Best TWAS P=5.93e-36 · Best GWAS P=1.23e-46 conditioned to 2.44e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | OTUD4 | 0.06 | 0.04 | bslmm | 272 | 0.04 | 2.6e-05 | -11.1 | -8.9 | 4.3e-19 | 0.31 | 0.56 | 0.36 | FALSE |
| 2 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 4.6e-02 | 9.4 | 9.5 | 1.4e-21 | -0.22 | 0.06 | 0.23 | TRUE |
| 3 | GTEx | Pancreas | ANAPC10 | 0.14 | 0.10 | lasso | 3 | 0.10 | 4.3e-05 | -12.7 | 12.5 | 5.9e-36 | -0.38 | 0.32 | 0.11 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | OTUD4 | 0.04 | 0.03 | lasso | 2 | 0.03 | 1.4e-04 | 12.1 | -12.4 | 2.5e-35 | 0.31 | 0.52 | 0.24 | TRUE |