Hub : Genes

RBP1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1350	0.0390	1.5e-06	0.077	0.029	0.076	0.082	0.087	1.1e-09	1.6e-04	1.7e-09	3e-10	9.7e-11
2	GTEx	Artery Tibial	0.1432	0.0531	2.8e-03	-0.002	NA	0.009	NA	0.012	5.1e-01	NA	5.7e-02	NA	3.7e-02
3	GTEx	Brain Putamen basal ganglia	0.2840	0.1020	8.9e-03	0.008	NA	0.012	NA	0.002	2.1e-01	NA	1.6e-01	NA	2.8e-01
4	GTEx	Heart Atrial Appendage	0.1960	0.0650	3.2e-04	0.058	NA	0.049	NA	0.076	1.4e-03	NA	2.9e-03	NA	2.7e-04
5	GTEx	Muscle Skeletal	0.2754	0.0721	1.6e-04	0.120	NA	0.071	NA	0.088	8.3e-12	NA	1.7e-07	NA	5.4e-09
6	GTEx	Nerve Tibial	0.1899	0.0673	9.9e-04	0.031	NA	0.008	NA	0.038	2.9e-03	NA	8.4e-02	NA	1.1e-03
7	GTEx	Pancreas	0.1710	0.0590	1.2e-03	0.029	NA	0.027	NA	0.032	2.2e-02	NA	2.5e-02	NA	1.7e-02
8	TCGA	Breast Invasive Carcinoma	0.1371	0.0405	0.0e+00	0.114	0.124	0.133	NA	0.130	1.6e-22	2.1e-24	3.6e-26	NA	1.5e-25
9	TCGA	Ovarian Serous Cystadenocarcinoma	0.0440	0.0250	9.1e-03	0.020	0.018	0.048	NA	0.035	1.6e-02	2.1e-02	3.6e-04	NA	1.9e-03
10	TCGA	Prostate Adenocarcinoma	0.0678	0.0339	1.8e-03	0.038	0.034	0.039	NA	0.048	6.7e-05	1.7e-04	6.1e-05	NA	8.3e-06
11	TCGA	Testicular Germ Cell Tumors	0.1750	0.0680	7.7e-05	0.051	0.154	0.144	NA	0.141	7.0e-03	4.2e-06	8.6e-06	NA	1.1e-05
12	TCGA	Thyroid Carcinoma	0.0890	0.0410	4.9e-04	0.030	0.028	0.026	NA	0.022	5.4e-04	8.7e-04	1.3e-03	NA	3.1e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.6	1.0	4.0	-0.1	-1.0	0.3	0.1	0.4	1.6	0.1	-1.2	0.1	-2.0	-0.7	1.6
Bipolar Disorder or Schizophrenia	0.2	0.6	2.6	0.1	0.2	-0.2	1.3	-0.1	-0.3	-1.5	0.0	0.5	-0.2	1.6	-0.3
Depressed Affect (Nagel 2018)	0.5	1.1	3.3	0.7	0.2	-0.2	1.4	1.4	1.3	-1.4	0.6	1.8	-0.5	0.8	-0.1
Depression (Nagel 2018)	0.9	1.4	4.1	0.4	0.2	0.4	1.8	0.6	-0.6	-1.7	1.0	1.5	0.6	2.0	-1.2
Intelligence (Savage-Jansen 2018)	0.5	1.6	5.4	-0.5	1.1	2.2	1.1	-1.6	0.3	-1.0	0.6	-0.2	2.3	1.0	-0.9
Neuroticism (Nagel 2018)	0.2	0.6	1.9	-0.4	-0.9	-0.2	1.4	0.4	0.7	-0.7	-0.8	0.6	-0.8	0.6	-1.0
Schizophrenia (2018)	1.0	2.0	6.9	0.2	1.1	-0.4	1.6	-0.5	-1.7	-1.9	1.0	0.6	1.4	2.6	-1.7
Schizophrenia vs Biploar Disorder	0.8	1.1	6.1	-1.0	1.2	-0.3	-0.1	-2.5	-0.6	-0.2	0.0	-1.5	0.7	0.7	-0.9
Worry (Nagel 2018)	0.2	0.4	1.6	-0.8	-1.2	-0.0	0.4	-0.6	0.3	-0.2	-1.3	-0.0	-0.6	-0.4	-0.6
Alzheimer’s Disease (in mother)	2.2	2.6	10.4	0.5	0.5	-1.0	-3.2	0.8	-0.7	2.7	-0.5	-0.9	-1.1	-2.0	2.1
Alzheimer’s Disease (in father)	1.1	1.2	3.2	-0.5	-0.9	-0.4	-1.0	-0.8	-0.9	0.6	-1.4	-0.6	-1.5	-1.8	1.6
Alzheimer’s Disease (including proxy)	2.2	3.2	9.7	-0.3	-0.7	-0.8	-3.1	-0.2	-1.2	2.3	-1.5	-1.4	-1.8	-2.5	2.5
Crohns Disease (2017)	0.5	1.0	3.7	-1.3	-0.5	-1.9	0.6	-1.1	-1.3	-0.7	0.0	-0.8	1.1	0.6	-0.9
Irritable Bowel Disease (IBD)	0.3	0.8	3.5	-1.2	-1.4	-0.8	0.3	-1.0	-1.9	-0.5	-0.6	-0.5	0.5	0.1	-0.5
Ulcerative Colitis (UC)	0.2	0.4	2.0	-0.5	-1.2	0.5	0.2	-0.4	-1.4	-0.4	-0.5	-0.0	0.5	-0.1	-0.1
Major Depression (MDD)	0.6	0.7	1.4	0.8	0.7	-0.4	0.7	1.1	1.1	-1.2	0.9	1.2	0.3	0.1	0.9
Reaction Time	0.2	0.4	2.7	-0.0	0.1	1.6	0.2	-0.1	0.9	0.4	0.4	0.0	-0.1	-0.1	-0.8
Verbal and Numeric Reasoning (VNR)	0.7	1.8	6.6	-0.4	1.1	0.6	1.4	-1.6	0.1	-1.0	1.1	-0.3	2.6	1.8	-1.7
Breast Cancer	0.7	1.7	6.9	-1.0	-0.8	-0.4	-1.6	-1.1	-0.3	2.6	-1.6	-1.9	-0.1	-0.6	-1.1
Ovarian Cancer	0.8	1.1	2.6	1.6	1.6	-0.2	0.4	1.4	0.9	0.7	1.5	0.4	0.8	1.1	-0.8
Prostate Cancer	0.2	0.3	0.9	-0.5	0.9	-0.2	0.6	-0.7	0.7	-0.6	-0.5	0.1	0.7	0.4	-0.6
Age at First Birth	1.0	1.4	3.3	-1.0	-1.2	1.7	-1.1	-1.4	-0.4	0.5	-1.5	-0.9	-1.8	-0.9	1.1
Bipolar Disorder (2011)	0.5	0.5	2.3	-0.1	-0.6	-0.2	0.8	0.3	-1.5	-0.7	-0.3	0.7	-1.0	0.3	0.3
Body Mass Index (BMI) (2010)	0.4	0.6	1.7	1.0	0.3	-0.7	-1.1	1.1	0.0	1.3	0.7	0.3	-0.2	0.5	-0.0
Coronary Artery Disease (CAD)	0.5	0.6	1.7	-0.0	-1.3	-0.6	-0.1	0.3	-0.9	-1.1	-0.3	0.7	-1.0	-0.4	1.0
Crohns Disease (2012)	0.6	0.9	3.5	-1.3	-1.0	-1.9	0.5	-0.6	-1.1	-1.3	-0.4	-0.3	0.7	0.5	-0.2
Mean Putamen Volume	0.4	0.4	1.5	-0.1	-0.4	-0.4	-0.8	-0.4	0.5	1.2	-0.7	-0.8	-1.0	-0.2	0.5
Fasting Glucose	0.6	0.7	2.7	1.1	-0.1	-0.7	-0.1	1.3	1.6	0.3	0.8	1.1	-0.1	-0.0	0.3
HbA1C	0.3	0.3	0.9	0.6	-0.0	-0.4	0.4	0.9	0.6	-0.4	0.3	0.9	0.5	0.5	-0.6
HDL Cholesterol	0.5	0.8	3.6	-0.9	0.7	-0.1	0.5	-1.9	0.2	-0.5	0.2	-1.0	1.5	-0.7	-0.2
LDL Cholesterol	0.9	1.5	3.0	-1.7	-1.3	-1.2	-1.3	-0.8	-0.6	1.3	-1.7	-1.7	-0.9	-0.7	0.4
Lupus	0.9	1.3	4.3	-0.4	1.2	-0.5	1.3	-0.4	0.8	-0.8	0.1	-0.2	1.9	1.7	-2.1
Neuroticism (2016)	0.5	0.8	4.8	-0.2	-1.0	-0.1	0.5	0.9	2.2	-0.9	-0.3	1.0	-0.4	-0.2	0.2
Primary Biliary Cirrhosis	1.5	2.1	5.4	-0.5	-2.1	-1.8	-1.1	0.2	0.7	0.4	-1.5	-0.1	-2.3	-2.1	1.9
Rheumatoid Arthritis	0.9	1.2	6.2	-1.2	-1.0	-2.5	-0.3	-1.2	-1.3	0.1	-0.7	-1.1	0.6	-0.2	-0.7
Schizophrenia (2014)	0.5	1.1	2.8	-0.8	0.8	-0.6	0.7	-1.6	-1.2	-1.7	0.4	-0.2	0.6	1.6	-1.2
Triglycerides	1.8	2.9	6.9	-2.2	-2.5	-1.0	-1.2	-1.1	0.9	2.0	-2.6	-2.2	-1.9	-0.5	0.1
Type 2 Diabetes (T2D) (2012)	1.4	1.6	3.5	-0.3	0.7	-1.7	1.0	-1.4	-1.9	0.4	1.1	-1.0	0.8	1.8	-1.9
Ulcerative Colitis	0.6	0.8	3.6	-1.0	-1.9	-0.1	-0.3	-0.8	-0.0	-0.3	-1.1	-0.2	-0.6	-1.3	0.9
Blood Eosinophil Count	0.0	0.1	0.4	-0.7	-0.2	0.6	0.2	-0.3	-0.0	-0.3	0.2	-0.2	-0.1	0.4	-0.4
Blood Platelet Count	0.1	1.2	3.1	0.8	-0.7	0.9	-1.2	1.7	1.1	1.0	0.0	0.6	-1.5	-0.1	1.8
Blood Red Count	0.2	2.0	4.6	-1.8	0.0	0.3	1.9	-1.9	-1.3	-1.5	-0.0	-1.1	1.0	1.4	-2.1
Blood White Count	0.2	1.1	3.8	1.4	-0.7	0.7	0.9	1.9	0.6	-0.4	1.0	1.6	-0.4	1.2	0.2
Heel T-Score	0.2	1.4	4.4	0.9	1.8	1.6	0.4	0.4	0.3	-0.7	1.5	0.3	1.2	2.1	-1.3
BMI	0.8	4.4	8.8	2.2	1.9	1.9	3.0	2.3	1.1	-2.2	2.6	2.9	1.1	1.9	-0.4
Height	0.2	3.2	6.9	-1.8	-2.6	1.5	2.1	-2.3	-2.6	-1.8	-1.0	-0.4	0.9	1.1	-1.6
Waist Hip Ratio (WHR)	0.4	1.8	6.4	1.0	1.4	-1.0	0.7	1.1	-2.5	-1.7	1.5	1.5	1.2	0.7	-0.2
Systolic Blood Pressure	0.3	1.6	5.0	1.2	0.8	-0.7	-2.2	2.0	0.9	1.7	1.1	0.6	-0.2	-1.2	0.7
Smoking Status	1.2	2.9	9.6	0.3	1.1	0.9	2.5	0.7	0.2	-3.1	1.8	2.1	1.4	2.4	-1.1
Allergy or Eczema	0.5	1.2	5.7	0.6	1.2	0.1	0.8	0.6	0.4	-0.3	0.8	0.2	2.4	1.9	-1.3
Cardiovascular Disease	0.3	0.8	3.9	1.0	-0.2	-0.5	-0.5	2.0	-1.3	-0.0	0.8	1.3	-0.7	-0.2	0.4
Hypothyroidism (self reported)	0.6	1.5	5.2	0.9	1.7	1.0	0.8	0.1	0.4	-0.9	1.5	0.5	2.3	1.6	-1.1
Respiratory disease	1.2	2.8	7.8	1.9	2.0	-0.4	2.8	1.6	0.4	-1.5	2.0	2.0	1.0	2.0	-0.5
Type 2 Diabetes (T2D) (2018)	1.1	2.0	6.9	1.1	0.8	-0.4	1.5	1.2	-1.1	-2.6	1.8	2.1	1.3	0.7	-0.2
Lung FEV1/FVC ratio	0.7	3.4	8.2	1.7	2.7	1.2	1.7	0.8	-1.2	-1.1	2.1	1.0	2.9	2.1	-2.0
Lung FVC	0.2	0.8	2.0	-1.0	0.7	0.9	-0.8	-1.4	-0.4	1.1	-1.1	-1.4	0.7	-0.4	-0.6
Neuroticism	0.3	0.7	2.2	-0.2	0.1	-0.4	1.5	0.5	1.2	-1.4	-0.2	1.1	-0.7	0.6	-0.7
Chronotype (morning person)	1.3	2.9	9.4	-0.4	-1.8	-1.0	-2.1	0.3	0.0	1.4	-1.3	-0.5	-3.1	-2.3	2.8
Hair Pigment	0.1	2.6	6.3	2.0	2.4	-0.7	1.6	1.7	-0.9	-0.8	2.5	1.8	1.0	1.9	-0.5
Tanning	0.1	1.2	5.3	1.1	-0.3	2.0	0.4	1.3	2.3	-0.0	0.4	1.0	0.8	0.2	-0.2
Hand grip strength (left)	0.3	0.8	4.6	-0.5	-0.8	-0.8	-0.1	-0.5	-2.2	-0.9	-0.7	0.1	-0.3	-0.1	1.1
Number of treatments/medications taken	0.3	0.6	2.7	0.9	0.7	-0.1	0.2	1.6	0.6	0.1	0.8	0.9	0.4	0.7	0.2
Average weekly spirits intake	0.1	0.1	0.4	-0.2	-0.0	-0.4	-0.4	-0.6	0.5	0.2	-0.4	-0.4	-0.3	-0.3	0.4
Sensitivity / hurt feelings	0.6	1.0	3.3	-1.2	-1.8	0.7	1.0	-0.0	1.2	-0.7	-1.3	0.2	-1.0	0.4	-0.7
Frequency of depressed mood in last 2 weeks	1.4	2.0	4.3	1.6	0.2	0.1	1.4	2.1	1.1	-1.1	1.8	2.1	0.7	1.9	-1.2
Hearing difficulty/problems: Yes	3.8	5.7	11.3	2.4	2.3	2.4	2.9	2.2	1.4	-3.2	3.2	3.4	1.8	1.4	-0.1
Relative age of first facial hair	0.7	1.5	6.2	1.3	0.4	-0.3	0.7	1.7	2.5	-1.2	0.6	1.5	-0.2	-0.6	1.5
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	4.9	0.4	0.0	0.8	-0.1	0.3	2.2	0.1	-0.6	0.2	0.3	-0.4	0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.5	-0.1	-0.2	-0.3	0.4	-0.1	-0.2	-0.7	-0.0	0.1	0.1	0.1	0.5
Ever had hysterectomy (womb removed)	0.8	0.9	3.4	0.7	0.0	-0.1	-0.7	1.1	0.6	-0.7	-0.4	1.3	-1.1	-0.9	1.8
Systolic blood pressure, automated reading	0.3	1.0	3.5	0.5	0.6	-0.3	-1.9	1.6	-0.2	1.2	0.5	0.3	-0.6	-1.2	1.0
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.1	-0.0	0.4	-1.1	1.4	-0.5	-1.3	-0.4	1.3	-0.2	1.0	0.5	-1.3
Angina	1.0	1.3	3.8	1.2	0.8	1.1	-0.3	1.9	1.6	-0.7	0.2	1.7	-0.4	0.0	1.5
Medication for hormone replacement therapy	1.0	1.1	2.0	-1.2	-1.4	-1.0	-0.5	-1.3	-0.6	0.9	-1.2	-1.1	-0.7	-1.4	0.8
Vitamin and mineral supplements	0.3	0.4	1.7	0.5	0.5	0.3	-1.3	-0.3	0.4	0.8	0.3	-0.6	-0.2	-0.5	0.7
Supplements: Zinc	1.1	1.2	3.8	-0.9	0.6	1.6	1.9	-0.9	0.4	-0.4	-0.2	-0.7	0.6	1.1	-1.8
Medication: Co-codamol	2.1	2.4	8.6	2.6	1.1	0.2	0.0	2.9	1.4	0.4	1.7	2.0	-0.6	1.6	0.9
Medication: Metformin	0.4	0.6	1.9	0.2	0.2	-1.2	0.3	0.2	-1.4	-1.4	0.8	1.0	0.1	0.6	0.1
Diabetes (father)	1.2	1.5	5.2	0.2	0.4	-2.0	1.0	-0.8	-2.3	-1.7	1.7	0.7	0.7	0.5	0.1
Diabetes (mother)	2.2	2.8	5.3	1.5	2.0	0.6	2.1	0.8	-0.6	-1.7	2.0	1.5	2.3	2.3	-1.4
Severe depression (siblings)	0.7	0.8	2.1	-1.1	-0.7	0.8	1.3	-0.5	-1.4	-1.4	-0.2	0.2	0.2	0.8	-0.5
Pack years adult smoking proportion	0.5	0.7	2.6	0.6	0.6	-1.3	-0.3	1.6	-0.7	0.0	0.9	0.7	-0.8	0.8	0.9
Impedance of leg (right)	1.5	7.2	12.9	-3.1	-2.0	-3.1	-3.1	-2.8	-2.2	2.2	-3.2	-3.6	-2.2	-2.7	1.1
Leg fat-free mass (left)	0.8	4.1	11.3	1.2	0.3	2.0	3.4	0.5	-1.0	-2.4	2.2	2.1	2.5	2.4	-2.0
Trunk fat percentage	0.1	0.5	1.8	0.4	0.6	0.5	1.1	0.2	-1.3	-0.2	1.0	0.2	0.1	0.7	-0.7
Hand grip strength (right)	0.3	0.8	1.9	-0.8	-1.2	0.1	-0.7	-1.0	-1.4	-0.1	-1.4	-0.7	-0.4	-0.6	0.9
Townsend deprivation index at recruitment	0.5	0.7	4.5	0.6	0.2	0.1	0.2	1.3	2.1	-0.4	0.0	1.0	0.1	-0.3	0.5
Current tobacco smoking	0.2	0.3	2.6	-0.1	0.4	0.3	0.1	-0.2	1.6	-0.2	0.2	0.1	-0.1	0.7	0.0
Average weekly fortified wine intake	1.0	1.2	3.1	-1.0	-0.3	-1.2	-0.7	-1.8	-1.5	1.0	-0.6	-1.7	0.3	0.4	-1.1
Maternal smoking around birth	0.2	0.3	2.9	-0.0	-0.3	0.5	0.3	0.2	1.7	0.3	-0.0	-0.1	0.3	0.0	0.2
Fed-up feelings	0.2	0.4	0.9	0.0	-0.9	-0.9	0.9	0.6	0.1	-0.7	-0.5	0.8	-0.8	0.6	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.8	5.5	0.0	-0.3	1.0	2.4	0.0	-0.9	-2.3	0.4	1.2	0.2	2.3	-1.4
Relative age voice broke	0.4	0.7	3.0	0.3	-0.0	-1.2	0.3	0.6	0.8	-1.0	-0.0	0.7	-0.7	-0.7	1.7
Taking other prescription medications	0.1	0.2	1.1	-0.2	-0.3	-1.1	0.5	0.3	-0.3	-0.3	-0.2	0.2	-0.2	-0.0	0.5
Age when periods started (menarche)	0.1	0.3	0.9	0.4	-0.0	0.6	0.9	0.1	-0.0	-0.8	0.7	0.4	0.5	0.7	0.3
Bilateral oophorectomy (both ovaries removed)	1.2	1.3	4.8	0.8	0.2	0.6	2.0	0.1	-0.5	-1.2	0.9	0.9	1.0	2.2	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	7.3	-0.8	0.6	-0.1	-0.1	-1.1	-2.7	0.8	0.1	-1.2	0.7	1.0	-1.5
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	4.8	0.9	2.0	0.1	0.6	0.3	0.7	0.0	1.8	0.2	2.2	1.2	-1.7
Qualifications: CSEs or equivalent	0.8	1.0	5.1	-0.1	0.3	0.6	0.6	-0.7	-0.4	1.0	1.2	-0.9	1.5	0.6	-2.3
Serious illness, injury or assault to yourself	1.3	1.5	3.9	1.8	1.2	1.1	1.3	1.5	1.5	-0.9	1.1	2.0	-0.2	0.2	0.4
High blood pressure	0.5	1.4	6.6	1.6	0.2	0.2	-0.5	2.6	-1.2	-0.3	0.8	1.8	-1.0	0.3	0.9
Hayfever, allergic rhinitis or eczema	0.7	1.6	6.5	0.9	1.2	-0.5	1.3	0.6	0.2	-1.2	1.2	0.8	2.5	1.6	-1.2
Multivitamins +/- minerals	0.3	0.4	1.6	-1.1	-0.7	-0.2	1.2	-0.4	-0.2	-0.9	-0.6	0.2	-0.5	-0.1	-0.3
Stomach or abdominal pain in last month	0.6	0.8	1.9	-1.4	-0.1	-1.3	-0.1	-1.4	0.3	-0.2	-1.3	-1.0	-0.6	0.2	-0.5
Supplements: Glucosamine	1.0	1.3	3.1	-1.2	-0.8	-1.6	-1.2	-0.4	0.2	0.7	-1.7	-0.6	-1.2	-1.8	1.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	1.8	-0.7	-0.4	-0.5	0.6	-0.8	0.8	-1.4	-0.8	-0.0	0.2	0.3	0.3
Medication: Atenolol	0.4	0.5	1.0	1.0	-0.1	-0.9	-0.7	1.0	0.1	0.4	0.3	0.8	-0.8	-0.4	0.7
Medication: Levothyroxine sodium	0.4	0.7	4.0	0.6	1.2	0.5	0.2	0.4	0.7	-0.7	0.7	0.2	2.0	0.0	-0.4
Sitting height	0.5	3.6	14.2	-0.8	-2.3	1.3	3.8	-1.0	-1.5	-3.4	0.1	1.2	1.0	1.5	-1.5
Chronic bronchitis/emphysema (father)	0.6	0.7	1.9	0.6	0.1	0.5	-1.0	1.0	1.3	0.6	-0.4	0.4	-1.2	-0.6	1.4
High blood pressure (mother)	1.3	1.8	5.2	0.3	0.5	0.8	1.3	-0.4	-0.6	-1.9	1.2	0.8	2.1	2.3	-1.7
Body mass index (BMI)	0.5	2.3	5.7	2.4	1.5	1.2	1.1	2.4	-0.2	-0.5	2.3	2.1	0.3	1.3	0.0
Impedance of leg (left)	1.3	6.1	10.4	-2.6	-1.5	-3.0	-3.0	-2.5	-1.7	2.0	-2.9	-3.2	-2.4	-2.5	1.3
Leg predicted mass (left)	0.8	4.5	12.0	1.3	0.4	2.2	3.5	0.6	-1.0	-2.5	2.3	2.2	2.5	2.5	-2.1
Trunk fat mass	0.2	1.0	2.9	0.6	0.5	0.8	1.7	0.3	-1.5	-0.8	1.4	0.7	0.6	1.1	-1.0
Waist circumference	0.8	3.0	7.0	2.2	1.1	0.9	1.8	2.2	-0.8	-1.8	2.7	2.6	1.0	1.6	-0.4
Number of incorrect matches in round	0.4	0.6	2.2	-0.6	-0.9	-0.7	-0.2	0.3	-0.6	1.1	-1.2	-0.4	-1.5	-0.5	0.4
Past tobacco smoking	1.4	2.5	8.0	0.9	-0.4	-0.6	-2.0	0.6	0.9	2.8	-1.3	-0.8	-2.5	-1.9	2.0
Alcohol usually taken with meals	0.3	0.4	1.8	-0.3	1.3	-0.9	-0.3	-0.5	0.3	0.7	0.0	-0.7	0.8	-0.2	-0.6
Nervous feelings	0.4	0.8	4.3	-0.6	-2.1	0.3	0.1	-0.1	-0.1	-0.5	-1.7	0.4	-1.2	-0.4	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.6	0.2	0.3	-1.3	0.5	0.2	0.6	-0.7	0.7	0.6	0.5	0.7	-0.7
Hearing difficulty/problems with background noise	2.7	4.3	9.6	2.4	2.2	1.0	2.0	2.1	2.2	-2.3	3.1	2.7	0.8	1.9	-0.2
Hair/balding pattern: Pattern 2	2.7	3.4	10.7	-2.0	0.7	-3.2	-1.1	-1.6	-3.3	1.9	-1.0	-2.3	0.0	-0.1	-1.4
Had menopause	0.4	0.5	1.6	0.6	0.7	0.4	-0.1	0.4	1.0	-0.9	0.4	0.7	-0.5	-0.6	1.2
Had other major operations	1.0	1.2	4.8	1.4	-0.1	2.2	-0.8	1.3	1.7	0.8	0.7	0.7	-0.4	-0.1	0.7
Forced vital capacity (FVC)	0.4	1.6	5.9	-0.7	0.4	1.3	1.2	-2.1	-0.6	-0.5	0.0	-0.7	2.4	0.7	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	6.5	-1.3	-0.3	0.3	-1.0	-1.3	-2.6	1.3	-1.3	-1.7	-0.6	-0.3	-0.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.4	-0.4	-0.3	-0.3	-0.4	-0.5	0.1	0.4	-0.6	-0.6	0.0	0.3	-0.3
Qualifications: None of the above	0.3	0.7	2.8	0.2	0.1	0.4	0.8	0.6	0.8	-1.7	1.2	1.1	-0.3	0.9	0.1
Financial difficulties in last 2 years	1.1	1.5	3.7	1.9	1.3	0.4	-1.4	1.6	0.6	1.9	1.3	0.7	-0.7	0.1	0.9
Mouth/teeth dental problems	0.2	0.3	1.5	-0.1	0.6	-0.6	-0.3	-0.3	-1.2	0.5	0.0	-0.5	-0.3	-0.3	0.4
Heart attack	0.8	1.0	2.5	1.1	-0.2	-0.8	0.1	1.4	0.0	-1.1	-0.0	1.6	-0.8	-1.1	1.6
Allergy	0.5	1.1	2.2	-1.5	-1.1	0.7	-0.9	-1.3	-0.7	0.9	-1.1	-1.3	-1.1	-0.9	0.1
Pain all over the body in last month	0.4	0.4	1.5	-0.8	-1.2	0.7	-0.2	-0.4	-0.7	0.5	-0.4	-0.5	-0.1	-0.9	-0.2
Diabetes (self-reported)	0.3	0.5	1.6	0.5	0.2	-0.5	0.8	0.7	0.0	-1.3	0.9	1.1	0.6	0.5	-0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.4	-0.2	0.6	-0.7	-0.4	0.1	0.4	1.2	-1.0	-0.7	-0.2	-0.6	0.2
Medication: Ramipril	0.9	1.2	3.6	1.8	0.5	0.9	-0.1	1.9	0.6	-0.1	0.6	1.6	-0.7	-0.7	1.5
Medication: Simvastatin	1.7	2.4	6.3	2.2	0.7	1.3	0.9	2.4	1.2	-1.2	1.6	2.5	1.2	1.2	0.8
Fluid intelligence score	1.2	2.5	11.0	-0.4	1.6	-0.1	1.2	-1.9	-0.6	-0.7	1.8	-0.5	3.3	1.5	-2.3
Illnesses of siblings	1.1	1.5	6.7	-1.0	-2.6	-1.2	-0.8	-0.3	0.3	0.9	-1.8	-0.7	-1.7	-0.8	0.1
Neuroticism score	0.4	0.8	3.5	-0.2	-1.3	-0.7	0.6	0.8	1.9	-0.5	-0.7	0.8	-1.4	0.0	-0.2
Weight	0.6	3.0	7.4	1.4	0.5	1.6	2.7	1.1	-1.5	-2.0	2.1	2.1	1.3	2.0	-1.2
Impedance of arm (right)	0.6	2.8	7.9	-2.3	-1.5	-1.9	-1.1	-2.5	-0.3	1.1	-2.0	-2.8	-0.7	-1.2	-0.4
Arm fat percentage (right)	0.2	0.7	2.2	1.3	0.8	0.2	0.6	1.4	-0.8	0.1	1.5	0.9	0.0	0.4	-0.0
Trunk fat-free mass	0.5	3.1	7.2	0.5	-0.5	1.5	2.7	0.0	-1.7	-2.6	1.5	1.9	2.1	1.9	-1.7
Hip circumference	0.4	1.5	4.1	0.9	-0.3	1.7	2.0	0.7	0.3	-1.6	1.5	1.7	0.4	1.4	-0.6
Time employed in main current job	1.7	2.0	6.2	-1.6	-2.0	-2.1	-0.6	-1.0	-1.1	0.5	-2.5	-1.3	-1.5	-0.4	0.2
Alcohol intake versus 10 years previously	1.7	2.5	6.1	0.8	1.9	1.6	2.5	0.6	1.3	-1.8	1.8	1.4	1.3	2.0	-1.1
Father’s age at death	0.8	1.0	4.8	-0.8	-0.8	-0.5	-1.4	-1.2	-2.2	0.5	-0.4	-1.1	0.1	-0.9	0.4
Worrier / anxious feelings	0.1	0.2	1.9	0.1	-0.4	-0.3	0.0	0.1	1.4	0.4	-0.2	0.2	-0.2	-0.6	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.7	1.4	0.8	0.5	0.9	1.9	1.6	-0.5	1.3	1.6	0.2	1.9	-0.5
Falls in the last year	1.0	1.3	4.2	0.9	-1.1	-1.2	-1.6	1.0	-0.5	2.1	-0.1	-0.3	-1.2	-1.3	1.0
Hair/balding pattern: Pattern 3	12.3	18.4	50.1	2.4	1.4	7.1	4.8	1.3	6.7	-5.3	3.9	4.2	3.5	4.0	-1.8
Number of live births	0.7	1.0	5.0	-0.7	0.1	0.8	-0.9	-0.3	-2.2	0.3	-1.1	-0.6	-0.9	-1.1	1.2
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	10.4	0.4	1.5	1.4	1.7	-1.3	-0.9	-0.9	1.0	0.1	3.2	1.4	-2.2
Pulse rate	0.8	1.3	3.1	-1.0	-0.3	-1.8	-0.0	-0.8	-1.6	0.7	-0.4	-1.1	1.0	1.4	-1.8
Happiness	1.6	1.9	4.8	1.6	0.8	-0.6	1.1	1.1	0.4	-2.2	2.1	2.1	0.4	1.5	0.5
Noisy workplace	1.1	1.3	4.6	0.8	-0.4	1.2	0.2	2.1	-0.5	-1.1	0.6	1.6	-1.4	0.1	1.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.2	-0.8	0.4	0.0	-0.3	-1.1	-0.5	1.1	-0.9	-0.9	-0.8	-0.8	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.6	-0.0	-0.9	-1.2	-0.7	0.0	-0.2	-0.6	-0.6	0.5	-0.9	-0.7	1.2
Mouth/teeth dental problems: Dentures	0.5	0.8	2.4	0.8	0.5	0.3	-0.5	1.3	1.2	-1.2	0.9	1.6	0.1	0.3	0.7
Asthma	0.7	1.5	2.8	1.6	1.0	-0.7	1.6	1.7	1.1	-1.0	1.4	1.6	-0.6	1.0	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.9	0.7	-0.1	-0.7	1.0	0.4	0.4	-1.0	1.1	0.8	1.1	2.0	-0.6
Medication: Cholesterol lowering	0.3	0.5	1.2	0.7	0.8	1.0	0.1	1.1	-0.3	0.5	1.0	0.6	0.5	0.3	-0.0
Depression (self-reported)	1.4	1.7	4.2	1.0	-1.7	-1.6	-1.1	1.6	-0.0	-0.5	-0.3	1.6	-1.3	-0.9	2.0
Medication: Lansoprazole	0.7	0.8	3.1	0.8	-0.4	0.9	-0.3	1.2	1.8	1.0	0.4	0.4	-1.1	0.0	0.8
Prospective memory result	0.7	0.8	2.3	0.5	-0.6	-1.2	-0.3	1.3	1.1	-0.2	-0.7	0.7	-1.5	-0.2	1.0
Lung cancer (father)	1.1	1.3	3.2	0.3	0.3	1.0	1.7	0.3	0.5	-1.7	1.8	1.1	1.0	1.5	-0.8
Illnesses of mother	0.3	0.3	1.3	-0.3	-0.9	-0.3	-0.6	-0.0	0.6	0.8	-0.1	-0.5	-0.2	-1.1	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	6.3	0.2	0.5	0.9	1.3	-1.2	-1.3	-0.7	0.3	0.0	2.5	1.0	-1.6
Pulse wave Arterial Stiffness index	0.9	1.0	3.1	-0.0	-0.1	-1.2	-1.2	0.9	1.8	1.3	-0.8	-0.4	-1.1	-1.1	0.7
Impedance of arm (left)	0.6	2.8	8.0	-2.4	-1.5	-1.5	-0.6	-2.6	-0.7	1.1	-2.0	-2.8	-0.6	-1.1	-0.7
Arm fat mass (right)	0.4	1.6	3.8	1.5	0.8	0.7	1.7	1.3	-1.0	-0.9	1.9	1.5	0.6	1.3	-0.7
Trunk predicted mass	0.5	2.9	6.6	0.5	-0.6	1.4	2.6	0.0	-1.8	-2.5	1.4	1.8	2.1	1.9	-1.7
Standing height	0.6	5.5	13.0	-1.9	-2.0	0.8	3.6	-2.8	-3.1	-3.3	-0.2	0.1	2.0	2.0	-2.9
Length of working week for main job	0.2	0.2	0.6	-0.5	0.0	-0.7	-0.3	-0.6	0.2	0.5	-0.3	-0.8	0.1	0.5	-0.4
Exposure to tobacco smoke at home	0.6	0.7	2.8	0.6	-1.2	0.2	-1.4	0.8	0.3	0.1	-0.2	0.5	-0.4	-0.9	1.7
Breastfed as a baby	0.4	0.4	1.6	-0.3	1.1	0.0	-0.8	-0.2	-1.2	0.8	0.2	-0.6	0.2	-0.4	0.7
Tense / ‘highly strung’	0.4	0.6	2.8	-0.8	-1.7	-0.2	0.1	-0.3	0.1	-0.2	-1.5	-0.2	-1.1	-0.7	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.1	0.1	-0.4	-0.5	-1.1	0.6	1.1	0.7	-0.9	0.1	-1.3	-1.3	1.5
Hair/balding pattern: Pattern 4	7.7	18.7	36.8	-2.8	-2.1	-6.0	-4.7	-1.8	-5.2	6.1	-5.1	-4.7	-3.7	-4.6	1.8
Birth weight of first child	0.6	1.0	7.5	-0.9	-1.3	-0.7	-0.7	-0.2	-2.7	-0.3	-0.9	-0.0	-0.4	-0.6	0.1
Peak expiratory flow (PEF)	1.5	3.5	10.6	0.5	1.9	1.8	2.7	-1.1	-0.3	-1.9	1.5	0.6	3.3	1.9	-2.5
Pulse wave reflection index	0.6	0.8	1.9	1.3	0.7	-0.4	-0.1	1.2	1.4	-0.1	0.5	1.1	-0.4	-1.1	0.8
Ever highly irritable/argumentative for 2 days	0.9	1.1	3.7	-0.6	-1.3	-1.4	-1.1	-0.3	0.2	-0.2	-1.1	-0.0	-1.4	-0.7	1.9
Loud music exposure frequency	1.7	1.9	4.0	1.1	1.9	0.8	1.5	-0.0	1.3	-2.0	1.8	1.1	1.2	1.7	-0.4
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	3.7	-1.5	0.8	-1.5	-0.5	-1.9	-1.6	0.8	-1.1	-1.6	0.2	-0.2	-0.6
Mouth/teeth dental problems: Bleeding gums	0.8	1.0	3.3	-1.4	-0.2	-0.3	0.7	-1.8	-0.1	-0.5	-0.0	-1.4	1.5	0.0	-1.4
Blood clot in the leg (DVT)	1.6	2.1	7.7	-0.1	-1.2	-0.4	-2.5	-0.5	0.5	1.3	-1.3	-0.7	-1.1	-2.8	2.0
Medication: Paracetamol	0.8	1.3	7.2	1.7	0.1	-0.0	-0.1	2.7	1.0	0.5	0.3	1.6	-0.8	0.6	0.8
Headache pain in last month	2.5	4.4	8.8	-1.8	-1.8	-1.8	-2.2	-0.6	1.0	2.6	-2.9	-1.9	-3.0	-2.5	1.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.4	-0.2	0.1	-0.8	0.8	-1.0	-0.3	-1.5	0.0	0.1	0.9	0.9	-0.9
Glaucoma (self-reported)	1.5	1.8	5.5	1.0	0.5	-1.6	-0.9	1.9	-1.1	-0.1	0.2	1.1	-2.0	-1.1	2.3
Gout (self-reported)	1.1	1.4	5.1	0.2	1.0	-1.2	0.8	-0.6	-0.9	0.4	1.6	-0.3	2.0	1.0	-2.3
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	7.3	0.3	1.1	1.0	1.2	-0.3	-0.1	-1.4	1.5	0.3	2.7	1.5	-1.7
Medication: Amlodipine	0.1	0.1	0.3	0.1	-0.1	-0.4	0.5	0.2	-0.5	-0.2	0.6	0.2	0.2	-0.4	-0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.7	0.7	-0.3	-0.8	0.3	1.3	0.1	-0.2	0.6	0.8	-1.3	0.0	0.8
Birth weight	0.3	0.6	2.5	0.5	-0.1	-0.4	1.1	0.0	-0.5	-1.6	0.3	1.2	0.6	0.8	-0.1
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.4	0.8	1.2	-0.5	0.0	0.7	0.8	0.3	0.4	0.4	-0.3	0.3	-0.0
High blood pressure (siblings)	1.1	1.7	8.8	0.5	3.0	1.9	-0.4	-0.3	-0.8	0.2	1.5	-0.2	1.8	0.2	-0.9
Forced vital capacity (FVC), Best measure	0.3	0.9	3.3	-0.7	-0.6	0.8	0.9	-1.7	-0.7	-0.4	-0.4	-0.5	1.8	0.5	-1.2
Body fat percentage	0.1	0.4	1.6	0.7	0.7	0.4	0.7	0.7	-1.3	0.0	1.0	0.4	-0.2	0.4	-0.1
Leg fat percentage (right)	0.1	0.4	2.8	0.4	0.4	-0.3	-0.2	0.8	-1.7	0.5	0.7	0.2	-0.7	-0.1	0.4
Arm fat-free mass (right)	0.7	3.8	8.9	0.8	0.5	1.8	3.0	0.1	-1.8	-2.6	1.9	1.9	2.4	2.4	-2.0
Exposure to tobacco smoke outside home	0.1	0.2	0.6	0.4	-0.5	0.0	-0.5	0.2	-0.6	0.8	-0.3	-0.4	0.1	-0.6	0.4
Comparative body size at age 10	1.0	2.8	5.6	1.6	1.1	2.0	2.1	1.5	1.1	-1.2	2.4	1.7	1.1	2.2	-1.5
Number of full brothers	0.9	1.2	3.5	1.4	1.0	1.8	0.2	1.0	1.9	-0.3	0.9	1.2	0.6	0.8	0.4
Worry too long after embarrassment	0.3	0.6	2.2	-0.3	-0.5	-0.3	1.0	-0.2	1.5	0.5	-0.6	-0.4	-1.0	0.4	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.0	0.2	-0.5	0.1	-1.1	1.1	0.3	0.4	-0.7	0.3	-0.8	-0.6	1.4
Wheeze or whistling in the chest in last year	0.1	0.1	0.4	-0.3	0.4	-0.2	0.3	-0.1	-0.1	0.6	-0.4	-0.5	-0.4	-0.2	-0.6
Number of children fathered	2.3	2.6	9.1	-1.1	-2.4	-0.4	-1.1	-0.4	-1.4	1.0	-1.8	-0.8	-3.0	-1.7	1.9
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.2	0.3	0.7	-1.1	0.4	-0.2	0.7	-0.3	0.5	0.2	0.4	0.4	-0.1
Age at first live birth	0.7	1.3	2.9	-1.3	-0.9	0.4	-0.5	-1.4	-1.7	0.8	-1.6	-1.1	-1.5	-0.7	0.5
Pulse wave peak to peak time	1.3	1.5	4.6	-0.3	-0.2	1.2	1.6	-1.3	-2.2	-1.6	0.7	0.3	1.4	1.2	-1.0
Health satisfaction	0.5	0.6	1.5	-0.2	0.5	-1.2	0.9	-0.9	0.3	-0.8	0.9	-0.4	1.0	0.8	-1.2
Shortness of breath walking on level ground	3.0	3.6	8.3	1.3	0.9	2.2	2.9	0.5	0.7	-2.2	2.5	1.9	2.2	2.0	-2.0
Qualifications: College or University degree	0.2	0.6	1.9	-0.0	-1.2	-0.3	-0.1	-0.5	1.4	-1.2	-0.6	0.4	0.7	-0.8	0.9
Eye problems/disorders: None of the above	1.5	1.7	5.0	-2.0	-0.7	-1.2	-0.5	-2.2	-1.2	1.0	-1.2	-2.2	-0.3	-0.6	-0.4
Mouth/teeth dental problems: Loose teeth	1.5	1.8	6.3	-0.1	0.4	2.4	2.5	-1.0	0.1	-0.5	0.7	0.1	0.9	1.6	-1.9
Emphysema/chronic bronchitis	2.7	3.0	5.4	0.7	1.8	1.7	2.3	-0.1	0.2	-2.2	2.1	1.2	2.2	2.3	-1.7
Medication for pain relief, constipation, heartburn	0.3	0.5	3.5	-0.7	-0.1	0.4	0.3	-0.9	-1.9	-0.6	0.1	-0.4	0.0	-0.5	-0.0
Neck or shoulder pain in last month	0.4	0.6	2.9	0.6	-0.1	-1.0	-0.1	0.7	1.7	0.4	-0.5	0.3	-0.7	-0.8	0.5
Medication: Blood pressure	0.9	1.5	4.5	1.6	0.8	0.3	-1.5	2.1	0.6	1.9	0.9	0.5	-0.8	-1.1	1.2
Angina (self-reported)	1.4	1.9	6.0	1.7	0.8	1.1	-0.4	2.5	1.8	-0.6	0.5	2.1	-0.5	-0.0	1.7
Migraine (self-reported)	0.2	0.2	1.4	0.4	0.7	-0.1	-0.3	0.2	-0.2	-0.1	0.2	0.2	0.2	1.2	-0.2
Medication: Ibuprofen	1.0	1.2	3.8	0.7	0.3	-0.7	1.1	0.7	0.6	-1.3	1.3	1.0	1.5	1.9	-0.7
Medication: Allopurinol	0.4	0.6	1.8	-0.3	0.5	-1.3	-0.5	-0.8	0.0	1.1	0.4	-1.0	0.5	-0.7	-0.7
Medication: Omeprazole	0.4	0.4	1.6	-1.0	-0.3	0.4	-0.3	-1.3	0.3	-0.2	-1.2	-0.6	-0.2	-0.7	0.1
Medication: Seretide 50 evohaler	0.9	1.0	3.3	0.4	-0.7	0.3	1.4	0.9	-0.8	-1.8	0.6	1.4	-0.3	1.3	-0.5
Mean time to correctly identify matches	0.5	1.0	4.7	-1.2	-0.6	2.2	-0.3	-1.2	0.4	0.6	-0.9	-1.0	-0.8	-0.9	-0.5
Heart disease (mother)	0.1	0.2	0.8	-0.4	0.5	-0.9	-0.3	-0.1	-0.1	-0.2	-0.4	-0.2	-0.1	-0.1	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.5	-0.2	0.6	-0.9	1.1	-1.1	0.2	-0.8	0.4	-0.5	1.2	0.7	-1.2
Whole body fat mass	0.2	0.9	2.4	0.9	0.6	0.5	1.4	0.6	-1.6	-0.6	1.5	0.9	0.4	1.0	-0.6
Leg fat mass (right)	0.2	0.9	3.1	1.0	0.5	0.4	1.1	1.1	-1.8	-0.5	1.4	1.1	-0.1	0.7	-0.1
Arm predicted mass (right)	0.6	2.9	6.1	0.9	0.5	1.7	2.5	0.3	-1.8	-2.1	1.8	1.8	2.2	1.9	-1.6
Pulse rate, automated reading	0.9	3.0	5.6	-1.6	-2.0	-2.4	-2.1	-0.5	-1.5	1.8	-2.3	-1.8	-1.3	-1.8	0.7
Alcohol intake frequency.	0.9	2.1	4.8	1.9	0.4	1.7	1.3	2.2	0.7	-0.9	1.6	2.1	-0.2	1.9	-0.2
Comparative height size at age 10	0.7	3.9	10.0	-1.6	-0.6	0.7	3.2	-1.9	-3.0	-3.0	0.2	0.2	1.7	1.8	-2.4
Number of full sisters	0.9	1.0	5.0	0.7	0.5	2.2	1.3	0.6	0.7	-0.3	0.9	0.7	0.3	1.4	-0.7
Suffer from ‘nerves’	0.2	0.3	2.9	-0.0	0.1	-0.1	0.2	-0.2	1.7	-0.0	-0.4	-0.0	-0.4	-0.2	0.1
Overall health rating	0.3	0.6	1.9	-1.1	-1.4	-0.0	0.1	-0.8	-0.7	0.5	-1.0	-0.7	-0.6	-0.5	-1.0
Chest pain or discomfort	0.4	0.6	1.8	0.2	0.2	-0.1	-1.3	-0.3	1.0	1.3	-0.7	-0.6	-0.3	-1.2	0.2
Had major operations	0.8	0.9	6.3	0.9	-0.5	2.5	-1.2	0.7	0.2	0.8	-0.1	0.4	-0.5	-0.6	0.6
Age at last live birth	0.4	0.6	2.5	-0.2	0.4	1.6	0.4	-0.2	-1.2	-1.4	0.2	0.6	-0.1	0.4	0.4
Family relationship satisfaction	2.2	2.7	5.7	1.8	1.5	0.1	2.4	1.0	0.1	-2.4	2.4	2.1	1.2	1.8	-0.3
Leg pain on walking	0.3	0.4	1.6	0.4	-0.5	0.1	1.1	0.4	1.3	-0.9	0.3	0.5	0.1	0.3	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.6	1.0	0.8	0.5	0.5	1.3	-0.4	-0.6	1.1	1.1	-0.1	0.4	0.8
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.7	-0.4	0.0	-0.5	-0.1	-0.6	0.0	0.9	0.2	-1.2	1.3	-0.5	-0.0
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	7.6	-2.8	-2.1	-1.2	-0.4	-2.3	-1.5	-0.0	-2.6	-2.2	-0.3	-0.8	-0.3
Medication: Aspirin	0.2	0.2	0.9	-0.3	0.4	-0.4	-0.6	-0.4	-0.5	0.4	-0.4	-0.6	0.0	-1.0	-0.0
Supplements: Vitamin C	1.0	1.2	3.0	0.8	0.6	1.1	1.7	1.0	1.1	-0.8	0.5	0.7	0.8	1.7	-1.3
Knee pain experienced in last month	0.6	0.9	3.7	0.1	-0.9	0.6	1.5	0.4	1.9	-0.7	-0.1	0.7	-1.1	1.2	-0.2
Hypertension (Self-reported)	0.5	1.5	7.1	1.6	-0.1	-0.0	-0.6	2.7	-1.4	0.0	0.7	1.8	-1.3	0.1	0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.6	-0.3	-0.2	-0.5	-0.5	-0.2	0.9	-0.2	-0.2	-0.1	-0.2	-0.7	1.3
Illnesses of father: Heart disease	1.2	1.6	4.9	-1.1	-0.6	-2.2	-1.3	-0.9	0.2	1.4	-1.9	-1.5	-1.0	-1.1	0.5
Illnesses of siblings: Diabetes	0.9	1.1	2.9	0.7	1.3	-0.5	1.6	0.7	1.2	-0.9	1.7	1.1	1.0	0.8	-0.6
Smoking status: Previous	1.7	2.6	7.1	-0.3	0.9	-0.2	2.0	-0.1	-1.5	-2.7	1.5	1.0	2.3	2.2	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	6.7	-1.1	-0.8	-0.6	2.0	-1.6	-1.0	-0.5	-0.4	-0.7	1.1	1.2	-2.6
Whole body fat-free mass	0.6	3.7	8.8	1.0	0.0	1.9	3.0	0.4	-1.4	-2.5	1.9	2.2	2.4	2.2	-1.9
Leg fat-free mass (right)	0.9	5.0	13.0	1.5	0.7	2.3	3.6	0.7	-0.7	-2.7	2.4	2.4	2.7	2.7	-2.2
Arm fat percentage (left)	0.2	0.9	2.9	1.4	1.1	0.4	0.9	1.3	-0.9	-0.1	1.7	0.9	0.3	0.7	-0.3
Average weekly red wine intake	1.0	1.4	3.8	-1.8	-1.1	0.3	-0.9	-1.7	-0.6	0.5	-2.0	-1.2	-0.2	-1.7	0.0
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.1	-0.1	0.3	-0.4	0.1	-0.3	0.7	-0.4	0.2	0.1	-1.1	0.0	0.5
Mood swings	0.6	1.0	4.6	0.3	-0.8	-0.1	-0.3	1.6	2.1	0.7	-0.5	0.6	-1.4	-0.8	0.8
Loneliness, isolation	1.1	1.5	3.9	1.8	1.0	0.6	0.4	1.4	1.4	-0.9	2.0	1.7	0.6	0.8	-0.3
Long-standing illness, disability or infirmity	0.6	0.9	2.8	1.0	-0.0	1.5	-0.7	0.9	1.7	-0.1	0.1	0.9	-0.8	-0.4	1.4
Ever had bowel cancer screening	0.7	0.9	3.1	-1.2	-1.8	0.7	0.9	-0.9	-0.9	-0.8	-1.3	-0.4	-0.4	-0.1	-0.3
Diabetes diagnosed by doctor	0.9	1.5	4.1	1.0	0.4	-0.9	1.2	1.1	-0.9	-2.0	1.6	1.8	0.9	1.0	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.8	-0.7	-0.2	0.8	-0.2	-0.6	-1.2	0.9	-1.0	-1.2	0.8	0.1	-1.3
Friendships satisfaction	2.4	3.0	9.3	3.0	2.0	-0.3	0.2	2.5	0.9	-0.7	2.5	2.4	0.6	1.1	1.0
Qualifications: nursing, teaching	0.6	1.0	3.9	-0.3	0.3	-0.1	-0.9	-0.6	0.3	2.0	-1.4	-1.4	0.2	-1.6	0.0
Commuting to job workplace: Walk	0.4	0.5	1.7	0.1	0.3	0.8	0.3	0.4	0.0	-1.2	-0.6	0.9	-1.3	-0.2	0.7
Eye problems/disorders: Cataract	2.1	2.4	4.9	1.3	1.4	2.2	1.9	0.9	0.6	-1.3	1.7	1.3	2.0	1.7	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.8	-0.4	-0.4	0.4	0.9	-0.6	0.8	-0.3	-0.4	-0.2	0.9	1.1	-1.3
Medication for cholesterol	0.3	0.4	1.4	0.1	1.1	0.5	-0.8	-0.3	1.2	0.7	0.3	-0.6	0.3	-0.2	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.8	-0.4	0.7	-0.4	0.3	-0.1	1.7	0.4	-0.2	-0.7	0.7	1.2	-1.3
Back pain experienced in last month	0.1	0.2	0.6	-0.5	-0.4	-0.2	0.7	-0.6	-0.3	-0.8	-0.1	-0.0	-0.6	0.2	-0.4
Mineral and other dietary supplements	0.2	0.2	0.7	0.5	0.4	-0.2	-0.4	-0.3	-0.1	-0.3	0.9	0.2	0.4	-0.6	0.7
Breast cancer (self-reported)	0.9	1.0	4.2	-1.0	-0.6	-0.5	-0.4	-0.5	0.1	-1.0	-1.3	-0.0	-1.1	-2.1	1.5
Asthma (self-reported)	1.0	1.9	4.7	2.1	1.4	-0.5	1.3	2.2	1.4	-0.8	1.6	1.8	-0.5	1.0	0.5
Osteoporosis (self-reported)	0.2	0.3	1.6	-0.2	-0.3	0.1	0.3	0.3	0.7	0.8	-0.3	-0.3	-1.3	-0.0	0.0
Osteoarthritis (self-reported)	0.7	0.9	2.1	0.7	-0.5	0.4	1.1	1.2	1.0	-0.8	0.8	1.5	-0.6	1.4	-0.6
Medication: Aspirin	0.5	0.7	1.5	-0.9	0.0	-0.8	-1.2	-0.9	-0.3	0.7	-0.9	-1.2	-0.0	-1.2	0.1
Medication: Gliclazide	0.5	0.6	1.4	0.3	0.1	1.1	1.0	0.4	-0.5	-1.2	0.4	1.0	1.2	-0.2	-0.4
Illnesses of father: None of the above (group 1)	0.8	0.9	3.4	-0.1	0.1	1.2	1.8	0.3	1.1	-1.0	0.5	0.6	0.7	1.3	-1.1
Smoking status: Current	0.2	0.3	2.7	-0.3	-0.1	0.3	0.3	-0.4	1.6	-0.3	0.0	0.1	-0.0	0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.8	0.2	2.0	-0.6	0.1	-0.8	-1.3	0.5	0.2	-0.7	1.0	-0.1	-0.7
Whole body water mass	0.7	4.1	10.1	1.1	-0.1	1.9	3.2	0.5	-1.4	-2.7	2.0	2.3	2.4	2.4	-2.0
Leg predicted mass (right)	0.9	5.0	12.5	1.6	0.7	2.2	3.5	0.7	-0.7	-2.6	2.5	2.4	2.7	2.8	-2.2
Arm fat mass (left)	0.4	1.5	3.4	1.3	0.8	0.6	1.8	1.1	-1.4	-0.9	1.9	1.4	0.7	1.4	-0.9
Number of self-reported non-cancer illnesses	0.5	0.8	2.9	1.2	-0.3	-0.0	-0.4	1.7	-0.3	0.4	0.2	1.2	-1.1	0.3	1.5
Average weekly champagne plus white wine intake	0.4	0.6	1.9	1.1	0.6	-1.1	-0.3	0.6	0.9	-0.2	1.4	0.8	-0.2	0.3	0.6
Miserableness	0.9	1.6	4.7	-0.4	-1.3	-2.2	-0.7	0.7	1.4	0.5	-1.3	0.2	-2.1	-1.3	1.3
Guilty feelings	0.9	1.3	4.1	1.4	0.4	-0.1	0.5	1.8	2.0	-0.1	1.6	1.3	0.1	1.0	-0.6
Wears glasses or contact lenses	0.9	1.0	2.5	-1.3	-0.4	1.6	-0.7	-1.2	-0.6	0.8	-1.3	-1.3	-0.2	-1.1	-0.3
Ever taken oral contraceptive pill	0.4	0.5	2.5	0.3	0.6	-1.6	-0.4	0.2	-1.0	1.0	0.2	-0.4	-0.4	0.6	0.3
Hearing aid user	0.9	1.1	3.2	1.2	0.2	1.8	0.2	1.7	1.0	-0.6	0.5	1.4	0.6	0.9	0.1
Mother’s age at death	0.9	1.1	3.3	-0.8	1.2	-1.8	-1.2	-1.1	-0.6	1.1	-0.8	-1.3	-0.6	-1.0	0.2
Financial situation satisfaction	1.6	1.9	7.6	1.5	1.2	1.2	1.1	0.5	-0.6	-0.9	2.8	1.1	1.8	1.6	-1.0
Tinnitus: Yes, now most or all of the time	0.6	0.7	4.5	-0.1	-0.8	-0.4	1.4	-0.1	-0.1	-2.1	0.3	0.8	-0.3	-0.1	0.3
Commuting to job workplace: Public transport	0.6	0.7	2.4	-1.3	-0.1	0.6	0.9	-1.4	-0.3	-0.3	-0.1	-0.8	0.2	0.7	-1.5
Eye problems/disorders: Glaucoma	1.3	1.5	4.8	0.6	-0.4	-1.1	-1.6	1.8	-0.5	0.4	-0.4	0.7	-1.8	-1.2	2.2
Medication: Blood pressure	0.3	0.6	1.5	0.3	-1.1	0.6	0.3	0.8	-1.2	-1.1	-0.4	1.1	-0.8	0.2	0.3
Pain type(s) experienced in last month: Hip pain	1.6	2.0	5.9	2.0	0.9	1.6	0.6	2.4	0.9	-0.7	1.4	2.4	-0.6	0.8	0.8
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.8	-0.7	-0.5	-0.3	0.0	0.3	0.3	0.9	-0.9	-0.5	-0.8	0.2	-0.5
High cholesterol (Self-reported)	1.0	1.9	5.2	0.4	1.7	-0.6	1.5	0.1	-1.8	-0.7	1.8	0.5	2.3	1.4	-1.6
Medication: Bendroflumethiazide	1.7	2.6	7.9	-0.1	-2.5	-1.1	-1.3	1.2	-0.3	1.1	-1.7	0.2	-2.8	-2.0	2.1
Medication: Paracetamol	1.2	1.8	6.7	1.7	0.4	0.5	1.1	2.6	1.3	-1.1	0.9	2.3	0.2	1.4	0.1
Medication: Lisinopril	0.4	0.5	1.4	-1.1	0.2	-0.8	-0.3	-1.0	0.0	0.1	0.0	-1.2	0.7	0.8	-0.6
Medication: Atorvastatin	0.9	1.1	4.6	-0.3	0.6	-1.5	-1.7	-0.1	-2.1	1.1	0.3	-1.2	0.1	-1.0	0.0
Illnesses of father: High blood pressure	1.1	1.3	4.0	-1.1	0.1	-0.8	-1.5	-1.6	-0.8	1.8	-0.4	-2.0	-0.2	-1.2	-0.4
Alcohol drinker status: Never	1.2	1.5	4.0	2.0	0.4	-0.0	-0.2	2.0	1.0	-1.0	1.3	1.9	-0.8	0.4	1.3
Ever smoked	1.6	2.8	8.2	-0.4	1.3	1.3	1.7	-0.5	-0.4	-2.7	1.6	1.1	2.9	2.0	-1.9
Basal metabolic rate	0.6	3.5	8.8	1.0	0.0	1.7	3.0	0.4	-1.5	-2.4	2.0	2.1	2.2	2.1	-1.8
Leg fat percentage (left)	0.1	0.5	1.7	0.7	0.7	-0.3	-0.1	1.0	-1.3	0.3	0.8	0.5	-0.8	0.1	0.4
Arm fat-free mass (left)	0.5	2.7	6.8	0.6	-0.1	1.4	2.6	0.2	-1.8	-2.4	1.5	1.8	1.8	1.9	-1.5
Number of operations (self-reported)	1.6	2.3	6.5	2.3	-0.2	2.5	-0.8	2.6	1.3	0.0	0.5	2.1	-0.9	-0.1	1.5
Average weekly beer plus cider intake	0.3	0.4	2.2	-0.4	-1.5	-0.4	1.0	-0.0	-0.3	-0.6	-0.9	-0.1	-0.1	0.0	-0.0
Irritability	1.1	1.9	8.6	-1.8	-2.9	-1.1	-0.3	-0.2	-0.4	0.4	-2.4	-0.7	-1.7	-0.9	-0.1
Risk taking	1.7	2.5	10.2	0.9	-0.9	-1.0	-2.2	1.1	0.5	0.8	-0.0	0.6	-1.6	-2.7	3.2
Ever had prostate specific antigen (PSA) test	0.9	1.0	3.9	-1.2	-1.1	0.4	0.7	-1.3	-2.0	0.1	-1.2	-0.9	-0.8	-0.0	-0.5
Fractured/broken bones in last 5 years	1.4	1.9	4.0	-0.9	-0.4	-0.3	-1.6	-0.6	-0.9	1.7	-1.6	-1.4	-2.0	-1.7	1.7
Age started oral contraceptive pill	1.2	1.6	5.9	-1.0	1.3	0.9	1.3	-1.7	-2.4	-1.2	-0.1	-0.8	0.6	1.1	-0.9
Diastolic blood pressure, automated reading	0.3	1.0	3.2	0.1	0.1	-0.4	-1.3	1.4	-0.5	0.3	-0.3	0.6	-1.1	-1.8	1.6
Ever depressed for a whole week	1.8	2.2	4.6	-0.7	-2.0	-1.1	-2.1	-0.5	0.1	1.4	-2.0	-1.2	-2.0	-1.6	1.6
Unable to work because of sickness or disability	0.6	0.8	3.2	-0.0	-0.7	-1.8	-1.7	0.3	-0.0	-0.2	-0.2	0.1	-0.5	-0.9	1.1
Commuting to job workplace: Cycle	0.6	0.7	4.3	-0.4	-1.1	0.4	-0.1	-0.3	0.0	0.4	-1.3	-0.1	-0.6	-2.1	0.6
Myopia	1.4	2.1	7.0	1.3	2.6	-0.4	1.4	-0.2	0.9	-1.2	2.2	1.0	2.0	1.2	-1.0
Vascular/heart problems diagnosed by doctor	0.6	1.7	7.7	-1.6	0.1	-0.6	0.5	-2.8	1.0	0.3	-0.6	-2.0	1.3	-0.1	-1.2
Cholesterol lowering medication	1.1	1.6	3.5	1.3	1.4	-0.0	1.1	1.3	-0.7	-1.3	1.5	1.4	1.4	1.9	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.3	-0.3	-0.5	0.1	-1.1	-0.3	1.1	0.6	-1.1	-0.5	-0.7	-0.6	0.8
Pain experienced in last month	0.4	0.6	3.4	-0.0	0.9	0.1	-0.5	-0.4	-1.2	-0.0	0.8	-0.4	1.9	0.3	-0.7
Supplements: Calcium	2.4	2.7	5.8	-2.2	-0.8	-2.2	-0.6	-1.9	-1.6	1.4	-2.4	-2.3	-1.0	-0.9	-0.8
Basal cell carcinoma (self-reported)	0.5	0.5	2.1	0.2	-0.3	-0.8	-0.7	-0.2	-1.2	-0.2	-0.2	0.4	-1.1	-0.5	1.5
Heart attack/myocardial infarction (self-reported)	0.7	1.0	2.7	1.1	-0.3	-0.8	0.2	1.3	0.0	-1.3	0.0	1.6	-0.5	-1.0	1.4
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	8.0	-0.2	-1.4	-0.5	-2.6	-0.5	0.7	1.4	-1.4	-0.7	-1.2	-2.8	2.0
Heart disease (siblings)	0.6	0.7	2.5	1.2	1.3	0.3	0.0	0.7	0.7	-0.5	0.6	0.6	1.6	0.8	-0.0
Alcohol drinker status: Previous	0.4	0.5	1.4	1.1	1.0	0.1	-0.2	0.5	-0.4	0.4	1.2	0.3	0.7	1.0	-0.5
Pack years of smoking	0.4	0.6	2.5	0.5	0.4	-0.7	-0.3	1.6	-0.6	0.2	0.8	0.6	-0.8	0.5	1.0
Impedance of whole body	0.9	4.4	11.2	-2.8	-1.4	-2.2	-1.7	-3.0	-1.3	1.5	-2.5	-3.3	-1.2	-1.6	0.0
Leg fat mass (left)	0.3	1.1	2.3	1.3	0.7	0.5	1.1	1.4	-1.5	-0.7	1.4	1.4	-0.2	0.7	0.1
Arm predicted mass (left)	0.5	2.4	5.7	0.7	-0.1	1.2	2.4	0.3	-1.8	-2.2	1.4	1.9	1.6	1.7	-1.3