Best TWAS P=8.25e-09 · Best GWAS P=4.79e-08 conditioned to 0.36
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | EIF4E2 | 0.09 | 0.06 | lasso | 1 | 0.05 | 1.7e-04 | 5.3 | -5.3 | 1.5e-07 | -0.97 | 0.01 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EIF4E2 | 0.03 | 0.03 | enet | 8 | 0.04 | 4.4e-08 | 5.3 | -5.8 | 8.2e-09 | -0.87 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | EIF4E2 | 0.03 | 0.01 | blup | 60 | 0.02 | 2.7e-03 | 3.8 | -5.6 | 1.8e-08 | -0.85 | 0.02 | 0.75 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | EIF4E2 | 0.03 | 0.01 | blup | 63 | 0.02 | 4.7e-03 | 5.3 | -5.6 | 2.1e-08 | -0.91 | 0.01 | 0.87 | FALSE |