TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Relative age of first facial hair
:
←
→
chr2:232,718,042-234,145,080
Best TWAS P=8.25e-09 · Best GWAS P=4.79e-08 conditioned to 0.36
232.8M
233M
233.2M
233.4M
233.6M
233.8M
234M
234.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
EIF4E2
0.03
0.03
enet
8
0.04
4.4e-08
5.3
-5.8
8.2e-09
-0.87
0.01
0.99
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
EIF4E2
0.03
0.01
blup
60
0.02
2.7e-03
3.8
-5.6
1.8e-08
-0.85
0.02
0.75
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
EIF4E2
0.03
0.01
blup
63
0.02
4.7e-03
5.3
-5.6
2.1e-08
-0.91
0.01
0.87
FALSE
1
GTEx
Artery Tibial
EIF4E2
0.09
0.06
lasso
1
0.05
1.7e-04
5.3
-5.3
1.5e-07
-0.97
0.01
0.98
FALSE