TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Relative age of first facial hair
:
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chr6:33,856,903-35,362,848
Best TWAS P=2.77e-08 · Best GWAS P=4.3e-07 conditioned to 0.541
33.8M
34M
34.2M
34.4M
34.6M
34.8M
35M
35.2M
35.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
C6orf106
0.29
0.21
bslmm
382
0.23
6.9e-28
4.7
5.6
2.8e-08
0.85
0.01
0.99
TRUE
2
GTEx
Nerve Tibial
C6orf106
0.11
0.07
enet
17
0.07
1.3e-05
4.7
5.4
6.0e-08
0.88
0.01
0.98
FALSE
3
ROSMAP
Brain Pre-frontal Cortex
C6orf106
0.30
0.26
bslmm
372
0.33
9.3e-44
4.9
5.2
1.8e-07
0.84
0.01
0.99
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
C6orf106
0.08
0.00
enet
15
0.05
2.5e-05
-2.0
5.2
2.7e-07
0.36
0.02
0.25
FALSE