[Hub]/) : Traits : Relative age of first facial hair : ← →

chr6:41,058,968-42,598,371

Best TWAS P=1.25e-12 · Best GWAS P=9.61e-11 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	PRICKLE4	0.03	0.00	blup	43	0.01	5.5e-02	6.5	-7.1	1.2e-12	-0.84	0.00	0.77	TRUE
7	GTEx	Heart Atrial Appendage	MED20	0.14	0.12	enet	11	0.09	5.9e-05	6.5	6.8	1.3e-11	0.95	0.01	0.99	TRUE
18	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PRICKLE4	0.04	0.05	blup	43	0.06	2.2e-07	-3.8	-6.4	1.3e-10	-0.72	0.16	0.84	TRUE
2	GTEx	Adipose Subcutaneous	PRICKLE4	0.10	0.09	lasso	8	0.08	9.2e-07	3.8	-6.0	2.6e-09	0.35	0.48	0.51	TRUE
5	GTEx	Esophagus Gastroesophageal Junction	MED20	0.19	0.03	enet	11	0.07	2.0e-03	5.7	5.8	8.8e-09	0.76	0.03	0.87	TRUE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	MED20	0.04	0.06	enet	6	0.05	2.6e-06	5.8	5.7	1.5e-08	0.90	0.01	0.99	TRUE
10	GTEx	Lung	PRICKLE4	0.12	0.05	lasso	3	0.06	2.2e-05	5.8	-5.6	2.0e-08	-0.86	0.04	0.93	TRUE
14	METSIM	Adipose	MED20	0.13	0.11	enet	27	0.11	2.3e-16	6.3	5.5	3.2e-08	0.90	0.01	0.99	TRUE
6	GTEx	Esophagus Mucosa	MED20	0.09	0.07	enet	10	0.02	2.7e-02	-5.4	5.5	3.3e-08	0.96	0.03	0.96	TRUE
9	GTEx	Heart Left Ventricle	MED20	0.22	0.19	enet	8	0.12	5.8e-07	6.1	6.3	3.6e-10	0.98	0.01	0.99	FALSE
8	GTEx	Heart Left Ventricle	PRICKLE4	0.11	0.05	lasso	4	0.03	9.8e-03	5.8	-6.2	4.4e-10	-0.96	0.02	0.93	FALSE
12	GTEx	Nerve Tibial	MED20	0.13	0.11	enet	8	0.10	1.5e-07	6.5	6.2	6.2e-10	0.98	0.01	0.99	FALSE
13	GTEx	Thyroid	MED20	0.05	0.05	lasso	2	0.02	8.1e-03	6.0	6.2	7.3e-10	0.97	0.02	0.98	FALSE
4	GTEx	Artery Tibial	MED20	0.14	0.11	lasso	2	0.09	9.7e-08	6.1	6.1	1.2e-09	0.98	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	BYSL	0.05	0.06	enet	7	0.06	4.3e-06	6.0	-6.0	2.1e-09	-0.91	0.00	1.00	FALSE
11	GTEx	Muscle Skeletal	MED20	0.16	0.15	lasso	4	0.16	6.7e-16	5.8	6.0	2.2e-09	0.92	0.07	0.93	FALSE
3	GTEx	Adipose Subcutaneous	MED20	0.08	0.07	enet	9	0.05	4.7e-05	6.2	5.9	3.0e-09	0.97	0.02	0.98	FALSE
16	YFS	Blood	BYSL	0.07	0.06	lasso	7	0.09	2.8e-28	6.1	-5.6	2.1e-08	-0.85	0.01	0.99	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MED20	0.15	0.11	blup	471	0.13	3.1e-15	-5.4	5.5	3.7e-08	0.84	0.02	0.98	FALSE
17	YFS	Blood	MED20	0.04	0.03	lasso	5	0.03	3.6e-11	5.8	5.5	3.7e-08	0.85	0.05	0.95	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	MED20	0.10	0.10	enet	21	0.09	6.0e-12	6.0	5.3	1.4e-07	0.93	0.01	0.99	FALSE