Best TWAS P=6.92e-15 · Best GWAS P=5.66e-12 conditioned to 0.0203
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C11orf63 | 0.12 | 0.11 | lasso | 5 | 0.10 | 2.3e-08 | 6.9 | -6.6 | 5.6e-11 | -0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Nerve Tibial | C11orf63 | 0.24 | 0.08 | enet | 18 | 0.22 | 6.2e-16 | 4.7 | -7.8 | 6.9e-15 | -0.66 | 0.17 | 0.83 | TRUE |
| 3 | GTEx | Testis | C11orf63 | 0.32 | 0.14 | lasso | 7 | 0.08 | 3.2e-04 | -5.8 | 6.5 | 8.6e-11 | 0.75 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | CRTAM | 0.10 | 0.04 | enet | 6 | 0.05 | 1.1e-03 | 2.9 | -5.4 | 6.8e-08 | -0.37 | 0.02 | 0.20 | FALSE |