TWAS hub - APOC2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.120	0.0410	1.2e-08	0.089	0.085	0.090	NA	0.099	6.0e-08	1.2e-07	4.8e-08	NA	9.2e-09
2	TCGA	Breast Invasive Carcinoma	0.176	0.0459	0.0e+00	0.199	0.140	0.250	NA	0.094	1.3e-39	1.7e-27	8.1e-51	NA	1.2e-18
3	TCGA	Colon Adenocarcinoma	0.129	0.0540	5.3e-05	0.047	0.058	0.056	NA	0.047	1.0e-03	2.9e-04	3.7e-04	NA	1.0e-03
4	TCGA	Head and Neck Squamous Cell Carcinoma	0.133	0.0427	0.0e+00	0.215	0.174	0.201	NA	0.207	1.0e-23	4.2e-19	4.2e-22	NA	8.6e-23
5	TCGA	Kidney Renal Clear Cell Carcinoma	0.189	0.0582	0.0e+00	0.272	0.209	0.228	NA	0.263	1.4e-30	4.5e-23	2.5e-25	NA	1.9e-29
6	TCGA	Kidney Renal Papillary Cell Carcinoma	0.266	0.0660	2.2e-16	0.248	0.219	0.244	NA	0.242	2.0e-14	1.1e-12	3.8e-14	NA	4.9e-14
7	TCGA	Lung Adenocarcinoma	0.238	0.0705	0.0e+00	0.244	0.245	0.267	NA	0.261	3.5e-28	2.3e-28	4.2e-31	NA	2.4e-30
8	TCGA	Lung Squamous Cell Carcinoma	0.157	0.0436	0.0e+00	0.273	0.246	0.266	NA	0.274	4.6e-31	1.0e-27	4.2e-30	NA	4.0e-31
9	TCGA	Ovarian Serous Cystadenocarcinoma	0.271	0.0740	5.6e-17	0.184	0.240	0.287	NA	0.262	1.6e-12	2.5e-16	1.1e-19	NA	7.8e-18
10	TCGA	Pancreatic Adenocarcinoma	0.178	0.0640	3.0e-06	0.121	0.125	0.128	NA	-0.001	9.5e-06	6.6e-06	5.2e-06	NA	3.5e-01
11	TCGA	Prostate Adenocarcinoma	0.202	0.0557	0.0e+00	0.242	0.139	0.271	NA	0.232	5.0e-25	2.5e-14	2.7e-28	NA	5.6e-24
12	TCGA	Soft Tissue Sarcoma	0.104	0.0460	2.3e-05	0.079	0.065	0.103	NA	0.091	2.1e-05	9.8e-05	1.0e-06	NA	4.8e-06
13	TCGA	Stomach Adenocarcinoma	0.081	0.0420	2.0e-04	0.068	0.031	0.032	NA	0.022	1.2e-05	2.7e-03	2.2e-03	NA	8.8e-03
14	TCGA	Testicular Germ Cell Tumors	0.144	0.0630	1.6e-04	0.147	0.148	0.157	NA	0.146	6.9e-06	6.8e-06	3.5e-06	NA	7.6e-06
15	TCGA	Thyroid Carcinoma	0.126	0.0410	5.0e-14	0.133	0.155	0.163	NA	0.165	7.1e-13	6.3e-15	1.3e-15	NA	8.7e-16
16	TCGA	Uterine Corpus Endometrial Carcinoma	0.199	0.0880	2.2e-04	0.144	0.083	0.144	NA	0.032	8.0e-05	2.5e-03	7.9e-05	NA	4.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Alzheimer’s Disease (including proxy)	19.2	27.9	187.7	-1.1	-1.7	1.0	-4.1	-3.5	-1.0	1.3	-3.8	-7.4	10.3	-2.6	-0.6	-2.6	-5.2	-2.4	-13.7
Triglycerides	10.5	17.2	72.4	-3.4	0.0	-2.5	-4.7	-4.6	-3.5	0.0	-4.7	-1.3	-3.7	-4.4	-4.0	-4.5	-4.7	-3.7	-8.5
LDL Cholesterol	9.2	14.5	84.1	4.5	0.0	3.8	2.7	3.0	4.1	0.0	3.0	2.0	9.2	4.0	4.7	3.6	1.9	3.6	-1.1
Alzheimer’s Disease (in mother)	8.5	10.0	77.8	1.5	1.4	2.4	-0.8	-0.2	1.6	2.8	-0.5	-2.3	8.8	0.4	2.0	0.5	-1.6	0.5	-6.9
HDL Cholesterol	6.1	10.3	20.3	-3.0	0.0	-2.8	-4.0	-3.9	-3.7	0.0	-3.9	-2.7	-4.5	-3.0	-2.4	-3.4	-3.9	-3.9	-1.5
Angina	5.8	7.6	14.4	2.6	2.5	1.5	2.9	3.1	2.7	3.5	3.0	1.5	3.8	3.1	3.2	3.2	2.5	2.4	1.3
Commuting to job workplace: Car/motor vehicle	5.5	6.2	7.4	2.6	2.6	1.7	2.5	2.4	2.5	2.6	2.5	2.5	2.6	2.7	2.6	2.6	2.5	2.6	2.4
Angina (self-reported)	5.4	7.1	13.0	2.4	2.3	1.4	2.9	3.1	2.6	3.4	3.0	1.4	3.6	3.0	3.1	3.1	2.5	2.4	1.3
Wears glasses or contact lenses	5.4	6.2	9.9	-3.1	-2.8	-2.7	-2.3	-2.3	-2.9	-1.5	-2.3	-2.9	-2.5	-2.2	-2.1	-2.4	-2.5	-2.7	-2.1
Serious illness, injury or assault to yourself	4.9	5.9	7.8	-2.1	-2.0	-2.8	-2.6	-2.5	-2.6	-2.1	-2.5	-2.3	-2.7	-2.1	-1.8	-2.3	-2.7	-2.7	-2.7
Medication: Simvastatin	4.5	6.7	37.0	2.2	2.2	4.1	1.7	1.8	2.6	2.6	1.7	1.3	6.1	1.8	2.1	2.0	1.4	2.2	0.5
Stomach or abdominal pain in last month	4.3	5.3	7.0	2.5	2.5	2.3	2.1	2.2	2.6	2.6	2.1	2.1	2.3	2.2	2.5	2.4	2.0	2.2	1.9
Medication: Omeprazole (e.g. Zanprol)	4.3	5.3	7.1	2.3	2.3	1.0	2.6	2.6	2.3	1.8	2.6	2.3	1.7	2.5	2.3	2.5	2.7	2.5	2.1
Allergy or Eczema	4.1	10.8	13.5	3.4	3.5	3.0	3.5	3.7	3.7	3.0	3.5	2.6	3.6	3.0	3.2	3.5	3.4	3.4	2.3
Exposure to tobacco smoke at home	4.1	4.6	8.0	-1.3	-1.6	-1.4	-2.5	-2.3	-1.9	-2.8	-2.4	-1.4	-2.1	-2.3	-1.7	-2.4	-2.5	-2.2	-2.6
Alzheimer’s Disease (in father)	3.9	4.2	30.0	-0.1	0.1	1.3	-0.9	-0.7	0.4	0.3	-0.8	-2.8	4.8	-0.9	-0.2	-0.5	-1.3	-0.1	-5.5
Blood Eosinophil Count	3.7	28.2	52.7	4.6	4.3	5.1	5.6	5.6	5.2	5.9	5.6	3.3	5.6	5.0	4.5	5.5	5.7	5.1	7.3
Relative age of first facial hair	3.6	7.3	9.3	2.5	2.7	1.6	3.0	3.1	2.8	2.4	3.0	2.8	2.3	2.9	2.8	3.0	2.9	2.8	2.1
Trunk fat-free mass	3.6	20.9	26.7	4.0	4.5	5.0	5.0	5.0	5.2	4.3	4.9	4.8	3.6	4.1	3.5	4.8	5.1	5.1	3.8
Lung cancer (father)	3.6	4.2	7.5	-2.1	-1.8	-2.6	-1.6	-1.8	-2.3	-2.7	-1.7	-1.8	-2.7	-1.8	-2.0	-2.0	-1.4	-1.9	-1.9
Trunk predicted mass	3.6	20.7	26.5	3.9	4.4	5.0	4.9	5.0	5.2	4.3	4.9	4.8	3.6	4.1	3.5	4.8	5.0	5.0	3.8
Forced expiratory volume in 1-second (FEV1), predicted	3.6	7.4	11.1	2.8	3.1	3.3	2.5	2.7	3.3	3.0	2.5	2.7	3.1	2.4	2.6	2.8	2.1	2.8	0.9
Ever had bowel cancer screening	3.5	4.0	6.2	2.2	2.1	1.4	2.0	2.0	2.0	1.8	2.0	2.5	1.4	2.2	2.1	2.2	2.1	1.9	1.9
Cholesterol lowering medication	3.5	5.1	37.7	1.9	1.6	3.4	1.3	1.5	2.1	2.2	1.3	0.2	6.1	1.3	1.8	1.6	0.7	1.5	-0.9
Schizophrenia (2014)	3.4	7.6	9.4	-2.4	-2.4	-2.5	-3.0	-3.0	-2.9	-2.9	-3.0	-2.3	-2.5	-2.8	-2.6	-3.1	-3.0	-2.7	-2.8
Medication: Omeprazole	3.4	4.1	5.7	2.1	2.2	1.4	2.2	2.2	2.2	1.4	2.2	2.4	1.6	2.0	2.0	2.0	2.2	2.3	1.6
Medication: Cholesterol lowering	3.3	5.1	32.5	2.2	2.3	3.2	1.1	1.2	2.2	2.0	1.2	1.1	5.7	1.6	2.2	1.6	0.8	1.8	-1.0
Whole body fat-free mass	3.3	18.6	24.0	3.6	4.1	4.9	4.8	4.8	4.9	4.1	4.7	4.5	3.2	3.8	3.2	4.5	4.8	4.8	3.7
Whole body water mass	3.1	17.9	23.7	3.6	4.0	4.9	4.6	4.7	4.8	4.0	4.6	4.4	3.1	3.7	3.2	4.4	4.7	4.7	3.6
Chronic bronchitis/emphysema (father)	3.0	3.5	6.6	1.6	2.1	1.1	1.7	1.8	1.7	2.1	1.8	2.6	1.1	2.1	2.0	1.9	1.8	1.9	2.1
Basal metabolic rate	3.0	16.7	21.8	3.3	3.8	4.7	4.6	4.7	4.7	3.8	4.5	4.3	2.7	3.6	2.9	4.3	4.6	4.5	3.6
Leg fat-free mass (right)	2.9	15.3	22.0	3.2	3.5	4.7	4.4	4.5	4.5	3.7	4.3	3.9	2.8	3.3	2.8	4.1	4.3	4.3	3.4
Arm predicted mass (left)	2.9	14.6	19.4	3.2	3.6	4.3	4.3	4.3	4.3	3.4	4.2	4.2	2.5	3.4	2.8	4.0	4.4	4.3	3.4
Breast Cancer	2.8	6.8	10.8	3.0	3.1	1.8	2.3	2.3	2.7	2.7	2.4	3.0	3.3	2.9	2.9	2.6	2.2	2.7	1.3
Illnesses of father: Heart disease	2.8	3.9	11.4	1.8	1.5	2.9	1.8	1.8	2.2	1.9	1.7	1.3	3.4	1.4	1.4	1.7	1.9	2.0	2.1
Leg predicted mass (right)	2.8	15.0	21.8	3.1	3.5	4.7	4.3	4.4	4.5	3.7	4.3	3.8	2.8	3.3	2.8	4.1	4.3	4.2	3.4
High cholesterol (Self-reported)	2.8	4.9	45.0	1.4	1.2	2.8	-0.3	-0.1	1.2	0.8	-0.2	-0.7	6.7	0.2	1.3	0.3	-1.0	0.4	-4.0
Arm fat-free mass (left)	2.8	14.4	18.6	3.2	3.6	4.3	4.2	4.2	4.3	3.4	4.1	4.2	2.4	3.4	2.8	4.0	4.3	4.2	3.3
Ever had hysterectomy (womb removed)	2.7	3.1	4.1	-1.7	-1.5	-1.4	-1.9	-2.0	-2.0	-1.9	-1.9	-1.2	-1.8	-1.8	-1.9	-2.0	-1.8	-1.6	-1.5
Standing height	2.7	27.3	34.2	4.9	5.3	5.0	5.5	5.7	5.8	5.2	5.5	5.3	4.8	5.0	4.6	5.5	5.5	5.7	3.7
Heart attack/myocardial infarction (self-reported)	2.7	3.5	8.9	1.9	1.8	1.9	1.7	2.0	2.1	2.0	1.8	1.1	3.0	1.7	2.2	2.0	1.5	1.6	0.2
Leg fat-free mass (left)	2.6	13.6	19.3	2.9	3.3	4.4	4.2	4.3	4.3	3.6	4.2	3.5	2.5	3.1	2.6	3.9	4.2	4.0	3.3
Relative age voice broke	2.6	4.0	6.3	1.5	1.5	0.8	2.5	2.5	1.9	2.5	2.5	1.0	1.6	2.3	2.0	2.5	2.2	1.9	1.5
Leg predicted mass (left)	2.6	13.5	19.1	2.8	3.2	4.4	4.2	4.3	4.3	3.6	4.2	3.5	2.4	3.1	2.5	3.9	4.2	4.0	3.3
Number of children fathered	2.6	2.9	4.6	1.3	1.8	1.1	1.7	1.5	1.4	2.1	1.7	1.9	1.7	1.9	1.5	1.6	1.8	1.9	2.0
Hand grip strength (left)	2.5	6.6	8.2	2.6	2.6	2.5	2.5	2.7	2.9	2.2	2.6	2.9	2.7	2.6	2.7	2.8	2.4	2.5	1.4
Supplements: Fish oil (including cod liver oil)	2.5	3.3	5.8	-1.0	-1.1	-1.7	-2.4	-2.4	-1.9	-1.8	-2.3	-0.8	-1.4	-1.6	-1.1	-2.1	-2.4	-1.9	-2.0
Arm fat-free mass (right)	2.4	12.2	17.7	2.9	3.3	4.2	3.8	3.8	4.0	3.2	3.7	4.0	2.3	3.0	2.5	3.6	3.9	3.9	3.1
Comparative height size at age 10	2.4	12.9	15.9	3.5	3.9	2.6	3.9	3.9	3.8	3.4	3.9	3.7	3.0	3.7	3.3	3.9	4.0	3.9	2.6
Eye problems/disorders: Cataract	2.4	2.7	4.8	1.9	2.1	1.1	1.4	1.4	1.7	1.4	1.5	2.2	1.5	1.8	1.9	1.6	1.5	1.8	1.2
Tinnitus: Yes, now most or all of the time	2.4	2.8	7.8	1.9	1.6	2.8	1.5	1.5	2.1	0.9	1.4	1.9	1.6	1.1	1.0	1.5	1.7	1.8	1.3
Bipolar Disorder or Schizophrenia	2.2	5.4	8.6	-1.7	-1.4	-2.4	-2.8	-2.7	-2.4	-2.3	-2.7	-1.3	-2.2	-2.0	-1.3	-2.4	-2.9	-2.6	-2.9
Schizophrenia vs Biploar Disorder	2.2	2.9	7.3	-2.1	0.0	-0.8	-1.6	-1.9	-1.7	-2.0	-1.8	-1.8	-1.2	-2.2	-2.7	-2.3	-1.3	-1.0	-0.3
Tense / ‘highly strung’	2.2	3.6	6.1	-1.2	-1.4	-1.6	-2.4	-2.5	-2.0	-2.1	-2.4	-1.0	-1.3	-1.9	-1.6	-2.4	-2.2	-1.8	-1.8
Worry (Nagel 2018)	2.1	4.5	6.9	-1.6	-1.9	-2.6	-2.2	-2.3	-2.3	-2.0	-2.2	-2.4	-1.7	-1.9	-1.7	-2.3	-2.2	-2.2	-2.0
Birth weight	2.1	4.6	6.8	2.2	2.6	1.2	2.2	2.3	2.2	1.8	2.3	2.5	1.7	2.4	2.4	2.4	2.0	2.1	0.7
Health satisfaction	2.1	2.8	6.6	-1.1	-1.0	-2.1	-1.9	-1.8	-1.7	-1.3	-1.8	-1.0	-1.8	-1.1	-0.5	-1.4	-2.2	-1.9	-2.6
Heart attack	2.0	2.5	6.9	1.5	1.4	1.7	1.5	1.7	1.8	1.8	1.5	0.8	2.6	1.5	1.9	1.8	1.3	1.3	0.0
Worrier / anxious feelings	2.0	3.7	11.0	-1.3	-1.1	-3.3	-2.2	-2.3	-2.3	-1.2	-2.1	-1.7	-1.6	-1.1	-0.6	-1.8	-2.3	-2.1	-2.2
Illnesses of father: None of the above (group 1)	2.0	2.5	9.8	-1.4	-1.2	-2.4	-1.2	-1.1	-1.7	-1.8	-1.2	-0.9	-3.1	-1.2	-1.0	-1.2	-1.3	-1.7	-1.5
Age at First Birth	1.9	2.7	4.1	-1.5	-1.5	-0.5	-2.0	-1.9	-1.5	-1.5	-2.0	-1.4	-1.3	-1.9	-1.4	-1.8	-2.0	-1.9	-1.3
Height	1.9	37.3	50.3	5.6	6.1	5.7	6.9	7.1	7.1	5.6	6.9	6.0	5.2	5.8	5.4	6.7	6.7	6.7	3.4
Weight	1.9	9.4	14.8	2.2	2.5	3.4	3.8	3.9	3.5	2.7	3.7	3.1	1.2	2.5	1.9	3.3	3.8	3.4	2.9
Illnesses of mother	1.9	2.4	8.0	1.5	1.4	0.7	1.6	1.5	1.4	0.9	1.6	1.9	-0.3	1.5	1.3	1.5	1.9	1.4	2.8
Shortness of breath walking on level ground	1.9	2.2	4.4	-1.5	-1.6	-1.9	-1.4	-1.5	-1.9	-1.4	-1.4	-1.4	-2.1	-1.1	-1.2	-1.5	-1.2	-1.6	-0.1
Arm predicted mass (right)	1.9	9.6	14.6	2.5	2.9	3.8	3.4	3.4	3.5	2.8	3.3	3.6	2.0	2.6	2.1	3.2	3.5	3.5	2.7
Schizophrenia (2018)	1.7	3.4	4.9	-1.6	-1.4	-1.7	-2.1	-2.1	-1.9	-2.0	-2.1	-1.2	-1.6	-1.8	-1.5	-2.1	-2.2	-1.8	-2.1
Ovarian Cancer	1.7	2.3	4.8	-1.1	-1.3	1.0	-1.7	-1.6	-0.9	-2.1	-1.7	-0.6	-1.1	-2.2	-1.8	-1.8	-1.7	-1.2	-1.2
Hayfever, allergic rhinitis or eczema	1.7	3.6	5.1	2.1	2.2	1.1	2.1	2.2	2.1	1.5	2.2	1.2	2.0	1.9	2.1	2.1	2.0	1.9	1.0
Number of live births	1.7	2.3	3.6	1.7	1.6	1.7	1.6	1.7	1.9	1.5	1.6	1.3	1.3	1.3	1.4	1.6	1.4	1.5	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.5	9.3	2.5	2.9	1.4	2.1	2.3	2.5	2.5	2.3	2.0	2.9	2.7	3.1	2.7	1.7	2.0	-0.1
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	4.8	1.8	1.9	2.1	1.9	2.0	2.2	1.4	1.9	1.8	2.0	1.3	1.3	1.7	2.1	2.0	1.4
Exposure to tobacco smoke outside home	1.7	2.3	2.9	1.6	1.5	1.0	1.5	1.5	1.5	1.7	1.5	1.7	1.6	1.6	1.6	1.5	1.5	1.4	1.6
Illnesses of father: High blood pressure	1.7	2.1	5.8	1.2	1.3	1.9	1.2	1.0	1.3	1.2	1.1	1.9	1.6	1.2	0.6	1.0	1.5	1.8	2.4
Systolic Blood Pressure	1.6	8.0	14.0	-2.4	-2.4	-1.0	-3.6	-3.7	-2.9	-2.6	-3.6	-2.2	-0.4	-2.9	-2.6	-3.5	-3.7	-2.6	-2.7
Forced expiratory volume in 1-second (FEV1)	1.6	5.3	8.1	2.5	2.8	1.3	2.2	2.4	2.5	2.2	2.3	2.2	2.6	2.6	2.8	2.7	1.9	2.2	-0.1
Mouth/teeth dental problems: Loose teeth	1.6	1.9	4.7	0.6	0.9	-0.2	1.5	1.4	0.8	2.1	1.5	0.8	0.8	1.8	1.4	1.6	1.7	1.1	2.2
Heart disease (siblings)	1.6	2.0	2.9	1.1	0.9	1.5	1.6	1.6	1.5	1.2	1.6	1.3	1.6	1.3	0.8	1.4	1.7	1.7	1.3
Townsend deprivation index at recruitment	1.5	2.1	4.5	1.6	1.4	0.3	1.5	1.4	1.2	1.4	1.5	1.4	0.9	1.6	1.6	1.4	1.7	1.3	2.1
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	2.5	-1.6	-1.2	-1.5	-1.3	-1.4	-1.5	-1.4	-1.3	-0.7	-1.4	-1.1	-1.2	-1.4	-1.2	-1.3	-1.3
Breast cancer (self-reported)	1.5	1.8	3.7	-0.9	-1.3	-0.6	-1.4	-1.2	-1.1	-1.8	-1.4	-1.5	-1.3	-1.5	-1.1	-1.2	-1.4	-1.6	-1.9
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	3.4	-0.9	-1.1	-1.0	-1.3	-1.3	-1.2	-1.8	-1.3	-0.7	-1.4	-1.4	-1.3	-1.4	-1.2	-1.3	-1.1
Hand grip strength (right)	1.4	3.9	6.2	1.8	2.2	2.3	1.9	1.9	2.2	1.4	1.9	2.5	2.3	1.9	1.9	2.0	1.8	2.1	0.6
Sitting height	1.4	9.7	13.2	2.5	2.8	3.4	3.4	3.5	3.5	3.6	3.4	2.2	3.2	2.9	2.5	3.5	3.5	3.2	2.4
Fluid intelligence score	1.4	2.9	5.6	1.1	1.3	1.4	1.8	1.7	1.5	2.1	1.8	1.6	2.0	1.7	1.3	1.6	1.8	2.0	2.4
Forced vital capacity (FVC), Best measure	1.4	5.2	8.0	2.4	2.7	1.5	2.1	2.3	2.4	2.6	2.2	1.8	2.8	2.6	2.8	2.7	1.8	2.0	-0.1
Pain type(s) experienced in last month: Hip pain	1.4	1.8	5.4	1.8	1.6	2.3	1.1	1.2	1.8	1.0	1.0	1.7	1.2	0.7	0.9	0.9	0.9	1.4	0.9
Bipolar Disorder (2018)	1.3	2.0	3.5	-0.8	-0.6	-1.8	-1.8	-1.6	-1.5	-1.1	-1.6	-0.4	-1.7	-0.9	-0.3	-1.2	-1.9	-1.9	-1.8
Had major operations	1.3	1.5	2.8	-0.7	-1.1	0.1	-1.5	-1.5	-0.9	-1.2	-1.6	-1.2	-1.0	-1.7	-1.3	-1.4	-1.4	-1.3	-0.9
Family relationship satisfaction	1.3	1.6	3.3	0.9	1.1	0.1	1.3	1.2	1.0	1.8	1.3	1.0	0.9	1.7	1.5	1.6	1.4	1.2	1.0
Friendships satisfaction	1.3	1.6	5.3	1.1	1.2	-0.8	1.1	1.2	0.8	2.0	1.2	0.3	1.1	2.0	2.3	1.6	0.7	0.6	0.2
Average weekly champagne plus white wine intake	1.3	1.8	2.9	-1.5	-1.2	-0.4	-1.3	-1.4	-1.2	-1.4	-1.4	-0.9	-1.1	-1.6	-1.7	-1.6	-1.5	-1.1	-1.6
Alcohol drinker status: Previous	1.3	1.5	3.7	-1.0	-0.8	-1.6	-1.2	-1.1	-1.3	-1.2	-1.1	-1.2	-1.1	-0.9	-0.7	-1.1	-1.3	-1.2	-1.9
Hypothyroidism (self reported)	1.2	2.8	5.2	1.3	1.3	1.9	2.0	2.0	1.9	1.3	1.9	1.1	1.9	1.1	0.8	1.5	2.3	1.9	1.9
Birth weight of first child	1.2	2.1	3.2	1.6	1.7	1.0	1.4	1.4	1.6	1.5	1.4	1.2	1.8	1.4	1.4	1.4	1.4	1.6	1.3
Smoking status: Previous	1.2	1.8	3.0	1.2	1.0	1.1	1.6	1.7	1.6	1.4	1.6	0.8	1.4	1.3	1.4	1.7	1.5	1.1	1.0
Long-standing illness, disability or infirmity	1.2	1.8	3.6	-1.6	-1.6	-0.1	-1.0	-1.0	-1.1	-1.8	-1.1	-1.5	-1.7	-1.8	-1.9	-1.3	-0.8	-1.3	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.6	5.2	2.0	2.2	0.8	1.3	1.5	1.6	1.4	1.5	1.6	1.9	2.0	2.3	1.8	0.9	1.3	-0.2
Sensitivity / hurt feelings	1.1	1.9	3.6	-1.3	-1.3	-1.1	-1.4	-1.4	-1.4	-1.1	-1.4	-1.6	-1.9	-1.4	-1.2	-1.3	-1.5	-1.6	-1.1
Age when periods started (menarche)	1.1	2.5	4.6	1.0	1.1	0.3	2.1	2.0	1.3	1.7	2.1	0.7	0.6	1.9	1.2	2.0	2.1	1.6	2.1
Past tobacco smoking	1.1	2.0	3.3	-1.1	-1.0	-1.2	-1.6	-1.8	-1.6	-1.5	-1.7	-0.7	-1.2	-1.3	-1.4	-1.8	-1.6	-1.1	-1.4
Forced vital capacity (FVC)	1.1	4.3	6.6	2.2	2.6	1.1	2.0	2.1	2.3	2.0	2.1	1.8	2.4	2.4	2.5	2.4	1.7	2.0	-0.5
Loud music exposure frequency	1.1	1.2	2.5	-0.8	-0.9	-1.6	-1.4	-1.5	-1.5	-0.3	-1.3	-1.3	-0.5	-0.6	-0.5	-1.2	-1.1	-1.2	-0.2
Pulse rate, automated reading	1.1	3.5	11.9	-1.7	-1.6	-2.2	-1.8	-1.9	-2.0	-2.6	-1.8	-0.4	-3.4	-1.6	-1.7	-1.8	-1.4	-1.7	-0.6
Waist Hip Ratio (WHR)	1.0	4.6	8.8	-2.1	-2.3	-2.1	-2.2	-2.2	-2.5	-2.0	-2.2	-1.4	-3.0	-2.0	-1.8	-2.3	-2.2	-2.4	-0.6
Ever used hormone-replacement therapy (HRT)	1.0	1.3	3.9	-0.8	-0.6	-1.7	-1.1	-1.0	-1.2	-1.5	-1.0	-0.3	-2.0	-0.8	-0.5	-1.0	-1.0	-1.2	-1.3
Hip circumference	1.0	4.4	8.5	1.0	1.3	2.7	2.9	2.9	2.5	1.8	2.7	1.7	0.5	1.4	0.6	2.2	2.8	2.4	1.7
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	3.2	0.3	0.3	-0.4	1.4	1.3	0.5	1.5	1.4	0.4	0.4	1.4	0.9	1.3	1.6	0.9	1.8
Gout (self-reported)	1.0	1.4	2.4	1.3	1.3	0.6	1.4	1.5	1.3	1.0	1.4	0.6	0.9	1.2	1.5	1.4	1.1	1.0	0.2
Mean Putamen Volume	0.9	1.0	1.7	1.0	0.8	0.8	1.1	1.2	1.0	1.3	1.1	0.2	0.6	1.0	0.9	1.3	1.2	0.8	1.3
HbA1C	0.9	1.0	2.2	1.3	1.3	0.6	0.4	0.3	0.9	0.8	0.5	1.1	0.9	1.3	1.0	1.0	1.1	1.3	1.5
Chronotype (morning person)	0.9	2.0	4.5	1.8	1.8	0.7	1.0	1.2	1.4	1.4	1.2	1.4	1.9	1.7	2.1	1.6	0.9	1.1	0.2
Diabetes (father)	0.9	1.1	4.2	-1.0	-1.3	-2.0	-0.5	-0.6	-1.2	-0.6	-0.5	-1.2	-2.0	-0.6	-0.8	-0.7	-0.5	-1.0	0.3
Trunk fat mass	0.9	3.7	6.4	1.2	1.4	1.6	2.5	2.5	2.1	1.7	2.4	2.1	-0.0	1.6	1.1	2.1	2.5	2.1	2.1
Ever had prostate specific antigen (PSA) test	0.9	1.0	2.1	-1.2	-1.1	-1.5	-1.0	-0.9	-1.2	-0.5	-0.9	-1.0	-1.4	-0.6	-0.6	-0.8	-1.0	-1.2	-0.6
Prostate Cancer	0.8	1.2	2.9	-0.8	-0.7	-0.8	-1.3	-1.4	-1.0	-1.7	-1.3	-0.3	-1.1	-1.1	-0.9	-1.3	-1.0	-1.0	-0.8
Blood Platelet Count	0.8	9.7	24.3	-2.8	-2.5	-2.9	-3.6	-3.7	-3.4	-2.5	-3.5	-1.0	-4.9	-2.9	-2.6	-3.6	-3.5	-3.0	-1.4
Cardiovascular Disease	0.8	2.6	8.0	-1.1	-0.9	-0.0	-1.9	-1.8	-1.3	-0.9	-1.8	-1.8	2.4	-1.2	-0.7	-1.6	-2.1	-1.3	-2.8
Multivitamins +/- minerals	0.8	1.0	1.9	-0.3	-0.3	-0.5	-1.4	-1.3	-0.8	-1.2	-1.3	-0.3	-1.0	-1.0	-0.4	-1.2	-1.4	-1.1	-1.2
Noisy workplace	0.8	1.0	2.2	-1.5	-1.4	-1.2	-0.4	-0.6	-1.1	-1.0	-0.5	-1.0	-1.5	-0.9	-1.4	-1.0	-0.3	-0.7	-0.4
Medication: Blood pressure	0.8	1.5	2.8	-1.1	-1.0	-0.2	-1.7	-1.6	-1.1	-1.3	-1.6	-0.8	-0.7	-1.4	-1.0	-1.4	-1.5	-1.2	-1.0
Ever taken oral contraceptive pill	0.8	0.9	1.2	0.7	1.0	0.4	1.0	1.0	0.8	1.1	1.0	1.1	0.7	1.1	0.9	1.0	0.9	1.0	1.1
Myopia	0.8	1.1	2.3	-1.3	-1.5	-0.1	-1.1	-1.0	-1.0	-0.4	-1.1	-1.3	-1.3	-1.1	-1.0	-0.9	-1.1	-1.2	-0.1
Leg fat mass (left)	0.8	3.0	5.2	1.0	1.2	1.8	2.2	2.3	1.9	1.3	2.2	2.0	-0.2	1.3	0.9	1.9	2.2	1.8	2.0
Intelligence (Savage-Jansen 2018)	0.7	2.1	6.1	0.9	0.7	0.8	1.5	1.4	1.1	2.0	1.4	1.5	1.3	1.5	1.1	1.4	1.4	1.4	2.5
Body Mass Index (BMI) (2010)	0.7	1.0	2.0	-1.4	0.0	0.0	-1.0	-1.1	-1.4	0.0	-1.1	-1.4	0.0	-1.2	-1.3	-1.2	-1.0	-1.2	0.0
Rheumatoid Arthritis	0.7	0.9	4.0	0.6	0.7	2.0	0.5	0.4	0.8	0.8	0.5	0.8	1.3	0.5	0.3	0.4	0.8	0.8	2.0
Blood White Count	0.7	5.1	11.9	-2.1	-2.3	-3.5	-2.3	-2.3	-3.0	-0.3	-2.2	-2.7	-2.7	-1.3	-1.1	-2.0	-2.4	-2.7	-0.1
Type 2 Diabetes (T2D) (2018)	0.7	1.3	3.1	-1.8	-1.3	-0.6	-1.0	-1.1	-1.3	-0.7	-1.1	-0.7	-1.7	-1.1	-1.3	-1.2	-1.0	-1.1	0.2
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.8	-1.0	-0.9	-0.0	-1.0	-0.9	-0.8	-1.3	-1.0	-1.1	-0.9	-1.3	-1.2	-1.1	-0.8	-1.0	-0.3
Supplements: Zinc	0.7	0.7	1.4	1.2	1.0	0.6	0.8	0.8	1.0	0.6	0.8	0.9	1.0	0.8	1.1	0.8	0.8	0.9	0.6
Pack years adult smoking proportion	0.7	1.0	3.8	-0.5	-0.4	-2.0	-1.1	-1.1	-1.2	-1.2	-1.0	-0.2	-1.2	-0.5	-0.3	-0.9	-1.1	-1.1	-1.0
Current tobacco smoking	0.7	1.2	2.0	-1.2	-1.1	-0.3	-1.4	-1.4	-1.1	-0.7	-1.4	-0.4	-1.4	-1.2	-1.1	-1.3	-1.1	-1.1	-0.1
Maternal smoking around birth	0.7	1.0	1.8	1.3	1.2	0.8	0.9	1.0	1.2	1.1	0.9	1.2	1.0	1.1	1.4	1.1	0.7	0.9	0.3
Allergy	0.7	1.6	2.4	-1.3	-1.4	-0.4	-1.5	-1.6	-1.3	-1.1	-1.5	-0.6	-1.0	-1.3	-1.5	-1.4	-1.5	-1.2	-0.8
Falls in the last year	0.7	0.9	2.4	-1.3	-1.2	-1.6	-0.6	-0.7	-1.1	-0.7	-0.6	-0.9	-1.0	-0.7	-0.9	-0.8	-0.7	-0.8	-1.2
Pulse rate	0.7	1.2	5.2	-1.2	-1.3	-1.3	-0.6	-0.7	-1.1	-1.4	-0.7	-0.6	-2.3	-0.8	-1.1	-0.8	-0.4	-1.1	0.1
Mouth/teeth dental problems: Dentures	0.7	1.3	2.3	-1.2	-1.3	-1.4	-0.9	-0.8	-1.1	-1.0	-0.9	-1.2	-1.5	-1.0	-0.8	-0.8	-0.9	-1.4	-1.2
Medication: Lansoprazole	0.7	0.8	2.4	0.8	0.7	-0.5	0.6	0.6	0.3	1.2	0.7	0.6	0.3	1.3	1.4	1.0	0.7	0.3	1.5
Medication: Paracetamol	0.7	1.2	2.3	-1.1	-1.2	-1.0	-1.0	-1.0	-1.1	-1.3	-1.0	-0.8	-1.5	-1.2	-1.1	-1.2	-0.9	-1.1	-0.6
Comparative body size at age 10	0.7	1.8	5.8	1.2	1.4	2.4	1.1	1.3	1.8	1.3	1.2	1.2	1.7	0.9	1.2	1.4	1.0	1.3	0.4
Chest pain or discomfort	0.7	1.0	2.0	0.9	0.8	0.4	1.3	1.4	1.1	1.2	1.3	-0.0	0.9	1.0	1.1	1.3	1.1	0.8	0.2
Medication: Aspirin	0.7	0.9	3.7	1.2	1.1	1.0	0.5	0.6	0.9	0.9	0.6	0.8	1.9	1.0	1.5	0.9	0.3	0.6	0.0
Loneliness, isolation	0.7	0.9	1.5	1.1	1.2	0.8	0.9	0.9	1.0	1.2	0.9	0.9	1.0	0.9	1.1	0.9	0.8	0.9	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	1.4	1.0	1.0	1.1	0.8	0.8	1.1	1.0	0.8	0.9	1.2	0.7	0.7	0.8	0.6	1.0	0.1
Medication: Atorvastatin	0.7	0.9	8.4	0.4	0.0	0.2	0.0	0.1	0.2	0.3	0.1	-0.9	2.9	0.2	0.6	0.2	-0.3	0.0	-2.0
Frequency of depressed mood in last 2 weeks	0.6	0.8	4.3	-0.3	-0.4	-0.6	-1.0	-0.8	-0.6	-0.8	-0.9	-0.7	-0.7	-0.8	-0.2	-0.8	-1.3	-1.0	-2.1
Nervous feelings	0.6	1.2	2.0	-0.8	-0.9	-1.2	-1.1	-1.2	-1.1	-1.4	-1.1	-1.0	-0.7	-1.2	-1.2	-1.4	-0.9	-0.7	-1.2
Had other major operations	0.6	0.8	2.8	-0.6	-1.1	-0.2	-0.4	-0.3	-0.5	-1.7	-0.5	-1.0	-1.2	-1.3	-1.2	-0.8	-0.3	-0.8	-0.4
Qualifications: None of the above	0.6	1.2	3.6	1.8	1.6	-0.3	0.5	0.6	0.8	0.9	0.7	1.7	0.6	1.5	1.9	1.0	0.5	0.6	0.3
Arm fat mass (right)	0.6	2.5	4.9	0.7	0.9	1.6	2.2	2.2	1.7	1.1	2.1	1.5	-0.4	1.1	0.5	1.7	2.1	1.7	1.8
Hair/balding pattern: Pattern 4	0.6	1.4	2.0	1.0	1.3	0.6	1.2	1.2	1.1	1.3	1.2	1.2	1.1	1.4	1.1	1.3	1.3	1.2	1.4
Pulse wave peak to peak time	0.6	0.7	2.6	0.5	0.6	0.3	0.9	0.6	0.5	0.7	0.8	0.4	1.6	0.7	0.1	0.6	1.2	1.1	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.2	0.7	0.8	1.0	0.9	1.0	1.0	0.6	0.9	1.1	0.7	0.6	0.9	0.8	0.7	0.8	0.9
Whole body fat mass	0.6	2.6	4.8	0.8	1.1	1.4	2.2	2.2	1.7	1.2	2.1	1.9	-0.4	1.2	0.8	1.7	2.1	1.7	1.7
Leg fat mass (right)	0.6	2.4	4.5	0.8	1.0	1.6	2.1	2.1	1.7	1.2	2.0	1.7	-0.4	1.1	0.7	1.7	2.1	1.6	1.7
Back pain experienced in last month	0.6	0.9	3.0	1.2	1.1	1.6	0.6	0.8	1.2	0.4	0.7	1.7	-0.2	0.5	1.0	0.7	0.3	0.7	0.2
Medication: Aspirin	0.6	0.8	3.7	1.1	1.1	1.1	0.5	0.6	0.9	0.9	0.6	0.6	1.9	0.8	1.3	0.9	0.3	0.5	-0.2
Smoking status: Current	0.6	1.0	1.7	-1.0	-1.0	-0.2	-1.3	-1.3	-1.0	-0.5	-1.3	-0.6	-1.1	-1.2	-1.0	-1.1	-1.1	-1.0	0.0
Irritability	0.6	1.1	3.1	1.7	1.7	0.3	0.6	0.8	1.1	1.2	0.7	0.9	0.9	1.1	1.8	1.0	0.3	0.6	-0.1
Lung FEV1/FVC ratio	0.5	2.4	5.8	1.9	1.9	0.6	1.3	1.6	1.5	1.8	1.5	1.4	1.2	2.0	2.4	2.0	1.0	1.0	0.6
Impedance of leg (right)	0.5	2.3	8.0	-1.0	-1.1	-2.8	-1.6	-1.7	-1.9	-1.2	-1.5	-1.2	-1.0	-0.8	-0.6	-1.5	-1.7	-1.6	-1.5
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	0.8	0.5	0.9	0.8	0.8	0.8	0.8	0.8	0.6	1.4	0.7	0.6	0.7	0.7	0.8	0.1
Had menopause	0.5	0.6	2.7	1.2	0.6	1.6	0.4	0.6	1.1	0.1	0.4	0.7	0.9	0.2	0.5	0.5	0.5	0.5	0.9
Time employed in main current job	0.5	0.6	1.6	-0.8	-0.7	-0.4	-0.6	-0.6	-0.6	-0.9	-0.7	-1.3	-0.9	-1.0	-0.9	-0.8	-0.5	-0.6	-0.4
Prospective memory result	0.5	0.6	2.1	0.7	0.6	-0.4	-1.1	-1.0	-0.2	-0.2	-1.0	0.4	-0.2	-0.1	0.7	-0.5	-1.2	-0.6	-1.4
Medication: Amlodipine	0.5	0.7	1.4	-1.0	-1.1	-0.1	-0.8	-0.7	-0.7	-0.8	-0.8	-1.2	-0.7	-1.0	-0.7	-0.8	-0.7	-1.0	0.0
Suffer from ‘nerves’	0.5	0.8	2.3	-0.5	-0.5	-0.6	-0.9	-0.9	-0.7	-1.2	-0.9	-0.8	-0.5	-1.0	-1.0	-1.1	-1.0	-0.6	-1.5
Mineral and other dietary supplements	0.5	0.7	1.2	0.3	0.5	0.9	1.1	1.1	0.9	0.8	1.1	0.3	0.6	0.7	0.3	1.0	1.1	0.9	0.6
Arm fat mass (left)	0.5	1.9	3.9	0.5	0.7	1.5	1.9	2.0	1.6	0.9	1.9	1.4	-0.6	0.8	0.4	1.5	1.9	1.5	1.5
Guilty feelings	0.5	0.7	2.5	1.6	1.2	0.5	0.4	0.4	0.9	0.9	0.4	0.7	1.1	0.7	1.2	0.5	0.4	0.7	0.7
Alcohol drinker status: Never	0.5	0.7	2.1	-0.0	-0.1	-0.2	-1.0	-1.1	-0.4	-1.4	-1.1	0.3	-0.5	-1.0	-0.6	-1.2	-0.8	-0.5	-0.9
Pack years of smoking	0.5	0.7	3.8	-0.3	-0.3	-1.9	-0.8	-0.9	-1.1	-0.9	-0.7	-0.1	-1.1	-0.2	-0.1	-0.6	-0.8	-0.9	-0.6
Impedance of whole body	0.5	2.7	8.6	-1.2	-1.4	-2.9	-1.7	-1.8	-2.0	-1.1	-1.6	-1.6	-1.0	-1.0	-0.7	-1.6	-1.9	-1.8	-1.6
Verbal and Numeric Reasoning (VNR)	0.4	1.0	4.0	0.2	0.2	0.9	1.2	1.0	0.8	1.4	1.1	0.7	0.8	0.8	0.3	0.9	1.2	1.1	2.0
Crohns Disease (2012)	0.4	0.6	2.2	1.1	0.0	1.0	0.2	0.3	0.7	0.0	0.3	0.6	1.1	0.8	1.2	0.6	0.3	0.5	1.5
Neuroticism (2016)	0.4	0.6	2.3	0.9	1.1	-0.9	0.5	0.5	0.3	0.5	0.6	1.0	0.1	1.2	1.5	0.7	0.4	0.5	0.1
Number of treatments/medications taken	0.4	0.8	1.3	-1.0	-0.8	-0.6	-0.8	-0.9	-1.0	-1.1	-0.9	-1.0	-0.1	-1.0	-1.0	-1.0	-0.6	-0.8	-1.0
Hearing difficulty/problems: Yes	0.4	0.6	1.2	-1.1	-0.9	-1.0	-0.4	-0.6	-0.8	-0.8	-0.5	-0.8	-0.9	-0.5	-0.8	-0.5	-0.1	-0.5	-0.9
Severe depression (siblings)	0.4	0.4	1.6	-0.8	-1.0	-1.1	-0.4	-0.4	-0.8	-0.3	-0.4	-1.3	-0.4	-0.3	-0.3	-0.4	-0.4	-0.9	0.0
Average weekly fortified wine intake	0.4	0.5	1.7	-0.2	-0.2	0.4	1.3	1.3	0.7	-0.5	1.1	0.3	-0.6	0.1	-0.4	0.8	1.1	0.5	-0.2
Supplements: Glucosamine	0.4	0.5	0.9	-0.6	-0.6	0.4	-0.9	-0.8	-0.5	-0.5	-0.9	-0.5	-0.6	-0.9	-0.6	-0.9	-1.0	-0.7	-0.4
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	2.3	0.1	0.1	1.3	0.6	0.5	0.6	0.6	0.5	0.8	0.8	0.2	-0.0	0.3	0.7	0.8	1.5
Impedance of arm (left)	0.4	1.7	5.9	-1.0	-1.1	-2.4	-1.2	-1.2	-1.5	-0.7	-1.2	-1.6	-0.6	-0.8	-0.5	-1.2	-1.5	-1.4	-1.4
Pulse wave reflection index	0.4	0.4	2.0	0.9	0.7	1.4	-0.0	0.2	0.8	0.6	0.1	1.0	0.4	0.2	0.9	0.4	-0.3	0.2	-0.5
Glaucoma (self-reported)	0.4	0.4	1.9	0.3	0.0	1.1	0.7	0.6	0.6	0.1	0.6	0.1	0.3	0.1	-0.3	0.5	1.1	0.6	1.4
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.1	-0.9	-0.9	-0.8	-0.3	-0.5	-0.9	-0.6	-0.4	-1.1	-1.0	-0.6	-1.0	-0.7	-0.1	-0.6	0.3
High blood pressure (siblings)	0.4	0.6	4.2	-0.3	-0.5	0.9	0.6	0.3	0.2	-0.5	0.4	0.5	-0.0	-0.2	-1.1	-0.1	1.2	0.8	2.0
Age at first live birth	0.4	0.7	1.4	-0.2	-0.5	0.4	-1.1	-1.1	-0.5	-1.0	-1.1	-0.9	0.1	-1.2	-0.9	-1.1	-1.0	-0.7	-0.6
Eye problems/disorders: None of the above	0.4	0.4	2.4	-0.7	-0.9	-0.6	-0.1	0.0	-0.4	0.2	-0.1	-1.6	-0.1	-0.4	-0.4	-0.1	-0.6	-0.6	-1.3
Neck or shoulder pain in last month	0.4	0.5	1.9	-0.6	-0.8	-0.8	-0.4	-0.3	-0.6	-0.3	-0.4	-1.4	-0.9	-0.5	-0.3	-0.3	-0.7	-0.8	-1.3
Medication: Allopurinol	0.4	0.5	1.1	0.3	0.6	-0.0	1.0	1.1	0.6	0.8	1.0	-0.4	0.2	0.7	0.7	1.0	0.9	0.5	0.3
Age at last live birth	0.4	0.6	1.6	0.0	-0.4	0.1	-1.0	-0.9	-0.4	-0.9	-1.0	-0.9	-0.0	-1.0	-0.6	-0.9	-1.2	-0.7	-1.3
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.4	0.8	0.6	-0.1	0.6	0.8	0.7	0.8	0.7	-0.1	0.9	0.8	1.2	0.9	0.2	0.2	-0.7
Knee pain experienced in last month	0.4	0.7	2.2	-0.6	-0.7	-0.1	-0.7	-0.6	-0.5	-1.1	-0.7	-0.6	-1.5	-1.1	-0.9	-0.8	-0.6	-0.8	-0.8
Mood swings	0.4	0.8	2.6	1.5	1.6	-0.3	-0.0	0.1	0.6	0.7	0.1	0.9	0.9	0.8	1.6	0.4	-0.3	0.3	-1.0
Osteoporosis (self-reported)	0.4	0.5	1.1	-1.0	-1.0	-1.1	-0.5	-0.5	-0.8	-0.7	-0.5	-0.7	-1.0	-0.7	-0.9	-0.7	-0.4	-0.6	0.0
Mother’s age at death	0.4	0.5	3.1	0.3	0.1	1.8	0.3	0.3	0.7	-0.4	0.2	1.2	-0.6	-0.3	-0.4	0.1	0.5	0.6	1.2
Depressed Affect (Nagel 2018)	0.3	0.7	2.7	1.4	1.4	0.1	0.2	0.4	0.8	1.1	0.3	0.8	0.8	0.9	1.6	0.6	-0.0	0.3	-0.1
Major Depression (MDD)	0.3	0.4	3.5	-0.2	0.0	-1.9	-0.4	-0.5	-0.8	0.0	-0.4	0.0	0.0	0.3	0.2	-0.1	-0.4	-0.6	-0.6
Lupus	0.3	0.4	0.8	-0.6	-0.5	-0.6	-0.9	-0.9	-0.9	-0.3	-0.8	-0.4	-0.6	-0.5	-0.4	-0.8	-0.8	-0.8	0.0
Blood Red Count	0.3	3.0	5.9	1.2	1.1	0.1	2.3	2.2	1.4	1.4	2.3	1.6	-0.3	2.0	1.3	2.1	2.4	1.8	2.2
Heel T-Score	0.3	2.3	5.0	-2.2	-2.1	-1.8	-0.8	-0.7	-1.5	-1.1	-0.8	-2.2	-1.9	-1.3	-1.6	-1.0	-0.9	-1.5	-1.7
BMI	0.3	1.6	3.2	0.5	0.7	1.6	1.6	1.6	1.3	0.1	1.5	1.6	-1.1	0.4	-0.1	1.0	1.8	1.4	1.8
Lung FVC	0.3	1.5	4.2	1.9	2.1	-0.3	0.5	0.7	1.0	0.7	0.7	1.2	1.4	1.6	2.1	1.2	0.4	0.7	-0.9
Average weekly spirits intake	0.3	0.4	0.9	0.4	0.4	0.6	0.8	0.9	0.7	0.3	0.8	-0.1	-0.1	0.4	0.3	0.8	0.9	0.4	0.7
Diabetes (mother)	0.3	0.4	2.7	-0.9	-0.5	-1.0	0.1	0.0	-0.6	-0.4	0.1	0.1	-1.7	-0.1	-0.5	-0.2	0.2	-0.2	1.2
Fed-up feelings	0.3	0.5	1.2	0.1	0.3	-0.9	-1.1	-1.0	-0.5	-0.1	-0.9	-0.1	-0.5	-0.2	0.4	-0.6	-1.1	-0.7	-0.9
Taking other prescription medications	0.3	0.5	1.3	-0.9	-0.7	-0.5	-0.4	-0.4	-0.7	-1.1	-0.4	-1.0	-1.1	-0.8	-1.0	-0.6	-0.0	-0.7	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	0.6	1.0	-0.1	-0.0	-0.0	0.2	0.7	0.1	0.9	0.2	0.7	1.1	0.3	-0.2	0.2	-0.1
Impedance of leg (left)	0.3	1.4	6.0	-0.6	-0.7	-2.4	-1.3	-1.4	-1.5	-0.9	-1.2	-0.6	-0.6	-0.4	-0.2	-1.2	-1.4	-1.2	-1.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.1	0.4	0.4	-0.2	1.0	1.1	0.6	0.7	1.0	-0.8	0.3	0.5	0.5	0.9	0.7	0.3	-0.2
Alcohol intake versus 10 years previously	0.3	0.4	1.8	0.7	0.5	-0.5	-0.5	-0.2	0.0	0.8	-0.3	0.4	0.7	0.6	1.4	0.3	-0.6	-0.4	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.4	-0.1	-0.2	-1.2	-0.7	-0.6	-0.7	-0.2	-0.6	-0.5	-1.2	-0.1	0.4	-0.2	-0.9	-1.0	-0.6
Hair/balding pattern: Pattern 3	0.3	0.4	0.9	-0.4	-0.4	-0.7	-0.9	-0.9	-0.7	-0.6	-0.9	0.1	-0.7	-0.5	-0.4	-0.8	-0.8	-0.5	-0.0
Happiness	0.3	0.4	2.1	0.1	0.1	-1.5	-0.1	-0.1	-0.3	-0.1	-0.0	-0.5	-0.8	0.3	0.5	0.2	-0.3	-0.4	-1.4
Breastfed as a baby	0.3	0.4	1.0	1.0	1.0	-0.2	0.4	0.4	0.6	0.3	0.5	0.6	0.7	0.6	0.8	0.5	0.4	0.5	-0.4
Peak expiratory flow (PEF)	0.3	0.8	2.6	0.9	1.3	0.7	0.7	0.7	0.9	0.4	0.7	1.6	0.6	0.9	0.9	0.9	0.6	0.9	-0.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.3	-1.1	-1.0	1.5	-0.3	-0.2	-0.0	-0.5	-0.4	-0.4	-0.2	-1.0	-1.0	-0.5	-0.3	-0.2	-0.1
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	3.4	-0.1	-0.1	-1.3	0.5	0.4	-0.3	0.2	0.5	0.4	-1.8	0.4	-0.1	0.2	0.6	0.1	1.5
Worry too long after embarrassment	0.3	0.5	1.5	1.1	1.2	0.9	0.3	0.4	0.8	0.4	0.4	1.2	0.3	0.5	0.8	0.4	0.2	0.5	0.6
Wheeze or whistling in the chest in last year	0.3	0.5	2.6	-0.0	-0.0	0.7	0.8	0.7	0.4	0.1	0.7	0.3	-0.4	0.2	-0.2	0.4	1.2	0.6	1.6
Emphysema/chronic bronchitis	0.3	0.3	1.7	-0.8	-0.8	-1.1	0.1	-0.1	-0.6	-0.3	-0.0	-0.2	-1.3	-0.2	-0.6	-0.2	0.1	-0.4	0.4
Alcohol intake frequency.	0.3	0.6	2.2	1.1	1.0	-1.3	-0.2	-0.1	0.1	-0.1	-0.0	0.9	-0.4	0.8	1.5	0.4	-0.3	-0.1	-1.3
Hypertension (Self-reported)	0.3	0.9	1.7	-1.1	-1.0	-0.4	-1.2	-1.3	-1.2	-1.0	-1.2	-0.6	-0.4	-1.0	-1.0	-1.2	-0.9	-0.9	0.1
Illnesses of siblings: Diabetes	0.3	0.4	2.8	0.8	0.8	0.4	-0.2	-0.2	0.3	-0.0	-0.2	1.7	0.2	0.2	0.3	-0.1	0.0	0.5	1.0
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.1	0.5	0.9	0.7	-0.2	-0.0	0.4	1.0	-0.0	0.6	0.6	0.5	1.1	0.3	-0.3	0.0	-0.1
Diabetes diagnosed by doctor	0.3	0.5	4.1	0.1	0.3	0.1	0.6	0.5	0.2	0.8	0.6	0.9	-0.3	0.7	0.4	0.6	0.7	0.5	2.0
Medication for cholesterol	0.3	0.4	2.8	0.3	0.2	-0.6	0.6	0.7	0.4	0.4	0.6	0.3	-1.7	0.4	0.4	0.6	0.7	0.3	1.0
Osteoarthritis (self-reported)	0.3	0.4	1.2	-0.6	-0.6	-0.5	-0.5	-0.4	-0.5	-0.6	-0.5	-1.0	-1.1	-0.7	-0.4	-0.5	-0.6	-0.8	-0.7
Miserableness	0.3	0.5	1.2	0.9	0.9	-0.4	-0.9	-0.7	-0.1	0.2	-0.7	0.7	0.2	0.2	1.1	-0.3	-1.1	-0.5	-0.7
Hearing aid user	0.3	0.3	1.8	-0.1	-0.7	-0.9	-0.3	-0.3	-0.3	-0.8	-0.3	-0.7	-0.3	-0.4	-0.2	-0.2	-0.4	-0.6	-1.4
Medication: Paracetamol	0.3	0.5	1.2	-0.4	-0.8	-0.3	-0.7	-0.7	-0.5	-1.1	-0.7	-0.3	-1.0	-1.0	-0.7	-0.9	-0.8	-0.7	-0.7
Ever smoked	0.3	0.5	0.9	0.3	0.4	0.7	0.8	0.9	0.8	0.8	0.8	0.4	0.5	0.6	0.7	0.9	0.8	0.5	0.8
Average weekly beer plus cider intake	0.3	0.4	1.0	0.9	0.9	0.0	0.1	0.1	0.2	0.7	0.2	1.0	0.8	0.8	1.0	0.4	0.1	0.3	0.4
Risk taking	0.3	0.4	1.7	0.3	0.1	1.3	0.6	0.7	0.7	0.4	0.6	-0.0	0.4	-0.1	-0.1	0.2	0.8	0.6	1.1
Age started oral contraceptive pill	0.3	0.4	1.3	-0.1	-0.2	0.3	-0.8	-0.8	-0.3	-1.2	-0.8	0.4	-0.6	-0.7	-0.5	-0.7	-0.9	-0.5	-0.6
Unable to work because of sickness or disability	0.3	0.4	0.9	0.6	0.8	-0.9	0.5	0.4	0.2	0.7	0.5	0.3	0.5	0.9	0.9	0.6	0.4	0.3	0.3
Basal cell carcinoma (self-reported)	0.3	0.4	2.7	0.4	0.3	-1.6	-0.6	-0.7	-0.6	-0.3	-0.5	0.7	-0.5	0.5	0.6	-0.3	-0.4	-0.3	0.3
Depression (Nagel 2018)	0.2	0.3	1.0	0.8	0.7	0.2	0.1	0.3	0.6	0.7	0.2	-0.0	0.7	0.3	1.0	0.4	-0.2	0.0	-0.9
Crohns Disease (2017)	0.2	0.4	2.4	0.6	0.5	0.3	0.3	0.4	0.4	0.8	0.4	0.3	0.9	0.5	0.8	0.5	0.4	0.3	1.6
Irritable Bowel Disease (IBD)	0.2	0.4	3.1	-0.1	-0.2	0.8	0.6	0.6	0.4	0.6	0.5	-0.3	0.8	0.0	-0.1	0.4	0.7	0.3	1.8
Ulcerative Colitis (UC)	0.2	0.3	1.4	-0.4	-0.5	0.9	0.6	0.6	0.3	0.1	0.5	-0.4	0.5	-0.3	-0.7	0.2	0.7	0.3	1.2
Primary Biliary Cirrhosis	0.2	0.3	1.4	0.2	0.0	0.1	-0.9	-0.9	-0.4	0.1	-0.8	0.6	0.1	-0.1	0.3	-0.5	-1.2	-0.5	-0.2
Respiratory disease	0.2	0.4	2.3	-0.1	-0.3	0.2	0.9	0.8	0.2	-0.0	0.8	-0.3	-0.2	0.2	-0.4	0.4	1.1	0.5	1.5
Neuroticism	0.2	0.4	1.0	0.4	0.4	-0.9	-0.9	-0.7	-0.4	0.0	-0.7	-0.2	-0.5	-0.2	0.5	-0.5	-1.0	-0.8	-0.7
Tanning	0.2	2.5	6.5	2.1	1.7	2.5	1.2	1.4	2.0	1.0	1.3	1.2	2.4	1.0	1.2	1.4	1.1	1.5	0.5
Systolic blood pressure, automated reading	0.2	0.7	1.3	-0.5	-0.6	-0.5	-1.0	-1.1	-0.9	-1.2	-1.0	-0.4	-0.2	-0.8	-0.7	-1.0	-1.1	-0.7	-1.0
Medication: Metformin	0.2	0.3	2.1	0.1	0.2	0.5	0.3	0.2	0.1	0.3	0.2	1.0	-0.1	0.3	-0.1	0.2	0.4	0.4	1.5
Trunk fat percentage	0.2	0.8	1.8	-0.0	0.1	0.2	1.4	1.3	0.7	0.6	1.3	0.6	-1.2	0.5	0.1	0.8	1.3	0.8	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.7	0.6	0.7	0.4	0.1	0.2	0.5	0.9	0.2	0.4	0.4	0.5	0.8	0.4	-0.0	0.3	-0.6
High blood pressure	0.2	0.6	1.1	-0.9	-0.8	-0.4	-0.9	-1.1	-1.0	-0.8	-1.0	-0.3	-0.3	-0.7	-0.7	-0.9	-0.6	-0.7	0.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.0	-0.0	-0.4	-0.5	-0.4	-0.3	-0.3	-0.9	-0.4	-0.4	-1.0	-0.5	-0.2	-0.4	-0.4	-0.6	-0.2
High blood pressure (mother)	0.2	0.2	0.6	-0.3	-0.2	-0.1	-0.6	-0.6	-0.6	-0.6	-0.6	0.6	-0.8	-0.3	-0.3	-0.5	-0.6	-0.4	0.4
Body mass index (BMI)	0.2	1.0	1.9	0.1	0.2	1.2	1.4	1.4	1.0	0.4	1.3	0.8	-1.1	0.3	-0.2	0.9	1.4	0.9	1.3
Waist circumference	0.2	0.8	2.5	-0.4	-0.3	0.7	1.2	1.2	0.6	0.2	1.1	0.7	-1.6	0.1	-0.5	0.7	1.3	0.7	1.3
Mouth/teeth dental problems	0.2	0.3	1.8	0.6	0.7	1.3	-0.5	-0.3	0.4	-0.4	-0.4	0.6	0.4	-0.4	0.0	-0.3	-0.6	0.1	-1.0
Diabetes (self-reported)	0.2	0.3	2.0	-0.5	-0.0	-0.5	0.2	0.0	-0.4	0.6	0.2	0.6	-0.6	0.5	-0.0	0.2	0.3	0.1	1.4
Illnesses of siblings	0.2	0.2	1.2	-0.2	0.1	-0.7	0.0	0.2	-0.0	0.7	0.2	-0.6	0.2	0.3	0.7	0.4	-0.3	-0.4	-1.1
Neuroticism score	0.2	0.5	1.8	0.4	0.6	-0.6	-1.0	-0.9	-0.3	-0.2	-0.9	0.1	-0.4	-0.4	0.3	-0.7	-1.2	-0.5	-1.4
Arm fat percentage (right)	0.2	0.6	1.6	-0.2	-0.2	0.5	1.2	1.2	0.7	0.3	1.1	0.4	-1.2	0.2	-0.2	0.7	1.1	0.6	1.1
Father’s age at death	0.2	0.3	1.9	-0.1	-0.1	0.2	0.2	0.1	0.1	-0.3	0.1	0.4	-1.4	-0.3	-0.5	0.0	0.3	0.0	1.2
Pulse wave Arterial Stiffness index	0.2	0.3	1.5	-0.0	-0.1	0.1	-0.4	-0.1	0.0	-0.2	-0.2	0.1	-1.2	-0.3	0.3	-0.0	-0.7	-0.6	-1.2
Length of working week for main job	0.2	0.2	0.5	0.3	0.4	-0.7	0.6	0.7	0.3	0.1	0.6	-0.1	-0.0	0.5	0.7	0.5	0.3	0.2	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.8	0.8	0.5	0.5	-0.7	-0.5	0.1	-0.0	-0.6	-0.0	-0.0	-0.1	0.5	-0.1	-0.8	-0.5	-0.9
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.2	-0.1	-0.1	-1.1	0.3	0.2	-0.3	0.0	0.3	0.3	-0.7	0.4	0.1	0.1	0.5	0.1	0.9
Body fat percentage	0.2	0.6	1.8	-0.1	-0.0	0.1	1.2	1.2	0.5	0.4	1.1	0.7	-1.3	0.3	-0.0	0.7	1.1	0.6	1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.4	0.6	0.4	0.4	-0.2	-0.1	0.3	0.2	-0.1	0.2	1.2	0.1	0.6	0.0	-0.3	-0.0	-0.5
Migraine (self-reported)	0.2	0.2	1.5	0.8	0.7	-0.1	-0.1	-0.1	0.3	-0.0	-0.1	1.2	0.3	0.4	0.6	0.1	-0.1	0.3	-0.4
Medication: Seretide 50 evohaler	0.2	0.3	0.7	0.2	0.4	0.2	0.7	0.7	0.4	0.3	0.7	0.2	-0.0	0.5	0.3	0.6	0.8	0.6	0.7
Number of full sisters	0.2	0.3	1.1	-1.1	-0.6	-1.0	0.0	-0.1	-0.7	0.0	-0.0	-0.7	-0.7	-0.1	-0.6	-0.2	0.2	-0.2	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.7	0.1	0.5	-1.3	0.0	-0.0	-0.3	-0.1	0.1	0.8	-0.6	0.5	0.5	0.0	0.1	0.1	-0.2
Average weekly red wine intake	0.2	0.3	1.2	-0.7	-0.4	0.9	0.6	0.5	0.2	0.5	0.5	-0.1	0.2	0.0	-0.4	0.3	0.6	0.4	1.1
Qualifications: nursing, teaching	0.2	0.3	0.5	-0.5	-0.7	0.5	-0.6	-0.6	-0.3	-0.3	-0.6	-0.4	-0.3	-0.7	-0.6	-0.6	-0.7	-0.5	-0.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.9	-0.1	-0.3	0.2	-0.5	-0.7	-0.4	-0.4	-0.6	0.1	0.3	-0.6	-0.7	-0.8	-0.3	-0.0	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.2	0.4	0.4	-0.6	0.3	0.4	0.2	1.1	0.4	-0.7	0.6	0.6	0.7	0.6	0.3	0.1	-0.1
Medication: Gliclazide	0.2	0.2	0.8	-0.2	-0.2	0.1	0.7	0.6	0.1	0.0	0.6	0.1	-0.1	0.1	-0.4	0.3	0.6	0.4	0.9
Financial situation satisfaction	0.2	0.3	0.6	-0.3	-0.3	-0.7	-0.7	-0.6	-0.6	-0.5	-0.6	-0.2	-0.7	-0.3	0.1	-0.5	-0.6	-0.7	-0.7
Medication: Bendroflumethiazide	0.2	0.4	1.1	-0.5	-0.6	0.8	-0.7	-0.7	-0.4	-0.2	-0.7	-0.1	0.1	-0.7	-0.7	-0.6	-0.4	-0.4	1.1
Leg fat percentage (left)	0.2	0.7	1.9	-0.0	0.0	0.4	1.2	1.2	0.6	0.3	1.1	0.9	-1.3	0.4	-0.0	0.7	1.2	0.6	1.4
Ever depressed for a whole week	0.2	0.2	0.7	-0.3	-0.1	0.1	-0.8	-0.7	-0.4	-0.4	-0.7	-0.1	-0.8	-0.4	-0.2	-0.4	-0.5	-0.7	-0.3
Commuting to job workplace: Cycle	0.2	0.2	0.5	0.6	0.7	0.3	0.0	0.0	0.3	0.6	0.1	0.7	0.6	0.5	0.5	0.3	-0.0	0.2	-0.1
Supplements: Calcium	0.2	0.2	0.9	-0.3	-0.3	-0.4	-0.4	-0.4	-0.3	-0.9	-0.4	-0.1	-0.5	-0.5	-0.3	-0.5	-0.4	-0.3	-0.6
Neuroticism (Nagel 2018)	0.1	0.3	1.5	0.3	0.2	-1.2	-0.7	-0.6	-0.4	0.1	-0.5	-0.5	-0.3	0.0	0.5	-0.3	-0.7	-0.5	-0.6
Reaction Time	0.1	0.2	1.1	0.5	0.3	0.4	-0.4	-0.3	0.2	-0.7	-0.4	0.5	0.3	-0.3	-0.1	-0.3	-0.5	-0.0	-1.1
Fasting Glucose	0.1	0.2	0.5	0.3	-0.4	0.1	0.7	0.7	0.4	0.2	0.7	0.1	0.3	0.2	0.4	0.3	0.4	0.2	0.4
Medication for hormone replacement therapy	0.1	0.1	1.2	-0.3	0.1	-1.1	0.1	0.1	-0.4	-0.2	0.1	0.1	-0.2	0.4	0.2	0.1	0.2	-0.0	-0.5
Vitamin and mineral supplements	0.1	0.1	0.3	-0.6	-0.5	-0.6	0.0	-0.2	-0.4	-0.1	-0.0	-0.4	-0.1	-0.0	-0.5	-0.2	0.2	0.1	0.5
Medication: Co-codamol	0.1	0.1	0.7	-0.5	-0.5	-0.3	0.0	0.0	-0.1	-0.2	-0.0	-0.4	-0.8	-0.4	-0.5	-0.2	0.1	-0.0	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.5	0.0	0.1	0.7	0.5	0.4	0.4	0.3	0.4	0.4	0.6	0.1	-0.3	0.2	0.6	0.6	0.4
Qualifications: CSEs or equivalent	0.1	0.2	1.3	-0.2	0.0	-0.4	-0.4	-0.4	-0.3	0.1	-0.4	0.2	0.0	-0.0	0.1	-0.2	-0.6	-0.3	-1.1
Medication: Atenolol	0.1	0.1	0.8	0.0	-0.1	0.3	0.1	0.1	0.1	-0.1	0.1	-0.2	0.9	-0.0	-0.1	0.0	0.0	0.2	-0.4
Medication: Levothyroxine sodium	0.1	0.2	1.0	0.5	0.3	1.0	0.5	0.6	0.7	0.1	0.4	0.2	0.6	-0.1	-0.0	0.2	0.6	0.5	0.2
Number of incorrect matches in round	0.1	0.1	0.8	0.2	0.2	-0.0	-0.2	-0.1	0.1	-0.4	-0.2	-0.2	0.3	-0.3	0.0	-0.2	-0.1	-0.2	-0.9
Hearing difficulty/problems with background noise	0.1	0.2	0.5	-0.4	-0.0	-0.0	-0.5	-0.7	-0.5	-0.6	-0.6	0.1	-0.2	-0.3	-0.6	-0.6	-0.1	-0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.0	-0.9	-0.8	0.0	-0.5	-0.6	-0.6	-0.3	-0.6	-0.4	-0.3	-0.6	-1.0	-0.7	-0.3	-0.3	-0.3
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.8	0.7	0.7	-0.0	-0.2	-0.1	0.1	0.4	-0.0	0.4	0.1	0.6	0.9	0.3	0.0	-0.2	0.4
Financial difficulties in last 2 years	0.1	0.1	0.5	0.2	0.3	0.4	0.3	0.3	0.3	-0.2	0.3	0.7	-0.4	0.0	-0.1	0.1	0.6	0.5	0.4
Pain all over the body in last month	0.1	0.1	0.3	0.0	0.3	0.0	-0.3	-0.5	-0.2	-0.0	-0.4	0.1	0.4	-0.1	-0.3	-0.3	-0.0	0.0	0.3
Medication: Ramipril	0.1	0.2	0.6	-0.1	-0.1	0.1	-0.5	-0.4	-0.2	-0.4	-0.5	0.4	-0.1	-0.3	0.1	-0.3	-0.8	-0.4	-0.8
Impedance of arm (right)	0.1	0.6	3.1	-0.2	-0.4	-1.8	-0.6	-0.5	-0.7	-0.1	-0.5	-1.2	0.0	-0.2	0.2	-0.5	-0.9	-0.9	-1.0
Qualifications: A levels/AS levels or equivalent	0.1	0.2	2.2	-0.4	-0.4	1.5	-0.1	-0.2	0.2	0.2	-0.2	0.0	0.6	-0.5	-0.5	-0.2	-0.2	0.1	0.6
Asthma	0.1	0.2	0.6	-0.5	-0.5	-0.7	0.3	0.1	-0.4	-0.8	0.2	-0.7	-0.6	-0.3	-0.6	-0.2	0.4	-0.0	0.2
Depression (self-reported)	0.1	0.1	0.4	-0.3	-0.2	-0.6	0.2	0.0	-0.2	0.0	0.1	-0.6	-0.2	-0.0	-0.4	-0.0	0.2	0.0	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.7	0.4	0.4	0.0	-0.0	0.2	0.3	0.7	0.1	-0.0	0.2	0.4	0.8	0.4	-0.2	-0.1	-0.5
Blood clot in the leg (DVT)	0.1	0.1	0.7	0.2	-0.1	-0.2	-0.1	0.0	0.1	-0.4	-0.0	-0.1	-0.9	-0.1	0.1	0.2	-0.1	-0.3	-0.4
Leg fat percentage (right)	0.1	0.5	2.7	-0.4	-0.3	-0.0	0.9	0.9	0.2	0.0	0.8	0.4	-1.6	0.1	-0.3	0.4	0.9	0.3	0.9
Number of full brothers	0.1	0.2	0.4	0.1	0.0	-0.3	-0.4	-0.6	-0.4	-0.5	-0.5	0.2	0.0	-0.2	-0.5	-0.6	-0.0	0.2	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.3	0.3	0.5	0.5	-0.4	-0.3	0.1	0.3	-0.3	0.3	0.3	0.0	0.3	-0.1	-0.4	0.0	-0.3
Qualifications: College or University degree	0.1	0.2	1.4	-0.1	0.0	0.5	0.4	0.4	0.3	0.6	0.3	-0.6	0.8	0.1	0.1	0.2	0.3	0.3	1.2
Medication for pain relief, constipation, heartburn	0.1	0.1	0.5	0.1	0.1	0.7	0.2	0.3	0.3	0.4	0.2	0.0	0.2	0.2	0.1	0.3	0.2	0.2	0.6
Medication: Ibuprofen	0.1	0.1	0.5	0.3	0.4	-0.0	0.2	0.1	0.1	0.2	0.2	0.4	-0.4	0.2	0.1	0.1	0.5	0.4	0.7
Heart disease (mother)	0.1	0.1	0.5	-0.7	-0.6	0.0	0.3	0.2	-0.3	0.0	0.2	-0.2	-0.3	-0.1	-0.6	0.1	0.2	0.1	0.3
Overall health rating	0.1	0.2	1.1	-0.4	-0.3	-0.8	-0.4	-0.3	-0.5	-0.1	-0.3	-0.3	-1.1	-0.1	0.1	-0.1	-0.3	-0.6	-0.7
Leg pain on walking	0.1	0.2	1.4	0.6	0.2	1.2	0.1	0.3	0.7	-0.0	0.2	0.3	-0.1	-0.1	0.2	0.3	-0.0	0.2	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.3	0.4	0.5	0.3	0.3	0.4	0.4	0.2	0.3	0.5	0.0	0.4	0.6	0.4	0.3	0.4	-0.1
Supplements: Vitamin C	0.1	0.2	0.4	0.4	0.1	0.4	0.5	0.6	0.5	0.1	0.5	0.3	0.1	0.3	0.4	0.6	0.3	0.2	-0.5
Arm fat percentage (left)	0.1	0.4	1.9	-0.4	-0.3	0.4	0.9	0.9	0.4	0.1	0.8	0.3	-1.4	-0.1	-0.4	0.4	0.8	0.4	0.9
Commuting to job workplace: Walk	0.1	0.1	0.3	-0.3	-0.3	-0.6	0.5	0.5	-0.0	-0.2	0.5	-0.2	-0.5	0.0	-0.2	0.1	0.5	0.2	-0.1
Asthma (self-reported)	0.1	0.2	0.4	-0.5	-0.5	-0.6	0.4	0.3	-0.3	-0.6	0.3	-0.7	-0.6	-0.2	-0.6	-0.1	0.5	0.1	0.3
Number of self-reported non-cancer illnesses	0.1	0.2	0.6	-0.3	-0.4	-0.3	-0.2	-0.3	-0.3	-0.4	-0.3	-0.8	0.4	-0.5	-0.4	-0.5	-0.2	-0.3	-0.7
Commuting to job workplace: Public transport	0.1	0.1	0.3	-0.2	-0.2	-0.0	-0.4	-0.5	-0.4	-0.4	-0.4	0.5	-0.2	-0.2	-0.4	-0.4	-0.4	-0.1	-0.5
Eye problems/disorders: Glaucoma	0.1	0.1	1.4	0.0	-0.1	0.2	0.2	0.0	0.0	-0.2	0.1	-0.0	-0.1	-0.0	-0.3	0.0	0.6	0.2	1.2
Medication: Blood pressure	0.1	0.2	1.0	-0.1	-0.0	0.7	-0.3	-0.4	-0.2	-0.4	-0.3	0.8	0.6	-0.2	-0.4	-0.4	-0.1	0.1	1.0
Medication: Lisinopril	0.1	0.1	0.4	-0.1	0.1	0.5	-0.0	-0.2	0.0	-0.1	-0.1	0.5	0.6	-0.0	-0.2	-0.2	0.0	0.3	0.4
Number of operations (self-reported)	0.1	0.2	0.6	0.4	0.1	0.7	0.4	0.5	0.6	-0.0	0.4	-0.0	-0.1	-0.2	-0.0	0.3	0.6	0.2	0.8
Fractured/broken bones in last 5 years	0.1	0.1	0.3	0.2	-0.2	0.2	-0.6	-0.5	-0.2	-0.2	-0.5	0.4	-0.1	-0.3	0.1	-0.5	-0.5	-0.3	0.4
Diastolic blood pressure, automated reading	0.1	0.2	0.8	0.0	0.2	-0.3	-0.2	-0.2	-0.1	-0.6	-0.2	0.9	-0.9	0.0	0.1	-0.2	-0.3	0.0	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.6	0.3	-0.0	0.1	-0.1	0.1	0.3	-0.5	-0.0	-0.1	-0.8	-0.2	0.1	0.1	-0.1	-0.3	-0.5
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.0	0.1	0.4	-0.4	0.0	0.6	0.2	0.2	0.1	0.0	0.1	-0.1	0.1	-0.3	-0.6	-0.1	0.1	0.0	0.1
Smoking Status	0.0	0.1	0.3	-0.2	-0.5	0.0	-0.0	0.2	-0.0	0.4	0.0	-0.6	-0.2	-0.2	0.1	0.1	0.0	-0.4	0.5
Hair Pigment	0.0	0.4	4.9	0.2	0.4	-0.2	0.1	0.3	0.2	-0.1	0.2	0.8	0.2	0.3	0.6	0.3	-0.4	-0.2	-2.2
Alcohol usually taken with meals	0.0	0.1	0.3	-0.3	-0.2	0.6	-0.1	-0.2	0.0	0.0	-0.1	0.1	0.0	-0.2	-0.4	-0.2	-0.2	0.2	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.1	0.2	0.2	0.2	-0.3	-0.2	-0.1	-0.1	0.4	-0.1	-0.3	0.1	0.1	0.3	0.0	-0.4	-0.2	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.1	0.4	0.2	0.1	-0.1	-0.2	-0.3	-0.1	-0.1	-0.2	0.5	-0.6	-0.1	-0.2	-0.3	-0.0	0.2	0.2
Headache pain in last month	0.0	0.0	0.2	0.1	0.1	-0.5	0.1	0.1	-0.1	0.1	0.1	0.2	-0.4	0.2	0.2	0.2	-0.1	-0.1	-0.4
Mean time to correctly identify matches	0.0	0.0	0.3	0.4	0.3	0.0	-0.1	-0.1	0.1	-0.4	-0.1	0.3	0.1	-0.1	0.0	-0.1	-0.1	0.0	-0.5
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.4	0.4	0.3	0.0	0.1	0.1	0.3	-0.0	0.1	0.1	-0.6	-0.1	0.1	0.1	-0.1	0.0	-0.4
Pain experienced in last month	0.0	0.1	0.4	0.0	-0.0	-0.5	-0.1	-0.2	-0.2	0.1	-0.1	-0.2	0.6	0.1	0.0	-0.1	-0.0	0.1	0.2

Hub : Genes

APOC2

Models

Trait associations