Best TWAS P=2.77e-08 · Best GWAS P=4.3e-07 conditioned to 0.541
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C6orf106 | 0.29 | 0.21 | bslmm | 382 | 0.23 | 6.9e-28 | 4.7 | 5.6 | 2.8e-08 | 0.85 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Nerve Tibial | C6orf106 | 0.11 | 0.07 | enet | 17 | 0.07 | 1.3e-05 | 4.7 | 5.4 | 6.0e-08 | 0.88 | 0.01 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | C6orf106 | 0.30 | 0.26 | bslmm | 372 | 0.33 | 9.3e-44 | 4.9 | 5.2 | 1.8e-07 | 0.84 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | C6orf106 | 0.08 | 0.00 | enet | 15 | 0.05 | 2.5e-05 | -2.0 | 5.2 | 2.7e-07 | 0.36 | 0.02 | 0.25 | FALSE |