7	0.6	-0.5	0.5	-0.2	0.4	0.1
Health satisfaction	0.1	0.1	0.3	-0.2	-0.4	-0.0	-0.4	-0.1	-0.4	-0.3	-0.2	-0.3	-0.4	-0.6
Medication for pain relief, constipation, heartburn	0.1	0.2	0.9	0.9	0.4	0.2	-0.1	-0.1	-0.3	0.8	-0.4	0.8	-0.1	-0.1
Mean time to correctly identify matches	0.1	0.2	0.5	0.7	0.5	0.0	0.4	0.4	0.3	0.6	-0.0	0.6	0.3	0.4
Medication: Aspirin	0.1	0.2	0.5	-0.6	-0.1	-0.1	-0.1	-0.6	-0.3	-0.4	-0.4	-0.7	-0.2	-0.3
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.8	0.4	0.9	0.4	0.2	0.2	0.1	0.7	-0.5	0.6	0.2	0.3
Asthma (self-reported)	0.1	0.1	0.4	-0.2	-0.7	-0.1	0.1	0.5	0.4	-0.6	0.4	-0.3	0.2	-0.1
Osteoporosis (self-reported)	0.1	0.1	0.3	-0.0	0.2	0.6	0.2	0.1	0.1	0.2	-0.5	-0.1	0.1	0.2
Arm fat mass (left)	0.1	0.4	0.7	-0.8	-0.7	0.5	0.6	0.8	0.7	-0.6	0.7	-0.4	0.5	0.4
Number of self-reported non-cancer illnesses	0.1	0.2	0.9	-0.5	-0.0	0.4	0.2	0.3	0.3	-0.4	0.9	-0.2	0.3	0.1
Commuting to job workplace: Public transport	0.1	0.1	0.4	0.5	0.6	0.0	0.1	0.2	-0.1	0.5	-0.0	0.4	0.0	0.1
Medication: Blood pressure	0.1	0.1	0.8	-0.1	-0.2	-0.3	-0.3	-0.9	-0.4	0.2	0.4	0.2	-0.2	-0.1
High cholesterol (Self-reported)	0.1	0.1	0.4	-0.6	-0.1	-0.1	0.4	0.4	0.5	-0.3	0.1	-0.4	0.5	0.2
Illnesses of father: High blood pressure	0.1	0.1	0.3	0.1	0.4	0.5	-0.1	-0.4	-0.2	0.1	0.3	-0.0	-0.2	-0.1
Number of operations (self-reported)	0.1	0.2	0.5	0.3	0.3	0.7	0.6	0.6	0.4	0.1	0.4	0.2	0.5	0.3
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.1	0.4	0.6	0.3	-0.2	-0.1	-0.1	-0.2	0.3	0.0	0.0	-0.0	-0.3
Primary Biliary Cirrhosis	0.0	0.0	0.2	-0.4	0.2	0.0	-0.0	-0.2	0.0	-0.1	0.0	0.0	-0.1	0.2
Systolic Blood Pressure	0.0	0.1	1.3	-0.2	-0.4	0.0	0.1	-1.1	0.1	-0.1	0.3	-0.2	0.0	0.1
Tanning	0.0	0.2	0.7	0.1	-0.1	0.2	0.4	0.9	0.4	-0.1	-0.4	-0.5	0.5	0.2
Eye problems/disorders: Diabetes related eye disease	0.0	0.0	0.1	-0.3	0.2	0.0	0.2	0.1	0.1	-0.0	0.4	-0.2	0.2	-0.1
Pulse wave Arterial Stiffness index	0.0	0.0	0.1	0.1	0.2	-0.3	-0.1	-0.3	-0.2	0.2	-0.2	0.0	-0.1	-0.2
Number of full brothers	0.0	0.0	0.2	0.2	0.4	-0.1	-0.1	0.2	-0.2	0.1	-0.3	0.1	-0.1	0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.1	0.0	-0.1	-0.0	-0.3	-0.3	-0.3	-0.1	-0.0	-0.1	-0.3	-0.2
Pulse rate, automated reading	0.0	0.1	0.3	-0.6	-0.3	0.2	-0.2	-0.2	-0.2	-0.2	-0.3	-0.2	-0.3	-0.0
Qualifications: nursing, teaching	0.0	0.0	0.1	0.1	0.2	0.1	-0.2	0.1	-0.2	-0.1	-0.1	-0.0	-0.2	-0.2
Pack years of smoking	0.0	0.0	0.1	0.1	-0.1	0.3	0.2	0.1	0.0	0.2	0.2	0.2	-0.0	0.0

Hub : Genes

NEIL1

Models

Trait associations