Best TWAS P=3.15e-17 · Best GWAS P=4.53e-51 conditioned to 1.35e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Putamen basal ganglia | RBP1 | 0.28 | 0.01 | enet | 47 | 0.01 | 1.6e-01 | 0.39 | 7.1 | 1.5e-12 | 0.15 | 0.06 | 0.07 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | RP11-219D15.3 | 0.18 | 0.02 | enet | 21 | 0.04 | 2.1e-02 | 4.29 | 5.2 | 2.0e-07 | 0.20 | 0.20 | 0.07 | TRUE |
| 3 | GTEx | Nerve Tibial | RBP1 | 0.19 | 0.03 | lasso | 10 | 0.04 | 1.1e-03 | 2.69 | 6.7 | 1.7e-11 | 0.25 | 0.13 | 0.28 | TRUE |
| 4 | GTEx | Pancreas | RBP1 | 0.17 | 0.03 | lasso | 8 | 0.03 | 1.7e-02 | 5.25 | -5.3 | 1.4e-07 | -0.14 | 0.26 | 0.04 | FALSE |
| 5 | GTEx | Stomach | RP11-219D15.3 | 0.22 | 0.17 | lasso | 4 | 0.19 | 1.5e-09 | 4.25 | 8.4 | 3.2e-17 | 0.31 | 0.97 | 0.02 | TRUE |