[Hub]/) : Traits : Relative age of first facial hair :

chr6:41,058,968-42,598,371

Best TWAS P=1.25e-12 · Best GWAS P=9.61e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MED20 0.15 0.11 blup 471 0.13 3.1e-15 -5.4 5.5 3.7e-08 0.84 0.02 0.98 FALSE
2 GTEx Adipose Subcutaneous PRICKLE4 0.10 0.09 lasso 8 0.08 9.2e-07 3.8 -6.0 2.6e-09 0.35 0.48 0.51 TRUE
3 GTEx Adipose Subcutaneous MED20 0.08 0.07 enet 9 0.05 4.7e-05 6.2 5.9 3.0e-09 0.97 0.02 0.98 FALSE
4 GTEx Artery Tibial MED20 0.14 0.11 lasso 2 0.09 9.7e-08 6.1 6.1 1.2e-09 0.98 0.01 0.99 FALSE
5 GTEx Esophagus Gastroesophageal Junction MED20 0.19 0.03 enet 11 0.07 2.0e-03 5.7 5.8 8.8e-09 0.76 0.03 0.87 TRUE
6 GTEx Esophagus Mucosa MED20 0.09 0.07 enet 10 0.02 2.7e-02 -5.4 5.5 3.3e-08 0.96 0.03 0.96 TRUE
7 GTEx Heart Atrial Appendage MED20 0.14 0.12 enet 11 0.09 5.9e-05 6.5 6.8 1.3e-11 0.95 0.01 0.99 TRUE
8 GTEx Heart Left Ventricle PRICKLE4 0.11 0.05 lasso 4 0.03 9.8e-03 5.8 -6.2 4.4e-10 -0.96 0.02 0.93 FALSE
9 GTEx Heart Left Ventricle MED20 0.22 0.19 enet 8 0.12 5.8e-07 6.1 6.3 3.6e-10 0.98 0.01 0.99 FALSE
10 GTEx Lung PRICKLE4 0.12 0.05 lasso 3 0.06 2.2e-05 5.8 -5.6 2.0e-08 -0.86 0.04 0.93 TRUE
11 GTEx Muscle Skeletal MED20 0.16 0.15 lasso 4 0.16 6.7e-16 5.8 6.0 2.2e-09 0.92 0.07 0.93 FALSE
12 GTEx Nerve Tibial MED20 0.13 0.11 enet 8 0.10 1.5e-07 6.5 6.2 6.2e-10 0.98 0.01 0.99 FALSE
13 GTEx Thyroid MED20 0.05 0.05 lasso 2 0.02 8.1e-03 6.0 6.2 7.3e-10 0.97 0.02 0.98 FALSE
14 METSIM Adipose MED20 0.13 0.11 enet 27 0.11 2.3e-16 6.3 5.5 3.2e-08 0.90 0.01 0.99 TRUE
15 ROSMAP Brain Pre-frontal Cortex MED20 0.10 0.10 enet 21 0.09 6.0e-12 6.0 5.3 1.4e-07 0.93 0.01 0.99 FALSE
16 YFS Blood BYSL 0.07 0.06 lasso 7 0.09 2.8e-28 6.1 -5.6 2.1e-08 -0.85 0.01 0.99 FALSE
17 YFS Blood MED20 0.04 0.03 lasso 5 0.03 3.6e-11 5.8 5.5 3.7e-08 0.85 0.05 0.95 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PRICKLE4 0.04 0.05 blup 43 0.06 2.2e-07 -3.8 -6.4 1.3e-10 -0.72 0.16 0.84 TRUE
19 The Cancer Genome Atlas Prostate Adenocarcinoma MED20 0.04 0.06 enet 6 0.05 2.6e-06 5.8 5.7 1.5e-08 0.90 0.01 0.99 TRUE
20 The Cancer Genome Atlas Prostate Adenocarcinoma PRICKLE4 0.03 0.00 blup 43 0.01 5.5e-02 6.5 -7.1 1.2e-12 -0.84 0.00 0.77 TRUE
21 The Cancer Genome Atlas Thyroid Carcinoma BYSL 0.05 0.06 enet 7 0.06 4.3e-06 6.0 -6.0 2.1e-09 -0.91 0.00 1.00 FALSE