Best TWAS P=7.59e-09 · Best GWAS P=1.94e-07 conditioned to 0.455
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | APOC1P1 | 0.05 | 0.03 | blup | 37 | 0.03 | 5.2e-04 | 2.2 | -5.5 | 5.1e-08 | 0.41 | 0.10 | 0.05 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | APOC2 | 0.27 | 0.25 | enet | 14 | 0.24 | 3.8e-14 | -5.0 | 5.2 | 2.7e-07 | -0.93 | 0.00 | 0.99 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | APOC4 | 0.06 | 0.03 | blup | 34 | 0.04 | 8.4e-06 | -5.0 | -5.8 | 7.6e-09 | 0.83 | 0.01 | 0.98 | TRUE |