Best TWAS P=3.56e-08 · Best GWAS P=5.32e-15 conditioned to 2.23e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | FAM124B | 0.08 | 0.00 | lasso | 4 | 0.00 | 4.6e-01 | 6.4 | -5.4 | 6.5e-08 | 0.11 | 0.02 | 0.81 | FALSE |
2 | GTEx | Adrenal Gland | FAM124B | 0.31 | 0.17 | lasso | 4 | 0.17 | 9.2e-07 | 5.5 | -5.5 | 3.7e-08 | 0.09 | 0.02 | 0.95 | TRUE |
3 | GTEx | Muscle Skeletal | KCNE4 | 0.06 | 0.01 | lasso | 2 | 0.00 | 2.4e-01 | -5.5 | -5.5 | 3.6e-08 | 0.41 | 0.19 | 0.06 | TRUE |