Best TWAS P=6.65e-12 · Best GWAS P=1.65e-17 conditioned to 4.68e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | AKAP13 | 0.23 | 0.06 | lasso | 6 | 0.05 | 9.0e-03 | -5.5 | 5.4 | 5.5e-08 | -0.41 | 0.30 | 0.10 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | RP11-815J21.2 | 0.20 | 0.09 | lasso | 5 | 0.08 | 1.8e-03 | -5.8 | 5.9 | 4.6e-09 | -0.45 | 0.17 | 0.17 | FALSE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | RP11-158M2.3 | 0.17 | 0.04 | lasso | 8 | 0.00 | 3.8e-01 | -5.5 | 5.5 | 4.1e-08 | -0.44 | 0.21 | 0.13 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AKAP13 | 0.08 | 0.03 | enet | 11 | 0.08 | 2.3e-08 | -6.3 | -6.9 | 6.7e-12 | 0.41 | 0.13 | 0.86 | TRUE |